CH521972A - Verfahren zur Herstellung von 2(1H)-Chinazolinonen - Google Patents
Verfahren zur Herstellung von 2(1H)-ChinazolinonenInfo
- Publication number
- CH521972A CH521972A CH1624569A CH1624569A CH521972A CH 521972 A CH521972 A CH 521972A CH 1624569 A CH1624569 A CH 1624569A CH 1624569 A CH1624569 A CH 1624569A CH 521972 A CH521972 A CH 521972A
- Authority
- CH
- Switzerland
- Prior art keywords
- quinazolinones
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
- C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Priority Applications (19)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH187472A CH520687A (de) | 1968-11-12 | 1969-10-31 | Verfahren zur Herstellung neuer 2(1H)-Chinazolinone |
CH187872A CH520691A (de) | 1968-11-12 | 1969-10-31 | Verfahren zur Herstellung von 2(1H)-Chinazolinonen |
CH187772A CH520690A (de) | 1968-11-12 | 1969-10-31 | Verfahren zur Herstellung von 2(1H)-Chinazolinonen |
CH187672A CH520689A (de) | 1969-10-31 | 1969-10-31 | Verfahren zur Herstellung neuer 2(1H)-Chinazolinone |
CH187572A CH520688A (de) | 1968-11-12 | 1969-10-31 | Verfahren zur Herstellung neuer 2(1H)-Chinazolinone |
CH187272A CH520145A (de) | 1968-11-12 | 1969-10-31 | Verfahren zur Herstellung von 2(1H)-Chinazolinonen |
CH187372A CH520686A (de) | 1968-11-12 | 1969-10-31 | Verfahren zur Herstellung neuer 2(1H)-Chinazolinone |
CH187972A CH520692A (de) | 1969-10-31 | 1969-10-31 | Verfahren zur Herstellung von 2(1H)-Chinazolinonen |
ES387033A ES387033A1 (es) | 1968-11-12 | 1971-01-05 | Procedimiento para la obtencion de quinazolinonas. |
ES387031A ES387031A1 (es) | 1968-11-12 | 1971-01-05 | Procedimiento para la obtencion de derivados de quinazoli- nonas. |
ES387032A ES387032A1 (es) | 1968-11-12 | 1971-01-05 | Procedimiento para la obtencion de derivados de quinazoli- nonas. |
ES387030A ES387030A1 (es) | 1968-11-12 | 1971-01-05 | Procedimiento para la obtencion de derivados de quinazoli- nonas. |
ES387027A ES387027A1 (es) | 1968-11-12 | 1971-01-05 | Procedimiento para la obtencion de derivados de quinazoli- nonas. |
ES387025A ES387025A1 (es) | 1968-11-12 | 1971-01-05 | Procedimiento para la obtencion de derivados de quinazoli- nonas. |
ES387026A ES387026A1 (es) | 1968-11-12 | 1971-01-05 | Procedimiento para la obtencion de derivados de quinazoli- nonas. |
ES387034A ES387034A1 (es) | 1968-11-12 | 1971-01-05 | Procedimiento para la obtencion de quinazolinonas. |
ES387024A ES387024A1 (es) | 1968-11-12 | 1971-01-05 | Procedimiento para la obtencion de derivados de quinazoli- nonas. |
ES387029A ES387029A1 (es) | 1968-11-12 | 1971-01-05 | Procedimiento para la obtencion de derivados de quinazoli- nonas. |
ES387028A ES387028A1 (es) | 1968-11-12 | 1971-01-05 | Procedimiento para la obtencion de derivados de quinazoli- nonas. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US00775201A US3723432A (en) | 1968-11-12 | 1968-11-12 | 1-substituted-4-aryl-2(1h)-quinazolinones and their preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
CH521972A true CH521972A (de) | 1972-04-30 |
Family
ID=25103642
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CH1624569A CH521972A (de) | 1968-11-12 | 1969-10-31 | Verfahren zur Herstellung von 2(1H)-Chinazolinonen |
Country Status (19)
Country | Link |
---|---|
US (2) | US3723432A (de) |
AT (4) | AT319950B (de) |
BE (1) | BE741529A (de) |
BG (10) | BG16042A3 (de) |
BR (1) | BR6914095D0 (de) |
CH (1) | CH521972A (de) |
DE (1) | DE1956384C3 (de) |
DK (1) | DK129347B (de) |
ES (1) | ES373377A1 (de) |
FR (1) | FR2024830B1 (de) |
GB (1) | GB1282612A (de) |
IE (1) | IE33933B1 (de) |
IL (1) | IL33348A (de) |
NL (1) | NL6916514A (de) |
