BG15573A3 - Метод за получаване на нови 2(1н)-хиназолинови - Google Patents
Метод за получаване на нови 2(1н)-хиназолиновиInfo
- Publication number
- BG15573A3 BG15573A3 BG015468A BG1546870A BG15573A3 BG 15573 A3 BG15573 A3 BG 15573A3 BG 015468 A BG015468 A BG 015468A BG 1546870 A BG1546870 A BG 1546870A BG 15573 A3 BG15573 A3 BG 15573A3
- Authority
- BG
- Bulgaria
- Prior art keywords
- quinazolines
- obtaining new
- obtaining
- new
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
- C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US00775201A US3723432A (en) | 1968-11-12 | 1968-11-12 | 1-substituted-4-aryl-2(1h)-quinazolinones and their preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
BG15573A3 true BG15573A3 (bg) | 1976-06-26 |
Family
ID=25103642
Family Applications (10)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG015055A BG16042A3 (bg) | 1968-11-12 | 1968-11-12 | Метод за получаване на нови 2(1н)-хиназолинони |
BG013325A BG16188A3 (bg) | 1968-11-12 | 1969-11-10 | Метод за получаване на нови 2(1н)-хиназолинони |
BG014693A BG16037A3 (bg) | 1968-11-12 | 1969-11-10 | Метод за получаване на нови 2(1н)-хиназолинони |
BG014692A BG16036A3 (bg) | 1968-11-12 | 1969-11-10 | Метод за получавне на нови 2(1н)-хиназолинони |
BG015469A BG16043A3 (bg) | 1968-11-12 | 1969-11-10 | Метод за получаване на нови 2(1н)-хиназолинони |
BG014694A BG16038A3 (bg) | 1968-11-12 | 1969-11-10 | Метод за получаване на 1-изопропил-7-метил- -6-амино-4-фенил-2(1н)-хиназолинон |
BG014696A BG16040A3 (bg) | 1968-11-12 | 1969-11-10 | Метод за получаване на нови 2(1н) - хиназолинони |
BG014695A BG16039A3 (bg) | 1968-11-12 | 1969-11-10 | Метод за получаване на нови 2(1н) - хиназолинони |
BG014697A BG16041A3 (bg) | 1968-11-12 | 1970-05-16 | Метод за получаване на нови2(1н)-хиназолинони |
BG015468A BG15573A3 (bg) | 1968-11-12 | 1970-08-13 | Метод за получаване на нови 2(1н)-хиназолинови |
Family Applications Before (9)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG015055A BG16042A3 (bg) | 1968-11-12 | 1968-11-12 | Метод за получаване на нови 2(1н)-хиназолинони |
BG013325A BG16188A3 (bg) | 1968-11-12 | 1969-11-10 | Метод за получаване на нови 2(1н)-хиназолинони |
BG014693A BG16037A3 (bg) | 1968-11-12 | 1969-11-10 | Метод за получаване на нови 2(1н)-хиназолинони |
BG014692A BG16036A3 (bg) | 1968-11-12 | 1969-11-10 | Метод за получавне на нови 2(1н)-хиназолинони |
BG015469A BG16043A3 (bg) | 1968-11-12 | 1969-11-10 | Метод за получаване на нови 2(1н)-хиназолинони |
BG014694A BG16038A3 (bg) | 1968-11-12 | 1969-11-10 | Метод за получаване на 1-изопропил-7-метил- -6-амино-4-фенил-2(1н)-хиназолинон |
BG014696A BG16040A3 (bg) | 1968-11-12 | 1969-11-10 | Метод за получаване на нови 2(1н) - хиназолинони |
BG014695A BG16039A3 (bg) | 1968-11-12 | 1969-11-10 | Метод за получаване на нови 2(1н) - хиназолинони |
BG014697A BG16041A3 (bg) | 1968-11-12 | 1970-05-16 | Метод за получаване на нови2(1н)-хиназолинони |
Country Status (19)
Country | Link |
---|---|
US (2) | US3723432A (bg) |
AT (4) | AT310176B (bg) |
BE (1) | BE741529A (bg) |
BG (10) | BG16042A3 (bg) |
BR (1) | BR6914095D0 (bg) |
CH (1) | CH521972A (bg) |
DE (1) | DE1956384C3 (bg) |
DK (1) | DK129347B (bg) |
ES (1) | ES373377A1 (bg) |
FR (1) | FR2024830B1 (bg) |
GB (1) | GB1282612A (bg) |
IE (1) | IE33933B1 (bg) |
IL (1) | IL33348A (bg) |
NL (1) | NL6916514A (bg) |
NO (1) | NO124032B (bg) |
OA (1) | OA03829A (bg) |
PL (1) | PL72695B1 (bg) |
SE (2) | SE374920B (bg) |
