AT319950B - Verfahren zur Herstellung neuer 2(1H)-Chinazolinone sowie von ihren Säureadditionssalzen - Google Patents
Verfahren zur Herstellung neuer 2(1H)-Chinazolinone sowie von ihren SäureadditionssalzenInfo
- Publication number
- AT319950B AT319950B AT993271A AT993271A AT319950B AT 319950 B AT319950 B AT 319950B AT 993271 A AT993271 A AT 993271A AT 993271 A AT993271 A AT 993271A AT 319950 B AT319950 B AT 319950B
- Authority
- AT
- Austria
- Prior art keywords
- quinazolinones
- preparation
- new
- acid addition
- addition salts
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
- C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US00775201A US3723432A (en) | 1968-11-12 | 1968-11-12 | 1-substituted-4-aryl-2(1h)-quinazolinones and their preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
AT319950B true AT319950B (de) | 1975-01-10 |
Family
ID=25103642
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT993071A AT319949B (de) | 1968-11-12 | 1969-11-10 | Verfahren zur Herstellung von neuen 2(1H)-Chinazolinonen sowie von ihren Säureadditionssalzen |
AT993571A AT310176B (de) | 1968-11-12 | 1969-11-10 | Verfahren zur Herstellung von neuen 2(1H)-Chinazolinonen |
AT1053269A AT310169B (de) | 1968-11-12 | 1969-11-10 | Verfahren zur Herstellung von neuen 2(1H)-Chinazolinonen |
AT993271A AT319950B (de) | 1968-11-12 | 1969-11-10 | Verfahren zur Herstellung neuer 2(1H)-Chinazolinone sowie von ihren Säureadditionssalzen |
Family Applications Before (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT993071A AT319949B (de) | 1968-11-12 | 1969-11-10 | Verfahren zur Herstellung von neuen 2(1H)-Chinazolinonen sowie von ihren Säureadditionssalzen |
AT993571A AT310176B (de) | 1968-11-12 | 1969-11-10 | Verfahren zur Herstellung von neuen 2(1H)-Chinazolinonen |
AT1053269A AT310169B (de) | 1968-11-12 | 1969-11-10 | Verfahren zur Herstellung von neuen 2(1H)-Chinazolinonen |
Country Status (19)
Country | Link |
---|---|
US (2) | US3723432A (de) |
AT (4) | AT319949B (de) |
BE (1) | BE741529A (de) |
BG (10) | BG16042A3 (de) |
BR (1) | BR6914095D0 (de) |
CH (1) | CH521972A (de) |
DE (1) | DE1956384C3 (de) |
DK (1) | DK129347B (de) |
ES (1) | ES373377A1 (de) |
FR (1) | FR2024830B1 (de) |
GB (1) | GB1282612A (de) |
IE (1) | IE33933B1 (de) |
IL (1) | IL33348A (de) |
NL (1) | NL6916514A (de) |
NO (1) | NO124032B (de) |
OA (1) | OA03829A (de) |
PL (1) | PL72695B1 (de) |
SE (2) | SE376917B (de) |
ZA (1) | ZA697910B (de) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3923803A (en) * | 1968-07-18 | 1975-12-02 | Sumitomo Chemical Co | 2(1H)-Quinozalinones and process therefor |
US3642791A (en) * | 1969-08-13 | 1972-02-15 | Sandoz Ag | Morpholino-1-substituted-2(1h)-quinazolinones |
US4208343A (en) * | 1970-10-30 | 1980-06-17 | Westinghouse Electric Corp. | 2,4 Diamino benzonitrile |
BE785937A (fr) * | 1971-07-08 | 1973-01-08 | Sandoz Sa | Nouveaux derives de la quinazoline, leur preparation et leur application comme medicaments |
US3937705A (en) * | 1972-03-09 | 1976-02-10 | Sandoz, Inc. | 1-isopropyl-7-methyl-4-(p-fluorophenyl)-2(1h)-quinazolinone |
US4071516A (en) * | 1976-08-20 | 1978-01-31 | Sandoz, Inc. | 4-(Acyloxyphenyl)-quinazolin-2(1H)-ones |
