PL2265709T3 - Mikroorganizmy do produkcji kwasu adypinowego i innych związków - Google Patents

Mikroorganizmy do produkcji kwasu adypinowego i innych związków

Info

Publication number
PL2265709T3
PL2265709T3 PL09763021T PL09763021T PL2265709T3 PL 2265709 T3 PL2265709 T3 PL 2265709T3 PL 09763021 T PL09763021 T PL 09763021T PL 09763021 T PL09763021 T PL 09763021T PL 2265709 T3 PL2265709 T3 PL 2265709T3
Authority
PL
Poland
Prior art keywords
microorganisms
compounds
production
adipic acid
adipic
Prior art date
Application number
PL09763021T
Other languages
English (en)
Inventor
Anthony P. Burgard
Priti Pharkya
Robin E. Osterhout
Original Assignee
Genomatica, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genomatica, Inc. filed Critical Genomatica, Inc.
Publication of PL2265709T3 publication Critical patent/PL2265709T3/pl

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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0006Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1025Acyltransferases (2.3)
    • C12N9/1029Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1096Transferases (2.) transferring nitrogenous groups (2.6)
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/78Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
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    • C12N9/88Lyases (4.)
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    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/005Amino acids other than alpha- or beta amino acids, e.g. gamma amino acids
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    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/02Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
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    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10Nitrogen as only ring hetero atom
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    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44Polycarboxylic acids
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    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44Polycarboxylic acids
    • C12P7/46Dicarboxylic acids having four or less carbon atoms, e.g. fumaric acid, maleic acid
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    • C12P7/62Carboxylic acid esters
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    • C12YENZYMES
    • C12Y103/00Oxidoreductases acting on the CH-CH group of donors (1.3)
    • C12Y103/01Oxidoreductases acting on the CH-CH group of donors (1.3) with NAD+ or NADP+ as acceptor (1.3.1)
    • C12Y103/010312-Enoate reductase (1.3.1.31)
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    • C12Y101/00Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/010353-Hydroxyacyl-CoA dehydrogenase (1.1.1.35)
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    • C12Y102/00Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/01Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
    • C12Y102/0101Acetaldehyde dehydrogenase (acetylating) (1.2.1.10)
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    • C12Y206/00Transferases transferring nitrogenous groups (2.6)
    • C12Y206/01Transaminases (2.6.1)
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    • C12Y402/00Carbon-oxygen lyases (4.2)
    • C12Y402/01Hydro-lyases (4.2.1)

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  • Chemical & Material Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
PL09763021T 2008-03-27 2009-03-27 Mikroorganizmy do produkcji kwasu adypinowego i innych związków PL2265709T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4005908P 2008-03-27 2008-03-27
PCT/US2009/038663 WO2009151728A2 (en) 2008-03-27 2009-03-27 Microorganisms for the production of adipic acid and other compounds
EP09763021.4A EP2265709B1 (en) 2008-03-27 2009-03-27 Microorganisms for the production of adipic acid and other compounds

Publications (1)

Publication Number Publication Date
PL2265709T3 true PL2265709T3 (pl) 2018-05-30

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PL09763021T PL2265709T3 (pl) 2008-03-27 2009-03-27 Mikroorganizmy do produkcji kwasu adypinowego i innych związków

Country Status (14)

Country Link
US (11) US7799545B2 (pl)
EP (2) EP2265709B1 (pl)
JP (6) JP5951990B2 (pl)
CN (4) CN102066551B (pl)
BR (1) BRPI0910928A2 (pl)
CA (3) CA2719679C (pl)
DK (1) DK2265709T3 (pl)
ES (1) ES2656790T3 (pl)
HU (1) HUE035611T2 (pl)
LT (1) LT2265709T (pl)
NO (1) NO2265709T3 (pl)
PL (1) PL2265709T3 (pl)
SI (1) SI2265709T1 (pl)
WO (1) WO2009151728A2 (pl)

Families Citing this family (142)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8673601B2 (en) 2007-01-22 2014-03-18 Genomatica, Inc. Methods and organisms for growth-coupled production of 3-hydroxypropionic acid
WO2009045637A2 (en) 2007-08-10 2009-04-09 Genomatica, Inc. Methods for the synthesis of acrylic acid and derivatives from fumaric acid
WO2009094485A1 (en) 2008-01-22 2009-07-30 Genomatica, Inc. Methods and organisms for utilizing synthesis gas or other gaseous carbon sources and methanol
CA2717586C (en) 2008-03-05 2020-08-11 Genomatica, Inc. Primary alcohol producing organisms
NO2252698T3 (pl) 2008-03-11 2018-04-21
CN102066551B (zh) 2008-03-27 2013-10-09 基因组股份公司 用于产生己二酸和其他化合物的微生物
US8241877B2 (en) * 2008-05-01 2012-08-14 Genomatica, Inc. Microorganisms for the production of methacrylic acid
BRPI0913901A2 (pt) 2008-06-17 2016-12-13 Genomatica Inc micro-organismos e métodos para a biossíntese de fumarato, malato e acrilato
WO2010057022A1 (en) * 2008-11-14 2010-05-20 Genomatica, Inc. Microorganisms for the production of methyl ethyl ketone and 2-butanol
BRPI0922944A2 (pt) 2008-12-12 2015-08-25 Celexion Llc Célula hospedeira projetada metabolicamente para a produção de um alcano, contendo uma ou mais sequências de ácido nucleico exógeno e método para produzir um alcano
WO2010071697A1 (en) 2008-12-16 2010-06-24 Genomatica, Inc. Microorganisms and methods for conversion of syngas and other carbon sources to useful products
EP2210935A1 (en) * 2009-01-19 2010-07-28 Deinove Methods for isolating bacteria
US8404465B2 (en) 2009-03-11 2013-03-26 Celexion, Llc Biological synthesis of 6-aminocaproic acid from carbohydrate feedstocks
EP3318626B1 (en) 2009-04-30 2020-01-15 Genomatica, Inc. Organisms for the production of 1,3-butanediol
WO2010127303A1 (en) 2009-04-30 2010-11-04 Genomatica, Inc. Organisms for the production of isopropanol, n-butanol, and isobutanol
BRPI1011227A8 (pt) 2009-05-07 2019-02-26 Genomatica Inc microorganismos e métodos para a biossíntese de adipato, hexametilenodiamina e ácido 6-aminocapróico.