ZA (1) | ZA697910B (bg) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3923803A (en) * | 1968-07-18 | 1975-12-02 | Sumitomo Chemical Co | 2(1H)-Quinozalinones and process therefor |
US3642791A (en) * | 1969-08-13 | 1972-02-15 | Sandoz Ag | Morpholino-1-substituted-2(1h)-quinazolinones |
US4208343A (en) * | 1970-10-30 | 1980-06-17 | Westinghouse Electric Corp. | 2,4 Diamino benzonitrile |
BE785937A (fr) * | 1971-07-08 | 1973-01-08 | Sandoz Sa | Nouveaux derives de la quinazoline, leur preparation et leur application comme medicaments |
US3937705A (en) * | 1972-03-09 | 1976-02-10 | Sandoz, Inc. | 1-isopropyl-7-methyl-4-(p-fluorophenyl)-2(1h)-quinazolinone |
US4071516A (en) * | 1976-08-20 | 1978-01-31 | Sandoz, Inc. | 4-(Acyloxyphenyl)-quinazolin-2(1H)-ones |
US4064246A (en) * | 1976-10-12 | 1977-12-20 | Sandoz, Inc. | Hydroxymethyl-substituted-2(1H)-quinazolinones |
US4160092A (en) * | 1977-06-16 | 1979-07-03 | E. I. Du Pont De Nemours And Company | Quinazolinone oxides and their use as intermediates for pharmaceutical agents |
US4224328A (en) * | 1979-04-11 | 1980-09-23 | Sandoz, Inc. | Methods with 1-substituted-4-aryl-quinazolin-2(1H)-ones and thiones and pyrido[2,3-d]pyrimidin-2-ones as platelet aggregation inhibitors |
CH645362A5 (de) * | 1979-07-05 | 1984-09-28 | Sandoz Ag | Verfahren zur herstellung von 4-phenyl-2(1h)-chinazolinonen. |
FR2676042B1 (fr) * | 1991-05-02 | 1993-07-23 | Commissariat Energie Atomique | Procede de preparation d'un borohydrure de metal alcalin tel que le borohydrure de lithium. |
US7230000B1 (en) | 1999-10-27 | 2007-06-12 | Cytokinetics, Incorporated | Methods and compositions utilizing quinazolinones |
US6545004B1 (en) | 1999-10-27 | 2003-04-08 | Cytokinetics, Inc. | Methods and compositions utilizing quinazolinones |
AR038658A1 (es) | 2001-06-15 | 2005-01-26 | Novartis Ag | Derivados de 4-aril-2(1h) quinazolinona y 4-aril-quinazolina 2-sustituidas, un proceso para su preparacion, composiciones farmaceuticas y el uso de dichos derivados para la preparacion de un medicamento |
WO2003043995A1 (en) * | 2001-11-20 | 2003-05-30 | Cytokinetics, Inc. | Process for the racemization of chiral quinazolinones |
EP1480980A4 (en) * | 2002-02-15 | 2005-04-20 | Cytokinetics Inc | SYNTHESIS OF QUINAZOLINONES |
BR0309892A2 (pt) * | 2002-05-09 | 2011-04-05 | Cytokinetics Inc | composto, composição, métodos para modular a atividade da cinesina de ksp, para inibir a ksp, e para o tratamento de uma doença proliferativa celular, e, uso de um composto |
JP2005530785A (ja) | 2002-05-09 | 2005-10-13 | サイトキネティクス・インコーポレーテッド | 化合物、組成物、及び方法 |
US7038048B2 (en) * | 2002-05-23 | 2006-05-02 | Cytokinetics, Inc. | 3H-pyridopyrimidin-4-one compounds, compositions, and methods of their use |
US7041676B2 (en) * | 2002-06-14 | 2006-05-09 | Cytokinetics, Inc. | Compounds, compositions, and methods |
AU2003256805A1 (en) * | 2002-07-23 | 2004-02-09 | Cytokinetics, Inc. | Compounds compositions and methods |
EP1539180A4 (en) * | 2002-08-21 | 2006-08-30 | Cytokinetics Inc | COMPOUNDS, COMPOSITIONS AND METHODS |
JP2006501306A (ja) * | 2002-09-30 | 2006-01-12 | サイトキネティクス・インコーポレーテッド | 化合物、組成物および方法 |
GB0230015D0 (en) * | 2002-12-23 | 2003-01-29 | Novartis Ag | Organic compounds |
US7439241B2 (en) | 2003-05-27 | 2008-10-21 | Galderma Laboratories, Inc. | Compounds, formulations, and methods for treating or preventing rosacea |
US8410102B2 (en) | 2003-05-27 | 2013-04-02 | Galderma Laboratories Inc. | Methods and compositions for treating or preventing erythema |
JP2007510652A (ja) * | 2003-11-03 | 2007-04-26 | サイトキネティクス・インコーポレーテッド | ピリミジン−4−オン化合物、組成物、および方法 |
