ES2190692A1 - Formulacion farmaceutica de amoxicilina y clavulanato de potasio. - Google Patents
Formulacion farmaceutica de amoxicilina y clavulanato de potasio.Info
- Publication number
- ES2190692A1 ES2190692A1 ES200000935A ES200000935A ES2190692A1 ES 2190692 A1 ES2190692 A1 ES 2190692A1 ES 200000935 A ES200000935 A ES 200000935A ES 200000935 A ES200000935 A ES 200000935A ES 2190692 A1 ES2190692 A1 ES 2190692A1
- Authority
- ES
- Spain
- Prior art keywords
- amoxycillin
- treatment
- dosage regimen
- high dosage
- potassium clavulanate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- LSQZJLSUYDQPKJ-NJBDSQKTSA-N amoxicillin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=C(O)C=C1 LSQZJLSUYDQPKJ-NJBDSQKTSA-N 0.000 title abstract 2
- 229960003022 amoxicillin Drugs 0.000 title abstract 2
- LSQZJLSUYDQPKJ-UHFFFAOYSA-N p-Hydroxyampicillin Natural products O=C1N2C(C(O)=O)C(C)(C)SC2C1NC(=O)C(N)C1=CC=C(O)C=C1 LSQZJLSUYDQPKJ-UHFFFAOYSA-N 0.000 title abstract 2
- ABVRVIZBZKUTMK-JSYANWSFSA-M potassium clavulanate Chemical compound [K+].[O-]C(=O)[C@H]1C(=C/CO)/O[C@@H]2CC(=O)N21 ABVRVIZBZKUTMK-JSYANWSFSA-M 0.000 title abstract 2
- 208000035143 Bacterial infection Diseases 0.000 abstract 1
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/424—Oxazoles condensed with heterocyclic ring systems, e.g. clavulanic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
- Peptides Or Proteins (AREA)
Abstract
Formulación farmacéutica de amoxicilina y clavulanato de potasio. La formulación es de liberación modificada y sus ingredientes activos, la amoxicilina y el clavulanato de potasio, están presentes en una relación de 12:1 a 20:1, formulándose todo el clavulanato de potasio y una primera parte de la amoxicilina con excipientes farmacéuticamente aceptables que permiten la liberación inmediata del clavulanato de potasio y la primera parte de la amoxicilina para formar una fase de liberación inmediata, y formulándose una segunda parte de la amoxicilina con excipientes farmacéuticamente aceptables que permiten la liberación lenta de esta segunda parte para formar una fase de liberación lenta. La formulación se presenta preferiblemente como un comprimido de dos capas y es aplicable al tratamiento de infecciones bacterianas.
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12907499P | 1999-04-13 | 1999-04-13 | |
US60/129074 | 1999-04-13 | ||
US15072799P | 1999-08-25 | 1999-08-25 | |
US60/150727 | 1999-08-25 | ||
US15981399P | 1999-10-15 | 1999-10-15 | |
US60/159813 | 1999-10-15 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2190692A1 true ES2190692A1 (es) | 2003-08-01 |
ES2190692B1 ES2190692B1 (es) | 2004-11-16 |
Family
ID=27383840
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES00303033T Expired - Lifetime ES2202004T3 (es) | 1999-04-13 | 2000-04-11 | Novedoso procedimiento de tratamiento usando un fuerte regimen de dosificacion de amoxicilina y clavulanato potasico. |
ES200000935A Withdrawn - After Issue ES2190692B1 (es) | 1999-04-13 | 2000-04-11 | Formulacion farmaceutica de amoxicilina y clavulanato de potasio. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES00303033T Expired - Lifetime ES2202004T3 (es) | 1999-04-13 | 2000-04-11 | Novedoso procedimiento de tratamiento usando un fuerte regimen de dosificacion de amoxicilina y clavulanato potasico. |
Country Status (45)
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9407386D0 (en) | 1994-04-14 | 1994-06-08 | Smithkline Beecham Plc | Pharmaceutical formulation |
GB9408117D0 (en) * | 1994-04-23 | 1994-06-15 | Smithkline Beecham Corp | Pharmaceutical formulations |
