PL187545B1 - Izolowana cząsteczka DNA zawierająca region kodujący zmodyfikowaną oksydazę protoporfirynogenu (protox), sposób wytwarzania roślin, które są tolerancyjne lub oporne na herbicyd hamujący oksydazę protoporfirynogenu oraz sposób kontrolowania wzrostu niepożądanej wegetacji - Google Patents
Izolowana cząsteczka DNA zawierająca region kodujący zmodyfikowaną oksydazę protoporfirynogenu (protox), sposób wytwarzania roślin, które są tolerancyjne lub oporne na herbicyd hamujący oksydazę protoporfirynogenu oraz sposób kontrolowania wzrostu niepożądanej wegetacjiInfo
- Publication number
- PL187545B1 PL187545B1 PL97359654A PL35965497A PL187545B1 PL 187545 B1 PL187545 B1 PL 187545B1 PL 97359654 A PL97359654 A PL 97359654A PL 35965497 A PL35965497 A PL 35965497A PL 187545 B1 PL187545 B1 PL 187545B1
- Authority
- PL
- Poland
- Prior art keywords
- protox
- amino acid
- seq
- plant
- gene
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/001—Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
- C12N15/8214—Plastid transformation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8274—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for herbicide resistance
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Medicinal Chemistry (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1270596P | 1996-02-28 | 1996-02-28 | |
| US1361296P | 1996-02-28 | 1996-02-28 | |
| US2000396P | 1996-06-21 | 1996-06-21 | |
| PCT/US1997/003313 WO1997032011A1 (en) | 1996-02-28 | 1997-02-27 | Dna molecules encoding plant protoporphyrinogen oxidase and inhibitor-resistant mutants thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL187545B1 true PL187545B1 (pl) | 2004-07-30 |
Family
ID=27359690
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL97359654A PL187545B1 (pl) | 1996-02-28 | 1997-02-27 | Izolowana cząsteczka DNA zawierająca region kodujący zmodyfikowaną oksydazę protoporfirynogenu (protox), sposób wytwarzania roślin, które są tolerancyjne lub oporne na herbicyd hamujący oksydazę protoporfirynogenu oraz sposób kontrolowania wzrostu niepożądanej wegetacji |
| PL97328617A PL328617A1 (en) | 1996-02-28 | 1997-02-27 | Promotors of protoporphyrinogen oxidase genes residing in plants |
| PL97328651A PL187094B1 (pl) | 1996-02-28 | 1997-02-27 | Izolowana cząsteczka DNA kodująca enzym oksydazę protoporfirynogenu (protox) pszenicy, chimerowy gen, sposób wytwarzania roślin oraz sposób zwalczania chwastów |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL97328617A PL328617A1 (en) | 1996-02-28 | 1997-02-27 | Promotors of protoporphyrinogen oxidase genes residing in plants |
| PL97328651A PL187094B1 (pl) | 1996-02-28 | 1997-02-27 | Izolowana cząsteczka DNA kodująca enzym oksydazę protoporfirynogenu (protox) pszenicy, chimerowy gen, sposób wytwarzania roślin oraz sposób zwalczania chwastów |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US6018105A (enExample) |
| EP (2) | EP0885305A1 (enExample) |
| JP (2) | JP2000506011A (enExample) |
| KR (2) | KR19990087356A (enExample) |
| CN (2) | CN1175107C (enExample) |
| AU (2) | AU724893B2 (enExample) |
| BR (2) | BR9707783A (enExample) |
| CA (2) | CA2247074C (enExample) |
| CZ (2) | CZ297325B6 (enExample) |
