DK129347C - - Google Patents

Info

Publication number
DK129347C
DK129347C DK597169A DK597169A DK129347C DK 129347 C DK129347 C DK 129347C DK 597169 A DK597169 A DK 597169A DK 597169 A DK597169 A DK 597169A DK 129347 C DK129347 C DK 129347C
Authority
DK
Denmark
Application number
DK597169A
Other languages
Danish (da)
Other versions
DK129347B (da
Inventor
H Ott
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Priority to DK586173A priority Critical patent/DK130739B/da
Priority to DK585973A priority patent/DK130738B/da
Publication of DK129347B publication Critical patent/DK129347B/da
Application granted granted Critical
Publication of DK129347C publication Critical patent/DK129347C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/073Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DK597169AA 1968-11-12 1969-11-11 Analogifremgangsmåde til fremstilling af 4-phenyl-2(1H)-quinazolinoner eller syreadditionssalte heraf. DK129347B (da)

Priority Applications (2)

Application Number Priority Date Filing Date Title
DK586173A DK130739B (da) 1968-11-12 1973-10-30 Analogifremgangsmåde til fremstilling af aminosubstituerede 1-alkyl-4-phenyl-2(1H)-quinazolinoner eller syreadditionssalte heraf.
DK585973A DK130738B (da) 1968-11-12 1973-10-30 Analogifremgangsmåde til fremstilling af nitro- eller aminosubstituerede 1-alkyl-4-phenyl-2(1H)-quinazolinoner eller syreadditionssalte heraf.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US00775201A US3723432A (en) 1968-11-12 1968-11-12 1-substituted-4-aryl-2(1h)-quinazolinones and their preparation

Publications (2)

Publication Number Publication Date
DK129347B DK129347B (da) 1974-09-30
DK129347C true DK129347C (xx) 1975-02-17

Family

ID=25103642

Family Applications (1)

Application Number Title Priority Date Filing Date
DK597169AA DK129347B (da) 1968-11-12 1969-11-11 Analogifremgangsmåde til fremstilling af 4-phenyl-2(1H)-quinazolinoner eller syreadditionssalte heraf.

Country Status (19)

