NO20060717L - Sykliske derivater som modulatorer av kjemokin reseptoractivitet - Google Patents

Sykliske derivater som modulatorer av kjemokin reseptoractivitet

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Publication number
NO20060717L
NO20060717L NO20060717A NO20060717A NO20060717L NO 20060717 L NO20060717 L NO 20060717L NO 20060717 A NO20060717 A NO 20060717A NO 20060717 A NO20060717 A NO 20060717A NO 20060717 L NO20060717 L NO 20060717L
Authority
NO
Norway
Prior art keywords
modulators
chemokine receptor
receptor activity
cyclic derivatives
cyclic
Prior art date
Application number
NO20060717A
Other languages
English (en)
Other versions
NO335946B1 (no
Inventor
Douglas Guy Batt
Soo Sung Ko
John V Duncia
Daniel S Gardner
Percy H Carter
Robert J Cherney
Anurag S Srivastava
Michael G Yang
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34228609&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20060717(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of NO20060717L publication Critical patent/NO20060717L/no
Publication of NO335946B1 publication Critical patent/NO335946B1/no

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    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
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    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
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    • C04B35/00—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
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    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
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    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
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    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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Abstract

Foreliggende søknad beskriver modulatorer av MCP-1 med formel (I): eller farmasøytisk akseptable saltformer derav, anvendelige for behandling av revmatoid artritt, multippel sklerose, aterosklerose og astma.
NO20060717A 2003-08-21 2006-02-14 Cykliske derivater, farmasøytiske preparater omfattende slike, slike forbindelser for anvendelse i terapi samt slike forbindelser for behandling av sykdommer NO335946B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US49694703P 2003-08-21 2003-08-21
US10/923,619 US7163937B2 (en) 2003-08-21 2004-08-19 Cyclic derivatives as modulators of chemokine receptor activity
PCT/US2004/027196 WO2005021500A1 (en) 2003-08-21 2004-08-20 Cyclic derivatives as modulators of chemokine receptor activity

Publications (2)

Publication Number Publication Date
NO20060717L true NO20060717L (no) 2006-05-16
NO335946B1 NO335946B1 (no) 2015-03-30

Family

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NO20060717A NO335946B1 (no) 2003-08-21 2006-02-14 Cykliske derivater, farmasøytiske preparater omfattende slike, slike forbindelser for anvendelse i terapi samt slike forbindelser for behandling av sykdommer

Country Status (22)

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US (3) US7163937B2 (no)
EP (1) EP1656345B1 (no)
JP (1) JP4795238B2 (no)
KR (1) KR101120338B1 (no)
AU (1) AU2004268968B2 (no)
BR (1) BRPI0413713A (no)
CA (1) CA2536384C (no)
DK (1) DK1656345T3 (no)
ES (1) ES2437104T3 (no)
HK (1) HK1087712A1 (no)
HR (1) HRP20131048T1 (no)
IL (2) IL173824A (no)
IS (1) IS8313A (no)
MX (1) MXPA06001819A (no)
NO (1) NO335946B1 (no)
NZ (1) NZ545317A (no)
PL (1) PL1656345T3 (no)
PT (1) PT1656345E (no)
RS (1) RS20060116A (no)
RU (1) RU2006108867A (no)
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US7829571B2 (en) 2010-11-09
PT1656345E (pt) 2013-12-27
JP4795238B2 (ja) 2011-10-19
EP1656345B1 (en) 2013-10-16
IS8313A (is) 2006-02-20
KR20060117903A (ko) 2006-11-17
NZ545317A (en) 2009-03-31
IL173824A (en) 2013-10-31
US20090124668A1 (en) 2009-05-14
IL173824A0 (en) 2006-07-05
BRPI0413713A (pt) 2006-10-17
DK1656345T3 (da) 2014-01-06
EP1656345A1 (en) 2006-05-17
PL1656345T3 (pl) 2014-03-31
IL228794A0 (en) 2013-12-31
SI1656345T1 (sl) 2014-01-31
NO335946B1 (no) 2015-03-30
JP2007502843A (ja) 2007-02-15
US7163937B2 (en) 2007-01-16
US20050054627A1 (en) 2005-03-10
AU2004268968A1 (en) 2005-03-10
CA2536384C (en) 2011-01-11
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US20070032526A1 (en) 2007-02-08
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WO2005021500A1 (en) 2005-03-10
US7482335B2 (en) 2009-01-27
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CA2536384A1 (en) 2005-03-10

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