WO2005046588A2 (en) * | 2003-11-07 | 2005-05-26 | Cytokinetics, Inc. | Compounds, compositions, and methods |
JP2007513154A (ja) * | 2003-12-08 | 2007-05-24 | サイトキネティクス・インコーポレーテッド | 化合物、組成物及び方法 |
WO2009002808A2 (en) * | 2007-06-22 | 2008-12-31 | Arqule, Inc. | Quinazolinone compounds and methods of use thereof |
US8058469B2 (en) * | 2008-11-03 | 2011-11-15 | Sabic Innovative Plastics Ip B.V. | Method for making carbamates, ureas and isocyanates |
EP2329849B1 (en) | 2009-11-18 | 2015-04-29 | Galderma Research & Development | Combination of alpha-2 adrenergic receptor agonist and non-steroidal anti-inflammatory agent for treating or preventing an inflammatory skin disorder |
US8394800B2 (en) | 2009-11-19 | 2013-03-12 | Galderma Laboratories, L.P. | Method for treating psoriasis |
WO2011117377A2 (en) | 2010-03-26 | 2011-09-29 | Galderma Research & Development | Improved methods and compositions for safe and effective treatment of erythema |
WO2011117378A2 (en) | 2010-03-26 | 2011-09-29 | Galderma Research & Development | Improved methods and compositions for safe and effective treatment of telangiectasia |
US8053427B1 (en) | 2010-10-21 | 2011-11-08 | Galderma R&D SNC | Brimonidine gel composition |
JP2013540143A (ja) | 2010-10-21 | 2013-10-31 | ガルデルマ・ソシエテ・アノニム | ブリモニジンゲル組成物及び使用方法 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3452041A (en) * | 1965-05-19 | 1969-06-24 | American Home Prod | Hydantoin compounds and methods of preparation |
-
1968
- 1968-11-12 BG BG015055A patent/BG16042A3/bg unknown
- 1968-11-12 US US00775201A patent/US3723432A/en not_active Expired - Lifetime
-
1969
- 1969-10-31 CH CH1624569A patent/CH521972A/de not_active IP Right Cessation
- 1969-10-31 GB GB53620/69A patent/GB1282612A/en not_active Expired
- 1969-11-03 NL NL6916514A patent/NL6916514A/xx not_active Application Discontinuation
- 1969-11-07 FR FR696938404A patent/FR2024830B1/fr not_active Expired
- 1969-11-10 AT AT993571A patent/AT310176B/de not_active IP Right Cessation
- 1969-11-10 IE IE1526/69A patent/IE33933B1/xx unknown
- 1969-11-10 BG BG013325A patent/BG16188A3/bg unknown
- 1969-11-10 BG BG014693A patent/BG16037A3/bg unknown
- 1969-11-10 BG BG014692A patent/BG16036A3/bg unknown
- 1969-11-10 AT AT1053269A patent/AT310169B/de not_active IP Right Cessation
- 1969-11-10 NO NO4445/69A patent/NO124032B/no unknown
- 1969-11-10 AT AT993071A patent/AT319949B/de not_active IP Right Cessation
- 1969-11-10 BG BG015469A patent/BG16043A3/bg unknown
- 1969-11-10 AT AT993271A patent/AT319950B/de not_active IP Right Cessation
- 1969-11-10 BG BG014694A patent/BG16038A3/bg unknown
- 1969-11-10 BG BG014696A patent/BG16040A3/bg unknown
- 1969-11-10 DE DE1956384A patent/DE1956384C3/de not_active Expired
- 1969-11-10 OA OA53783A patent/OA03829A/xx unknown
- 1969-11-10 BE BE741529A patent/BE741529A/xx unknown
- 1969-11-10 BG BG014695A patent/BG16039A3/bg unknown
- 1969-11-10 ES ES373377A patent/ES373377A1/es not_active Expired
- 1969-11-11 DK DK597169AA patent/DK129347B/da unknown
- 1969-11-11 SE SE6915448A patent/SE374920B/xx unknown
- 1969-11-11 SE SE7213438A patent/SE376917B/xx unknown
- 1969-11-11 BR BR214095/69A patent/BR6914095D0/pt unknown
- 1969-11-11 IL IL33348A patent/IL33348A/xx unknown
- 1969-11-12 PL PL1969136872A patent/PL72695B1/pl unknown
- 1969-11-12 ZA ZA697910A patent/ZA697910B/xx unknown
-
1970
- 1970-05-16 BG BG014697A patent/BG16041A3/bg unknown
- 1970-08-13 BG BG015468A patent/BG15573A3/bg unknown
-
1972
- 1972-12-08 US US313531A patent/US3925548A/en not_active Expired - Lifetime
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