BRPI1012877A2 (pt) 2009-05-15 2016-04-05 Genomatica Inc organismo para produção de ciclohexanona
EP2440669A4 (en) 2009-06-10 2013-08-28 Genomatica Inc MICROOGANISMS AND PROCEDURES FOR THE CARBON EFFECTIVE BIOSYNTHESIS MEK AND 2-BUTANOL
US8669397B2 (en) 2009-06-13 2014-03-11 Rennovia, Inc. Production of adipic acid and derivatives from carbohydrate-containing materials
BRPI1010708B1 (pt) 2009-06-13 2018-04-03 Rennovia, Inc. "processos para preparar um produto de ácido adípico, e ácido adípico ou derivado do mesmo"
NZ596974A (en) 2009-06-13 2014-03-28 Rennovia Inc Production of glutaric acid and derivatives from carbohydrate-containing materials
US20120156761A1 (en) 2009-07-02 2012-06-21 Verdezyne, Inc. Biological methods for preparing adipic acid
EP2462221B1 (en) 2009-08-05 2017-02-22 Genomatica, Inc. Semi-synthetic terephthalic acid via microorganisms that produce muconic acid
EP2933338A3 (en) 2009-09-09 2016-01-06 Genomatica, Inc. Microorganisms and methods for the co-production of isopropanol with primary alcohols, diols and acids
CN105441374A (zh) 2009-10-13 2016-03-30 基因组股份公司 生产1,4-丁二醇、4-羟基丁醛、4-羟基丁酰-coa、腐胺和相关化合物的微生物及其相关方法
WO2011050326A1 (en) 2009-10-23 2011-04-28 Genomatica, Inc. Microorganisms for the production of aniline
EP2510102A4 (en) 2009-12-10 2014-01-22 Genomatica Inc METHODS AND ORGANIZATIONS FOR THE CONVERSION OF SYNTHESIS GAS OR OTHER CARBONACEOUS GAS SOURCES AND METHANOL TO 1,3-BUTANEDIOL
SG182686A1 (en) 2010-01-29 2012-08-30 Genomatica Inc Microorganisms and methods for the biosynthesis of p-toluate and terephthalate
US8048661B2 (en) 2010-02-23 2011-11-01 Genomatica, Inc. Microbial organisms comprising exogenous nucleic acids encoding reductive TCA pathway enzymes
US8445244B2 (en) 2010-02-23 2013-05-21 Genomatica, Inc. Methods for increasing product yields
US8669393B2 (en) 2010-03-05 2014-03-11 Rennovia, Inc. Adipic acid compositions
US9023636B2 (en) 2010-04-30 2015-05-05 Genomatica, Inc. Microorganisms and methods for the biosynthesis of propylene
US20110269993A1 (en) 2010-04-30 2011-11-03 Bioamber S.A.S. Processes for producing adipic acid from fermentation broths containing diammonium adipate
US8895779B2 (en) 2010-04-30 2014-11-25 Bioamber Inc. Processes for producing monoammonium adipate and conversion of monoammonium adipate to adipic acid
US8580543B2 (en) 2010-05-05 2013-11-12 Genomatica, Inc. Microorganisms and methods for the biosynthesis of butadiene
US9770705B2 (en) 2010-06-11 2017-09-26 Rennovia Inc. Oxidation catalysts
JP2013530184A (ja) 2010-06-16 2013-07-25 ビオアンブ,ソシエテ パ アクシオンス シンプリフィエ ヘキサメチレンジアミン(hmd)、アジポニトリル(adn)、アジパミド(adm)及びそれらの誘導体の製造方法
BR112012031877A2 (pt) 2010-06-16 2015-09-22 Bioamber Sas processo para produzir caprolactam e derivados do mesmo de caldos de fermentação contendo adipato de diamônio ou adipato de monomônio.
CN103140467A (zh) 2010-06-16 2013-06-05 生物琥珀酸有限公司 己二胺(hmd)、己二腈(adn)、己二酰胺(adm)及其衍生物的制备方法
BR112012031818A2 (pt) 2010-06-16 2019-09-24 Bioamber Sas processos para a produção de produtos hidrogenados e derivados dos mesmos.
CA2800291A1 (en) 2010-06-16 2011-12-22 Bioamber S.A.S. Processes for producing caprolactam and derivatives thereof from fermentation broths containing diammonium adipate, monoammonium adipate and/or adipic acid
BR112012031822A2 (pt) * 2010-06-16 2015-09-22 Bioamber Sas processos para a produção de produtos hidrogenados e seus derivados.
WO2012018624A2 (en) 2010-07-26 2012-02-09 Genomatica, Inc. Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene
CA2807561C (en) 2010-08-06 2022-04-12 Mascoma Corporation Production of malonyl-coa derived products via anaerobic pathways
BR112013023848A2 (pt) * 2011-03-18 2018-07-03 Mitsubishi Chem Corp método para produzir polímero, método para produzir ácido orgânico, e microrganismo produtor de ácido orgânico.
WO2012137771A1 (ja) * 2011-04-08 2012-10-11 昭和電工株式会社 アジピン酸の製造方法
US8343752B2 (en) 2011-05-03 2013-01-01 Verdezyne, Inc. Biological methods for preparing adipic acid
US8728798B2 (en) 2011-05-03 2014-05-20 Verdezyne, Inc. Biological methods for preparing adipic acid
WO2012156151A1 (en) * 2011-05-16 2012-11-22 Evonik Degussa Gmbh METHOD FOR ω-AMINOCARBOXYLIC ACID CONDENSATION
WO2012170060A1 (en) 2011-06-10 2012-12-13 Bioamber S.A.S. Processes for producing hexanediol (hdo), hexamethylenediamine (hmd), and derivatives thereof
US8852899B2 (en) * 2011-06-17 2014-10-07 Invista North America S.A.R.L. Methods of making nylon intermediates from glycerol
CN105969813A (zh) 2011-06-17 2016-09-28 英威达技术有限责任公司 使用水解酶来增加废物流中的单体含量
EP2726627A2 (en) 2011-06-30 2014-05-07 Invista Technologies S.à.r.l. Bioconversion process for producing nylon-7, nylon-7,7 and polyesters