BR9610396A (pt) * | 1995-09-07 | 1999-07-06 | Smithkline Beecham Corp | Formulação farmacêutica |
SE9802973D0 (sv) | 1998-09-03 | 1998-09-03 | Astra Ab | Immediate release tablet |
US6878386B1 (en) | 1999-04-13 | 2005-04-12 | Beecham Pharmaceuticals (Pte) Limited | Method of treating a bacterial infection comprising amoxycillin and potassium clavulanate |
US7250176B1 (en) | 1999-04-13 | 2007-07-31 | Beecham Pharmaceuticals (Pte) Limited | Method of treating a bacterial infection |
US6294199B1 (en) | 1999-04-13 | 2001-09-25 | Beecham Pharmaceuticals (Pte) Limited | Method of treating a bacterial infection comprising administering amoxycillin |
US6544555B2 (en) | 2000-02-24 | 2003-04-08 | Advancis Pharmaceutical Corp. | Antibiotic product, use and formulation thereof |
US6756057B2 (en) | 2000-10-12 | 2004-06-29 | Beecham Pharmaceuticals (Pte) Limited | Amoxicillin and potassium clavulanate dosage form |
WO2002030392A2 (en) * | 2000-10-12 | 2002-04-18 | Beecham Pharmaceuticals (Pte) Limited | Formulation containing amoxicillin |
US20020068078A1 (en) | 2000-10-13 | 2002-06-06 | Rudnic Edward M. | Antifungal product, use and formulation thereof |
US20030035839A1 (en) * | 2001-05-15 | 2003-02-20 | Peirce Management, Llc | Pharmaceutical composition for both intraoral and oral administration |
WO2003004030A1 (en) | 2001-07-06 | 2003-01-16 | Endo Pharmaceuticals, Inc. | Oxymorphone controlled release formulations |
GB0117618D0 (en) * | 2001-07-19 | 2001-09-12 | Phoqus Ltd | Pharmaceutical dosage form |
US6863901B2 (en) | 2001-11-30 | 2005-03-08 | Collegium Pharmaceutical, Inc. | Pharmaceutical composition for compressed annular tablet with molded triturate tablet for both intraoral and oral administration |
US6827946B2 (en) | 2001-12-05 | 2004-12-07 | Collegium Pharmaceutical, Inc. | Compositions containing both sedative and non-sedative antihistamines |
EP1492511B3 (fr) | 2002-04-09 | 2012-05-02 | Flamel Technologies | Formulation pharmaceutique orale sous forme de suspension aqueuse de microcapsules permettant la liberation modifiee de principe(s) actif(s) |
EP1499303A4 (en) * | 2002-04-10 | 2007-07-25 | Fred H Miller | MULTIPHASE MULTI-COMPONENT CAPSULE SYSTEM |
US20050042289A1 (en) * | 2003-04-29 | 2005-02-24 | Yamanouchi Pharma Technologies, Inc. | Tablets and methods for modified release of hydrophylic and other active agents |
AU2004264356B2 (en) | 2003-08-12 | 2011-01-27 | Shionogi, Inc. | Antibiotic product, use and formulation thereof |
EP1541129A1 (en) * | 2003-12-12 | 2005-06-15 | Cimex AG | Pharmaceutical effervescent formulation comprising amoxycillin and clavulanic acid |
EP1750717B1 (en) * | 2004-02-11 | 2017-07-19 | Rubicon Research Private Limited | Controlled release pharmaceutical compositions with improved bioavailability |
WO2005099672A1 (en) * | 2004-04-13 | 2005-10-27 | Ranbaxy Laboratories Limited | A modified release pharmaceutical formulation comprising amoxicillin and clavulanate |
EP1880716A1 (en) * | 2006-07-19 | 2008-01-23 | Sandoz AG | Kit of parts comprising an acid labile and an acid resistant pharmaceutically active ingredient |
MX2009003771A (es) * | 2006-10-10 | 2009-07-22 | Penwest Pharmaceuticals Co | Formulaciones robustas de liberacion sostenida. |
TR200909787A2 (tr) | 2009-12-25 | 2011-07-21 | Bi̇lgi̇ç Mahmut | Üçüncü kuşak bir sefalosporin ve klavulanik asit içeren farmasötik formülasyonlar. |
TR201000688A2 (tr) | 2010-01-29 | 2011-08-22 | B�Lg�� Mahmut | Aktif madde olarak sefaklor ve klavulanik asit içeren efervesan formülasyonlar. |
TR201000687A1 (tr) | 2010-01-29 | 2011-08-22 | Bi̇lgi̇ç Mahmut | Aktif madde olarak sefiksim ve klavulanik asit içeren efervesan formülasyonlar |
