SG11201707784XA - Pharmaceutical tetracycline composition for dermatological use - Google Patents

Pharmaceutical tetracycline composition for dermatological use

Info

Publication number
SG11201707784XA
SG11201707784XA SG11201707784XA SG11201707784XA SG11201707784XA SG 11201707784X A SG11201707784X A SG 11201707784XA SG 11201707784X A SG11201707784X A SG 11201707784XA SG 11201707784X A SG11201707784X A SG 11201707784XA SG 11201707784X A SG11201707784X A SG 11201707784XA
Authority
SG
Singapore
Prior art keywords
dermatological use
tetracycline composition
pharmaceutical
pharmaceutical tetracycline
composition
Prior art date
Application number
SG11201707784XA
Inventor
Xin Chen
Maiko C Hermsmeier
Diana Lac
Douglas W Thomas
Noymi Yam
Akira Yamamoto
Original Assignee
Biopharmx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biopharmx Inc filed Critical Biopharmx Inc
Publication of SG11201707784XA publication Critical patent/SG11201707784XA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/65Tetracyclines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02Local antiseptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
SG11201707784XA 2015-03-23 2016-03-22 Pharmaceutical tetracycline composition for dermatological use SG11201707784XA (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201562137216P 2015-03-23 2015-03-23
US201562245262P 2015-10-22 2015-10-22
US201562251001P 2015-11-04 2015-11-04
US201562266650P 2015-12-13 2015-12-13
US201662279654P 2016-01-15 2016-01-15
US201662304119P 2016-03-04 2016-03-04
PCT/US2016/023646 WO2016154232A2 (en) 2015-03-23 2016-03-22 Pharmaceutical tetracycline composition for dermatological use

Publications (1)

Publication Number Publication Date
SG11201707784XA true SG11201707784XA (en) 2017-10-30

Family

ID=55650759

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201707784XA SG11201707784XA (en) 2015-03-23 2016-03-22 Pharmaceutical tetracycline composition for dermatological use

Country Status (17)

Country Link
US (3) US9918998B2 (en)
EP (1) EP3273940B1 (en)
JP (1) JP6793715B2 (en)
KR (1) KR20170134514A (en)
CN (1) CN107708665B (en)
AU (1) AU2016235237B2 (en)
BR (1) BR112017020358A2 (en)
CA (1) CA2980527A1 (en)
CO (1) CO2017010792A2 (en)
ES (1) ES2846882T3 (en)
IL (1) IL254575A0 (en)
MX (1) MX2017012062A (en)
RU (1) RU2017134566A (en)
SG (1) SG11201707784XA (en)
TW (1) TW201705962A (en)
WO (1) WO2016154232A2 (en)
ZA (2) ZA201706573B (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL152486A0 (en) 2002-10-25 2003-05-29 Meir Eini Alcohol-free cosmetic and pharmaceutical foam carrier
US10117812B2 (en) 2002-10-25 2018-11-06 Foamix Pharmaceuticals Ltd. Foamable composition combining a polar solvent and a hydrophobic carrier
US9265725B2 (en) 2002-10-25 2016-02-23 Foamix Pharmaceuticals Ltd. Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof
US8636982B2 (en) 2007-08-07 2014-01-28 Foamix Ltd. Wax foamable vehicle and pharmaceutical compositions thereof
WO2009090495A2 (en) 2007-12-07 2009-07-23 Foamix Ltd. Oil and liquid silicone foamable carriers and formulations
US20120087872A1 (en) 2009-04-28 2012-04-12 Foamix Ltd. Foamable Vehicles and Pharmaceutical Compositions Comprising Aprotic Polar Solvents and Uses Thereof
WO2011013008A2 (en) 2009-07-29 2011-02-03 Foamix Ltd. Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses
WO2011013009A2 (en) 2009-07-29 2011-02-03 Foamix Ltd. Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses
US10029013B2 (en) 2009-10-02 2018-07-24 Foamix Pharmaceuticals Ltd. Surfactant-free, water-free formable composition and breakable foams and their uses
US9849142B2 (en) 2009-10-02 2017-12-26 Foamix Pharmaceuticals Ltd. Methods for accelerated return of skin integrity and for the treatment of impetigo
ES2846882T3 (en) 2015-03-23 2021-07-30 Biopharmx Inc Pharmaceutical composition of tetracycline for dermatological use
MX2020012139A (en) 2016-09-08 2021-01-29 Vyne Pharmaceuticals Inc Compositions and methods for treating rosacea and acne.
WO2018204711A1 (en) * 2017-05-03 2018-11-08 BioPharmX, Inc. Magnesium chloride composition for dermatological use
JP2021500369A (en) * 2017-10-24 2021-01-07 グレンマーク・ファーマシューティカルズ・リミテッド Topical pharmaceutical compositions of adapalene and minocycline
CA3079789A1 (en) 2017-11-28 2019-06-06 C-Lecta Gmbh Method for producing trehalose employing a trehalose phosphorylase variant
US20190255078A1 (en) * 2018-02-20 2019-08-22 BioPharmX, Inc. Topical compositions with stable solubilized selective retinoids and/or tetracycline-class antibiotics
US11628177B2 (en) * 2020-11-17 2023-04-18 Arcutis Biotherapeutics, Inc. Compositions and methods for deep dermal drug delivery

