PT1656345E - Derivados cíclicos como moduladores da actividade de receptores de quimioquinas - Google Patents
Derivados cíclicos como moduladores da actividade de receptores de quimioquinas Download PDFInfo
- Publication number
- PT1656345E PT1656345E PT47818067T PT04781806T PT1656345E PT 1656345 E PT1656345 E PT 1656345E PT 47818067 T PT47818067 T PT 47818067T PT 04781806 T PT04781806 T PT 04781806T PT 1656345 E PT1656345 E PT 1656345E
- Authority
- PT
- Portugal
- Prior art keywords
- modulators
- chemokine receptor
- receptor activity
- cyclic derivatives
- cyclic
- Prior art date
Links
- 102000009410 Chemokine receptor Human genes 0.000 title 1
- 108050000299 Chemokine receptor Proteins 0.000 title 1
- 125000004122 cyclic group Chemical group 0.000 title 1
- 201000001320 Atherosclerosis Diseases 0.000 abstract 1
- 102100021943 C-C motif chemokine 2 Human genes 0.000 abstract 1
- 101710155857 C-C motif chemokine 2 Proteins 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 201000006417 multiple sclerosis Diseases 0.000 abstract 1
- 206010039073 rheumatoid arthritis Diseases 0.000 abstract 1
- 150000003839 salts Chemical group 0.000 abstract 1
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- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
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- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
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- C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
- C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
- C04B35/00—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
- C04B35/622—Forming processes; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
- C04B35/626—Preparing or treating the powders individually or as batches ; preparing or treating macroscopic reinforcing agents for ceramic products, e.g. fibres; mechanical aspects section B
- C04B35/63—Preparing or treating the powders individually or as batches ; preparing or treating macroscopic reinforcing agents for ceramic products, e.g. fibres; mechanical aspects section B using additives specially adapted for forming the products, e.g.. binder binders
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
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- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
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- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
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- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07D487/04—Ortho-condensed systems
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Manufacturing & Machinery (AREA)
- Physical Education & Sports Medicine (AREA)
- Ceramic Engineering (AREA)
- Pulmonology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Structural Engineering (AREA)
- Inorganic Chemistry (AREA)
- Virology (AREA)
- Materials Engineering (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Transplantation (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49694703P | 2003-08-21 | 2003-08-21 | |
| US10/923,619 US7163937B2 (en) | 2003-08-21 | 2004-08-19 | Cyclic derivatives as modulators of chemokine receptor activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1656345E true PT1656345E (pt) | 2013-12-27 |
Family
ID=34228609
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT47818067T PT1656345E (pt) | 2003-08-21 | 2004-08-20 | Derivados cíclicos como moduladores da actividade de receptores de quimioquinas |
Country Status (21)
| Country | Link |
|---|---|
| US (3) | US7163937B2 (enExample) |
| EP (1) | EP1656345B1 (enExample) |
| JP (1) | JP4795238B2 (enExample) |
| KR (1) | KR101120338B1 (enExample) |
| AU (1) | AU2004268968B2 (enExample) |
| BR (1) | BRPI0413713A (enExample) |
| CA (1) | CA2536384C (enExample) |
| DK (1) | DK1656345T3 (enExample) |
| ES (1) | ES2437104T3 (enExample) |
| HR (1) | HRP20131048T1 (enExample) |
| IL (2) | IL173824A (enExample) |
| IS (1) | IS8313A (enExample) |
| MX (1) | MXPA06001819A (enExample) |
| NO (1) | NO335946B1 (enExample) |
| NZ (1) | NZ545317A (enExample) |
| PL (1) | PL1656345T3 (enExample) |
| PT (1) | PT1656345E (enExample) |
| RS (1) | RS20060116A (enExample) |
| RU (1) | RU2006108867A (enExample) |
| SI (1) | SI1656345T1 (enExample) |
| WO (1) | WO2005021500A1 (enExample) |
Families Citing this family (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005506949A (ja) | 2000-12-20 | 2005-03-10 | ブリストル−マイヤーズ・スクイブ・ファーマ・カンパニー | ケモカイン受容体の調節剤としてのジアミン |
| AR035773A1 (es) | 2000-12-20 | 2004-07-14 | Bristol Myers Squibb Pharma Co | Compuestos diamino ciclico, composicion farmaceutica y su uso en la fabricacion de un medicamento util para modular la actividad de una quimioquina |
| WO2003075853A2 (en) | 2002-03-08 | 2003-09-18 | Bristol-Myers Squibb Company | Cyclic derivatives as modulators of chemokine receptor activity |
| US7291615B2 (en) | 2003-05-01 | 2007-11-06 | Bristol-Myers Squibb Company | Cyclic derivatives as modulators of chemokine receptor activity |
| US7163937B2 (en) * | 2003-08-21 | 2007-01-16 | Bristol-Myers Squibb Company | Cyclic derivatives as modulators of chemokine receptor activity |
| US7317019B2 (en) * | 2003-08-21 | 2008-01-08 | Bristol Myers Squibb Co. | N-alkylated diaminopropane derivatives as modulators of chemokine receptor activity |
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- 2004-08-20 RU RU2006108867/04A patent/RU2006108867A/ru not_active Application Discontinuation
- 2004-08-20 SI SI200432117T patent/SI1656345T1/sl unknown
- 2004-08-20 JP JP2006524092A patent/JP4795238B2/ja not_active Expired - Fee Related
- 2004-08-20 CA CA2536384A patent/CA2536384C/en not_active Expired - Fee Related
- 2004-08-20 KR KR1020067003442A patent/KR101120338B1/ko not_active Expired - Fee Related
- 2004-08-20 RS YUP-2006/0116A patent/RS20060116A/sr unknown
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- 2004-08-20 NZ NZ545317A patent/NZ545317A/en not_active IP Right Cessation
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- 2004-08-20 BR BRPI0413713-2A patent/BRPI0413713A/pt not_active IP Right Cessation
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