TR201000686A1 (tr) | 2010-01-29 | 2011-08-22 | B�Lg�� Mahmut | Bakteriyel enfeksiyonların tedavisinde suda çözünebilir sefdinir ve klavulanik asit formülasyonları.@ |
CA2981759C (en) | 2015-04-07 | 2021-10-12 | Church & Dwight Co., Inc. | Multicomponent gummy compositions with soft core |
CN109394718B (zh) * | 2018-11-15 | 2021-04-27 | 石药集团中诺药业(石家庄)有限公司 | 一种阿莫西林分散片及其制备方法 |
CN110051637A (zh) * | 2019-05-21 | 2019-07-26 | 葵花药业集团北京药物研究院有限公司 | 阿莫西林克拉维酸钾制剂及其制备方法 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1995020946A1 (en) * | 1994-02-04 | 1995-08-10 | Smithkline Beecham Plc | Bilayered amoxycillin tablets |
WO1995028148A1 (en) * | 1994-04-14 | 1995-10-26 | Smithkline Beecham Plc | Pharmaceutical formulation |
WO1996004908A1 (en) * | 1994-08-17 | 1996-02-22 | Smithkline Beecham Plc | Pharmaceutical formulation containing amoxycillin and potassium clavulanate |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2964817D1 (en) * | 1978-09-06 | 1983-03-24 | Beecham Group Plc | Pharmaceutical compositions containing two beta-lactam derivatives |
IL58461A0 (en) * | 1978-10-27 | 1980-01-31 | Beecham Group Ltd | Intramammary compositions comprising a clavulanic acid salt |
FR2470599A1 (fr) * | 1979-12-07 | 1981-06-12 | Panoz Donald | Perfectionnements apportes aux procedes de preparation de formes galeniques a action retard et a liberation programmee et formes galeniques de medicaments ainsi obtenus |
GB9007945D0 (en) * | 1990-04-07 | 1990-06-06 | Beecham Group Plc | Pharmaceutical formulation |
GB9109862D0 (en) * | 1991-05-08 | 1991-07-03 | Beecham Lab Sa | Pharmaceutical formulations |
IT1255522B (it) * | 1992-09-24 | 1995-11-09 | Ubaldo Conte | Compressa per impiego terapeutico atta a cedere una o piu' sostanze attive con differenti velocita' |
EP1034784A3 (en) * | 1993-01-22 | 2001-06-27 | Smithkline Beecham Plc | Pharmaceutical formulations containing clavulanic acid and an antibacterial agent |
GB9311030D0 (en) * | 1993-05-28 | 1993-07-14 | Smithkline Beecham Corp | Pharmaceutical formulations |
IL109770A0 (en) * | 1993-05-29 | 1994-11-28 | Smithkline Beecham Corp | Thermal infusion process for preparing controlled release solid dosage forms of medicaments for oral administration and controlled release solid dosage forms of medicaments prepared thereby |
GB9408117D0 (en) * | 1994-04-23 | 1994-06-15 | Smithkline Beecham Corp | Pharmaceutical formulations |
ITMI941169A1 (it) * | 1994-06-06 | 1995-12-06 | Smithkline Beecham Farma | Formulazioni farmaceutiche |
GB9416599D0 (en) * | 1994-08-17 | 1994-10-12 | Smithkline Beecham Plc | Pharmaceutical formulation |
BR9610396A (pt) * | 1995-09-07 | 1999-07-06 | Smithkline Beecham Corp | Formulação farmacêutica |
GB9616536D0 (en) * | 1996-08-06 | 1996-09-25 | Quadrant Holdings Cambridge | Co-amoxiclav dosage form |
PL334976A1 (en) * | 1997-02-14 | 2000-03-27 | Smithkline Beecham Lab | Pharmaceutic preparations containing amoxycyclin and clavulate |
CA2283467A1 (en) * | 1997-03-11 | 1998-09-17 | Almag Al | Process and apparatus for coating metals |
SE9700885D0 (sv) * | 1997-03-12 | 1997-03-12 | Astra Ab | New pharmaceutical formulation |
CA2282531A1 (en) * | 1997-03-25 | 1998-10-01 | Takeda Chemical Industries, Ltd. | Gastrointestinal mucosa-adherent pharmaceutical composition |
JP3746901B2 (ja) * | 1997-10-15 | 2006-02-22 | ユニ・チャーム株式会社 | 開閉自在容器 |
GB9815532D0 (en) * | 1998-07-17 | 1998-09-16 | Lek Pharmaceutical & Cvhemical | Pharmaceutical suspension formulation |
GB9818927D0 (en) * | 1998-08-28 | 1998-10-21 | Smithkline Beecham Plc | Pharmaceutical formulation |