Family Cites Families (103)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2990331A (en) 1956-11-23 1961-06-27 Pfizer & Co C Stable solutions of salts of tetracyclines for parenteral administration
GB901107A (en) * 1959-06-29 1962-07-11 Pfizer Therapeutic composition and method of preparing same
US3335055A (en) 1961-08-30 1967-08-08 American Cyanamid Co More stable and more soluble tetracycline compositions suitable for parenteral use and method of preparing same
US3389175A (en) 1962-10-04 1968-06-18 American Cyanamid Co Stable tetracycline solutions
US3275513A (en) 1963-05-29 1966-09-27 American Cyanamid Co Stable calcium tetracycline compositions
US3538216A (en) 1964-02-20 1970-11-03 Lab De Rech Physiques S A R L Injectable compositions of a drug suspended in an emulsion
US3957972A (en) 1966-05-31 1976-05-18 Koninklijke Nederlandsche Gist-En Spiritusfabriek N.V. Stable solutions of oxytetracycline suitable for parenteral and peroral administration and process of preparation
US3957980A (en) 1972-10-26 1976-05-18 Pfizer Inc. Doxycycline parenteral compositions
US5108991A (en) 1975-06-19 1992-04-28 Whitby Research, Inc. Vehicle composition containing 1-substituted azacycloalkan-2-ones
US4018889A (en) 1976-01-02 1977-04-19 Pfizer Inc. Oxytetracycline compositions
US4081527A (en) 1976-12-07 1978-03-28 Pfizer Inc. Chlortetracycline compositions
US4126680A (en) 1977-04-27 1978-11-21 Pfizer Inc. Tetracycline antibiotic compositions
CA1163197A (en) 1980-04-10 1984-03-06 Herman Horn Injectable oxytetracycline compositions
US4376118A (en) 1980-10-06 1983-03-08 Miles Laboratories, Inc. Stable nonaqueous solution of tetracycline salt
FR2558372B1 (en) 1984-01-25 1987-08-07 Oreal DRUG COMPOSITION FOR THE TREATMENT OF ACNE
US4701320A (en) 1984-11-29 1987-10-20 Lederle (Japan), Ltd. Composition stably containing minocycline for treating periodontal diseases
IE74244B1 (en) 1985-10-01 1997-07-16 Bimeda Res Dev Ltd A process for preparing an antibiotic composition
JPH01186824A (en) 1988-01-19 1989-07-26 Horiuchiitarou Shoten:Kk Exodermic pharmaceutical composition and method for accelerating percutaneous absorption
US5122519A (en) 1989-06-27 1992-06-16 American Cyanamid Company Stable, cosmetically acceptable topical gel formulation and method of treatment for acne
US5075295A (en) 1989-12-12 1991-12-24 Boehringer Ingelheim Animal Health, Inc. Novel oxytetracycline compositions
US5298238A (en) * 1991-11-07 1994-03-29 Warner-Lambert Company Liquid oral compositions comprising deterpenated and fractionated flavor oils
JPH05306227A (en) 1992-04-27 1993-11-19 Lion Corp Sustained release therapeutic agent for disease in oral cavity
US6077822A (en) 1993-09-14 2000-06-20 Dumex-Alpharma A/S Drug salts
US5538954A (en) 1994-06-24 1996-07-23 A/S Dumex (Dumex Ltd.) Salts of tetracyclines
US6110905A (en) 1994-07-09 2000-08-29 Norbrook Laboratories Limited Long-acting oxytetracycline composition
AU694576B2 (en) 1994-10-21 1998-07-23 Merck & Co., Inc. Combination method for acne treatment
US5807568A (en) 1994-12-27 1998-09-15 Mcneil-Ppc, Inc. Enhanced delivery of topical compositions containing flurbiprofen
US6310053B1 (en) 1995-07-05 2001-10-30 Norbrook Laboratories Limited Long-acting oxytetracycline composition
AUPN814496A0 (en) 1996-02-19 1996-03-14 Monash University Dermal penetration enhancer
US6482839B1 (en) 1997-06-02 2002-11-19 Cellegy Pharmaceuticals, Inc. Pyridine-thiols for treatment of a follicular dermatosis
KR20010013377A (en) 1997-06-04 2001-02-26 데이비드 엠 모이어 Mild, leave-on antimicrobial compositions
US5908838A (en) 1998-02-19 1999-06-01 Medics Pharmaceutical Corporation Method for the treatment of acne
PT1676579E (en) 1998-05-08 2009-03-24 Univ Miami Use of sub-antimicrobial tetracyclines for treating ocular rosacea
US6071541A (en) 1998-07-31 2000-06-06 Murad; Howard Pharmaceutical compositions and methods for managing skin conditions
US20030077301A1 (en) 1999-12-16 2003-04-24 Maibach Howard I. Topical pharmaceutical composition for the treatment of inflammatory dermatoses
