PT106679B - Formulações tópicas de tetraciclinas, sua preparação e usos - Google Patents

Formulações tópicas de tetraciclinas, sua preparação e usos Download PDF

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Publication number
PT106679B
PT106679B PT106679A PT10667912A PT106679B PT 106679 B PT106679 B PT 106679B PT 106679 A PT106679 A PT 106679A PT 10667912 A PT10667912 A PT 10667912A PT 106679 B PT106679 B PT 106679B
Authority
PT
Portugal
Prior art keywords
formulation
topical
minocycline
suspension
microns
Prior art date
Application number
PT106679A
Other languages
English (en)
Portuguese (pt)
Other versions
PT106679A (pt
Inventor
Mohammad Salman
Arturo Angel
Vijaya Swaminathan
Original Assignee
Hovione Farmaciencia Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49620233&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT106679(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hovione Farmaciencia Sa filed Critical Hovione Farmaciencia Sa
Priority to PT106679A priority Critical patent/PT106679B/pt
Priority to RU2015122786A priority patent/RU2639591C2/ru
Priority to DK13792728.1T priority patent/DK2925293T3/da
Priority to CA2895395A priority patent/CA2895395C/en
Priority to CN201380068453.1A priority patent/CN104902875B/zh
Priority to EP13792728.1A priority patent/EP2925293B1/en
Priority to PL13792728T priority patent/PL2925293T3/pl
Priority to AU2013350941A priority patent/AU2013350941B2/en
Priority to SG11201504145PA priority patent/SG11201504145PA/en
Priority to BR112015012162-4A priority patent/BR112015012162B1/pt
Priority to US14/074,868 priority patent/US9592246B2/en
Priority to HUE13792728A priority patent/HUE034932T2/en
Priority to MX2015006632A priority patent/MX355174B/es
Priority to ES13792728.1T priority patent/ES2645449T3/es
Priority to KR1020157017068A priority patent/KR102235922B1/ko
Priority to PCT/GB2013/052939 priority patent/WO2014083311A1/en
Priority to NZ708824A priority patent/NZ708824A/en
Priority to JP2015543515A priority patent/JP6444308B2/ja
Priority to NO13792728A priority patent/NO2925293T3/no
Publication of PT106679A publication Critical patent/PT106679A/pt
Publication of PT106679B publication Critical patent/PT106679B/pt
Priority to IL239022A priority patent/IL239022B/en
Priority to ZA2015/04369A priority patent/ZA201504369B/en
Priority to US15/457,809 priority patent/US10213443B2/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/203—Retinoic acids ; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4436—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dispersion Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PT106679A 2012-11-27 2012-11-27 Formulações tópicas de tetraciclinas, sua preparação e usos PT106679B (pt)

Priority Applications (22)