WO2013067432A1 (en) 2011-11-02 2013-05-10 Genomatica, Inc. Microorganisms and methods for the production of caprolactone
CN104220601A (zh) * 2011-12-16 2014-12-17 英威达技术有限责任公司 经与碳储存相关的CoA 依赖性碳链延长制备6 碳化学品的方法
US9102960B2 (en) 2011-12-16 2015-08-11 Invista North America S.á.r.l. Methods of producing 6-carbon chemicals via CoA-dependent carbon chain elongation associated with carbon storage
US9102958B2 (en) 2011-12-16 2015-08-11 Invista North America S.á.r.l. Methods of producing 6-carbon chemicals via CoA-dependent carbon chain elongation associated with carbon storage
VN39714A1 (en) 2011-12-23 2014-10-27 Purac Biochem Bv Polycarboxylic acid extraction
US10683520B2 (en) * 2011-12-23 2020-06-16 Purac Biochem Bv Polycarboxylic acid extraction
EP2820141B1 (en) * 2012-02-29 2018-04-11 Duke University Novel oxidoreductases for enantioselective reactions
US9155139B2 (en) 2012-03-09 2015-10-06 Rockwell Automation Technologies, Inc. LED driver circuits and methods
US9803209B2 (en) 2012-05-18 2017-10-31 Novozymes A/S Bacterial mutants with improved transformation efficiency
CN103484490B (zh) * 2012-06-12 2015-10-28 中国科学院过程工程研究所 用于生产己二酸的重组质粒、基因工程菌、其制备方法及用途
WO2014043182A2 (en) * 2012-09-14 2014-03-20 Bioamber Inc. Alternative pathways to adipates and adipic acid by combined fermentation and catalytic methods
US9528133B2 (en) 2012-09-21 2016-12-27 Synthetic Genomics, Inc. Compositions and methods for producing chemicals and derivatives thereof
EP2898083A4 (en) 2012-09-21 2016-05-25 Synthetic Genomics Inc COMPOSITIONS AND PROCESSES FOR THE PRODUCTION OF CHEMICALS AND THEIR DERIVATIVES
EP2900689B1 (en) 2012-09-27 2017-08-02 Novozymes, Inc. Bacterial mutants with improved transformation efficiency
US9790525B2 (en) 2012-12-14 2017-10-17 Invista North America S.A.R.L. Methods of producing 7-carbon chemicals via CoA-dependent carbon chain elongation associated with carbon storage
WO2014099725A1 (en) * 2012-12-17 2014-06-26 Genomatica, Inc. Microorganisms and methods for enhancing the availability of reducing equivalents in the presence of methanol, and for producing adipate, 6-aminocaproate, hexamethylenediamine or caprolactam related thereto
WO2014105790A2 (en) 2012-12-31 2014-07-03 Invista North America S.A.R.L. Methods of producing 7-carbon chemicals via c1 carbon chain elongation associated with coenzyme b synthesis
CN105026570A (zh) 2012-12-31 2015-11-04 英威达技术有限责任公司 通过氧化裂解从长链脂肪酸生产7-碳化学物的方法
WO2014105788A2 (en) 2012-12-31 2014-07-03 Invista North America S.A.R.L. Methods of producing 7-carbon chemicals via carbon chain elongation associated with cyclohexane carboxylate synthesis
US9580733B2 (en) 2012-12-31 2017-02-28 Invista North America S.A.R.L. Methods of producing 6-carbon chemicals via methyl-ester shielded carbon chain elongation
EP2938733A2 (en) 2012-12-31 2015-11-04 Invista North America S.a.r.l. Methods of producing 7-carbon chemicals via methyl-ester shielded carbon chain elongation
US9617572B2 (en) 2012-12-31 2017-04-11 Invista North America S.A.R.L. Methods of producing 7-carbon chemicals via aromatic compounds
CN105026569A (zh) 2012-12-31 2015-11-04 英威达技术有限责任公司 通过丙酮酸和琥珀酸半醛羟醛缩合生产7-碳化学物的方法
WO2014145194A2 (en) 2013-03-15 2014-09-18 Kiverdi, Inc. Methods of using natural and engineered organisms to produce small molecules for industrial application
EP2971021A4 (en) 2013-03-15 2016-12-21 Genomatica Inc MICROORGANISMS AND METHOD FOR THE PRODUCTION OF BUTADIENE AND RELATED COMPOUNDS BY FORMATASSIMILATION
KR101609448B1 (ko) 2013-05-06 2016-04-05 한국생명공학연구원 6-아미노카프로산의 생물학적 합성 및 이를 위한 형질전환 미생물
WO2014182016A1 (ko) * 2013-05-06 2014-11-13 한국생명공학연구원 6-아미노카프로산의 생물학적 합성 및 이를 위한 형질전환 미생물
KR101513482B1 (ko) * 2013-06-17 2015-04-20 고려대학교 산학협력단 새로운 아디프산 합성 경로에 의한 아디프산 제조방법
JP6680671B2 (ja) * 2013-09-17 2020-04-15 ズィモケム インコーポレイテッドZymochem Inc. 再生可能資源から化合物を生成するための高収量経路
US12104160B2 (en) 2013-09-17 2024-10-01 Zymochem, Inc. Production of 4,6-dihydroxy-2-oxo-hexanoic acid
PL3077501T3 (pl) 2013-12-03 2022-01-31 Genomatica, Inc. Mikroorganizmy i sposoby poprawy wydajności produktu na metanolu z użyciem syntezy acetylo-coa
ES2800606T3 (es) 2013-12-27 2021-01-04 Genomatica Inc Métodos y organismos con mayores eficiencias del flujo de carbono
CN103937841B (zh) * 2014-05-13 2015-10-28 上海交通大学 烯酰辅酶a水合酶在己二酸生物合成中的应用
WO2015176026A1 (en) 2014-05-15 2015-11-19 Invista North America S.á.r.l. Methods of producing 6-carbon chemicals using 2,6-diaminopimelate as precursor to 2-aminopimelate
EP3155105A1 (en) * 2014-06-16 2017-04-19 Invista Technologies S.A R.L. Methods, reagents and cells for biosynthesizing compounds