JP4653282B2 (en) 2000-05-23 2011-03-16 昭和薬品化工株式会社 Minocycline-containing composition
US6777450B1 (en) 2000-05-26 2004-08-17 Color Access, Inc. Water-thin emulsions with low emulsifier levels
GB0015617D0 (en) 2000-06-26 2000-08-16 Vectura Ltd Improved preparations for dermal delivery of active substances
US20020022040A1 (en) 2000-07-10 2002-02-21 The Proctor & Gamble Company Methods of enhancing delivery of oil-soluble skin care actives
FR2813189B1 (en) 2000-08-31 2003-02-28 Oreal COSMETIC FOAMING CREAM FOR THE TREATMENT OF OILY SKIN
US7211267B2 (en) 2001-04-05 2007-05-01 Collagenex Pharmaceuticals, Inc. Methods of treating acne
DE10121252A1 (en) 2001-04-30 2002-11-07 Christos C Zouboulis Acne treatment
ITRM20010325A1 (en) 2001-06-08 2002-12-09 Univ Napoli Federico Ii PHARMACEUTICAL COMPOSITIONS BASED ON ZEOLITES CONTAINING ZINC AND ERYTHROMYCIN TO BE USED IN ANTI-ACNE THERAPY.
WO2003079984A2 (en) 2002-03-21 2003-10-02 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
CA2483448C (en) 2002-04-25 2011-01-25 William O. Kling Anti-acne compositions and methods of use
US6943197B2 (en) 2002-06-21 2005-09-13 Howard I. Maibach Topical administration of pharmacologically active bases in the treatment of inflammatory dermatoses
EA009024B1 (en) 2002-06-25 2007-10-26 АКРУКС ДиДиЭс ПиТиУай ЭлТиДи Pharmaceutical composition for transdermal delivery of an active agent (variants)
US20040258757A1 (en) 2002-07-16 2004-12-23 Elan Pharma International, Ltd. Liquid dosage compositions of stable nanoparticulate active agents
US20040043946A1 (en) 2002-09-03 2004-03-04 Popp Karl F. Topical formulations for treatment of skin disorders
WO2004032843A2 (en) 2002-10-07 2004-04-22 Orapharma, Inc. Mucoadhesive tetracycline formulations
US8486376B2 (en) 2002-10-25 2013-07-16 Foamix Ltd. Moisturizing foam containing lanolin
CN103040773A (en) 2003-07-25 2013-04-17 沃纳奇尔科特有限责任公司 Doxycycline metal complex in a solid dosage form
US20050239723A1 (en) 2004-04-27 2005-10-27 Amin Avinash N Compositions and methods useful for treatment of acne
AU2005244988C1 (en) 2004-05-21 2012-06-28 President And Fellows Of Harvard College Synthesis of tetracyclines and analogues thereof
US7943600B2 (en) 2004-12-20 2011-05-17 Massachusetts Institute Of Technology Antimicrobial combination therapy
SG158869A1 (en) 2005-01-21 2010-02-26 Warner Chilcott Co Llc A tetracycline metal complex in a solid dosage form
US9314431B2 (en) 2005-02-14 2016-04-19 Transdermal Corp Solubilized benzoyl small molecule
EP1919449A2 (en) 2005-06-07 2008-05-14 Foamix Ltd. Antibiotic kit and composition and uses thereof
US9192615B2 (en) 2008-08-06 2015-11-24 Medicis Pharmaceutical Corporation Method for the treatment of acne and certain dosage forms thereof
US8722650B1 (en) 2005-06-24 2014-05-13 Medicis Pharmaceutical Corporation Extended-release minocycline dosage forms
US20080242642A1 (en) 2007-04-02 2008-10-02 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US8252776B2 (en) 2007-04-02 2012-08-28 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US7919483B2 (en) 2005-06-24 2011-04-05 Medicis Pharmaceutical Corporation Method for the treatment of acne
US7541347B2 (en) 2007-04-02 2009-06-02 Medicis Pharmaceutical Coropration Minocycline oral dosage forms for the treatment of acne
WO2007002761A2 (en) 2005-06-27 2007-01-04 Barrier Therapeutics, Inc. Micogel topical formulations
AR054805A1 (en) 2005-06-29 2007-07-18 Stiefel Laboratories TOPICAL COMPOSITIONS FOR SKIN TREATMENT
WO2007050543A2 (en) 2005-10-24 2007-05-03 Collegium Pharmaceutical, Inc. Topical pharmaceutical foam composition
US20070225301A1 (en) 2006-02-13 2007-09-27 Astion Inflammation Aps Treatment of acne and other diseases
US8388992B2 (en) 2006-03-28 2013-03-05 Georgia-Pacific Consumer Products Lp Anti-microbial hand towel with time-delay chromatic transfer indicator and absorbency rate delay
AU2007235279B2 (en) 2006-04-07 2012-12-06 President And Fellows Of Harvard College Synthesis of tetracyclines and analogues thereof
