JPS5795966A - Novel 2(1h)-quinazolinone derivative - Google Patents
Novel 2(1h)-quinazolinone derivativeInfo
- Publication number
- JPS5795966A JPS5795966A JP17152180A JP17152180A JPS5795966A JP S5795966 A JPS5795966 A JP S5795966A JP 17152180 A JP17152180 A JP 17152180A JP 17152180 A JP17152180 A JP 17152180A JP S5795966 A JPS5795966 A JP S5795966A
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- compound
- formulai
- action
- functional group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:A compound of formulaI(R1 is H, alkanoyloxy, formyl, carboxyl, etc.; A is 4W20C hydrocarbon residue; Y is O, S sulfinyl or sulfonyl; R2 is H, halogen or alkyl; R3 is aryl or alkyl; R4 is H; R5 is H, alkyl, hydroxyalkyl, etc.; R6 is H, alkyl, cycloalkyl, alkenyl, etc.; Z is O or S).
EXAMPLE: 1-n-Propyl-6-(3-methyl-2-butenyloxy)-4-phenyl-2(1H)-quinazolinone.
USE: A medicine having an antilipemic, vasodilator action, inhibitory action on the aggregation of blood platelets, antiallergic action, etc.
PROCESS: A compound of formula III (V is functional group) is reacted with a compound of the formula R1-A-W (W is functional group) to form a (thio)ether bond by the reaction of the groups (V) with (W) and give the compound of formulaI(Y is O or S).
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP17152180A JPS5795966A (en) | 1980-12-04 | 1980-12-04 | Novel 2(1h)-quinazolinone derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP17152180A JPS5795966A (en) | 1980-12-04 | 1980-12-04 | Novel 2(1h)-quinazolinone derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5795966A true JPS5795966A (en) | 1982-06-15 |
Family
ID=15924652
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP17152180A Pending JPS5795966A (en) | 1980-12-04 | 1980-12-04 | Novel 2(1h)-quinazolinone derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5795966A (en) |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0138491A2 (en) * | 1983-09-29 | 1985-04-24 | Ortho Pharmaceutical Corporation | Substituted 2(1H)-quinazolinone-1-alkanoic acids and esters |
EP0138492A2 (en) * | 1983-09-29 | 1985-04-24 | Ortho Pharmaceutical Corporation | Process for preparing substituted 4-alkyl-2(1H) quinazolinone-1-alkanoic acid derivatives |
WO1991009024A1 (en) * | 1989-12-11 | 1991-06-27 | Kyorin Pharmaceutical Co., Ltd. | Quinazoline-3-alkanoic acid derivative, salt thereof, and production thereof |
EP0626373A1 (en) * | 1993-05-26 | 1994-11-30 | Sumitomo Pharmaceuticals Company, Limited | Quinazolinone derivatives |
EP1122253A1 (en) * | 1998-10-16 | 2001-08-08 | Sumitomo Pharmaceuticals Company, Limited | Quinazolinone derivatives |
US7696216B2 (en) | 2002-12-23 | 2010-04-13 | Novartis Ag | Aryl-quinazoline/aryl-2-amino-phenyl methanone derivatives |
US8476286B2 (en) | 2001-06-15 | 2013-07-02 | Novartis Ag | Quinazoline derivatives which promote the release of parathyroid hormone |
-
1980
- 1980-12-04 JP JP17152180A patent/JPS5795966A/en active Pending
Cited By (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0138491A2 (en) * | 1983-09-29 | 1985-04-24 | Ortho Pharmaceutical Corporation | Substituted 2(1H)-quinazolinone-1-alkanoic acids and esters |
EP0138492A2 (en) * | 1983-09-29 | 1985-04-24 | Ortho Pharmaceutical Corporation | Process for preparing substituted 4-alkyl-2(1H) quinazolinone-1-alkanoic acid derivatives |
WO1991009024A1 (en) * | 1989-12-11 | 1991-06-27 | Kyorin Pharmaceutical Co., Ltd. | Quinazoline-3-alkanoic acid derivative, salt thereof, and production thereof |
US5234928A (en) * | 1989-12-11 | 1993-08-10 | Kyorin Pharmaceutical Co., Ltd. | Quinazoline-3-alkanoic acid derivatives, their salts and their preparation processes |
EP0456835B1 (en) * | 1989-12-11 | 1996-05-15 | Kyorin Pharmaceutical Co., Ltd. | Quinazoline-3-alkanoic acid derivative, salt thereof, and production thereof |
EP0626373A1 (en) * | 1993-05-26 | 1994-11-30 | Sumitomo Pharmaceuticals Company, Limited | Quinazolinone derivatives |
EP1122253A1 (en) * | 1998-10-16 | 2001-08-08 | Sumitomo Pharmaceuticals Company, Limited | Quinazolinone derivatives |
EP1122253A4 (en) * | 1998-10-16 | 2003-05-28 | Sumitomo Pharma | Quinazolinone derivatives |
US6645971B1 (en) | 1998-10-16 | 2003-11-11 | Sumitomo Pharmaceuticals Company Limited | Quinazolinone derivatives |
US8476286B2 (en) | 2001-06-15 | 2013-07-02 | Novartis Ag | Quinazoline derivatives which promote the release of parathyroid hormone |
US7696216B2 (en) | 2002-12-23 | 2010-04-13 | Novartis Ag | Aryl-quinazoline/aryl-2-amino-phenyl methanone derivatives |
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