BR112016029375A2 (pt) 2014-06-16 2017-10-17 Invista Tech Sarl métodos, reagentes e células para biossintetizar compostos
WO2015195710A1 (en) 2014-06-16 2015-12-23 Invista Technlogies S.A.R.L. Process for producing glutarate and glutaric acid methyl ester
CN106795537A (zh) 2014-06-16 2017-05-31 英威达技术有限责任公司 用于生物合成化合物的方法、试剂和细胞
KR20160008883A (ko) 2014-07-15 2016-01-25 서울대학교산학협력단 아미노카프로익산으로부터 두 단계 효소 반응을 통한 아디프산의 생산
DK3194604T3 (da) 2014-09-18 2020-05-25 Genomatica Inc Ikke-naturlig mikrobielle organismer med forbedret energisk effektivitet
WO2016048048A1 (ko) * 2014-09-23 2016-03-31 한국생명공학연구원 신규 카프로락탐 전환 효소를 이용한 ε-카프로락탐의 제조 방법
US9459201B2 (en) 2014-09-29 2016-10-04 Zyomed Corp. Systems and methods for noninvasive blood glucose and other analyte detection and measurement using collision computing
US10490300B2 (en) 2015-01-05 2019-11-26 Samsung Electronics Co., Ltd. Methods and apparatus for assessing pathways for bio-chemical synthesis
KR101715882B1 (ko) 2015-03-06 2017-03-27 한국생명공학연구원 신규 ε-카프로락탐 전환 효소 및 이를 이용한 ε-카프로락탐 생산 방법
WO2016167519A1 (ko) * 2015-04-13 2016-10-20 한국과학기술원 락탐의 제조방법
KR101839595B1 (ko) 2015-04-13 2018-04-26 한국과학기술원 락탐의 제조방법
EP3309258B1 (en) * 2015-06-10 2020-06-03 Toray Industries, Inc. Method for producing 3-hydroxyadipic acid
JP6907537B2 (ja) * 2015-06-10 2021-07-21 東レ株式会社 α−ヒドロムコン酸の製造方法
CN105112436B (zh) * 2015-06-29 2018-08-28 江南大学 一种己二酸的全生物合成方法
CA2897454C (en) 2015-07-03 2023-03-14 Governing Council Of The University Of Toronto Microorganisms and methods for biosynthesis of adipic acid
US10435693B2 (en) 2015-08-31 2019-10-08 Alliance For Sustainable Energy, Llc Organic acid synthesis from C1 substrates
CA2998303A1 (en) 2015-09-11 2017-03-16 Toray Industries, Inc. Method for producing .sigma.-caprolactam
JP6905518B2 (ja) * 2015-10-13 2021-07-21 ランザテク・ニュージーランド・リミテッド エネルギー発生発酵経路を含む遺伝子操作細菌
US10793673B2 (en) 2015-11-10 2020-10-06 Iowa State University Research Foundation, Inc. Bioadvantaged nylon: polycondensation of 3-hexenedioic acid with hexamethylenediamine
ES2761328T3 (es) 2015-12-03 2020-05-19 Friedrich Miescher Institute For Biomedical Res SynP161, un promotor para la expresión específica de genes en fotorreceptores de bastón
EP3388525B1 (en) 2015-12-11 2020-09-16 Toray Industries, Inc. Method for producing 3-oxoadipic acid by fermentation
US10510434B2 (en) 2016-02-15 2019-12-17 Samsung Electronics Co., Ltd. Device and method of selecting pathway of target compound
US9554738B1 (en) 2016-03-30 2017-01-31 Zyomed Corp. Spectroscopic tomography systems and methods for noninvasive detection and measurement of analytes using collision computing
WO2017205750A1 (en) * 2016-05-26 2017-11-30 The Regents Of The University Of Michigan Compositions and methods for microbial co-culture
JP6948595B2 (ja) 2016-05-31 2021-10-13 東レ株式会社 α−ヒドロムコン酸の製造方法
WO2017209102A1 (ja) 2016-05-31 2017-12-07 東レ株式会社 3-ヒドロキシアジピン酸の製造方法
KR101971480B1 (ko) 2017-09-26 2019-04-23 한국생명공학연구원 돌연변이 재설계 유전자 회로를 이용한 니트릴계, 락톤계 또는 락탐계 화합물의 감지 및 정량 방법
MX2020005324A (es) * 2017-11-30 2020-08-13 Toray Industries Microorganismo modificado geneticamente para producir acido 3-hidroxidadipico, acido alfa-hidromuconico y/o acido adipico, y metodo de produccion para tales productos quimicos.
US20210079334A1 (en) 2018-01-30 2021-03-18 Genomatica, Inc. Fermentation systems and methods with substantially uniform volumetric uptake rate of a reactive gaseous component
US11541105B2 (en) 2018-06-01 2023-01-03 The Research Foundation For The State University Of New York Compositions and methods for disrupting biofilm formation and maintenance
WO2020171867A2 (en) * 2018-11-29 2020-08-27 Zymergen, Inc. Engineered biosynthetic pathways for production of 2-oxoadipate by fermentation
US12258610B2 (en) 2019-04-25 2025-03-25 Zymochem, Inc. Production of chemicals from renewable sources
JP7530554B2 (ja) * 2019-05-10 2024-08-08 東レ株式会社 3-ヒドロキシアジピン酸、α-ヒドロムコン酸および/またはアジピン酸を生産するための遺伝子改変微生物および当該化学品の製造方法
JP7646119B2 (ja) * 2019-05-10 2025-03-17 東レ株式会社 3-ヒドロキシアジピン酸、α-ヒドロムコン酸および/またはアジピン酸を生産するための遺伝子改変微生物および当該化学品の製造方法
EP3763848A1 (de) 2019-07-10 2021-01-13 Technische Universität Berlin Verfahren zur elektrodicarboxylierung von mindestens einem alken mit kohlendioxid co2 in gegenwart von wasserstoff h2
US11401910B2 (en) 2019-08-19 2022-08-02 Alliance For Sustainable Energy, Llc Flexible wave energy converter
CN110577973B (zh) * 2019-09-23 2022-06-14 山东大学 一种体外催化ω-氨基酸生产二元羧酸的方法
CN110713990B (zh) * 2019-10-21 2021-08-10 北京化工大学 一种烯酸还原酶的突变体蛋白及其应用
CN111484942A (zh) * 2019-12-02 2020-08-04 江南大学 一种利用酿酒酵母生产己二酸的方法
MX2022013570A (es) * 2020-04-29 2022-11-30 Lanzatech Inc Produccion fermentativa de b-cetoadipato a partir de sustratos gaseosos.
