PT1732929E - Composto de benzopirano tricíclico enquanto agentes antiarrítmicos - Google Patents
Composto de benzopirano tricíclico enquanto agentes antiarrítmicos Download PDFInfo
- Publication number
- PT1732929E PT1732929E PT05727581T PT05727581T PT1732929E PT 1732929 E PT1732929 E PT 1732929E PT 05727581 T PT05727581 T PT 05727581T PT 05727581 T PT05727581 T PT 05727581T PT 1732929 E PT1732929 E PT 1732929E
- Authority
- PT
- Portugal
- Prior art keywords
- amino
- dihydro
- group
- pyrano
- trimethyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D515/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D515/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D515/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyrane Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
- Dental Preparations (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004084605 | 2004-03-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1732929E true PT1732929E (pt) | 2010-12-21 |
Family
ID=34962589
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT05727581T PT1732929E (pt) | 2004-03-23 | 2005-03-23 | Composto de benzopirano tricíclico enquanto agentes antiarrítmicos |
Country Status (31)
| Country | Link |
|---|---|
| US (2) | US7652008B2 (ko) |
| EP (1) | EP1732929B1 (ko) |
| JP (1) | JP4840594B2 (ko) |
| KR (2) | KR101085979B1 (ko) |
| CN (3) | CN1934116B (ko) |
| AT (1) | ATE485299T1 (ko) |
| AU (2) | AU2005223612B2 (ko) |
| BR (1) | BRPI0508768A (ko) |
| CA (1) | CA2558139C (ko) |
| CY (1) | CY1111250T1 (ko) |
| CZ (1) | CZ2006598A3 (ko) |
| DE (1) | DE602005024245D1 (ko) |
| DK (1) | DK1732929T3 (ko) |
| EG (1) | EG27163A (ko) |
| ES (1) | ES2353021T3 (ko) |
| HK (1) | HK1099299A1 (ko) |
| HR (1) | HRP20110005T1 (ko) |
| IL (1) | IL177950A (ko) |
| MX (1) | MXPA06010880A (ko) |
| NO (1) | NO339495B1 (ko) |
| NZ (2) | NZ549570A (ko) |
| PL (1) | PL1732929T3 (ko) |
| PT (1) | PT1732929E (ko) |
| RS (1) | RS51742B (ko) |
| RU (1) | RU2380370C2 (ko) |
| SI (1) | SI1732929T1 (ko) |
| SK (1) | SK287994B6 (ko) |
| TW (1) | TWI352704B (ko) |
| UA (1) | UA91189C2 (ko) |
| WO (1) | WO2005090357A1 (ko) |
| ZA (1) | ZA200607388B (ko) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CZ2006598A3 (cs) * | 2004-03-23 | 2006-11-15 | Nissan Chemical Industries, Ltd. | Tricyklická benzopyranová sloucenina jako antiarytmické cinidlo |
| RU2448112C2 (ru) | 2006-03-10 | 2012-04-20 | Ниссан Кемикал Индастриз, Лтд. | Способ получения оптически активного соединения оксида хромена |
| TW201022223A (en) * | 2008-08-14 | 2010-06-16 | Nissan Chemical Ind Ltd | Di-substituted benzopyrane compound |
| SG175377A1 (en) * | 2009-04-30 | 2011-12-29 | Nissan Chemical Ind Ltd | Novel crystal forms of tricyclic benzopyran compound and processes for producing same |
| WO2010151689A1 (en) | 2009-06-25 | 2010-12-29 | Alkermes, Inc. | Heterocyclic compounds for the treatment of neurological and psychological disorders |
| WO2014050613A1 (ja) * | 2012-09-27 | 2014-04-03 | 日産化学工業株式会社 | 含窒素複素環ｎ－オキシド化合物の製造方法 |
