BE741529A - - Google Patents

Info

Publication number
BE741529A
BE741529A BE741529A BE741529A BE741529A BE 741529 A BE741529 A BE 741529A BE 741529 A BE741529 A BE 741529A BE 741529 A BE741529 A BE 741529A BE 741529 A BE741529 A BE 741529A
Authority
BE
Belgium
Application number
BE741529A
Inventor
H Ott
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of BE741529A publication Critical patent/BE741529A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
BE741529A 1968-11-12 1969-11-10 BE741529A (xx)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US00775201A US3723432A (en) 1968-11-12 1968-11-12 1-substituted-4-aryl-2(1h)-quinazolinones and their preparation

Publications (1)

Publication Number Publication Date
BE741529A true BE741529A (xx) 1970-05-11

Family

ID=25103642

Family Applications (1)

Application Number Title Priority Date Filing Date
BE741529A BE741529A (xx) 1968-11-12 1969-11-10

Country Status (19)

Country Link
US (2) US3723432A (xx)
AT (4) AT310176B (xx)
BE (1) BE741529A (xx)
BG (10) BG16042A3 (xx)
BR (1) BR6914095D0 (xx)
CH (1) CH521972A (xx)
DE (1) DE1956384C3 (xx)
DK (1) DK129347B (xx)
ES (1) ES373377A1 (xx)
FR (1) FR2024830B1 (xx)
GB (1) GB1282612A (xx)
IE (1) IE33933B1 (xx)
IL (1) IL33348A (xx)
NL (1) NL6916514A (xx)
NO (1) NO124032B (xx)
OA (1) OA03829A (xx)
PL (1) PL72695B1 (xx)
SE (2) SE376917B (xx)
ZA (1) ZA697910B (xx)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3923803A (en) * 1968-07-18 1975-12-02 Sumitomo Chemical Co 2(1H)-Quinozalinones and process therefor
US3642791A (en) * 1969-08-13 1972-02-15 Sandoz Ag Morpholino-1-substituted-2(1h)-quinazolinones
US4208343A (en) * 1970-10-30 1980-06-17 Westinghouse Electric Corp. 2,4 Diamino benzonitrile
BE785937A (fr) * 1971-07-08 1973-01-08 Sandoz Sa Nouveaux derives de la quinazoline, leur preparation et leur application comme medicaments
US3937705A (en) * 1972-03-09 1976-02-10 Sandoz, Inc. 1-isopropyl-7-methyl-4-(p-fluorophenyl)-2(1h)-quinazolinone
US4064246A (en) * 1976-10-12 1977-12-20 Sandoz, Inc. Hydroxymethyl-substituted-2(1H)-quinazolinones
US4071516A (en) * 1976-08-20 1978-01-31 Sandoz, Inc. 4-(Acyloxyphenyl)-quinazolin-2(1H)-ones
US4160092A (en) * 1977-06-16 1979-07-03 E. I. Du Pont De Nemours And Company Quinazolinone oxides and their use as intermediates for pharmaceutical agents
US4224328A (en) * 1979-04-11 1980-09-23 Sandoz, Inc. Methods with 1-substituted-4-aryl-quinazolin-2(1H)-ones and thiones and pyrido[2,3-d]pyrimidin-2-ones as platelet aggregation inhibitors
CH645362A5 (de) * 1979-07-05 1984-09-28 Sandoz Ag Verfahren zur herstellung von 4-phenyl-2(1h)-chinazolinonen.
FR2676042B1 (fr) * 1991-05-02 1993-07-23 Commissariat Energie Atomique Procede de preparation d'un borohydrure de metal alcalin tel que le borohydrure de lithium.
US6545004B1 (en) 1999-10-27 2003-04-08 Cytokinetics, Inc. Methods and compositions utilizing quinazolinones
US7230000B1 (en) * 1999-10-27 2007-06-12 Cytokinetics, Incorporated Methods and compositions utilizing quinazolinones
AR038658A1 (es) * 2001-06-15 2005-01-26 Novartis Ag Derivados de 4-aril-2(1h) quinazolinona y 4-aril-quinazolina 2-sustituidas, un proceso para su preparacion, composiciones farmaceuticas y el uso de dichos derivados para la preparacion de un medicamento
AU2002346471A1 (en) * 2001-11-20 2003-06-10 Cytokinetics, Inc. Process for the racemization of chiral quinazolinones
AU2003213092A1 (en) * 2002-02-15 2003-09-09 Smithkline Beecham Corporation Syntheses of quinazolinones
JP2005530785A (ja) * 2002-05-09 2005-10-13 サイトキネティクス・インコーポレーテッド 化合物、組成物、及び方法
BR0309892A2 (pt) * 2002-05-09 2011-04-05 Cytokinetics Inc composto, composição, métodos para modular a atividade da cinesina de ksp, para inibir a ksp, e para o tratamento de uma doença proliferativa celular, e, uso de um composto
US7038048B2 (en) * 2002-05-23 2006-05-02 Cytokinetics, Inc. 3H-pyridopyrimidin-4-one compounds, compositions, and methods of their use
EP1556357A4 (en) * 2002-06-14 2006-09-13 Cytokinetics Inc COMPOUNDS, COMPOSITIONS AND METHODS
AU2003256805A1 (en) * 2002-07-23 2004-02-09 Cytokinetics, Inc. Compounds compositions and methods
US20040048853A1 (en) * 2002-08-21 2004-03-11 Gustave Bergnes Compounds, compositions, and methods
EP1558083A4 (en) * 2002-09-30 2008-04-16 Cytokinetics Inc COMPOUNDS, COMPOSITIONS AND METHODS
GB0230015D0 (en) * 2002-12-23 2003-01-29 Novartis Ag Organic compounds
US8410102B2 (en) 2003-05-27 2013-04-02 Galderma Laboratories Inc. Methods and compositions for treating or preventing erythema
US7439241B2 (en) 2003-05-27 2008-10-21 Galderma Laboratories, Inc. Compounds, formulations, and methods for treating or preventing rosacea
JP2007510652A (ja) * 2003-11-03 2007-04-26 サイトキネティクス・インコーポレーテッド ピリミジン−４−オン化合物、組成物、および方法
EP1680420A4 (en) * 2003-11-07 2008-09-24 Cytokinetics Inc COMPOUNDS, COMPOSITIONS AND METHODS
JP2007513154A (ja) * 2003-12-08 2007-05-24 サイトキネティクス・インコーポレーテッド 化合物、組成物及び方法
JP2010530885A (ja) * 2007-06-22 2010-09-16 アークル インコーポレイテッド キナゾリノン化合物およびその使用方法
US8058469B2 (en) * 2008-11-03 2011-11-15 Sabic Innovative Plastics Ip B.V. Method for making carbamates, ureas and isocyanates
EP2329849B1 (en) 2009-11-18 2015-04-29 Galderma Research & Development Combination of alpha-2 adrenergic receptor agonist and non-steroidal anti-inflammatory agent for treating or preventing an inflammatory skin disorder
US8394800B2 (en) 2009-11-19 2013-03-12 Galderma Laboratories, L.P. Method for treating psoriasis
BR112012024289A2 (pt) 2010-03-26 2017-07-18 Galderma Res & Dev "método para fornecer um tratamento seguro e efetivo do eritema e composição de gel tópica"
KR20130010122A (ko) 2010-03-26 2013-01-25 갈데르마 리써어치 앤드 디벨로프먼트 모세혈관 확장증의 안전하고 유효한 치료를 위한 개선된 방법 및 조성물
ES2498217T5 (es) 2010-10-21 2018-03-19 Galderma S.A. Composición en forma de gel basada en brimonidina
US8053427B1 (en) 2010-10-21 2011-11-08 Galderma R&D SNC Brimonidine gel composition