CN115551993B (zh) * 2020-05-12 2025-08-05 东丽株式会社 基因修饰微生物以及有机酸的制造方法
KR102507457B1 (ko) * 2020-08-24 2023-03-07 포항공과대학교 산학협력단 일산화탄소로부터 유기산을 고효율로 생산하기 위한 상호공생 미생물 컨소시엄을 포함하는 조성물 및 이를 이용한 방법
US20240254283A1 (en) * 2020-09-21 2024-08-01 Iowa State University Research Foundation, Inc. Base-catalyzed isomerization of muconic acid derivatives
US20230392112A1 (en) * 2020-11-11 2023-12-07 Toray Industries, Inc. Genetically modified microorganism for producing 3-hydroxyadipic acid and/or alpha-hydromuconic acid, and method for producing chemical product
WO2022155554A1 (en) 2021-01-17 2022-07-21 Genomatica, Inc. Methods and compositions for making amide compounds
JPWO2022181654A1 (pl) * 2021-02-25 2022-09-01
CN113046283B (zh) * 2021-03-01 2023-06-13 江南大学 一株通过还原tca途径生产己二酸的工程菌株及其构建方法
JP7038241B1 (ja) 2021-03-30 2022-03-17 旭化成株式会社 組換え微生物及びアジピン酸又はその誘導体の製造方法
JP7625070B2 (ja) * 2021-03-30 2025-01-31 旭化成株式会社 組換え微生物及びc6化合物の製造方法
JPWO2023182322A1 (pl) 2022-03-23 2023-09-28
KR102775099B1 (ko) * 2022-06-02 2025-03-04 한국화학연구원 증가된 아디프산 생산능을 갖는 재조합 미생물, 그를 포함하는 조성물 및 그를 이용하여 아디프산을 생산하는 방법
CN116083332B (zh) * 2022-12-26 2025-09-23 江南大学 一株产己二酸的重组大肠杆菌的构建及其应用
CN116904381B (zh) * 2023-07-31 2024-07-12 江南大学 一株产己二酸的重组大肠杆菌的构建及其应用
CN121380231A (zh) * 2025-12-24 2026-01-23 赤峰艾克制药科技股份有限公司 一种盐酸去氧肾上腺素的高效合成方法

Family Cites Families (165)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4076948A (en) 1968-10-10 1978-02-28 El Paso Products Company Process for treatment of adipic acid mother liquor
US3513209A (en) 1968-08-19 1970-05-19 Du Pont Method of making 1,4-cyclohexadiene
GB1230276A (pl) 1968-12-09 1971-04-28
US3965182A (en) 1969-10-02 1976-06-22 Ethyl Corporation Preparation of aniline from phenol and ammonia
JPS4831084B1 (pl) 1970-09-04 1973-09-26
GB1344557A (en) 1972-06-23 1974-01-23 Mitsubishi Petrochemical Co Process for preparing 1,4-butanediol
JPS5543759B2 (pl) 1972-06-28 1980-11-07
JPS506776A (pl) 1973-05-28 1975-01-23
DE2455617C3 (de) 1974-11-23 1982-03-18 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von Butandiol und/oder Tetrahydrofuran über die Zwischenstufe des γ-Butyrolactons
DE2501499A1 (de) 1975-01-16 1976-07-22 Hoechst Ag Verfahren zur herstellung von butandiol-(1.4)
US4190495A (en) 1976-09-27 1980-02-26 Research Corporation Modified microorganisms and method of preparing and using same
US4301077A (en) 1980-12-22 1981-11-17 Standard Oil Company Process for the manufacture of 1-4-butanediol and tetrahydrofuran
US4521516A (en) * 1982-11-18 1985-06-04 Cpc International Inc. Strain of Clostridium acetobutylicum and process for its preparation
JPS60114197A (ja) 1983-11-25 1985-06-20 Agency Of Ind Science & Technol 微生物によるジカルボン酸の製造法
US4871667A (en) 1984-11-26 1989-10-03 Agency Of Industrial Science & Technology Process for preparing muconic acid
US4652685A (en) 1985-11-15 1987-03-24 General Electric Company Hydrogenation of lactones to glycols
DE3602374A1 (de) * 1986-01-28 1987-07-30 Basf Ag Verfahren zur herstellung von 6-aminocapronsaeure
US5168055A (en) 1986-06-11 1992-12-01 Rathin Datta Fermentation and purification process for succinic acid
US5143834A (en) 1986-06-11 1992-09-01 Glassner David A Process for the production and purification of succinic acid
DE3783081T2 (de) 1986-06-11 1993-04-15 Michigan Biotech Inst Verfahren zur herstellung von bernsteinsaeure durch anaerobe fermentation.
US5182199A (en) 1987-05-27 1993-01-26 Hartley Brian S Thermophilic ethanol production in a two-stage closed system
DE68928956T2 (de) 1988-04-27 1999-07-29 Daicel Chemical Industries, Ltd., Sakai, Osaka Verfahren zur Herstellung von optisch aktivem 1,3-Butanediol
EP0470172B1 (en) 1989-04-27 1995-06-28 BioControl Systems, Incorporated Precipitate test for microorganisms
US5192673A (en) 1990-04-30 1993-03-09 Michigan Biotechnology Institute Mutant strain of C. acetobutylicum and process for making butanol
US5079143A (en) 1990-05-02 1992-01-07 The Upjohn Company Method of indentifying compounds useful as antiparasitic drugs
DE69126298T2 (de) 1990-10-15 1997-09-04 Daicel Chem Verfahren zur Herstellung optisch aktiven (R)-1,3-Butanediols mittels eines Mikroorganismus der Gattung Rhodococcus
US5173429A (en) 1990-11-09 1992-12-22 The Board Of Trustees Of The University Of Arkansas Clostridiumm ljungdahlii, an anaerobic ethanol and acetate producing microorganism
IL100572A (en) 1991-01-03 1997-01-10 Lepetit Spa Amides of antibiotic ge 2270 factors their preparation and pharmaceutical compositions containing them
US5416020A (en) 1992-09-29 1995-05-16 Bio-Technical Resources Lactobacillus delbrueckii ssp. bulgaricus strain and fermentation process for producing L-(+)-lactic acid
US6136577A (en) 1992-10-30 2000-10-24 Bioengineering Resources, Inc. Biological production of ethanol from waste gases with Clostridium ljungdahlii
US5807722A (en) 1992-10-30 1998-09-15 Bioengineering Resources, Inc. Biological production of acetic acid from waste gases with Clostridium ljungdahlii
FR2702492B1 (fr) 1993-03-12 1995-05-24 Rhone Poulenc Chimie Procédé de production par fermentation d'acide itaconique.
