PL72695B1 - 1-substituted-4-aryl-2(1h)-quinazolinones and their preparation [us3723432a] - Google Patents

1-substituted-4-aryl-2(1h)-quinazolinones and their preparation [us3723432a] Download PDF

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Publication number
PL72695B1
PL72695B1 PL1969136872A PL13687269A PL72695B1 PL 72695 B1 PL72695 B1 PL 72695B1 PL 1969136872 A PL1969136872 A PL 1969136872A PL 13687269 A PL13687269 A PL 13687269A PL 72695 B1 PL72695 B1 PL 72695B1
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Poland
Prior art keywords
compounds
general formula
group
reacted
preparation
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PL1969136872A
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English (en)
Polish (pl)
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/073Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
PL1969136872A 1968-11-12 1969-11-12 1-substituted-4-aryl-2(1h)-quinazolinones and their preparation [us3723432a] PL72695B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US00775201A US3723432A (en) 1968-11-12 1968-11-12 1-substituted-4-aryl-2(1h)-quinazolinones and their preparation

Publications (1)

Publication Number Publication Date
PL72695B1 true PL72695B1 (en) 1974-08-30

Family

ID=25103642

Family Applications (1)

Application Number Title Priority Date Filing Date
PL1969136872A PL72695B1 (en) 1968-11-12 1969-11-12 1-substituted-4-aryl-2(1h)-quinazolinones and their preparation [us3723432a]

Country Status (19)

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US (2) US3723432A (enEXAMPLES)
AT (4) AT319949B (enEXAMPLES)
BE (1) BE741529A (enEXAMPLES)
BG (10) BG16042A3 (enEXAMPLES)
BR (1) BR6914095D0 (enEXAMPLES)
CH (1) CH521972A (enEXAMPLES)
DE (1) DE1956384C3 (enEXAMPLES)
DK (1) DK129347B (enEXAMPLES)
ES (1) ES373377A1 (enEXAMPLES)
FR (1) FR2024830B1 (enEXAMPLES)
GB (1) GB1282612A (enEXAMPLES)
IE (1) IE33933B1 (enEXAMPLES)
IL (1) IL33348A (enEXAMPLES)
NL (1) NL6916514A (enEXAMPLES)
NO (1) NO124032B (enEXAMPLES)
OA (1) OA03829A (enEXAMPLES)
PL (1) PL72695B1 (enEXAMPLES)
SE (2) SE376917B (enEXAMPLES)
ZA (1) ZA697910B (enEXAMPLES)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3923803A (en) * 1968-07-18 1975-12-02 Sumitomo Chemical Co 2(1H)-Quinozalinones and process therefor
US3642791A (en) * 1969-08-13 1972-02-15 Sandoz Ag Morpholino-1-substituted-2(1h)-quinazolinones
US4208343A (en) * 1970-10-30 1980-06-17 Westinghouse Electric Corp. 2,4 Diamino benzonitrile
BE785937A (fr) * 1971-07-08 1973-01-08 Sandoz Sa Nouveaux derives de la quinazoline, leur preparation et leur application comme medicaments
US3937705A (en) * 1972-03-09 1976-02-10 Sandoz, Inc. 1-isopropyl-7-methyl-4-(p-fluorophenyl)-2(1h)-quinazolinone
US4064246A (en) * 1976-10-12 1977-12-20 Sandoz, Inc. Hydroxymethyl-substituted-2(1H)-quinazolinones
US4071516A (en) * 1976-08-20 1978-01-31 Sandoz, Inc. 4-(Acyloxyphenyl)-quinazolin-2(1H)-ones
US4160092A (en) * 1977-06-16 1979-07-03 E. I. Du Pont De Nemours And Company Quinazolinone oxides and their use as intermediates for pharmaceutical agents
US4224328A (en) * 1979-04-11 1980-09-23 Sandoz, Inc. Methods with 1-substituted-4-aryl-quinazolin-2(1H)-ones and thiones and pyrido[2,3-d]pyrimidin-2-ones as platelet aggregation inhibitors
CH645362A5 (de) * 1979-07-05 1984-09-28 Sandoz Ag Verfahren zur herstellung von 4-phenyl-2(1h)-chinazolinonen.
FR2676042B1 (fr) * 1991-05-02 1993-07-23 Commissariat Energie Atomique Procede de preparation d'un borohydrure de metal alcalin tel que le borohydrure de lithium.
US6545004B1 (en) * 1999-10-27 2003-04-08 Cytokinetics, Inc. Methods and compositions utilizing quinazolinones
US7230000B1 (en) 1999-10-27 2007-06-12 Cytokinetics, Incorporated Methods and compositions utilizing quinazolinones
AR038658A1 (es) * 2001-06-15 2005-01-26 Novartis Ag Derivados de 4-aril-2(1h) quinazolinona y 4-aril-quinazolina 2-sustituidas, un proceso para su preparacion, composiciones farmaceuticas y el uso de dichos derivados para la preparacion de un medicamento
AU2002346471A1 (en) * 2001-11-20 2003-06-10 Cytokinetics, Inc. Process for the racemization of chiral quinazolinones
CA2475879A1 (en) * 2002-02-15 2003-08-28 Cytokinetics, Inc. Synthesis of quinazolinones
WO2003097053A1 (en) 2002-05-09 2003-11-27 Cytokinetics, Inc. Compounds, compositions, and methods
US7166595B2 (en) * 2002-05-09 2007-01-23 Cytokinetics, Inc. Compounds, methods and compositions
EP1513820A4 (en) * 2002-05-23 2006-09-13 Cytokinetics Inc COMPOUNDS, COMPOSITIONS AND METHODS
AU2003236527A1 (en) * 2002-06-14 2003-12-31 Cytokinetics, Inc. Compounds, compositions, and methods
US7211580B2 (en) * 2002-07-23 2007-05-01 Cytokinetics, Incorporated Compounds, compositions, and methods
AU2003262747A1 (en) * 2002-08-21 2004-03-11 Cytokinetics, Inc. Compounds, compositions, and methods
EP1558083A4 (en) * 2002-09-30 2008-04-16 Cytokinetics Inc COMPOUNDS, COMPOSITIONS AND METHODS
GB0230015D0 (en) * 2002-12-23 2003-01-29 Novartis Ag Organic compounds
US7439241B2 (en) 2003-05-27 2008-10-21 Galderma Laboratories, Inc. Compounds, formulations, and methods for treating or preventing rosacea
US8410102B2 (en) 2003-05-27 2013-04-02 Galderma Laboratories Inc. Methods and compositions for treating or preventing erythema
JP2007510652A (ja) * 2003-11-03 2007-04-26 サイトキネティクス・インコーポレーテッド ピリミジン−4−オン化合物、組成物、および方法
WO2005046588A2 (en) * 2003-11-07 2005-05-26 Cytokinetics, Inc. Compounds, compositions, and methods
US7439254B2 (en) * 2003-12-08 2008-10-21 Cytokinetics, Inc. Compounds, compositions, and methods
EP2173724B1 (en) * 2007-06-22 2012-12-05 ArQule, Inc. Quinazolinone compounds and methods of use thereof
US8058469B2 (en) * 2008-11-03 2011-11-15 Sabic Innovative Plastics Ip B.V. Method for making carbamates, ureas and isocyanates
EP2329849B1 (en) 2009-11-18 2015-04-29 Galderma Research & Development Combination of alpha-2 adrenergic receptor agonist and non-steroidal anti-inflammatory agent for treating or preventing an inflammatory skin disorder
US8394800B2 (en) * 2009-11-19 2013-03-12 Galderma Laboratories, L.P. Method for treating psoriasis
WO2011117378A2 (en) 2010-03-26 2011-09-29 Galderma Research & Development Improved methods and compositions for safe and effective treatment of telangiectasia
KR101707704B1 (ko) 2010-03-26 2017-02-16 갈데르마 리써어치 앤드 디벨로프먼트 홍반의 유효하고 안전한 치료를 위한 개선된 방법 및 조성물
BR112013009578B1 (pt) 2010-10-21 2020-10-20 Galderma S.A. composição tópica em gel e uso de uma composição tópica em gel
US8053427B1 (en) 2010-10-21 2011-11-08 Galderma R&D SNC Brimonidine gel composition

