AR038658A1 - Derivados de 4-aril-2(1h) quinazolinona y 4-aril-quinazolina 2-sustituidas, un proceso para su preparacion, composiciones farmaceuticas y el uso de dichos derivados para la preparacion de un medicamento - Google Patents

Derivados de 4-aril-2(1h) quinazolinona y 4-aril-quinazolina 2-sustituidas, un proceso para su preparacion, composiciones farmaceuticas y el uso de dichos derivados para la preparacion de un medicamento

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Publication number
AR038658A1
AR038658A1 ARP020102233A ARP020102233A AR038658A1 AR 038658 A1 AR038658 A1 AR 038658A1 AR P020102233 A ARP020102233 A AR P020102233A AR P020102233 A ARP020102233 A AR P020102233A AR 038658 A1 AR038658 A1 AR 038658A1
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AR
Argentina
Prior art keywords
preparation
derivatives
aryl
lower alkyl
optionally substituted
Prior art date
Application number
ARP020102233A
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English (en)
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Novartis Ag
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Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26246197&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR038658(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB0114701A external-priority patent/GB0114701D0/en
Priority claimed from GB0114702A external-priority patent/GB0114702D0/en
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of AR038658A1 publication Critical patent/AR038658A1/es

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Abstract

Uso de derivados de 4-aril-2(1H)-quinazolinona y 4-aril-quinazolina 2-sustituidas de fórmula (1) en donde el resto fórmula (2) es seleccionado entre los restos de fórmula (3) ó (4)en donde Y es O ó S; R1 representa de 1 a 3 sustituyentes independientemente seleccionados a partir de OH, SH, halógeno, NO2 (alquilo inferior, alcoxilo inferior, alquenilo inferior, alqueniloxilo inferior, alquinilo inferior, alquiniloxilo inferior, alcanoílo inferior, alquilo inferior-sulfona, alquilo inferior-sulfóxido, o amino) opcionalmente sustituido; R2 es H o (alquilo inferior, arilo, arilalquilo inferior, cicloalquilo, cicloalquilalquilo inferior, o carbonilalquilo inferior) opcionalmente sustituido; R3 representa de 1 a 3 sustituyentes seleccionados a partir de halógeno, (alquilo inferior, alcoxilo inferior, o amino) opcionalmente sustituido; R4' es ciano, halógeno, azida (-N=N=N), o (alquilo inferior, alcoxilo inferior, tioalcoxilo inferior, ariloxilo, arilalcoxilo inferior, o amino) opcionalmente sustituido, o un éster farmacéuticamente aceptable y disociable, o una sal de adición de ácido del mismo, para la preparación de un medicamento para promover la liberación de la hormona paratiroides, una composición farmacéutica que los comprende, el uso de dichos derivados para la preparación de un medicamento para promover la liberación de la hormona paratiroides, por ejemplo para prevenir o tratar condiciones óseas que estén asociadas con el incremento en el agotamiento o resorción de calcio, o en donde sea deseable el estímulo de la formación de hueso y de la fijación de calcio en el hueso. También se describe un proceso, para la preparación de derivados de 4-aril-quinazolinonas.
ARP020102233A 2001-06-15 2002-06-13 Derivados de 4-aril-2(1h) quinazolinona y 4-aril-quinazolina 2-sustituidas, un proceso para su preparacion, composiciones farmaceuticas y el uso de dichos derivados para la preparacion de un medicamento AR038658A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0114701A GB0114701D0 (en) 2001-06-15 2001-06-15 Organic compounds
GB0114702A GB0114702D0 (en) 2001-06-15 2001-06-15 Organic compounds

Publications (1)

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AR038658A1 true AR038658A1 (es) 2005-01-26

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ARP020102233A AR038658A1 (es) 2001-06-15 2002-06-13 Derivados de 4-aril-2(1h) quinazolinona y 4-aril-quinazolina 2-sustituidas, un proceso para su preparacion, composiciones farmaceuticas y el uso de dichos derivados para la preparacion de un medicamento

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US (1) US8476286B2 (es)
EP (2) EP2191832A1 (es)
JP (2) JP4118801B2 (es)
KR (1) KR100699959B1 (es)
CN (1) CN1516587A (es)
AR (1) AR038658A1 (es)
AT (1) ATE447958T1 (es)
AU (1) AU2002325242B2 (es)
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CA (1) CA2449234C (es)
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TW (1) TWI330179B (es)
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Families Citing this family (15)

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AU2007231842B2 (en) * 2002-12-23 2011-04-14 Novartis Ag Derivatives of aryl-quinazoline/aryl-2-amino-phenyl methanone which promote the release of parathyroid hormone
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