US6225304B1 (en) * | 1999-02-17 | 2001-05-01 | Pharmaceutical Solutions, Inc. | Soluble forms of amoxicillin and treatment of animals |
-
2000
- 2000-04-11 AT AT00303033T patent/ATE242629T1/de active
- 2000-04-11 DE DE60003255T patent/DE60003255T2/de not_active Expired - Lifetime
- 2000-04-11 EP EP02078928A patent/EP1269997A1/en not_active Withdrawn
- 2000-04-11 GR GR20000100122A patent/GR1003560B/el unknown
- 2000-04-11 IL IL14558000A patent/IL145580A0/xx active IP Right Grant
- 2000-04-11 AP APAP/P/2001/002284A patent/AP1806A/en active
- 2000-04-11 CO CO00026419A patent/CO5170471A1/es not_active Application Discontinuation
- 2000-04-11 ES ES00303033T patent/ES2202004T3/es not_active Expired - Lifetime
- 2000-04-11 DZ DZ003150A patent/DZ3150A1/xx active
- 2000-04-11 NL NL1014915A patent/NL1014915C2/nl not_active IP Right Cessation
- 2000-04-11 NZ NZ514575A patent/NZ514575A/en not_active IP Right Cessation
- 2000-04-11 SI SI200000097A patent/SI20304A/sl not_active IP Right Cessation
- 2000-04-11 PL PL339591A patent/PL197448B1/pl unknown
- 2000-04-11 FR FR0004631A patent/FR2792198A1/fr active Pending
- 2000-04-11 PT PT00303033T patent/PT1044680E/pt unknown
- 2000-04-11 BG BG104329A patent/BG65006B1/bg unknown
- 2000-04-11 RO ROA200000399A patent/RO120817B1/ro unknown
- 2000-04-11 AU AU57020/00A patent/AU767177B2/en not_active Expired
- 2000-04-11 WO PCT/IB2000/000992 patent/WO2000061116A2/en active Application Filing
- 2000-04-11 DE DE10017883A patent/DE10017883A1/de not_active Withdrawn
- 2000-04-11 CN CNB008086737A patent/CN100382782C/zh not_active Expired - Lifetime
- 2000-04-11 KR KR1020017012988A patent/KR100634937B1/ko not_active IP Right Cessation
- 2000-04-11 EP EP02078927A patent/EP1270005A3/en not_active Withdrawn
- 2000-04-11 MY MYPI20001509A patent/MY119953A/en unknown
- 2000-04-11 SE SE0001330A patent/SE0001330L/xx not_active Application Discontinuation
- 2000-04-11 CZ CZ20001311A patent/CZ298801B6/cs not_active IP Right Cessation
- 2000-04-11 ES ES200000935A patent/ES2190692B1/es not_active Withdrawn - After Issue
- 2000-04-11 DK DK200000602A patent/DK200000602A/da not_active Application Discontinuation
- 2000-04-11 OA OA1200100257A patent/OA11926A/en unknown
- 2000-04-11 DK DK200000133U patent/DK200000133U3/da not_active IP Right Cessation
- 2000-04-11 EP EP00303033A patent/EP1044680B1/en not_active Expired - Lifetime
- 2000-04-11 MX MXPA01010377A patent/MXPA01010377A/es active IP Right Grant
- 2000-04-11 DK DK00303033T patent/DK1044680T3/da active
- 2000-04-11 SK SK534-2000A patent/SK285140B6/sk not_active IP Right Cessation
- 2000-04-11 HU HU0001471A patent/HU229097B1/hu unknown
- 2000-04-11 EA EA200101075A patent/EA004310B1/ru not_active IP Right Cessation
- 2000-04-11 BE BE2000/0255A patent/BE1013309A5/fr not_active IP Right Cessation
- 2000-04-11 FI FI20000863A patent/FI20000863A/fi unknown
- 2000-04-11 BE BE00/0256A patent/BE1012733A6/fr not_active IP Right Cessation
- 2000-04-11 NO NO20001870A patent/NO329694B1/no not_active IP Right Cessation
- 2000-04-11 AR ARP000101657A patent/AR031068A1/es not_active Application Discontinuation
- 2000-04-11 GB GB0008923A patent/GB2351661B/en not_active Revoked
- 2000-04-11 JP JP2000610449A patent/JP4880125B2/ja not_active Expired - Lifetime
- 2000-04-11 TR TR2001/02963T patent/TR200102963T2/xx unknown
- 2000-04-11 PE PE2000000332A patent/PE20010053A1/es not_active Application Discontinuation
- 2000-04-11 IT IT2000MI000788A patent/ITMI20000788A1/it unknown
- 2000-04-11 SI SI200030183T patent/SI1044680T1/xx unknown
- 2000-04-11 TW TW089106937A patent/TWI235067B/zh not_active IP Right Cessation