| HU (2) | HUP9900623A3 (enExample) |
| PL (3) | PL187545B1 (enExample) |
| UA (1) | UA70912C2 (enExample) |
| WO (2) | WO1997032028A1 (enExample) |
Families Citing this family (62)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5767373A (en) | 1994-06-16 | 1998-06-16 | Novartis Finance Corporation | Manipulation of protoporphyrinogen oxidase enzyme activity in eukaryotic organisms |
| US6084155A (en) | 1995-06-06 | 2000-07-04 | Novartis Ag | Herbicide-tolerant protoporphyrinogen oxidase ("protox") genes |
| WO1997004088A1 (en) * | 1995-07-20 | 1997-02-06 | Sumitomo Chemical Company, Ltd. | Porphyrin-accumulating type herbicide resistance gene |
| EP1007703A1 (en) * | 1996-12-27 | 2000-06-14 | Sumitomo Chemical Company, Limited | Methods of conferring ppo-inhibiting herbicide resistance to plants by gene manipulation |
| ZA98371B (en) * | 1997-01-31 | 1999-07-16 | Du Pont | Genetically transformed plants demonstrating resistance to porphyrinogen biosynthesis-inhibiting herbicides. |
| US6905852B1 (en) * | 1997-09-11 | 2005-06-14 | Nihon Nohyaku Co., Ltd. | Herbicide-resistant protoporphyrinogen oxidase isolated from Nicotiana tabacum |
| US6362398B1 (en) | 1998-03-11 | 2002-03-26 | Syngenta Participations Ag | ClpP plastid promoter sequence |
| HUP0101089A3 (en) * | 1998-03-11 | 2002-12-28 | Novartis Ag | Novel plant plastid promoter sequence |
| AU769868B2 (en) | 1998-04-10 | 2004-02-05 | Sumitomo Chemical Company, Limited | A method for evaluating the ability of a compound to inhibit the protoporphyrinogen oxidase activity |
| US6906245B1 (en) | 1998-04-30 | 2005-06-14 | Sumitomo Chemical Company, Limited | Method for producing transgenic plants resistant to weed control compounds which disrupt the porphyrin pathways of plants |
| JP4788011B2 (ja) * | 1998-04-30 | 2011-10-05 | 住友化学株式会社 | 雑草防除剤耐性の付与方法 |
| AU753020B2 (en) * | 1998-04-30 | 2002-10-03 | Sumitomo Chemical Company, Limited | Method for giving resistance to weed control compounds to plants |
| AR020078A1 (es) | 1998-05-26 | 2002-04-10 | Syngenta Participations Ag | Metodo para alterar la expresion de un gen objetivo en una celula de planta |
| US6492578B1 (en) * | 1998-07-10 | 2002-12-10 | Calgene Llc | Expression of herbicide tolerance genes in plant plastids |
| WO2000003022A2 (en) * | 1998-07-10 | 2000-01-20 | Calgene Llc | Expression of herbicide tolerance genes in plant plastids |
| RU2240001C2 (ru) * | 1998-11-10 | 2004-11-20 | Зингента Партисипейшнс Аг | Гербицидная композиция и способ борьбы с нежелательной растительностью в посевах культурных растений с использованием этой композиции |
| AR021121A1 (es) * | 1998-11-10 | 2002-06-12 | Syngenta Participations Ag | Composicion herbicida |
| GB9828201D0 (en) * | 1998-12-21 | 1999-02-17 | Zenco No 4 Ltd | Genetic modification of compositae |
| WO2001007590A2 (en) * | 1999-07-27 | 2001-02-01 | Syngenta Participations Ag | Chimeric genes for plastid expression |
| AU5536000A (en) * | 1999-08-13 | 2001-03-13 | Syngenta Participations Ag | Herbicide-tolerant protoporphyrinogen oxidase |
| US6617498B1 (en) * | 1999-09-03 | 2003-09-09 | Pioneer-Hi-Bred International, Inc. | Inducible promoters |
