DK129347B - Analogifremgangsmåde til fremstilling af 4-phenyl-2(1H)-quinazolinoner eller syreadditionssalte heraf. - Google Patents

Analogifremgangsmåde til fremstilling af 4-phenyl-2(1H)-quinazolinoner eller syreadditionssalte heraf.

Info

Publication number
DK129347B
DK129347B DK597169AA DK597169A DK129347B DK 129347 B DK129347 B DK 129347B DK 597169A A DK597169A A DK 597169AA DK 597169 A DK597169 A DK 597169A DK 129347 B DK129347 B DK 129347B
Authority
DK
Denmark
Prior art keywords
quinazolinones
phenyl
preparation
acid addition
addition salts
Prior art date
Application number
DK597169AA
Other languages
Danish (da)
English (en)
Other versions
DK129347C (de
Inventor
H Ott
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Priority to DK585973A priority Critical patent/DK130738B/da
Priority to DK586173A priority patent/DK130739B/da
Publication of DK129347B publication Critical patent/DK129347B/da
Application granted granted Critical
Publication of DK129347C publication Critical patent/DK129347C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DK597169AA 1968-11-12 1969-11-11 Analogifremgangsmåde til fremstilling af 4-phenyl-2(1H)-quinazolinoner eller syreadditionssalte heraf. DK129347B (da)

Priority Applications (2)

Application Number Priority Date Filing Date Title
DK585973A DK130738B (da) 1968-11-12 1973-10-30 Analogifremgangsmåde til fremstilling af nitro- eller aminosubstituerede 1-alkyl-4-phenyl-2(1H)-quinazolinoner eller syreadditionssalte heraf.
DK586173A DK130739B (da) 1968-11-12 1973-10-30 Analogifremgangsmåde til fremstilling af aminosubstituerede 1-alkyl-4-phenyl-2(1H)-quinazolinoner eller syreadditionssalte heraf.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US00775201A US3723432A (en) 1968-11-12 1968-11-12 1-substituted-4-aryl-2(1h)-quinazolinones and their preparation

Publications (2)

Publication Number Publication Date
DK129347B true DK129347B (da) 1974-09-30
DK129347C DK129347C (de) 1975-02-17

Family

ID=25103642

Family Applications (1)

Application Number Title Priority Date Filing Date
DK597169AA DK129347B (da) 1968-11-12 1969-11-11 Analogifremgangsmåde til fremstilling af 4-phenyl-2(1H)-quinazolinoner eller syreadditionssalte heraf.

Country Status (19)

