PT102450B - Formulacao farmaceutica de libertacao modificada compreendendo amoxicilina e clavulanato de potassio e utilizacao destes compostos no fabrico de um medicamento para o tratamento de infeccoes bacterianas - Google Patents

Formulacao farmaceutica de libertacao modificada compreendendo amoxicilina e clavulanato de potassio e utilizacao destes compostos no fabrico de um medicamento para o tratamento de infeccoes bacterianas

Info

Publication number
PT102450B
PT102450B PT102450A PT10245000A PT102450B PT 102450 B PT102450 B PT 102450B PT 102450 A PT102450 A PT 102450A PT 10245000 A PT10245000 A PT 10245000A PT 102450 B PT102450 B PT 102450B
Authority
PT
Portugal
Prior art keywords
amoxycylin
compounds
manufacture
treatment
bacterial infections
Prior art date
Application number
PT102450A
Other languages
English (en)
Other versions
PT102450A (pt
Inventor
Kevin Storm
Creighton Conley
John Roush
Original Assignee
Beecham Pharm Pte Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27383840&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT102450(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Beecham Pharm Pte Ltd filed Critical Beecham Pharm Pte Ltd
Publication of PT102450A publication Critical patent/PT102450A/pt
Publication of PT102450B publication Critical patent/PT102450B/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/424—Oxazoles condensed with heterocyclic ring systems, e.g. clavulanic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Peptides Or Proteins (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
PT102450A 1999-04-13 2000-04-11 Formulacao farmaceutica de libertacao modificada compreendendo amoxicilina e clavulanato de potassio e utilizacao destes compostos no fabrico de um medicamento para o tratamento de infeccoes bacterianas PT102450B (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12907499P 1999-04-13 1999-04-13
US15072799P 1999-08-25 1999-08-25
US15981399P 1999-10-15 1999-10-15

Publications (2)

Publication Number Publication Date
PT102450A PT102450A (pt) 2001-02-01
PT102450B true PT102450B (pt) 2003-09-30

Family

ID=27383840

Family Applications (2)

Application Number Title Priority Date Filing Date
PT102450A PT102450B (pt) 1999-04-13 2000-04-11 Formulacao farmaceutica de libertacao modificada compreendendo amoxicilina e clavulanato de potassio e utilizacao destes compostos no fabrico de um medicamento para o tratamento de infeccoes bacterianas
PT00303033T PT1044680E (pt) 1999-04-13 2000-04-11 Novo metodo de tratamento utilizando um regime de alta dosagem de amoxicilina e clavulanato de potassio

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT00303033T PT1044680E (pt) 1999-04-13 2000-04-11 Novo metodo de tratamento utilizando um regime de alta dosagem de amoxicilina e clavulanato de potassio

Country Status (45)

Country Link
EP (4) EP1044680B1 (pt)
JP (2) JP4880125B2 (pt)
KR (1) KR100634937B1 (pt)
CN (1) CN100382782C (pt)
AP (1) AP1806A (pt)
AR (1) AR031068A1 (pt)
AT (2) AT4327U1 (pt)
AU (1) AU767177B2 (pt)
BE (2) BE1013309A5 (pt)
BG (1) BG65006B1 (pt)
BR (1) BRPI0009719B8 (pt)
CA (1) CA2366304C (pt)
CO (1) CO5170471A1 (pt)
CZ (1) CZ298801B6 (pt)
DE (3) DE10017883A1 (pt)
DK (3) DK200000602A (pt)
DZ (1) DZ3150A1 (pt)
EA (1) EA004310B1 (pt)
ES (2) ES2202004T3 (pt)
FI (2) FI20000863A (pt)
FR (1) FR2792198A1 (pt)
GB (1) GB2351661B (pt)
GR (1) GR1003560B (pt)
HK (1) HK1032741A1 (pt)
HU (1) HU229097B1 (pt)
IE (1) IE20000271A1 (pt)
IL (2) IL145580A0 (pt)
IT (1) ITMI20000788A1 (pt)
MA (1) MA25352A1 (pt)
MX (1) MXPA01010377A (pt)
MY (1) MY119953A (pt)
NL (2) NL1014915C2 (pt)
NO (1) NO329694B1 (pt)
NZ (1) NZ514575A (pt)
OA (1) OA11926A (pt)
PE (1) PE20010053A1 (pt)
PL (1) PL197448B1 (pt)
PT (2) PT102450B (pt)
RO (1) RO120817B1 (pt)
SE (1) SE0001330L (pt)
SI (2) SI1044680T1 (pt)
SK (1) SK285140B6 (pt)
TR (1) TR200102963T2 (pt)
TW (1) TWI235067B (pt)
WO (1) WO2000061116A2 (pt)