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3452041A (en) * 1965-05-19 1969-06-24 American Home Prod Hydantoin compounds and methods of preparation

Also Published As

Publication number Publication date
SE376917B (xx) 1975-06-16
IL33348A0 (en) 1970-01-29
BG16039A3 (bg) 1972-05-20
USB313531I5 (xx) 1975-01-28
CH521972A (de) 1972-04-30
BG16038A3 (bg) 1972-05-20
OA03829A (fr) 1971-12-24
FR2024830A1 (xx) 1970-09-04
NL6916514A (xx) 1970-05-14
BG16037A3 (bg) 1972-05-20
SU366612A3 (xx) 1973-01-16
AT319950B (de) 1975-01-10
BG16036A3 (bg) 1972-05-20
NO124032B (xx) 1972-02-21
PL72695B1 (en) 1974-08-30
IE33933L (en) 1970-05-12
DK129347C (xx) 1975-02-17
IE33933B1 (en) 1974-12-11
DK129347B (da) 1974-09-30
ES373377A1 (es) 1972-05-16
IL33348A (en) 1973-04-30
BG16041A3 (bg) 1972-05-20
FR2024830B1 (xx) 1973-07-13
DE1956384C3 (de) 1980-10-09
DE1956384A1 (de) 1970-06-11
AT319949B (de) 1975-01-10
GB1282612A (en) 1972-07-19
DE1956384B2 (de) 1980-02-07
AT310176B (de) 1973-09-25
BG16188A3 (bg) 1972-07-20
BG15573A3 (bg) 1976-06-26
SE374920B (xx) 1975-03-24
BG16043A3 (bg) 1972-05-20
BG16042A3 (bg) 1972-05-20
BG16040A3 (bg) 1972-05-20
US3723432A (en) 1973-03-27
ZA697910B (en) 1971-07-28
AT310169B (de) 1973-09-25
BR6914095D0 (pt) 1973-02-13
US3925548A (en) 1975-12-09

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