Country Link
US (2) US3723432A (de)
AT (4) AT310176B (de)
BE (1) BE741529A (de)
BG (10) BG16042A3 (de)
BR (1) BR6914095D0 (de)
CH (1) CH521972A (de)
DE (1) DE1956384C3 (de)
DK (1) DK129347B (de)
ES (1) ES373377A1 (de)
FR (1) FR2024830B1 (de)
GB (1) GB1282612A (de)
IE (1) IE33933B1 (de)
IL (1) IL33348A (de)
NL (1) NL6916514A (de)
NO (1) NO124032B (de)
OA (1) OA03829A (de)
PL (1) PL72695B1 (de)
SE (2) SE374920B (de)
ZA (1) ZA697910B (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3923803A (en) * 1968-07-18 1975-12-02 Sumitomo Chemical Co 2(1H)-Quinozalinones and process therefor
US3642791A (en) * 1969-08-13 1972-02-15 Sandoz Ag Morpholino-1-substituted-2(1h)-quinazolinones
US4208343A (en) * 1970-10-30 1980-06-17 Westinghouse Electric Corp. 2,4 Diamino benzonitrile
BE785937A (fr) * 1971-07-08 1973-01-08 Sandoz Sa Nouveaux derives de la quinazoline, leur preparation et leur application comme medicaments
US3937705A (en) * 1972-03-09 1976-02-10 Sandoz, Inc. 1-isopropyl-7-methyl-4-(p-fluorophenyl)-2(1h)-quinazolinone
US4064246A (en) * 1976-10-12 1977-12-20 Sandoz, Inc. Hydroxymethyl-substituted-2(1H)-quinazolinones
US4071516A (en) * 1976-08-20 1978-01-31 Sandoz, Inc. 4-(Acyloxyphenyl)-quinazolin-2(1H)-ones
US4160092A (en) * 1977-06-16 1979-07-03 E. I. Du Pont De Nemours And Company Quinazolinone oxides and their use as intermediates for pharmaceutical agents
US4224328A (en) * 1979-04-11 1980-09-23 Sandoz, Inc. Methods with 1-substituted-4-aryl-quinazolin-2(1H)-ones and thiones and pyrido[2,3-d]pyrimidin-2-ones as platelet aggregation inhibitors
CH645362A5 (de) * 1979-07-05 1984-09-28 Sandoz Ag Verfahren zur herstellung von 4-phenyl-2(1h)-chinazolinonen.
FR2676042B1 (fr) * 1991-05-02 1993-07-23 Commissariat Energie Atomique Procede de preparation d'un borohydrure de metal alcalin tel que le borohydrure de lithium.
US6545004B1 (en) 1999-10-27 2003-04-08 Cytokinetics, Inc. Methods and compositions utilizing quinazolinones
US7230000B1 (en) 1999-10-27 2007-06-12 Cytokinetics, Incorporated Methods and compositions utilizing quinazolinones
AR038658A1 (es) * 2001-06-15 2005-01-26 Novartis Ag Derivados de 4-aril-2(1h) quinazolinona y 4-aril-quinazolina 2-sustituidas, un proceso para su preparacion, composiciones farmaceuticas y el uso de dichos derivados para la preparacion de un medicamento
WO2003043995A1 (en) * 2001-11-20 2003-05-30 Cytokinetics, Inc. Process for the racemization of chiral quinazolinones
CA2475879A1 (en) * 2002-02-15 2003-08-28 Cytokinetics, Inc. Synthesis of quinazolinones
JP2005530785A (ja) 2002-05-09 2005-10-13 サイトキネティクス・インコーポレーテッド 化合物、組成物、及び方法
PL373412A1 (en) * 2002-05-09 2005-08-22 Cytokinetics, Inc. Pyrimidinone compounds, compositions and methods of their use for treating cellular proliferative diseases
US7038048B2 (en) * 2002-05-23 2006-05-02 Cytokinetics, Inc. 3H-pyridopyrimidin-4-one compounds, compositions, and methods of their use
US7041676B2 (en) * 2002-06-14 2006-05-09 Cytokinetics, Inc. Compounds, compositions, and methods
US7211580B2 (en) * 2002-07-23 2007-05-01 Cytokinetics, Incorporated Compounds, compositions, and methods
JP2005536553A (ja) * 2002-08-21 2005-12-02 サイトキネティクス・インコーポレーテッド 化合物、組成物および方法
US7557115B2 (en) * 2002-09-30 2009-07-07 Cytokinetics, Inc. Compounds, compositions, and methods
GB0230015D0 (en) * 2002-12-23 2003-01-29 Novartis Ag Organic compounds
US7439241B2 (en) 2003-05-27 2008-10-21 Galderma Laboratories, Inc. Compounds, formulations, and methods for treating or preventing rosacea
US8410102B2 (en) 2003-05-27 2013-04-02 Galderma Laboratories Inc. Methods and compositions for treating or preventing erythema
WO2005041888A2 (en) * 2003-11-03 2005-05-12 Cytokinetics, Inc. Pyrimidin-4-one compounds, compositions and methods
JP2007510660A (ja) * 2003-11-07 2007-04-26 サイトキネティクス・インコーポレーテッド 化合物、組成物及び方法
US7439254B2 (en) * 2003-12-08 2008-10-21 Cytokinetics, Inc. Compounds, compositions, and methods
MX2009013815A (es) * 2007-06-22 2010-03-01 Arqule Inc Compuestos de quinazolinona y metodos de uso para los mismos.
US8058469B2 (en) * 2008-11-03 2011-11-15 Sabic Innovative Plastics Ip B.V. Method for making carbamates, ureas and isocyanates
EP2329849B1 (de) 2009-11-18 2015-04-29 Galderma Research & Development Kombination aus einem Alpha-2-Adrenozeptor-Agonisten und einem nichtsteroidalen entzündungshemmenden Mittel zur Behandlung oder Prävention einer Entzündungskrankheit der Haut
US8394800B2 (en) 2009-11-19 2013-03-12 Galderma Laboratories, L.P. Method for treating psoriasis
BR112012024476A2 (pt) 2010-03-26 2017-03-01 Galderma Res & Dev método para fornecer um tratamento seguro e efetivo da telangiectasia e método de produzir um produto embalado
KR20150055082A (ko) 2010-03-26 2015-05-20 갈데르마 리써어치 앤드 디벨로프먼트 홍반의 유효하고 안전한 치료를 위한 개선된 방법 및 조성물
US8053427B1 (en) 2010-10-21 2011-11-08 Galderma R&D SNC Brimonidine gel composition
RU2571277C2 (ru) 2010-10-21 2015-12-20 Галдерма С.А. Композиции геля с бримонидином и способы применения

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3452041A (en) * 1965-05-19 1969-06-24 American Home Prod Hydantoin compounds and methods of preparation

Also Published As

Publication number Publication date
USB313531I5 (de) 1975-01-28
BG16039A3 (bg) 1972-05-20
PL72695B1 (en) 1974-08-30
BG16042A3 (bg) 1972-05-20
BG16043A3 (bg) 1972-05-20
BG16040A3 (bg) 1972-05-20
BG16036A3 (bg) 1972-05-20
NO124032B (de) 1972-02-21
BG16041A3 (bg) 1972-05-20
AT310176B (de) 1973-09-25
AT319949B (de) 1975-01-10
US3723432A (en) 1973-03-27
ZA697910B (en) 1971-07-28
US3925548A (en) 1975-12-09
BE741529A (de) 1970-05-11
BR6914095D0 (pt) 1973-02-13
DE1956384B2 (de) 1980-02-07
AT310169B (de) 1973-09-25
BG16038A3 (bg) 1972-05-20
FR2024830B1 (de) 1973-07-13
SE374920B (de) 1975-03-24
IE33933L (en) 1970-05-12
GB1282612A (en) 1972-07-19
NL6916514A (de) 1970-05-14
ES373377A1 (es) 1972-05-16
IL33348A (en) 1973-04-30
IL33348A0 (en) 1970-01-29
DE1956384A1 (de) 1970-06-11
BG16037A3 (bg) 1972-05-20
OA03829A (fr) 1971-12-24
BG15573A3 (bg) 1976-06-26
DE1956384C3 (de) 1980-10-09
BG16188A3 (bg) 1972-07-20
CH521972A (de) 1972-04-30
SE376917B (de) 1975-06-16
SU366612A3 (de) 1973-01-16
IE33933B1 (en) 1974-12-11
AT319950B (de) 1975-01-10
FR2024830A1 (de) 1970-09-04
DK129347C (de) 1975-02-17

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