| CN104507949B (zh) * | 2012-09-27 | 2017-07-28 | 日产化学工业株式会社 | 高纯度的含氮杂环化合物的制造方法 |
| JPWO2015012271A1 (ja) * | 2013-07-25 | 2017-03-02 | 日産化学工業株式会社 | 複素環化合物の製造方法 |
| KR102009756B1 (ko) * | 2017-01-06 | 2019-08-12 | 고려대학교 세종산학협력단 | 신규한 퀴놀리논 유도체 및 이를 유효성분으로 포함하는 천식 또는 아토피 등의 알러지성 질환의 예방 또는 치료용 약학 조성물 |
| CN112423754A (zh) | 2018-03-05 | 2021-02-26 | 奥克梅斯制药爱尔兰有限公司 | 阿立哌唑的给药策略 |
| CN108727261B (zh) * | 2018-06-21 | 2021-09-24 | 济南大学 | 一种硝基取代喹那啶的制备方法 |
| JP7468869B2 (ja) * | 2018-12-28 | 2024-04-16 | 国立大学法人大阪大学 | 遺伝性徐脈性不整脈治療薬 |
| RU2754610C1 (ru) * | 2020-04-14 | 2021-09-03 | Георгий Викторович ТЕЦ | Препарат для лечения заболеваний, вызванных бактериями |
| US20230241053A1 (en) * | 2020-06-26 | 2023-08-03 | Osaka University | Therapeutic agent for drug-induced bradycardia and bradyarrhythmia |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZM7682A1 (en) | 1981-09-25 | 1983-05-23 | Beecham Group Plc | Active compounds |
| JPS5867683U (ja) | 1981-10-28 | 1983-05-09 | 株式会社ナムコ | 歩行ロボツト |
| JPH0699439B2 (ja) * | 1988-02-03 | 1994-12-07 | 日産化学工業株式会社 | ピラノベンゾオキサジアゾール誘導体 |
| JP2658198B2 (ja) | 1988-06-23 | 1997-09-30 | 日産化学工業株式会社 | ピラノベンゾトリアゾール誘導体 |
| US5097037A (en) * | 1989-07-17 | 1992-03-17 | Nissan Chemical Industries, Ltd. | Process for the optical resolution of pyranobenzoxadiazole compounds |
| JP2876712B2 (ja) * | 1989-07-17 | 1999-03-31 | 日産化学工業株式会社 | 光学活性ピラノベンゾオキサジアゾール誘導体 |
| US5164509A (en) * | 1990-11-26 | 1992-11-17 | E. R. Squibb & Sons, Inc. | Benzodiazolo analogs |
| CN1120313A (zh) | 1993-04-02 | 1996-04-10 | 日产化学工业株式会社 | 心脏器质性病变治疗药 |
| JPH07300414A (ja) * | 1993-04-02 | 1995-11-14 | Nissan Chem Ind Ltd | 心不全治療薬 |
| JP2734457B2 (ja) | 1994-02-23 | 1998-03-30 | 日産化学工業株式会社 | 不斉エポキシ化反応 |
| EP0764159B1 (en) | 1994-06-10 | 2000-08-09 | Smithkline Beecham Plc | C -4 amide substituted compounds and their use as therapeutic agents |
| ES2218617T3 (es) * | 1996-05-15 | 2004-11-16 | Aventis Pharma Deutschland Gmbh | Cromanos sustituidos con sulfonamida, procedimiento para su preparacion, su uso como medicamento o agente de diagnostico, asi como medicamentos que los contienen. |
| EP1085009B1 (en) | 1998-06-03 | 2004-11-10 | Nissan Chemical Industries, Ltd. | Indan derivatives |
| AU5444499A (en) | 1998-09-01 | 2000-03-21 | Nissan Chemical Industries Ltd. | Benzoxazine derivatives |
| AU2830800A (en) | 1999-03-25 | 2000-10-16 | Nissan Chemical Industries Ltd. | Chroman derivatives |
| HUP0202690A3 (en) | 1999-09-17 | 2005-02-28 | Nissan Chemical Ind Ltd | Benzopyran derivative having antiarrhytmic activity |
| WO2001021609A1 (en) | 1999-09-24 | 2001-03-29 | Nissan Chemical Industries, Ltd. | 4-oxybenzopyran derivative |
| US6677371B1 (en) | 1999-10-05 | 2004-01-13 | Nissan Chemical Industries, Ltd. | 4-oxybenzopyran derivative |
| TW589305B (en) | 2001-02-14 | 2004-06-01 | Nissan Chemical Ind Ltd | 4-aminobenzopyran derivatives |
| IL159218A0 (en) | 2001-06-25 | 2004-06-01 | Nissan Chemical Ind Ltd | Substituted benzopyran derivatives against arrhythmia |