NO (1) | NO124032B (de) |
OA (1) | OA03829A (de) |
PL (1) | PL72695B1 (de) |
SE (2) | SE374920B (de) |
ZA (1) | ZA697910B (de) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3923803A (en) * | 1968-07-18 | 1975-12-02 | Sumitomo Chemical Co | 2(1H)-Quinozalinones and process therefor |
US3642791A (en) * | 1969-08-13 | 1972-02-15 | Sandoz Ag | Morpholino-1-substituted-2(1h)-quinazolinones |
US4208343A (en) * | 1970-10-30 | 1980-06-17 | Westinghouse Electric Corp. | 2,4 Diamino benzonitrile |
BE785937A (fr) * | 1971-07-08 | 1973-01-08 | Sandoz Sa | Nouveaux derives de la quinazoline, leur preparation et leur application comme medicaments |
US3937705A (en) * | 1972-03-09 | 1976-02-10 | Sandoz, Inc. | 1-isopropyl-7-methyl-4-(p-fluorophenyl)-2(1h)-quinazolinone |
US4071516A (en) * | 1976-08-20 | 1978-01-31 | Sandoz, Inc. | 4-(Acyloxyphenyl)-quinazolin-2(1H)-ones |
US4064246A (en) * | 1976-10-12 | 1977-12-20 | Sandoz, Inc. | Hydroxymethyl-substituted-2(1H)-quinazolinones |
US4160092A (en) * | 1977-06-16 | 1979-07-03 | E. I. Du Pont De Nemours And Company | Quinazolinone oxides and their use as intermediates for pharmaceutical agents |
US4224328A (en) * | 1979-04-11 | 1980-09-23 | Sandoz, Inc. | Methods with 1-substituted-4-aryl-quinazolin-2(1H)-ones and thiones and pyrido[2,3-d]pyrimidin-2-ones as platelet aggregation inhibitors |
CH645362A5 (de) * | 1979-07-05 | 1984-09-28 | Sandoz Ag | Verfahren zur herstellung von 4-phenyl-2(1h)-chinazolinonen. |
FR2676042B1 (fr) * | 1991-05-02 | 1993-07-23 | Commissariat Energie Atomique | Procede de preparation d'un borohydrure de metal alcalin tel que le borohydrure de lithium. |
US6545004B1 (en) | 1999-10-27 | 2003-04-08 | Cytokinetics, Inc. | Methods and compositions utilizing quinazolinones |
US7230000B1 (en) | 1999-10-27 | 2007-06-12 | Cytokinetics, Incorporated | Methods and compositions utilizing quinazolinones |
AR038658A1 (es) | 2001-06-15 | 2005-01-26 | Novartis Ag | Derivados de 4-aril-2(1h) quinazolinona y 4-aril-quinazolina 2-sustituidas, un proceso para su preparacion, composiciones farmaceuticas y el uso de dichos derivados para la preparacion de un medicamento |
WO2003043995A1 (en) * | 2001-11-20 | 2003-05-30 | Cytokinetics, Inc. | Process for the racemization of chiral quinazolinones |
JP2005529076A (ja) * | 2002-02-15 | 2005-09-29 | サイトキネティクス・インコーポレーテッド | キナゾリノンの合成 |
MXPA04011074A (es) * | 2002-05-09 | 2005-06-08 | Cytokinetics Inc | Compuestos de pirimidinona, composiciones y metodos. |
AU2003270015A1 (en) | 2002-05-09 | 2003-12-02 | Cytokinetics, Inc. | Compounds, compositions, and methods |
EP1513820A4 (de) * | 2002-05-23 | 2006-09-13 | Cytokinetics Inc | Verbindungen, zusammensetzungen und verfahren |
AU2003236527A1 (en) * | 2002-06-14 | 2003-12-31 | Cytokinetics, Inc. | Compounds, compositions, and methods |
US7211580B2 (en) * | 2002-07-23 | 2007-05-01 | Cytokinetics, Incorporated | Compounds, compositions, and methods |
JP2005536553A (ja) * | 2002-08-21 | 2005-12-02 | サイトキネティクス・インコーポレーテッド | 化合物、組成物および方法 |
WO2004034972A2 (en) * | 2002-09-30 | 2004-04-29 | Cytokinetics, Inc. | Compounds, compositions, and methods |
GB0230015D0 (en) * | 2002-12-23 | 2003-01-29 | Novartis Ag | Organic compounds |
US7439241B2 (en) * | 2003-05-27 | 2008-10-21 | Galderma Laboratories, Inc. | Compounds, formulations, and methods for treating or preventing rosacea |
US8410102B2 (en) | 2003-05-27 | 2013-04-02 | Galderma Laboratories Inc. | Methods and compositions for treating or preventing erythema |
US20050197327A1 (en) * | 2003-11-03 | 2005-09-08 | Gustave Bergnes | Compounds, compositions, and methods |