- 2000-04-11 NL NL1014914A patent/NL1014914C1/nl not_active IP Right Cessation
- 2000-04-11 IE IE20000271A patent/IE20000271A1/en not_active IP Right Cessation
- 2000-04-11 AT AT0027900U patent/AT4327U1/de not_active IP Right Cessation
- 2000-04-11 FI FI20000164U patent/FI4823U1/fi active
- 2000-04-11 CA CA002366304A patent/CA2366304C/en not_active Expired - Lifetime
- 2000-04-11 PT PT102450A patent/PT102450B/pt active IP Right Grant
- 2000-04-11 DE DE20006626U patent/DE20006626U1/de not_active Expired - Lifetime
- 2000-04-11 EP EP02078926A patent/EP1269996A1/en not_active Withdrawn
- 2000-04-11 BR BRPI0009719A patent/BRPI0009719B8/pt not_active IP Right Cessation
-
2001
- 2001-03-21 HK HK01102048A patent/HK1032741A1/xx not_active IP Right Cessation
- 2001-09-24 IL IL145580A patent/IL145580A/en not_active IP Right Cessation
- 2001-10-12 MA MA26356A patent/MA25352A1/fr unknown
-
2011
- 2011-07-22 JP JP2011161132A patent/JP2011256180A/ja active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1995020946A1 (en) * | 1994-02-04 | 1995-08-10 | Smithkline Beecham Plc | Bilayered amoxycillin tablets |
WO1995028148A1 (en) * | 1994-04-14 | 1995-10-26 | Smithkline Beecham Plc | Pharmaceutical formulation |
WO1996004908A1 (en) * | 1994-08-17 | 1996-02-22 | Smithkline Beecham Plc | Pharmaceutical formulation containing amoxycillin and potassium clavulanate |
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2190692A1 (es) | Formulacion farmaceutica de amoxicilina y clavulanato de potasio. | |
WO2000061115A3 (en) | Pharmaceutical formulation comprising amoxycillin | |
GB9917406D0 (en) | Compounds | |
GB0101577D0 (en) | Compounds | |
GB0031088D0 (en) | Medicaments | |
GB0118238D0 (en) | Medicaments | |
GB0112836D0 (en) | Medicaments | |
MXPA03010790A (es) | Heterociclos biciclicos que contienen nitrogeno para uso como antibacterianos. | |
GB9822440D0 (en) | Medicaments | |
MY115351A (en) | Pharmaceutical formulations | |
NO954996L (no) | Anvendelse av nona- og dekapeptider for fremstilling av et legemiddel for behandling av AIDS | |
HK1016088A1 (en) | Use of ritonavir (abt-538) for improving the pharmacokinetics of drugs metabolized by cytochrome p450 in a method of treating aids | |
CO4560547A1 (es) | Una forma de dosis de azitromicina y un metodo de trata- miento de una infeccion microbiana que involucra la adminis- tracion de azitromicina | |
EP1663959A4 (en) | NEW AMIDINE COMPOUNDS FOR THE TREATMENT OF MICROBIAL INFECTIONS | |
AU2861389A (en) | Disubstituted pyridines | |
WO2005042699A3 (en) | Modified polypeptides with therapeutic activity and methods of use | |
ECSP003432A (es) | Nuevo metodo de tratamiento | |
AU2002236587A1 (en) | Compositions for adhesion prevention | |
UY26104A1 (es) | Nuevo metodo de tratamiento. | |
AU2002360218A1 (en) | A METHOD OF TREATING BACTERIAL INFECTIONS USING GEMIFLOXACIN OR A SALT THEREOF AND A Beta -LACTAM ANTIBIOTIC | |
SE9602145D0 (sv) | New improved formulation for treatment of thromboembolism | |
UA49675A (uk) | Спосіб лікування орнітозної пневмонії | |
AU2003298203A1 (en) | Medicaments containing substituted 2,5-diaminomethyl-1h-pyrroles | |
UA40992A (uk) | Спосіб лікування хворих на позагоспітальну пневмонію з тяжким перебігом | |
UA40215A (uk) | Спосіб лікування дітей, хворих на пневмонію |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
EC2A | Search report published |
Date of ref document: 20030801 Kind code of ref document: A1 |
|
FG2A | Definitive protection |
Ref document number: 2190692B1 Country of ref document: ES |
|
FA2A | Application withdrawn |
Effective date: 20050401 |