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GB9407386D0 (en) 1994-04-14 1994-06-08 Smithkline Beecham Plc Pharmaceutical formulation
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WO1997009042A1 (en) 1995-09-07 1997-03-13 Smithkline Beecham Corporation Pharmaceutical formulation
SE9802973D0 (sv) 1998-09-03 1998-09-03 Astra Ab Immediate release tablet
US6294199B1 (en) 1999-04-13 2001-09-25 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection comprising administering amoxycillin
US7250176B1 (en) 1999-04-13 2007-07-31 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection
US6878386B1 (en) 1999-04-13 2005-04-12 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection comprising amoxycillin and potassium clavulanate
US6544555B2 (en) 2000-02-24 2003-04-08 Advancis Pharmaceutical Corp. Antibiotic product, use and formulation thereof
US6756057B2 (en) 2000-10-12 2004-06-29 Beecham Pharmaceuticals (Pte) Limited Amoxicillin and potassium clavulanate dosage form
EP1330236A2 (en) * 2000-10-12 2003-07-30 Beecham Pharmaceuticals (Pte) Limited Formulation containing amoxicillin
US20020068078A1 (en) 2000-10-13 2002-06-06 Rudnic Edward M. Antifungal product, use and formulation thereof
US20030035839A1 (en) * 2001-05-15 2003-02-20 Peirce Management, Llc Pharmaceutical composition for both intraoral and oral administration
CA2452871C (en) 2001-07-06 2011-10-04 Endo Pharmaceuticals, Inc. Oxymorphone controlled release formulations
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US6863901B2 (en) 2001-11-30 2005-03-08 Collegium Pharmaceutical, Inc. Pharmaceutical composition for compressed annular tablet with molded triturate tablet for both intraoral and oral administration
US6827946B2 (en) 2001-12-05 2004-12-07 Collegium Pharmaceutical, Inc. Compositions containing both sedative and non-sedative antihistamines
CA2480826C (fr) 2002-04-09 2012-02-07 Flamel Technologies Formulation pharmaceutique orale sous forme de suspension aqueuse de microcapsules permettant la liberation modifiee de principe(s) actif(s)
JP2005528383A (ja) * 2002-04-10 2005-09-22 ミラー，フレッド，エイチ． 多重相・複数コンパートメントカプセルシステム
US20050042289A1 (en) * 2003-04-29 2005-02-24 Yamanouchi Pharma Technologies, Inc. Tablets and methods for modified release of hydrophylic and other active agents
US8062672B2 (en) 2003-08-12 2011-11-22 Shionogi Inc. Antibiotic product, use and formulation thereof
EP1541129A1 (en) * 2003-12-12 2005-06-15 Cimex AG Pharmaceutical effervescent formulation comprising amoxycillin and clavulanic acid
US20070196396A1 (en) * 2004-02-11 2007-08-23 Rubicon Research Private Limited Controlled release pharmaceutical compositions with improved bioavailability
WO2005099672A1 (en) * 2004-04-13 2005-10-27 Ranbaxy Laboratories Limited A modified release pharmaceutical formulation comprising amoxicillin and clavulanate
EP1880716A1 (en) * 2006-07-19 2008-01-23 Sandoz AG Kit of parts comprising an acid labile and an acid resistant pharmaceutically active ingredient
EP2079453A1 (en) * 2006-10-10 2009-07-22 Penwest Pharmaceuticals Co. Robust sustained release formulations
TR200909787A2 (tr) 2009-12-25 2011-07-21 Bi̇lgi̇ç Mahmut Üçüncü kuşak bir sefalosporin ve klavulanik asit içeren farmasötik formülasyonlar.
TR201000687A1 (tr) 2010-01-29 2011-08-22 Bi̇lgi̇ç Mahmut Aktif madde olarak sefiksim ve klavulanik asit içeren efervesan formülasyonlar
TR201000686A1 (tr) 2010-01-29 2011-08-22 B�Lg�� Mahmut Bakteriyel enfeksiyonların tedavisinde suda çözünebilir sefdinir ve klavulanik asit formülasyonları.@
TR201000688A2 (tr) 2010-01-29 2011-08-22 B�Lg�� Mahmut Aktif madde olarak sefaklor ve klavulanik asit içeren efervesan formülasyonlar.
CA2981759C (en) 2015-04-07 2021-10-12 Church & Dwight Co., Inc. Multicomponent gummy compositions with soft core
CN109394718B (zh) * 2018-11-15 2021-04-27 石药集团中诺药业（石家庄）有限公司 一种阿莫西林分散片及其制备方法
CN110051637A (zh) * 2019-05-21 2019-07-26 葵花药业集团北京药物研究院有限公司 阿莫西林克拉维酸钾制剂及其制备方法