US5487987A (en) 1993-09-16 1996-01-30 Purdue Research Foundation Synthesis of adipic acid from biomass-derived carbon sources
US5521075A (en) 1994-12-19 1996-05-28 Michigan Biotechnology Institute Method for making succinic acid, anaerobiospirillum succiniciproducens variants for use in process and methods for obtaining variants
US5504004A (en) 1994-12-20 1996-04-02 Michigan Biotechnology Institute Process for making succinic acid, microorganisms for use in the process and methods of obtaining the microorganisms
US5700934A (en) 1995-03-01 1997-12-23 Dsm N.V. Process for the preparation of epsilon-caprolactam and epsilon-caprolactam precursors
US5478952A (en) 1995-03-03 1995-12-26 E. I. Du Pont De Nemours And Company Ru,Re/carbon catalyst for hydrogenation in aqueous solution
US5863782A (en) 1995-04-19 1999-01-26 Women's And Children's Hospital Synthetic mammalian sulphamidase and genetic sequences encoding same
US5686276A (en) 1995-05-12 1997-11-11 E. I. Du Pont De Nemours And Company Bioconversion of a fermentable carbon source to 1,3-propanediol by a single microorganism
FR2736927B1 (fr) 1995-07-18 1997-10-17 Rhone Poulenc Fibres & Polymer Enzymes a activite amidase, outils genetiques et microorganismes hotes permettant leur obtention et procede d'hydrolyse mettant en oeuvre lesdites enzymes
FR2736928B1 (fr) * 1995-07-18 1997-10-17 Rhone Poulenc Fibres & Polymer Enzymes ayant une activite amidase micro-organismes susceptibles de produire de telles enzymes et procede d'hydrolyse d'amides en faisant application
US5573931A (en) 1995-08-28 1996-11-12 Michigan Biotechnology Institute Method for making succinic acid, bacterial variants for use in the process, and methods for obtaining variants
US5869301A (en) 1995-11-02 1999-02-09 Lockhead Martin Energy Research Corporation Method for the production of dicarboxylic acids
US5770435A (en) 1995-11-02 1998-06-23 University Of Chicago Mutant E. coli strain with increased succinic acid production
EP0883683A1 (en) 1996-02-27 1998-12-16 Michigan State University Cloning and expression of the gene encoding thermoanaerobacter ethanolicus 39e secondary-alcohol dehydrogenase and enzyme biochemical characterization
US5958745A (en) 1996-03-13 1999-09-28 Monsanto Company Methods of optimizing substrate pools and biosynthesis of poly-β-hydroxybutyrate-co-poly-β-hydroxyvalerate in bacteria and plants
DE69638265D1 (de) 1996-07-01 2010-11-11 Emmaus Foundation Inc BIOLOGISCHE HESTELLUNG VON ESSIGSäURE AUS ABGASEN
KR100459818B1 (ko) 1996-09-02 2004-12-03 이. 아이. 두퐁 드 느무르 앤드 컴퍼니 ε-카프로락탐의 제조방법
US6117658A (en) 1997-02-13 2000-09-12 James Madison University Methods of making polyhydroxyalkanoates comprising 4-hydroxybutyrate monomer units
KR100516986B1 (ko) 1997-02-19 2005-09-26 코닌클리즈케 디에스엠 엔.브이. 6-아미노카프론산 유도체를 과열 수증기와 접촉시킴으로써 촉매 없이 카프로락탐을 제조하는 방법
US6274790B1 (en) 1997-04-14 2001-08-14 The University Of British Columbia Nucleic acids encoding a plant enzyme involved in very long chain fatty acid synthesis
KR19990013007A (ko) 1997-07-31 1999-02-25 박원훈 형질전환된 대장균 ss373(kctc 8818p)과 이를 이용한숙신산의 생산방법
JPH11103863A (ja) 1997-10-08 1999-04-20 Nippon Shokubai Co Ltd マレイン酸異性化酵素遺伝子
US6280986B1 (en) * 1997-12-01 2001-08-28 The United States Of America As Represented By The Secretary Of Agriculture Stabilization of pet operon plasmids and ethanol production in bacterial strains lacking lactate dehydrogenase and pyruvate formate lyase activities
EP0943608A1 (en) * 1998-03-20 1999-09-22 Dsm N.V. Process for the continuous purification of crude epsilon--caprolactam
CA2325598A1 (en) 1998-04-13 1999-10-21 The University Of Georgia Research Foundation, Inc. Pyruvate carboxylase overexpression for enhanced production of oxaloacetate-derived biochemicals in microbial cells
US20030087381A1 (en) 1998-04-13 2003-05-08 University Of Georgia Research Foundation, Inc. Metabolically engineered organisms for enhanced production of oxaloacetate-derived biochemicals
US6159738A (en) 1998-04-28 2000-12-12 University Of Chicago Method for construction of bacterial strains with increased succinic acid production
DE19820652A1 (de) 1998-05-08 1999-11-11 Basf Ag Kationische Rutheniumkomplexe, Verfahren zu ihrer Herstellung und ihre Verwendung
US6432686B1 (en) 1998-05-12 2002-08-13 E. I. Du Pont De Nemours And Company Method for the production of 1,3-propanediol by recombinant organisms comprising genes for vitamin B12 transport
US6444784B1 (en) 1998-05-29 2002-09-03 Exxonmobil Research & Engineering Company Wax crystal modifiers (LAW657)
AU5101599A (en) 1998-07-15 2000-02-07 E.I. Du Pont De Nemours And Company Tetrahydrofolate metabolism enzymes
DE19856136C2 (de) 1998-12-04 2002-10-24 Pasteur Institut Verfahren und Vorrichtung zur Selektion beschleunigter Proliferation lebender Zellen in Suspension
AU3482200A (en) 1999-02-02 2000-08-25 Bernhard Palsson Methods for identifying drug targets based on genomic sequence data
US6686310B1 (en) 1999-02-09 2004-02-03 E. I. Du Pont De Nemours And Company High surface area sol-gel route prepared hydrogenation catalysts
US6365376B1 (en) 1999-02-19 2002-04-02 E. I. Du Pont De Nemours And Company Genes and enzymes for the production of adipic acid intermediates
US6498242B1 (en) * 1999-02-19 2002-12-24 E. I. Du Pont De Nemours And Company Biological method for the production of adipic acid and intermediates
US6448473B1 (en) 1999-03-05 2002-09-10 Monsanto Technology Llc Multigene expression vectors for the biosynthesis of products via multienzyme biological pathways
BR0010806B1 (pt) 1999-05-21 2014-02-18 Métodos e materiais para a síntese de produtos orgânicos
US6852517B1 (en) 1999-08-30 2005-02-08 Wisconsin Alumni Research Foundation Production of 3-hydroxypropionic acid in recombinant organisms
CZ20021013A3 (en) * 1999-09-21 2002-12-11 Omnigene Bioproducts Methods and microorganisms for production of panto-compounds
US6660857B2 (en) 2000-02-03 2003-12-09 Dsm N.V. Process for the preparation of ε-caprolactam
WO2001080601A1 (fr) * 2000-04-14 2001-10-25 Ibiden Co., Ltd. Dispositif de chauffage en ceramique
ES2281412T3 (es) * 2000-04-21 2007-10-01 Mitsubishi Rayon Co., Ltd. Composicion de resina epoxi y prepreg fabricado con la composicion de resina epoxi.
