PL357555A1 - Pyrimidine carboxamides useful as inhibitors of pde4 isozymes - Google Patents

Pyrimidine carboxamides useful as inhibitors of pde4 isozymes

Info

Publication number
PL357555A1
PL357555A1 PL01357555A PL35755501A PL357555A1 PL 357555 A1 PL357555 A1 PL 357555A1 PL 01357555 A PL01357555 A PL 01357555A PL 35755501 A PL35755501 A PL 35755501A PL 357555 A1 PL357555 A1 PL 357555A1
Authority
PL
Poland
Prior art keywords
inhibitors
chronic
pde4 isozymes
carboxamides useful
pyrimidine carboxamides
Prior art date
Application number
PL01357555A
Other languages
English (en)
Polish (pl)
Inventor
Robert James Chambers
Thomas Victor Magee
Anthony Marfat
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of PL357555A1 publication Critical patent/PL357555A1/xx

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/34—One oxygen atom
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    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
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    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
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    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
PL01357555A 2000-01-31 2001-01-30 Pyrimidine carboxamides useful as inhibitors of pde4 isozymes PL357555A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17928200P 2000-01-31 2000-01-31
PCT/IB2001/000125 WO2001057025A1 (en) 2000-01-31 2001-01-30 Pyrimidine carboxamides useful as inhibitors of pde4 isozymes

Publications (1)

Publication Number Publication Date
PL357555A1 true PL357555A1 (en) 2004-07-26

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PL01357555A PL357555A1 (en) 2000-01-31 2001-01-30 Pyrimidine carboxamides useful as inhibitors of pde4 isozymes

Country Status (44)

Country Link
US (1) US6740655B2 (en, 2012)
EP (1) EP1252157B1 (en, 2012)
JP (1) JP2003522165A (en, 2012)
KR (1) KR20020071029A (en, 2012)
CN (1) CN1404480A (en, 2012)
AP (1) AP2002002590A0 (en, 2012)
AR (1) AR027336A1 (en, 2012)
AT (1) ATE269860T1 (en, 2012)
AU (1) AU2700301A (en, 2012)
BG (1) BG106868A (en, 2012)
BR (1) BR0107934A (en, 2012)
CA (1) CA2396458C (en, 2012)
CO (1) CO5271669A1 (en, 2012)
CR (1) CR6714A (en, 2012)
CZ (1) CZ20022413A3 (en, 2012)
DE (1) DE60103976T2 (en, 2012)
DK (1) DK1252157T3 (en, 2012)
DZ (1) DZ3406A1 (en, 2012)
EA (1) EA005028B1 (en, 2012)
EE (1) EE200200426A (en, 2012)
ES (1) ES2223772T3 (en, 2012)
GE (1) GEP20043385B (en, 2012)
GT (1) GT200100023A (en, 2012)
HK (1) HK1054232A1 (en, 2012)
HN (1) HN2001000018A (en, 2012)
HU (1) HUP0204271A3 (en, 2012)
IL (1) IL150486A0 (en, 2012)
IS (1) IS6444A (en, 2012)
MA (1) MA26871A1 (en, 2012)
MX (1) MXPA02007465A (en, 2012)
NO (1) NO20023614L (en, 2012)
NZ (1) NZ519726A (en, 2012)
OA (1) OA12170A (en, 2012)
PA (1) PA8511301A1 (en, 2012)
PE (1) PE20011059A1 (en, 2012)
PL (1) PL357555A1 (en, 2012)
PT (1) PT1252157E (en, 2012)
SK (1) SK10342002A3 (en, 2012)
SV (1) SV2001000298A (en, 2012)
TN (1) TNSN01019A1 (en, 2012)
TR (1) TR200402292T4 (en, 2012)
UY (1) UY26570A1 (en, 2012)
WO (1) WO2001057025A1 (en, 2012)
ZA (1) ZA200206034B (en, 2012)

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ES2165768B1 (es) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
US20030032632A1 (en) * 1999-12-24 2003-02-13 Crispps Leslie Alan Pharmaceutical aerosol formulation of salmeterol and fluticasone propionate
DE10110772A1 (de) * 2001-03-07 2002-09-12 Boehringer Ingelheim Pharma Neue Arzneimittelkompositionen auf der Basis von Anticholinergika und PDE-IV-Inhibitoren
US7776315B2 (en) 2000-10-31 2010-08-17 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pharmaceutical compositions based on anticholinergics and additional active ingredients
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