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Also Published As

Publication number Publication date
JP2011256180A (ja) 2011-12-22
TR200102963T2 (tr) 2002-02-21
FI4823U1 (fi) 2001-02-16
SK285140B6 (sk) 2006-07-07
FIU20000164U0 (fi) 2000-04-11
BRPI0009719B8 (pt) 2021-05-25
BR0009719A (pt) 2002-01-08
BG104329A (en) 2001-11-30
BG65006B1 (bg) 2006-12-29
AT4327U1 (de) 2001-06-25
IL145580A0 (en) 2002-11-10
PE20010053A1 (es) 2001-03-10
ES2202004T3 (es) 2004-04-01
DK200000602A (da) 2000-10-14
NO329694B1 (no) 2010-12-06
EP1269996A1 (en) 2003-01-02
DK1044680T3 (da) 2003-09-29
DE20006626U1 (de) 2000-10-19
DK200000133U3 (da) 2000-07-28
IL145580A (en) 2007-05-15
AR031068A1 (es) 2003-09-10
WO2000061116A3 (en) 2001-02-01
EP1270005A2 (en) 2003-01-02
SK5342000A3 (en) 2000-11-07
SI1044680T1 (en) 2003-12-31
TWI235067B (en) 2005-07-01
FR2792198A1 (fr) 2000-10-20
RO120817B1 (ro) 2006-08-30
EP1270005A3 (en) 2006-05-17
ATE242629T1 (de) 2003-06-15
HK1032741A1 (en) 2001-08-03
PL339591A1 (en) 2000-10-23
MXPA01010377A (es) 2002-10-23
BE1012733A6 (fr) 2001-02-06
PT1044680E (pt) 2003-10-31
EA004310B1 (ru) 2004-02-26
SE0001330D0 (sv) 2000-04-11
KR100634937B1 (ko) 2006-10-17
ES2190692B1 (es) 2004-11-16
SE0001330L (sv) 2000-10-14
BR0009719B1 (pt) 2014-09-30
KR20020015312A (ko) 2002-02-27
GR1003560B (el) 2001-03-16
DE10017883A1 (de) 2000-10-26
NZ514575A (en) 2004-05-28
NO20001870L (no) 2000-10-16
DE60003255T2 (de) 2004-05-06
EP1269997A1 (en) 2003-01-02
MY119953A (en) 2005-08-30
JP2002541187A (ja) 2002-12-03
PT102450A (pt) 2001-02-01
DZ3150A1 (fr) 2000-10-19
BE1013309A5 (fr) 2001-11-06
NL1014915A1 (nl) 2000-10-16
AU767177B2 (en) 2003-11-06
SI20304A (sl) 2001-02-28
FI20000863A0 (fi) 2000-04-11
PL197448B1 (pl) 2008-03-31
ES2190692A1 (es) 2003-08-01
JP4880125B2 (ja) 2012-02-22
HU229097B1 (en) 2013-07-29
CN100382782C (zh) 2008-04-23
AP1806A (en) 2007-12-14
HU0001471D0 (en) 2000-06-28
GB0008923D0 (en) 2000-05-31
NL1014914C1 (nl) 2000-10-16
ITMI20000788A1 (it) 2001-10-11
DE60003255D1 (de) 2003-07-17
GB2351661A (en) 2001-01-10
HUP0001471A3 (en) 2001-10-29
CN1382040A (zh) 2002-11-27
OA11926A (en) 2006-04-12
AU5702000A (en) 2000-11-14
CZ298801B6 (cs) 2008-02-06
EA200101075A1 (ru) 2002-04-25
IE20000271A1 (en) 2001-04-04
ITMI20000788A0 (it) 2000-04-11
CA2366304A1 (en) 2000-10-19
CZ20001311A3 (cs) 2000-11-15
NO20001870D0 (no) 2000-04-11
FI20000863A (fi) 2000-10-13
EP1044680B1 (en) 2003-06-11
HUP0001471A2 (en) 2001-03-28
MA25352A1 (fr) 2001-12-31
GB2351661B (en) 2001-10-10
CO5170471A1 (es) 2002-06-27
CA2366304C (en) 2004-06-29
AP2001002284A0 (en) 2001-12-31
NL1014915C2 (nl) 2001-02-12
EP1044680A1 (en) 2000-10-18
WO2000061116A2 (en) 2000-10-19

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