| WO2003014113A1 (en) | 2001-08-06 | 2003-02-20 | Glenmark Pharmaceuticals Limited | Novel benzopyran compounds and process for their preparation and use |
| CZ2006598A3 (cs) * | 2004-03-23 | 2006-11-15 | Nissan Chemical Industries, Ltd. | Tricyklická benzopyranová sloucenina jako antiarytmické cinidlo |
-
2005
- 2005-03-23 CZ CZ20060598A patent/CZ2006598A3/cs unknown
- 2005-03-23 NZ NZ549570A patent/NZ549570A/en unknown
- 2005-03-23 WO PCT/JP2005/006004 patent/WO2005090357A1/en active Application Filing
- 2005-03-23 CA CA2558139A patent/CA2558139C/en not_active Expired - Fee Related
- 2005-03-23 SK SK5079-2006A patent/SK287994B6/sk not_active IP Right Cessation
- 2005-03-23 AT AT05727581T patent/ATE485299T1/de active
- 2005-03-23 BR BRPI0508768-6A patent/BRPI0508768A/pt not_active Application Discontinuation
- 2005-03-23 PL PL05727581T patent/PL1732929T3/pl unknown
- 2005-03-23 PT PT05727581T patent/PT1732929E/pt unknown
- 2005-03-23 CN CN2005800090295A patent/CN1934116B/zh active Active
- 2005-03-23 DK DK05727581.0T patent/DK1732929T3/da active
- 2005-03-23 RU RU2006137284/04A patent/RU2380370C2/ru not_active IP Right Cessation
- 2005-03-23 TW TW094108962A patent/TWI352704B/zh active
- 2005-03-23 AU AU2005223612A patent/AU2005223612B2/en not_active Ceased
- 2005-03-23 US US10/590,975 patent/US7652008B2/en active Active
- 2005-03-23 JP JP2006530022A patent/JP4840594B2/ja active Active
- 2005-03-23 SI SI200531171T patent/SI1732929T1/sl unknown
- 2005-03-23 CN CN2008101707921A patent/CN101429200B/zh not_active Expired - Fee Related
- 2005-03-23 NZ NZ585606A patent/NZ585606A/en unknown
- 2005-03-23 UA UAA200611101A patent/UA91189C2/ru unknown
- 2005-03-23 ES ES05727581T patent/ES2353021T3/es active Active
- 2005-03-23 CN CN2011100751168A patent/CN102190661B/zh not_active Expired - Fee Related
- 2005-03-23 RS RS20110028A patent/RS51742B/en unknown
- 2005-03-23 EP EP05727581A patent/EP1732929B1/en active Active
- 2005-03-23 KR KR1020107027058A patent/KR101085979B1/ko active IP Right Grant
- 2005-03-23 KR KR1020067021988A patent/KR101019402B1/ko active IP Right Grant
- 2005-03-23 MX MXPA06010880A patent/MXPA06010880A/es active IP Right Grant
- 2005-03-23 ZA ZA200607388A patent/ZA200607388B/en unknown
- 2005-03-23 DE DE602005024245T patent/DE602005024245D1/de active Active
-
2006
- 2006-09-02 EG EGNA2006000900 patent/EG27163A/xx active
- 2006-09-07 IL IL177950A patent/IL177950A/en not_active IP Right Cessation
- 2006-10-23 NO NO20064819A patent/NO339495B1/no not_active IP Right Cessation
-
2007
- 2007-06-15 HK HK07106502.1A patent/HK1099299A1/xx unknown
-
2009
- 2009-11-17 US US12/591,353 patent/US7964623B2/en not_active Expired - Fee Related
-
2010
- 2010-07-08 AU AU2010202900A patent/AU2010202900B2/en not_active Ceased
-
2011
- 2011-01-05 HR HR20110005T patent/HRP20110005T1/hr unknown
- 2011-01-19 CY CY20111100060T patent/CY1111250T1/el unknown
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