JPS5795966A - Novel 2(1h)-quinazolinone derivative - Google Patents

Novel 2(1h)-quinazolinone derivative

Info

Publication number
JPS5795966A
JPS5795966A JP17152180A JP17152180A JPS5795966A JP S5795966 A JPS5795966 A JP S5795966A JP 17152180 A JP17152180 A JP 17152180A JP 17152180 A JP17152180 A JP 17152180A JP S5795966 A JPS5795966 A JP S5795966A
Authority
JP
Japan
Prior art keywords
alkyl
compound
formulai
action
functional group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP17152180A
Other languages
Japanese (ja)
Inventor
Michihiro Yamamoto
Masao Koshiba
Yukinori Ori
Shunji Aono
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Sumitomo Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co Ltd filed Critical Sumitomo Chemical Co Ltd
Priority to JP17152180A priority Critical patent/JPS5795966A/en
Publication of JPS5795966A publication Critical patent/JPS5795966A/en
Pending legal-status Critical Current

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  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A compound of formulaI(R1 is H, alkanoyloxy, formyl, carboxyl, etc.; A is 4W20C hydrocarbon residue; Y is O, S sulfinyl or sulfonyl; R2 is H, halogen or alkyl; R3 is aryl or alkyl; R4 is H; R5 is H, alkyl, hydroxyalkyl, etc.; R6 is H, alkyl, cycloalkyl, alkenyl, etc.; Z is O or S).
EXAMPLE: 1-n-Propyl-6-(3-methyl-2-butenyloxy)-4-phenyl-2(1H)-quinazolinone.
USE: A medicine having an antilipemic, vasodilator action, inhibitory action on the aggregation of blood platelets, antiallergic action, etc.
PROCESS: A compound of formula III (V is functional group) is reacted with a compound of the formula R1-A-W (W is functional group) to form a (thio)ether bond by the reaction of the groups (V) with (W) and give the compound of formulaI(Y is O or S).
COPYRIGHT: (C)1982,JPO&Japio
JP17152180A 1980-12-04 1980-12-04 Novel 2(1h)-quinazolinone derivative Pending JPS5795966A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP17152180A JPS5795966A (en) 1980-12-04 1980-12-04 Novel 2(1h)-quinazolinone derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP17152180A JPS5795966A (en) 1980-12-04 1980-12-04 Novel 2(1h)-quinazolinone derivative

Publications (1)

Publication Number Publication Date
JPS5795966A true JPS5795966A (en) 1982-06-15

Family

ID=15924652

Family Applications (1)

Application Number Title Priority Date Filing Date
JP17152180A Pending JPS5795966A (en) 1980-12-04 1980-12-04 Novel 2(1h)-quinazolinone derivative

Country Status (1)

Country Link
JP (1) JPS5795966A (en)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0138491A2 (en) * 1983-09-29 1985-04-24 Ortho Pharmaceutical Corporation Substituted 2(1H)-quinazolinone-1-alkanoic acids and esters
EP0138492A2 (en) * 1983-09-29 1985-04-24 Ortho Pharmaceutical Corporation Process for preparing substituted 4-alkyl-2(1H) quinazolinone-1-alkanoic acid derivatives
WO1991009024A1 (en) * 1989-12-11 1991-06-27 Kyorin Pharmaceutical Co., Ltd. Quinazoline-3-alkanoic acid derivative, salt thereof, and production thereof
EP0626373A1 (en) * 1993-05-26 1994-11-30 Sumitomo Pharmaceuticals Company, Limited Quinazolinone derivatives
EP1122253A1 (en) * 1998-10-16 2001-08-08 Sumitomo Pharmaceuticals Company, Limited Quinazolinone derivatives
US7696216B2 (en) 2002-12-23 2010-04-13 Novartis Ag Aryl-quinazoline/aryl-2-amino-phenyl methanone derivatives
US8476286B2 (en) 2001-06-15 2013-07-02 Novartis Ag Quinazoline derivatives which promote the release of parathyroid hormone

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0138491A2 (en) * 1983-09-29 1985-04-24 Ortho Pharmaceutical Corporation Substituted 2(1H)-quinazolinone-1-alkanoic acids and esters
EP0138492A2 (en) * 1983-09-29 1985-04-24 Ortho Pharmaceutical Corporation Process for preparing substituted 4-alkyl-2(1H) quinazolinone-1-alkanoic acid derivatives
WO1991009024A1 (en) * 1989-12-11 1991-06-27 Kyorin Pharmaceutical Co., Ltd. Quinazoline-3-alkanoic acid derivative, salt thereof, and production thereof
US5234928A (en) * 1989-12-11 1993-08-10 Kyorin Pharmaceutical Co., Ltd. Quinazoline-3-alkanoic acid derivatives, their salts and their preparation processes
EP0456835B1 (en) * 1989-12-11 1996-05-15 Kyorin Pharmaceutical Co., Ltd. Quinazoline-3-alkanoic acid derivative, salt thereof, and production thereof
EP0626373A1 (en) * 1993-05-26 1994-11-30 Sumitomo Pharmaceuticals Company, Limited Quinazolinone derivatives
EP1122253A1 (en) * 1998-10-16 2001-08-08 Sumitomo Pharmaceuticals Company, Limited Quinazolinone derivatives
EP1122253A4 (en) * 1998-10-16 2003-05-28 Sumitomo Pharma Quinazolinone derivatives
US6645971B1 (en) 1998-10-16 2003-11-11 Sumitomo Pharmaceuticals Company Limited Quinazolinone derivatives
US8476286B2 (en) 2001-06-15 2013-07-02 Novartis Ag Quinazoline derivatives which promote the release of parathyroid hormone
US7696216B2 (en) 2002-12-23 2010-04-13 Novartis Ag Aryl-quinazoline/aryl-2-amino-phenyl methanone derivatives

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