Application Number Priority Date Filing Date Title
PT106679A PT106679B (pt) 2012-11-27 2012-11-27 Formulações tópicas de tetraciclinas, sua preparação e usos
NO13792728A NO2925293T3 (enExample) 2012-11-27 2013-11-08
US14/074,868 US9592246B2 (en) 2012-11-27 2013-11-08 Tetracycline topical formulations, preparation and uses thereof
MX2015006632A MX355174B (es) 2012-11-27 2013-11-08 Formulaciones de uso topico de tetraciclina, preparaciones y usos de las mismas.
CA2895395A CA2895395C (en) 2012-11-27 2013-11-08 Tetracycline topical formulations, preparation and uses thereof
CN201380068453.1A CN104902875B (zh) 2012-11-27 2013-11-08 四环素局部制剂、其制备及用途
EP13792728.1A EP2925293B1 (en) 2012-11-27 2013-11-08 Tetracycline topical formulations, preparation and uses thereof
PL13792728T PL2925293T3 (pl) 2012-11-27 2013-11-08 Formulacje tetracykliny do stosowania miejscowego, ich przygotowanie i zastosowania
AU2013350941A AU2013350941B2 (en) 2012-11-27 2013-11-08 Tetracycline topical formulations, preparation and uses thereof
SG11201504145PA SG11201504145PA (en) 2012-11-27 2013-11-08 Tetracycline topical formulations, preparation and uses thereof
BR112015012162-4A BR112015012162B1 (pt) 2012-11-27 2013-11-08 formulação de suspensão tópica e formulação de suspensão de minociclina tópica para usar no tratamento de acne vulgaris
RU2015122786A RU2639591C2 (ru) 2012-11-27 2013-11-08 Тетрациклиновые композиции для местного применения, их получение и применение
HUE13792728A HUE034932T2 (en) 2012-11-27 2013-11-08 Tetracycline topical formulations, preparation and uses thereof
DK13792728.1T DK2925293T3 (da) 2012-11-27 2013-11-08 Topiske tetracyclinformuleringer, fremstilling og anvendelser deraf
ES13792728.1T ES2645449T3 (es) 2012-11-27 2013-11-08 Formulaciones tópicas de tetraciclina, preparación y usos de las mismas
KR1020157017068A KR102235922B1 (ko) 2012-11-27 2013-11-08 테트라사이클린 국소 제제, 제조방법, 및 이의 용도
PCT/GB2013/052939 WO2014083311A1 (en) 2012-11-27 2013-11-08 Tetracycline topical formulations, preparation and uses thereof
NZ708824A NZ708824A (en) 2012-11-27 2013-11-08 Tetracycline topical formulations, preparation and uses thereof
JP2015543515A JP6444308B2 (ja) 2012-11-27 2013-11-08 テトラサイクリン局所製剤、その調製及び使用
IL239022A IL239022B (en) 2012-11-27 2015-05-26 Tetracycline topical formulations, preparation and uses thereof
ZA2015/04369A ZA201504369B (en) 2012-11-27 2015-06-17 Tetracycline topical formulations, preparation and uses thereof
US15/457,809 US10213443B2 (en) 2012-11-27 2017-03-13 Tetracycline topical formulations, preparation and uses thereof in treating an ocular condition

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PT106679A PT106679B (pt) 2012-11-27 2012-11-27 Formulações tópicas de tetraciclinas, sua preparação e usos

Publications (2)

Publication Number Publication Date
PT106679A PT106679A (pt) 2014-05-27
PT106679B true PT106679B (pt) 2015-03-25

Family

ID=49620233

Family Applications (1)

Application Number Title Priority Date Filing Date
PT106679A PT106679B (pt) 2012-11-27 2012-11-27 Formulações tópicas de tetraciclinas, sua preparação e usos

Country Status (21)

Country Link
US (2) US9592246B2 (enExample)
EP (1) EP2925293B1 (enExample)
JP (1) JP6444308B2 (enExample)
KR (1) KR102235922B1 (enExample)
CN (1) CN104902875B (enExample)
AU (1) AU2013350941B2 (enExample)
BR (1) BR112015012162B1 (enExample)
CA (1) CA2895395C (enExample)
DK (1) DK2925293T3 (enExample)
ES (1) ES2645449T3 (enExample)
HU (1) HUE034932T2 (enExample)
IL (1) IL239022B (enExample)
MX (1) MX355174B (enExample)
NO (1) NO2925293T3 (enExample)
NZ (1) NZ708824A (enExample)
PL (1) PL2925293T3 (enExample)
PT (1) PT106679B (enExample)
RU (1) RU2639591C2 (enExample)
SG (1) SG11201504145PA (enExample)
WO (1) WO2014083311A1 (enExample)
ZA (1) ZA201504369B (enExample)

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FR3064482B1 (fr) * 2017-04-03 2020-11-13 Horus Pharma Composition topique de doxycycline
EP3700504A4 (en) * 2017-10-24 2021-07-28 Glenmark Pharmaceuticals Limited TOPICAL PHARMACEUTICAL COMPOSITION OF ADAPALEN AND MINOCYCLINE
US11421207B2 (en) 2017-11-28 2022-08-23 C-Lecta Gmbh Method for producing trehalose employing a trehalose phosphorylase variant
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