ES2315123B1 (en) 2006-09-25 2009-12-30 Divasa-Farmavic, S.A. STABLE PHARMACEUTICAL COMPOSITIONS OF TETRACICLINES IN SOLUTION, PROCEDURE FOR OBTAINING AND USES.
CA2892739A1 (en) 2006-12-21 2008-07-03 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for treatment of inflammatory skin disorders
AU2008210557B2 (en) 2007-01-30 2013-08-01 Cypress Pharmaceutical, Inc. Hyaluronate compositions
US20080188445A1 (en) 2007-02-02 2008-08-07 Warner Chilcott Company Inc. Tetracycline compositions for topical administration
US20080188446A1 (en) 2007-02-02 2008-08-07 Warner Chilcott Company Inc. Tetracycline compositions for topical administration
PT103661B (en) 2007-02-23 2010-09-07 Hovione Farmaciencia S A MINOCYCINE PREPARATION PROCESS CRYSTALLINE
WO2008118744A1 (en) 2007-03-23 2008-10-02 Molecular Research Center, Inc. Anti-inflammatory compositions comprising tetracyclines and use thereof in therapy
WO2008121107A1 (en) 2007-04-02 2008-10-09 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US20080248124A1 (en) * 2007-04-03 2008-10-09 Sunstar Kabushiki Kaisha Process for producing pharmaceutical composition
US8974825B2 (en) 2007-07-06 2015-03-10 Lupin Limited Pharmaceutical compositions for gastrointestinal drug delivery
CN101416974A (en) * 2007-10-22 2009-04-29 洛阳普莱柯生物工程有限公司 Preparation method of doxycycline long-acting injection
WO2009090495A2 (en) 2007-12-07 2009-07-23 Foamix Ltd. Oil and liquid silicone foamable carriers and formulations
US20090176719A1 (en) 2008-01-07 2009-07-09 Liolabs Llc Compositions and methods for treating perioral dermatitis
TWI680117B (en) 2008-05-23 2019-12-21 派洛泰克藥物股份有限公司 Tosylate salts and polymorphs of a tetracycline compound
EP2307027A4 (en) 2008-07-11 2012-08-15 Neumedics Tetracycline derivatives with reduced antibiotic activity and neuroprotective benefits
US20120028929A1 (en) 2008-09-19 2012-02-02 Alacrity Bioscience, Inc. Tetracycline stabilizing formulations
US20100292183A1 (en) 2009-05-15 2010-11-18 Shanmugavel Madasamy Tetracycline and uses thereof
PT104644B (en) 2009-06-26 2012-11-06 Hovione Farmaciencia S A Topical formulation containing a tetracycline and a method of treating skin infections using the same
US10029013B2 (en) 2009-10-02 2018-07-24 Foamix Pharmaceuticals Ltd. Surfactant-free, water-free formable composition and breakable foams and their uses
HUE033161T2 (en) 2010-05-12 2017-11-28 Rempex Pharmaceuticals Inc Tetracycline compositions
PT105116B (en) 2010-05-14 2012-10-16 Hovione Farmaciencia S A NEW PARTICLES OF TETRACYCLINE AND PROTEIN AGENT.
RU2603479C2 (en) 2010-05-28 2016-11-27 М.Алфабет 1, ЛЛС. Combined therapy for skin disorders
TW201245116A (en) 2010-08-12 2012-11-16 Tetraphase Pharmaceuticals Inc Tetracycline analogs
CN102008490B (en) * 2010-12-07 2012-06-27 江西新天地药业有限公司 Compound florfenicol injection for animal
CA2861357C (en) 2011-01-19 2022-08-23 Laboratory Skin Care, Inc. Topical minocycline compositions and methods of using the same
US20120190653A1 (en) 2011-01-20 2012-07-26 Dow Pharmaceutical Sciences, Inc. Therapeutic eye drop comprising doxycycline and a stabilizer
AU2012209274A1 (en) 2011-01-24 2013-09-12 Anterios, Inc. Nanoparticle compositions, formulations thereof, and uses therefor
CN102228462B (en) * 2011-05-13 2013-04-03 山东德州神牛药业有限公司 Method for preparing veterinary oxytetracycline-artemisinin injection and clinical application of veterinary oxytetracycline-artemisinin injection
WO2013009586A1 (en) 2011-07-08 2013-01-17 The Research Foundation Of State University Of New York Topical minocycline ointment for suppression of allergic skin responses
PT106679B (en) 2012-11-27 2015-03-25 Hovione Farmaciencia Sa TOPICAL FORMULATIONS OF TETRACYCLINES, THEIR PREPARATION AND USES
WO2015066717A1 (en) * 2013-11-04 2015-05-07 BioPharmX, Inc. Dosage form comprising an active ingredient and a plurality of solid porous microcarriers
IN2013MU03646A (en) 2013-11-20 2015-07-31 Lupin Ltd
ES2846882T3 (en) 2015-03-23 2021-07-30 Biopharmx Inc Pharmaceutical composition of tetracycline for dermatological use