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3452041A (en) * 1965-05-19 1969-06-24 American Home Prod Hydantoin compounds and methods of preparation

Also Published As

Publication number Publication date
BG16042A3 (bg) 1972-05-20
IL33348A0 (en) 1970-01-29
DK129347B (da) 1974-09-30
BG15573A3 (bg) 1976-06-26
AT310169B (de) 1973-09-25
BG16038A3 (bg) 1972-05-20
BG16040A3 (bg) 1972-05-20
BG16039A3 (bg) 1972-05-20
USB313531I5 (enEXAMPLES) 1975-01-28
IE33933L (en) 1970-05-12
FR2024830B1 (enEXAMPLES) 1973-07-13
ZA697910B (en) 1971-07-28
SE374920B (enEXAMPLES) 1975-03-24
DK129347C (enEXAMPLES) 1975-02-17
OA03829A (fr) 1971-12-24
IL33348A (en) 1973-04-30
BE741529A (enEXAMPLES) 1970-05-11
BG16036A3 (bg) 1972-05-20
US3925548A (en) 1975-12-09
SE376917B (enEXAMPLES) 1975-06-16
BR6914095D0 (pt) 1973-02-13
BG16037A3 (bg) 1972-05-20
ES373377A1 (es) 1972-05-16
US3723432A (en) 1973-03-27
BG16041A3 (bg) 1972-05-20
FR2024830A1 (enEXAMPLES) 1970-09-04
AT319949B (de) 1975-01-10
IE33933B1 (en) 1974-12-11
AT310176B (de) 1973-09-25
SU366612A3 (enEXAMPLES) 1973-01-16
DE1956384C3 (de) 1980-10-09
AT319950B (de) 1975-01-10
DE1956384A1 (de) 1970-06-11
GB1282612A (en) 1972-07-19
NL6916514A (enEXAMPLES) 1970-05-14
NO124032B (enEXAMPLES) 1972-02-21
BG16043A3 (bg) 1972-05-20
DE1956384B2 (de) 1980-02-07
CH521972A (de) 1972-04-30
BG16188A3 (bg) 1972-07-20

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