US4064246A (en) * | 1976-10-12 | 1977-12-20 | Sandoz, Inc. | Hydroxymethyl-substituted-2(1H)-quinazolinones |
US4160092A (en) * | 1977-06-16 | 1979-07-03 | E. I. Du Pont De Nemours And Company | Quinazolinone oxides and their use as intermediates for pharmaceutical agents |
US4224328A (en) * | 1979-04-11 | 1980-09-23 | Sandoz, Inc. | Methods with 1-substituted-4-aryl-quinazolin-2(1H)-ones and thiones and pyrido[2,3-d]pyrimidin-2-ones as platelet aggregation inhibitors |
CH645362A5 (de) * | 1979-07-05 | 1984-09-28 | Sandoz Ag | Verfahren zur herstellung von 4-phenyl-2(1h)-chinazolinonen. |
FR2676042B1 (fr) * | 1991-05-02 | 1993-07-23 | Commissariat Energie Atomique | Procede de preparation d'un borohydrure de metal alcalin tel que le borohydrure de lithium. |
US6545004B1 (en) * | 1999-10-27 | 2003-04-08 | Cytokinetics, Inc. | Methods and compositions utilizing quinazolinones |
US7230000B1 (en) * | 1999-10-27 | 2007-06-12 | Cytokinetics, Incorporated | Methods and compositions utilizing quinazolinones |
AR038658A1 (es) * | 2001-06-15 | 2005-01-26 | Novartis Ag | Derivados de 4-aril-2(1h) quinazolinona y 4-aril-quinazolina 2-sustituidas, un proceso para su preparacion, composiciones farmaceuticas y el uso de dichos derivados para la preparacion de un medicamento |
WO2003043995A1 (en) * | 2001-11-20 | 2003-05-30 | Cytokinetics, Inc. | Process for the racemization of chiral quinazolinones |
CA2475879A1 (en) * | 2002-02-15 | 2003-08-28 | Cytokinetics, Inc. | Synthesis of quinazolinones |
US7214800B2 (en) * | 2002-05-09 | 2007-05-08 | Cytokinetics, Inc. | Compounds, compositions, and methods |
US7166595B2 (en) * | 2002-05-09 | 2007-01-23 | Cytokinetics, Inc. | Compounds, methods and compositions |
WO2003103575A2 (en) * | 2002-05-23 | 2003-12-18 | Cytokinetics, Inc. | Compounds, compositions, and methods |
WO2003106426A1 (en) * | 2002-06-14 | 2003-12-24 | Cytokinetics, Inc. | Compounds, compositions, and methods |
EP1537089A4 (de) * | 2002-07-23 | 2008-04-16 | Cytokinetics Inc | Verbindungen, zusammenstellungen und verfahren |
US20040048853A1 (en) * | 2002-08-21 | 2004-03-11 | Gustave Bergnes | Compounds, compositions, and methods |
WO2004034972A2 (en) * | 2002-09-30 | 2004-04-29 | Cytokinetics, Inc. | Compounds, compositions, and methods |
GB0230015D0 (en) * | 2002-12-23 | 2003-01-29 | Novartis Ag | Organic compounds |
US8410102B2 (en) | 2003-05-27 | 2013-04-02 | Galderma Laboratories Inc. | Methods and compositions for treating or preventing erythema |
US7439241B2 (en) | 2003-05-27 | 2008-10-21 | Galderma Laboratories, Inc. | Compounds, formulations, and methods for treating or preventing rosacea |
EP1682534A2 (de) * | 2003-11-03 | 2006-07-26 | Cytokinetics, Inc. | Pyrimidin-4-onverbindungen, zusammensetzungen und verfahren |
EP1680420A4 (de) * | 2003-11-07 | 2008-09-24 | Cytokinetics Inc | Verbindungen, zusammensetzungen und verfahren |
EP1692112A4 (de) * | 2003-12-08 | 2008-09-24 | Cytokinetics Inc | Verbindungen, zusammensetzungen und verfahren |
BRPI0813355A2 (pt) * | 2007-06-22 | 2014-12-30 | Arqule Inc | Compostos de quinazolinona e métodos de uso dos mesmos |
US8058469B2 (en) * | 2008-11-03 | 2011-11-15 | Sabic Innovative Plastics Ip B.V. | Method for making carbamates, ureas and isocyanates |