US6878861B2 (en) 2000-07-21 2005-04-12 Washington State University Research Foundation Acyl coenzyme A thioesterases
KR100879577B1 (ko) 2000-07-25 2009-01-22 엠마우스 파운데이션 인코퍼레이티드 미생물 발효로부터 에탄올의 생산을 증가시키기 위한 방법
US7698463B2 (en) 2000-09-12 2010-04-13 Sri International System and method for disseminating topology and link-state information to routing nodes in a mobile ad hoc network
US7233567B1 (en) * 2000-09-22 2007-06-19 Nortel Networks Limited Apparatus and method for supporting multiple traffic redundancy mechanisms
AR031480A1 (es) 2000-11-20 2003-09-24 Cargill Inc Acido 3-hidroxipropionico y otros compuestos organicos
JP2004521619A (ja) 2000-11-22 2004-07-22 カージル ダウ ポリマーズ エルエルシー 有機生成物の合成のための方法及び材料
CN1358841A (zh) 2000-12-11 2002-07-17 云南省微生物研究所 云南链霉菌
CN1491282A (zh) 2000-12-28 2004-04-21 丰田自动车株式会社 异戊二烯醇的制备方法
AU2002239855B2 (en) 2001-01-10 2006-11-23 The Penn State Research Foundation Method and system for modeling cellular metabolism
US7127379B2 (en) 2001-01-31 2006-10-24 The Regents Of The University Of California Method for the evolutionary design of biochemical reaction networks
US20030059792A1 (en) 2001-03-01 2003-03-27 Palsson Bernhard O. Models and methods for determining systemic properties of regulated reaction networks
US6743610B2 (en) 2001-03-30 2004-06-01 The University Of Chicago Method to produce succinic acid from raw hydrolysates
JP4630486B2 (ja) 2001-05-28 2011-02-09 ダイセル化学工業株式会社 新規な(r)−2,3−ブタンジオール脱水素酵素、その製造方法、及びこれを利用した光学活性アルコールの製造方法
CA2356540A1 (en) 2001-08-30 2003-02-28 Emory University Expressed dna sequences involved in mitochondrial functions
MXPA04004194A (es) 2001-11-02 2005-03-31 Rice University Sistema de recirculacion para la manipulacion de disponibilidad de nadh intracelular.
US7309597B2 (en) 2002-01-18 2007-12-18 Cargill, Incorporated Alanine 2,3-Aminomutase
WO2003066863A1 (fr) 2002-02-06 2003-08-14 Showa Denko K.K. Gene reductase d'un compose carbonyle alpha-substitue-alpha, beta-insature
US20030224363A1 (en) 2002-03-19 2003-12-04 Park Sung M. Compositions and methods for modeling bacillus subtilis metabolism
AU2003222128A1 (en) 2002-03-29 2003-10-13 Genomatica, Inc. Human metabolic models and methods
AU2003234790A1 (en) 2002-05-10 2003-11-11 Kyowa Hakko Kogyo Co., Ltd. Process for producing mevalonic acid
US7856317B2 (en) 2002-06-14 2010-12-21 Genomatica, Inc. Systems and methods for constructing genomic-based phenotypic models
CA2491753A1 (en) 2002-07-10 2004-03-04 The Penn State Research Foundation Method for determining gene knockout strategies
US7826975B2 (en) 2002-07-10 2010-11-02 The Penn State Research Foundation Method for redesign of microbial production systems
WO2004007688A2 (en) 2002-07-15 2004-01-22 Kosan Biosciences, Inc. Metabolic pathways for starter units in polyketide biosynthesis
CA2501574C (en) 2002-10-04 2013-12-03 E. I. Du Pont De Nemours And Company Process for the biological production of 1,3-propanediol with high yield
CA2500761C (en) 2002-10-15 2012-11-20 Bernhard O. Palsson Methods and systems to identify operational reaction pathways
AU2003287625A1 (en) 2002-11-06 2004-06-03 University Of Florida Materials and methods for the efficient production of acetate and other products
CN1266858C (zh) * 2002-11-18 2006-07-26 华为技术有限公司 一种业务回退的实现方法
US7960599B2 (en) 2003-01-13 2011-06-14 Elevance Renewable Sciences, Inc. Method for making industrial chemicals
US7432091B2 (en) 2003-02-24 2008-10-07 Research Institute Of Innovative Technology For The Earth Highly efficient hydrogen production method using microorganism
RU2268300C2 (ru) 2003-04-07 2006-01-20 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИЙ, ОБЛАДАЮЩИХ ПОВЫШЕННОЙ ЭКСПРЕССИЕЙ ГЕНА pckA
WO2005010182A1 (ja) 2003-07-29 2005-02-03 Research Institute Of Innovative Technology For The Earth コリネ型細菌形質転換体及びそれを用いるジカルボン酸の製造方法
US7927859B2 (en) 2003-08-22 2011-04-19 Rice University High molar succinate yield bacteria by increasing the intracellular NADH availability
WO2005026349A1 (ja) 2003-09-17 2005-03-24 Mitsubishi Chemical Corporation 非アミノ有機酸の製造方法
US7244610B2 (en) 2003-11-14 2007-07-17 Rice University Aerobic succinate production in bacteria
KR20060125804A (ko) * 2003-12-18 2006-12-06 바스프 악티엔게젤샤프트 코리네박테륨 글루타미쿰의 발효에 의한 리신의 제조 방법
FR2864967B1 (fr) 2004-01-12 2006-05-19 Metabolic Explorer Sa Microorganisme evolue pour la production de 1,2-propanediol
EP1706501B1 (en) * 2004-01-19 2010-01-13 DSM IP Assets B.V. Biochemical synthesis of 6-amino caproic acid
US7608700B2 (en) 2004-03-08 2009-10-27 North Carolina State University Lactobacillus acidophilus nucleic acid sequences encoding stress-related proteins and uses therefor
US7002679B2 (en) * 2004-05-11 2006-02-21 Duke University Encoded excitation source Raman spectroscopy methods and systems
ATE537269T1 (de) * 2004-05-21 2011-12-15 Univ California Verfahren zur verbesserung der herstellung von isoprenoid-zusammensetzungen
JP2008502728A (ja) 2004-06-10 2008-01-31 ボード、オブ、トラスティーズ、オブ、ミシガン、ステイト、ユニバーシティ リジンからのカプロラクタムの合成
DE102004031177A1 (de) 2004-06-29 2006-01-19 Henkel Kgaa Neue Geruchsstoffe bildende Genprodukte von Bacillus licheniformis und darauf aufbauende verbesserte biotechnologische Produktionsverfahren
WO2006020663A2 (en) 2004-08-09 2006-02-23 Rice University Aerobic succinate production in bacteria
US7223567B2 (en) 2004-08-27 2007-05-29 Rice University Mutant E. coli strain with increased succinic acid production
