PT2235159E - Processos de fermentação para cultivo de streptococcus e processos de purificação para obtenção de cps a partir deles - Google Patents

Processos de fermentação para cultivo de streptococcus e processos de purificação para obtenção de cps a partir deles Download PDF

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Publication number
PT2235159E
PT2235159E PT88642475T PT08864247T PT2235159E PT 2235159 E PT2235159 E PT 2235159E PT 88642475 T PT88642475 T PT 88642475T PT 08864247 T PT08864247 T PT 08864247T PT 2235159 E PT2235159 E PT 2235159E
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PT
Portugal
Prior art keywords
streptococci
purification processes
cps
obtaining
obtaining cps
Prior art date
Application number
PT88642475T
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English (en)
Inventor
Paolo Costantino
Francesco Norelli
Francesco Berti
Concetta Maria Cicala
Giulia Bazzocchi
Silvia Fontani
Roberto Olivieri
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Novartis Ag
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40042497&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT2235159(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PT2235159E publication Critical patent/PT2235159E/pt

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q3/00—Condition responsive control processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/32—Amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/34—Sugars
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/38—Vitamins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/42—Organic phosphate, e.g. beta glycerophosphate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/70—Undefined extracts
    • C12N2500/74—Undefined extracts from fungi, e.g. yeasts

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
PT88642475T 2007-12-20 2008-12-19 Processos de fermentação para cultivo de streptococcus e processos de purificação para obtenção de cps a partir deles PT2235159E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US894107P 2007-12-20 2007-12-20
GBGB0818453.3A GB0818453D0 (en) 2008-10-08 2008-10-08 Fermentation processes for cultivating streptococci and purification processes for obtaining cps therefrom

Publications (1)

Publication Number Publication Date
PT2235159E true PT2235159E (pt) 2015-05-13

Family

ID=40042497

Family Applications (1)

Application Number Title Priority Date Filing Date
PT88642475T PT2235159E (pt) 2007-12-20 2008-12-19 Processos de fermentação para cultivo de streptococcus e processos de purificação para obtenção de cps a partir deles

Country Status (12)

Country Link
US (3) US8445239B2 (pt)
EP (2) EP2235159B1 (pt)
JP (2) JP5465676B2 (pt)
CN (1) CN101932698B (pt)
AU (1) AU2008339553B2 (pt)
CA (1) CA2708878C (pt)
ES (1) ES2535080T3 (pt)
GB (1) GB0818453D0 (pt)
NZ (1) NZ586193A (pt)
PL (1) PL2235159T3 (pt)
PT (1) PT2235159E (pt)
WO (1) WO2009081276A2 (pt)

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GB201121301D0 (en) 2011-12-12 2012-01-25 Novartis Ag Method
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AR092897A1 (es) 2012-10-03 2015-05-06 Novartis Ag Composiciones inmunogenicas
CN104936615B (zh) 2012-11-21 2017-03-29 印度血清研究所私人有限公司 高产量的细菌多糖的制备
CA2918076A1 (en) 2013-07-11 2015-01-15 Novartis Ag Site-specific chemoenzymatic protein modifications
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EP3034516A1 (en) 2014-12-19 2016-06-22 Novartis AG Purification of streptococcal capsular polysaccharide
TWI718144B (zh) 2015-05-04 2021-02-11 美商輝瑞股份有限公司 Ｂ型鏈球菌多醣－蛋白質軛合物、製造軛合物之方法、含軛合物之免疫原性組成物、及其用途
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CN107760633A (zh) * 2017-11-30 2018-03-06 成都欧林生物科技股份有限公司 肺炎链球菌的固体培养基
WO2020117949A1 (en) * 2018-12-06 2020-06-11 Inventprise, Llc Bacterial growth on non-animal derived media
JP7239509B6 (ja) 2019-02-22 2023-03-28 ファイザー・インク 細菌多糖類を精製するための方法
JP2022525177A (ja) * 2019-03-14 2022-05-11 オーエム ファーマ 安定細菌抽出物を作製するプロセス及び医薬としてのその使用
CN115362177A (zh) 2020-02-21 2022-11-18 辉瑞公司 糖类的纯化
CN112198150B (zh) * 2020-07-07 2022-10-25 山东省临沂生态环境监测中心 生物发光法监测污染水体的方法
CN111893084A (zh) * 2020-08-21 2020-11-06 上海荣盛生物药业有限公司 肺炎链球菌高密度发酵培养基及其方法
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US9243271B2 (en) 2016-01-26
US8445239B2 (en) 2013-05-21
US20100272755A1 (en) 2010-10-28
EP2235159B1 (en) 2015-01-21
JP5465676B2 (ja) 2014-04-09
JP2014094012A (ja) 2014-05-22
AU2008339553B2 (en) 2014-04-17
WO2009081276A2 (en) 2009-07-02
US20140011183A1 (en) 2014-01-09
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CA2708878A1 (en) 2009-07-02
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AU2008339553A1 (en) 2009-07-02
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WO2009081276A3 (en) 2009-09-03

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