Also Published As

Publication number Publication date
US10391108B2 (en) 2019-08-27
MX2017012062A (en) 2018-06-18
RU2017134566A (en) 2019-04-05
AU2016235237A1 (en) 2017-10-12
CN107708665B (en) 2022-07-22
CO2017010792A2 (en) 2018-01-31
ES2846882T3 (en) 2021-07-30
CN107708665A (en) 2018-02-16
US9918998B2 (en) 2018-03-20
TW201705962A (en) 2017-02-16
EP3273940B1 (en) 2020-12-16
BR112017020358A2 (en) 2018-07-17
KR20170134514A (en) 2017-12-06
EP3273940A2 (en) 2018-01-31
WO2016154232A3 (en) 2016-12-08
AU2016235237B2 (en) 2021-03-11
CA2980527A1 (en) 2016-09-29
ZA201806426B (en) 2019-12-18
JP6793715B2 (en) 2020-12-02
US20180185394A1 (en) 2018-07-05
US10881672B2 (en) 2021-01-05
JP2018509472A (en) 2018-04-05
WO2016154232A2 (en) 2016-09-29
IL254575A0 (en) 2017-11-30
ZA201706573B (en) 2018-12-19
US20160279152A1 (en) 2016-09-29
US20200046739A1 (en) 2020-02-13

Similar Documents

Publication Publication Date Title
ZA201806426B (en) Pharmaceutical tetracycline composition for dermatological use
PL4070788T3 (en) Pharmaceutical formulations
HK1254343A1 (en) Pharmaceutical formulations
GB201506526D0 (en) Medicinal composition
IL263040A (en) Pharmaceutical composition comprising eteplirsen
HK1245653A1 (en) Pharmaceutical formulation
GB201521462D0 (en) Pharmaceutical composition
ZA201707094B (en) Pharmaceutical formulations
IL253177A0 (en) Pharmaceutical formulation
GB201502845D0 (en) Topical pharmaceutical formulation
PL3360547T3 (en) Bactericidal pharmaceutical composition comprising ibuprofen
GB201515310D0 (en) Pharmaceutical composition
GB201520862D0 (en) Pharmaceutical composition
EP3727485C0 (en) Pharmaceutical composition
GB201506755D0 (en) Novel pharmaceutical formulation
GB201511246D0 (en) Pharmaceutical formulation
SG11201608123VA (en) Pharmaceutical composition for external use
HUE057830T2 (en) Pharmaceutical composition comprising famitinib
SG11201608124XA (en) Pharmaceutical composition for external use
SG11201708197QA (en) Pharmaceutical composition for skin
GB201521456D0 (en) Pharmaceutical composition
SG11201608122PA (en) Pharmaceutical composition for external use