Country Link
US (2) US3723432A (xx)
AT (4) AT310169B (xx)
BE (1) BE741529A (xx)
BG (10) BG16042A3 (xx)
BR (1) BR6914095D0 (xx)
CH (1) CH521972A (xx)
DE (1) DE1956384C3 (xx)
DK (1) DK129347B (xx)
ES (1) ES373377A1 (xx)
FR (1) FR2024830B1 (xx)
GB (1) GB1282612A (xx)
IE (1) IE33933B1 (xx)
IL (1) IL33348A (xx)
NL (1) NL6916514A (xx)
NO (1) NO124032B (xx)
OA (1) OA03829A (xx)
PL (1) PL72695B1 (xx)
SE (2) SE376917B (xx)
ZA (1) ZA697910B (xx)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3923803A (en) * 1968-07-18 1975-12-02 Sumitomo Chemical Co 2(1H)-Quinozalinones and process therefor
US3642791A (en) * 1969-08-13 1972-02-15 Sandoz Ag Morpholino-1-substituted-2(1h)-quinazolinones
US4208343A (en) * 1970-10-30 1980-06-17 Westinghouse Electric Corp. 2,4 Diamino benzonitrile
BE785937A (fr) * 1971-07-08 1973-01-08 Sandoz Sa Nouveaux derives de la quinazoline, leur preparation et leur application comme medicaments
US3937705A (en) * 1972-03-09 1976-02-10 Sandoz, Inc. 1-isopropyl-7-methyl-4-(p-fluorophenyl)-2(1h)-quinazolinone
US4071516A (en) * 1976-08-20 1978-01-31 Sandoz, Inc. 4-(Acyloxyphenyl)-quinazolin-2(1H)-ones
US4064246A (en) * 1976-10-12 1977-12-20 Sandoz, Inc. Hydroxymethyl-substituted-2(1H)-quinazolinones
US4160092A (en) * 1977-06-16 1979-07-03 E. I. Du Pont De Nemours And Company Quinazolinone oxides and their use as intermediates for pharmaceutical agents
US4224328A (en) * 1979-04-11 1980-09-23 Sandoz, Inc. Methods with 1-substituted-4-aryl-quinazolin-2(1H)-ones and thiones and pyrido[2,3-d]pyrimidin-2-ones as platelet aggregation inhibitors
CH645362A5 (de) * 1979-07-05 1984-09-28 Sandoz Ag Verfahren zur herstellung von 4-phenyl-2(1h)-chinazolinonen.
FR2676042B1 (fr) * 1991-05-02 1993-07-23 Commissariat Energie Atomique Procede de preparation d'un borohydrure de metal alcalin tel que le borohydrure de lithium.
US6545004B1 (en) 1999-10-27 2003-04-08 Cytokinetics, Inc. Methods and compositions utilizing quinazolinones
US7230000B1 (en) 1999-10-27 2007-06-12 Cytokinetics, Incorporated Methods and compositions utilizing quinazolinones
AR038658A1 (es) 2001-06-15 2005-01-26 Novartis Ag Derivados de 4-aril-2(1h) quinazolinona y 4-aril-quinazolina 2-sustituidas, un proceso para su preparacion, composiciones farmaceuticas y el uso de dichos derivados para la preparacion de un medicamento
AU2002346471A1 (en) * 2001-11-20 2003-06-10 Cytokinetics, Inc. Process for the racemization of chiral quinazolinones
WO2003070701A2 (en) * 2002-02-15 2003-08-28 Cytokinetics, Inc. Syntheses of quinazolinones
WO2003097053A1 (en) 2002-05-09 2003-11-27 Cytokinetics, Inc. Compounds, compositions, and methods
CN100491358C (zh) * 2002-05-09 2009-05-27 赛特凯恩蒂克公司 嘧啶酮类化合物、组合物及方法
US7038048B2 (en) * 2002-05-23 2006-05-02 Cytokinetics, Inc. 3H-pyridopyrimidin-4-one compounds, compositions, and methods of their use
WO2003106426A1 (en) * 2002-06-14 2003-12-24 Cytokinetics, Inc. Compounds, compositions, and methods
JP2006501201A (ja) * 2002-07-23 2006-01-12 サイトキネティクス・インコーポレーテッド 化合物、組成物および方法
US20040048853A1 (en) * 2002-08-21 2004-03-11 Gustave Bergnes Compounds, compositions, and methods
WO2004034972A2 (en) * 2002-09-30 2004-04-29 Cytokinetics, Inc. Compounds, compositions, and methods
GB0230015D0 (en) * 2002-12-23 2003-01-29 Novartis Ag Organic compounds
US7439241B2 (en) * 2003-05-27 2008-10-21 Galderma Laboratories, Inc. Compounds, formulations, and methods for treating or preventing rosacea
US8410102B2 (en) 2003-05-27 2013-04-02 Galderma Laboratories Inc. Methods and compositions for treating or preventing erythema
EP1682534A2 (en) * 2003-11-03 2006-07-26 Cytokinetics, Inc. Pyrimidin-4-one compounds, compositions, and methods
WO2005046588A2 (en) * 2003-11-07 2005-05-26 Cytokinetics, Inc. Compounds, compositions, and methods
WO2005061460A1 (en) * 2003-12-08 2005-07-07 Cytokinetics, Inc. Compounds, compositions, and methods
JP2010530885A (ja) * 2007-06-22 2010-09-16 アークル インコーポレイテッド キナゾリノン化合物およびその使用方法
US8058469B2 (en) * 2008-11-03 2011-11-15 Sabic Innovative Plastics Ip B.V. Method for making carbamates, ureas and isocyanates
EP2329849B1 (en) 2009-11-18 2015-04-29 Galderma Research & Development Combination of alpha-2 adrenergic receptor agonist and non-steroidal anti-inflammatory agent for treating or preventing an inflammatory skin disorder
US8394800B2 (en) 2009-11-19 2013-03-12 Galderma Laboratories, L.P. Method for treating psoriasis
JP5747392B2 (ja) 2010-03-26 2015-07-15 ガルデルマ・リサーチ・アンド・デヴェロップメント 毛細血管拡張症の安全かつ有効な治療のための改善された方法および組成物
HUE033143T2 (en) 2010-03-26 2017-11-28 Galderma Res & Dev Preparations containing brimonidine for the treatment of erythema
US8053427B1 (en) 2010-10-21 2011-11-08 Galderma R&D SNC Brimonidine gel composition
RU2571277C2 (ru) 2010-10-21 2015-12-20 Галдерма С.А. Композиции геля с бримонидином и способы применения

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3452041A (en) * 1965-05-19 1969-06-24 American Home Prod Hydantoin compounds and methods of preparation

Also Published As

Publication number Publication date
PL72695B1 (en) 1974-08-30
BG16040A3 (bg) 1972-05-20
IE33933B1 (en) 1974-12-11
GB1282612A (en) 1972-07-19
DE1956384B2 (de) 1980-02-07
OA03829A (fr) 1971-12-24
IL33348A0 (en) 1970-01-29
BG16037A3 (bg) 1972-05-20
DE1956384C3 (de) 1980-10-09
AT319950B (de) 1975-01-10
BE741529A (xx) 1970-05-11
NO124032B (xx) 1972-02-21
BG16036A3 (bg) 1972-05-20
IE33933L (en) 1970-05-12
USB313531I5 (xx) 1975-01-28
NL6916514A (xx) 1970-05-14
AT310176B (de) 1973-09-25
ES373377A1 (es) 1972-05-16
BG16038A3 (bg) 1972-05-20
BR6914095D0 (pt) 1973-02-13
AT319949B (de) 1975-01-10
BG16188A3 (bg) 1972-07-20
BG16039A3 (bg) 1972-05-20
BG16042A3 (bg) 1972-05-20
IL33348A (en) 1973-04-30
DE1956384A1 (de) 1970-06-11
AT310169B (de) 1973-09-25
BG15573A3 (bg) 1976-06-26
FR2024830B1 (xx) 1973-07-13
BG16043A3 (bg) 1972-05-20
CH521972A (de) 1972-04-30
DK129347B (da) 1974-09-30
SE374920B (xx) 1975-03-24
SE376917B (xx) 1975-06-16
FR2024830A1 (xx) 1970-09-04
US3723432A (en) 1973-03-27
ZA697910B (en) 1971-07-28
BG16041A3 (bg) 1972-05-20
SU366612A3 (xx) 1973-01-16
US3925548A (en) 1975-12-09

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