EP2329849B1 (de) | 2009-11-18 | 2015-04-29 | Galderma Research & Development | Kombination aus einem Alpha-2-Adrenozeptor-Agonisten und einem nichtsteroidalen entzündungshemmenden Mittel zur Behandlung oder Prävention einer Entzündungskrankheit der Haut |
US8394800B2 (en) * | 2009-11-19 | 2013-03-12 | Galderma Laboratories, L.P. | Method for treating psoriasis |
WO2011117377A2 (en) | 2010-03-26 | 2011-09-29 | Galderma Research & Development | Improved methods and compositions for safe and effective treatment of erythema |
US8916562B2 (en) | 2010-03-26 | 2014-12-23 | Galderma Research & Development Snc | Methods and compositions for safe and effective treatment of telangiectasia |
NO2444068T3 (de) | 2010-10-21 | 2014-12-20 | ||
US8053427B1 (en) | 2010-10-21 | 2011-11-08 | Galderma R&D SNC | Brimonidine gel composition |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3452041A (en) * | 1965-05-19 | 1969-06-24 | American Home Prod | Hydantoin compounds and methods of preparation |
-
1968
- 1968-11-12 US US00775201A patent/US3723432A/en not_active Expired - Lifetime
- 1968-11-12 BG BG015055A patent/BG16042A3/bg unknown
-
1969
- 1969-10-31 GB GB53620/69A patent/GB1282612A/en not_active Expired
- 1969-10-31 CH CH1624569A patent/CH521972A/de not_active IP Right Cessation
- 1969-11-03 NL NL6916514A patent/NL6916514A/xx not_active Application Discontinuation
- 1969-11-07 FR FR696938404A patent/FR2024830B1/fr not_active Expired
- 1969-11-10 DE DE1956384A patent/DE1956384C3/de not_active Expired
- 1969-11-10 AT AT993071A patent/AT319949B/de not_active IP Right Cessation
- 1969-11-10 OA OA53783A patent/OA03829A/xx unknown
- 1969-11-10 AT AT993571A patent/AT310176B/de not_active IP Right Cessation
- 1969-11-10 ES ES373377A patent/ES373377A1/es not_active Expired
- 1969-11-10 IE IE1526/69A patent/IE33933B1/xx unknown
- 1969-11-10 BG BG014693A patent/BG16037A3/bg unknown
- 1969-11-10 BG BG015469A patent/BG16043A3/bg unknown
- 1969-11-10 BG BG014692A patent/BG16036A3/bg unknown
- 1969-11-10 BG BG013325A patent/BG16188A3/bg unknown
- 1969-11-10 BG BG014694A patent/BG16038A3/bg unknown
- 1969-11-10 NO NO4445/69A patent/NO124032B/no unknown
- 1969-11-10 BG BG014696A patent/BG16040A3/bg unknown
- 1969-11-10 BG BG014695A patent/BG16039A3/bg unknown
- 1969-11-10 AT AT1053269A patent/AT310169B/de not_active IP Right Cessation
- 1969-11-10 AT AT993271A patent/AT319950B/de not_active IP Right Cessation
- 1969-11-10 BE BE741529A patent/BE741529A/xx unknown
- 1969-11-11 BR BR214095/69A patent/BR6914095D0/pt unknown
- 1969-11-11 DK DK597169AA patent/DK129347B/da unknown
- 1969-11-11 SE SE7213438A patent/SE376917B/xx unknown
- 1969-11-11 IL IL33348A patent/IL33348A/xx unknown
- 1969-11-11 SE SE6915448A patent/SE374920B/xx unknown
- 1969-11-12 ZA ZA697910A patent/ZA697910B/xx unknown
- 1969-11-12 PL PL1969136872A patent/PL72695B1/pl unknown
-
1970
- 1970-05-16 BG BG014697A patent/BG16041A3/bg unknown
- 1970-08-13 BG BG015468A patent/BG15573A3/bg unknown
-
1972
- 1972-12-08 US US313531A patent/US3925548A/en not_active Expired - Lifetime
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ELJ | Ceased due to non-payment of the annual fee |