JP4712716B2 (ja) 2004-09-09 2011-06-29 財団法人地球環境産業技術研究機構 プロモーター機能を有するdna断片
KR20070065870A (ko) 2004-09-17 2007-06-25 라이스 유니버시티 다량의 숙신산염을 생산하는 세균
US7283014B2 (en) * 2004-10-25 2007-10-16 Johnson Ray M High power absorbing waveguide termination for a microwave transmission line
US20060096946A1 (en) * 2004-11-10 2006-05-11 General Electric Company Encapsulated wafer processing device and process for making thereof
WO2006069174A2 (en) 2004-12-22 2006-06-29 Rice University Simultaneous anaerobic production of isoamyl acetate and succinic acid
JP2006204255A (ja) 2005-01-31 2006-08-10 Canon Inc アセチル−CoAアシルトランスフェラーゼ遺伝子破壊ポリヒドロキシアルカノエート生産菌、またこれを利用したポリヒドロキシアルカノエート生産方法
US20090068207A1 (en) 2005-04-15 2009-03-12 Vascular Biogenics Ltd. Compositions Containing Beta 2-Glycoprotein I-Derived Peptides for the Prevention and/or Treatment of Vascular Disease
KR100679638B1 (ko) 2005-08-19 2007-02-06 한국과학기술원 포메이트 디하이드로게나제 d 또는 e를 코딩하는 유전자로 형질전환된 미생물 및 이를 이용한 숙신산의 제조방법
KR100676160B1 (ko) 2005-08-19 2007-02-01 한국과학기술원 말릭효소를 코딩하는 유전자로 형질전환된 재조합 미생물 및 이를 이용한 숙신산의 제조방법
AU2006287257A1 (en) 2005-09-09 2007-03-15 Genomatica, Inc. Methods and organisms for the growth-coupled production of succinate
US9297028B2 (en) 2005-09-29 2016-03-29 Butamax Advanced Biofuels Llc Fermentive production of four carbon alcohols
US20080274526A1 (en) 2007-05-02 2008-11-06 Bramucci Michael G Method for the production of isobutanol
RU2394913C2 (ru) 2005-10-26 2010-07-20 Е.И.Дюпон Де Немур Энд Компани Ферментативное получение четырехуглеродных спиртов
JPWO2007066430A1 (ja) 2005-12-08 2009-05-14 協和発酵キリン株式会社 ペプチドの製造法
US7801128B2 (en) 2006-03-31 2010-09-21 Amazon Technologies, Inc. Managing communications between computing nodes
US8962298B2 (en) 2006-05-02 2015-02-24 Butamax Advanced Biofuels Llc Recombinant host cell comprising a diol dehydratase
US20070271453A1 (en) 2006-05-19 2007-11-22 Nikia Corporation Identity based flow control of IP traffic
US8017364B2 (en) 2006-12-12 2011-09-13 Butamax(Tm) Advanced Biofuels Llc Solvent tolerant microorganisms
EP2121949B1 (en) 2006-12-21 2013-05-08 GEVO, Inc. Butanol production by metabolically engineered yeast
CA2675026A1 (en) 2007-01-12 2008-07-24 The Regents Of The University Of Colorado, A Body Corporate Compositions and methods for enhancing tolerance for the production of organic chemicals produced by microorganisms
JP5551448B2 (ja) 2007-03-16 2014-07-16 ジェノマティカ・インコーポレイテッド 1,4−ブタンジオールおよびその前駆体の生合成のための組成物および方法
EP2147111A4 (en) 2007-04-18 2010-06-23 Gevo Inc MANIPULATED MICROORGANISMS FOR THE MANUFACTURE OF ISOPROPANOL
NZ579780A (en) 2007-04-18 2012-07-27 Butamax Advanced Biofuels Llc Fermentive production of isobutanol using highly active ketol-acid reductoisomerase enzymes
US20080274522A1 (en) 2007-05-02 2008-11-06 Bramucci Michael G Method for the production of 2-butanone
AU2008254423C1 (en) 2007-05-17 2016-06-02 Eastman Renewable Materials, Llc Methods and compositions for producing solvents
EP2017344A1 (en) 2007-07-20 2009-01-21 Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO Production of itaconic acid
CN101970673A (zh) 2007-07-23 2011-02-09 帝斯曼知识产权资产管理有限公司 真核细胞中的丁醇生产
US8285554B2 (en) * 2007-07-27 2012-10-09 Dsp Group Limited Method and system for dynamic aliasing suppression
US7947483B2 (en) 2007-08-10 2011-05-24 Genomatica, Inc. Methods and organisms for the growth-coupled production of 1,4-butanediol
US20100221800A1 (en) 2007-10-12 2010-09-02 The Regents Of The University Of California Microorganism engineered to produce isopropanol
WO2009085278A1 (en) 2007-12-21 2009-07-09 Ls9, Inc. Methods and compositions for producing olefins
WO2009094485A1 (en) 2008-01-22 2009-07-30 Genomatica, Inc. Methods and organisms for utilizing synthesis gas or other gaseous carbon sources and methanol
US20090246842A1 (en) 2008-02-15 2009-10-01 Gevo, Inc. Engineered microorganisms for producing propanol
US7981647B2 (en) 2008-03-03 2011-07-19 Joule Unlimited, Inc. Engineered CO2 fixing microorganisms producing carbon-based products of interest
CN104178532B (zh) * 2008-03-11 2018-09-25 基因组股份公司 从5-甲酰缬草酸制备6-氨基己酸
NO2252698T3 (pl) * 2008-03-11 2018-04-21
CN102066551B (zh) 2008-03-27 2013-10-09 基因组股份公司 用于产生己二酸和其他化合物的微生物
BRPI0913901A2 (pt) 2008-06-17 2016-12-13 Genomatica Inc micro-organismos e métodos para a biossíntese de fumarato, malato e acrilato
WO2010022763A1 (en) 2008-08-25 2010-03-04 Metabolic Explorer Method for the preparation of 2-hydroxy-isobutyrate
US8344188B2 (en) 2008-10-16 2013-01-01 Maverick Biofuels, Inc. Methods and apparatus for synthesis of alcohols from syngas
MY183971A (en) 2008-12-12 2021-03-17 Metabolix Inc Green process and compositions for producing poly(5hv) and 5 carbon chemicals
WO2010071697A1 (en) 2008-12-16 2010-06-24 Genomatica, Inc. Microorganisms and methods for conversion of syngas and other carbon sources to useful products
JP2012520070A (ja) * 2009-03-11 2012-09-06 ディーエスエム アイピー アセッツ ビー.ブイ. アジピン酸の調製
BRPI1011227A8 (pt) 2009-05-07 2019-02-26 Genomatica Inc microorganismos e métodos para a biossíntese de adipato, hexametilenodiamina e ácido 6-aminocapróico.
EP4056706A1 (en) 2009-06-04 2022-09-14 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol and related methods
EP2510102A4 (en) 2009-12-10 2014-01-22 Genomatica Inc METHODS AND ORGANIZATIONS FOR THE CONVERSION OF SYNTHESIS GAS OR OTHER CARBONACEOUS GAS SOURCES AND METHANOL TO 1,3-BUTANEDIOL

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