US20050148593A1 (en) * | 2003-11-07 | 2005-07-07 | Gustave Bergnes | Compounds, compositions, and methods |
US7439254B2 (en) * | 2003-12-08 | 2008-10-21 | Cytokinetics, Inc. | Compounds, compositions, and methods |
KR20100024494A (ko) * | 2007-06-22 | 2010-03-05 | 아르퀼 인코포레이티드 | 퀴나졸리논 화합물 및 이의 사용 방법 |
US8058469B2 (en) * | 2008-11-03 | 2011-11-15 | Sabic Innovative Plastics Ip B.V. | Method for making carbamates, ureas and isocyanates |
EP2329849B1 (de) | 2009-11-18 | 2015-04-29 | Galderma Research & Development | Kombination aus einem Alpha-2-Adrenozeptor-Agonisten und einem nichtsteroidalen entzündungshemmenden Mittel zur Behandlung oder Prävention einer Entzündungskrankheit der Haut |
US8394800B2 (en) | 2009-11-19 | 2013-03-12 | Galderma Laboratories, L.P. | Method for treating psoriasis |
BR112012024476A2 (pt) | 2010-03-26 | 2017-03-01 | Galderma Res & Dev | método para fornecer um tratamento seguro e efetivo da telangiectasia e método de produzir um produto embalado |
AU2011231543B2 (en) | 2010-03-26 | 2015-01-15 | Galderma Research & Development | Improved methods and compositions for safe and effective treatment of erythema |
US8053427B1 (en) | 2010-10-21 | 2011-11-08 | Galderma R&D SNC | Brimonidine gel composition |
RU2571277C2 (ru) | 2010-10-21 | 2015-12-20 | Галдерма С.А. | Композиции геля с бримонидином и способы применения |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3452041A (en) * | 1965-05-19 | 1969-06-24 | American Home Prod | Hydantoin compounds and methods of preparation |
-
1968
- 1968-11-12 US US00775201A patent/US3723432A/en not_active Expired - Lifetime
- 1968-11-12 BG BG015055A patent/BG16042A3/bg unknown
-
1969
- 1969-10-31 GB GB53620/69A patent/GB1282612A/en not_active Expired
- 1969-10-31 CH CH1624569A patent/CH521972A/de not_active IP Right Cessation
- 1969-11-03 NL NL6916514A patent/NL6916514A/xx not_active Application Discontinuation
- 1969-11-07 FR FR696938404A patent/FR2024830B1/fr not_active Expired
- 1969-11-10 BG BG014695A patent/BG16039A3/bg unknown
- 1969-11-10 BE BE741529A patent/BE741529A/xx unknown
- 1969-11-10 AT AT993271A patent/AT319950B/de not_active IP Right Cessation
- 1969-11-10 BG BG013325A patent/BG16188A3/bg unknown
- 1969-11-10 BG BG015469A patent/BG16043A3/bg unknown
- 1969-11-10 NO NO4445/69A patent/NO124032B/no unknown
- 1969-11-10 AT AT993571A patent/AT310176B/de not_active IP Right Cessation
- 1969-11-10 DE DE1956384A patent/DE1956384C3/de not_active Expired
- 1969-11-10 BG BG014696A patent/BG16040A3/bg unknown
- 1969-11-10 ES ES373377A patent/ES373377A1/es not_active Expired
- 1969-11-10 BG BG014692A patent/BG16036A3/bg unknown
- 1969-11-10 AT AT1053269A patent/AT310169B/de not_active IP Right Cessation
- 1969-11-10 BG BG014693A patent/BG16037A3/bg unknown
- 1969-11-10 BG BG014694A patent/BG16038A3/bg unknown
- 1969-11-10 IE IE1526/69A patent/IE33933B1/xx unknown
- 1969-11-10 AT AT993071A patent/AT319949B/de not_active IP Right Cessation
- 1969-11-10 OA OA53783A patent/OA03829A/xx unknown
- 1969-11-11 IL IL33348A patent/IL33348A/xx unknown
- 1969-11-11 SE SE6915448A patent/SE374920B/xx unknown
- 1969-11-11 DK DK597169AA patent/DK129347B/da unknown
- 1969-11-11 SE SE7213438A patent/SE376917B/xx unknown
- 1969-11-11 BR BR214095/69A patent/BR6914095D0/pt unknown
- 1969-11-12 PL PL1969136872A patent/PL72695B1/pl unknown
- 1969-11-12 ZA ZA697910A patent/ZA697910B/xx unknown
-
1970
- 1970-05-16 BG BG014697A patent/BG16041A3/bg unknown
- 1970-08-13 BG BG015468A patent/BG15573A3/bg unknown
-
1972
- 1972-12-08 US US313531A patent/US3925548A/en not_active Expired - Lifetime
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PL | Patent ceased |