| BR0014681A (pt) * | 1999-10-11 | 2002-08-20 | Processo para aumentar o rendimento ou a biomassa da colheita usando o gene para protoporfirinógeno oxidase | |
| JP4821036B2 (ja) * | 1999-10-29 | 2011-11-24 | 住友化学株式会社 | 除草剤耐性植物 |
| WO2001036606A2 (de) * | 1999-11-16 | 2001-05-25 | Basf Plant Science Gmbh | Protoporphyrinogen-ix-oxidase und seine verwendung |
| CN104531702A (zh) | 1999-12-16 | 2015-04-22 | 孟山都技术有限公司 | 新型植物表达构建物 |
| AU2001260114A1 (en) * | 2000-03-14 | 2001-09-24 | Syngenta Participations Ag | Protoporphyrinogen oxidase ("protox") genes |
| US6713259B2 (en) * | 2000-09-13 | 2004-03-30 | Monsanto Technology Llc | Corn event MON810 and compositions and methods for detection thereof |
| AR037413A1 (es) * | 2001-11-27 | 2004-11-10 | Valent Biosciences Corp | Composicion herbicida intensificada |
| EP1576178A4 (en) | 2002-12-26 | 2008-03-05 | Syngenta Participations Ag | COMPOUNDS WITH CELL PROPERATION AND POLYPEPTIDE USES DAF R |
| WO2005037993A2 (en) | 2003-10-06 | 2005-04-28 | Syngenta Participations Ag | Promoters functional in plant plastids |
| BRPI0508518A (pt) | 2004-03-08 | 2007-08-14 | Syngenta Participations Ag | proteìna e promotor de semente de milho rica em glutamina |
| JP4720223B2 (ja) * | 2004-05-18 | 2011-07-13 | 住友化学株式会社 | 除草活性化合物耐性植物 |
| CA2584934A1 (en) | 2007-04-17 | 2008-10-17 | University Of Guelph | Nitrogen-regulated sugar sensing gene and protein and modulation thereof |
| EP2573183B1 (en) | 2009-01-22 | 2017-01-04 | Syngenta Participations AG | Mutant hydroxyphenylpyruvate dioxgenase polypeptids and methods of use |
| AU2010210645A1 (en) | 2009-02-06 | 2011-07-07 | Syngenta Participations Ag | Modification of multidomain enzyme for expression in plants |
| EP2451946B2 (en) | 2009-07-10 | 2018-08-29 | Syngenta Participations AG | Novel hydroxyphenylpyruvate dioxygenase polypeptides and methods of use |
| UA112969C2 (uk) * | 2010-08-03 | 2016-11-25 | Сібас Юс Ллс | Рослина, стійка до одного або більше ррх-інгібуючих гербіцидів, яка містить мутантний ген протопорфіриноген ix оксидази (ррх) |
| JP2012056817A (ja) * | 2010-09-10 | 2012-03-22 | Kochi Univ Of Technology | 単細胞藻類の細胞破砕液を利用したアミノ酸含有有機液肥 |
| EP2652139B1 (en) * | 2010-12-16 | 2021-10-20 | BASF Agro B.V. | Plants having increased tolerance to herbicides |
| AR091489A1 (es) | 2012-06-19 | 2015-02-11 | Basf Se | Plantas que tienen una mayor tolerancia a herbicidas inhibidores de la protoporfirinogeno oxidasa (ppo) |
| US10041087B2 (en) | 2012-06-19 | 2018-08-07 | BASF Agro B.V. | Plants having increased tolerance to herbicides |
| CN104107437B (zh) * | 2013-06-09 | 2015-08-26 | 厦门成坤生物技术有限公司 | 一种用于治疗乙型病毒性肝炎的rna干扰组合物及其制备方法 |
| BR112016002837B1 (pt) * | 2013-08-12 | 2022-06-21 | BASF Agro B.V. | Método para controlar vegetação indesejada, método para produzir uma célula vegetal transgênica, método para produzir uma planta transgênica e cassete de expressão |
| AU2014307664A1 (en) * | 2013-08-12 | 2016-02-18 | BASF Agro B.V. | Plants having increased tolerance to herbicides (PPO) |
| EP3310154A4 (en) * | 2015-06-17 | 2019-02-13 | BASF Agro B.V. | PLANTS WITH INCREASED TOLERANCE AGAINST HERBICIDES |
| CN111423990B (zh) * | 2020-04-10 | 2021-08-27 | 科稷达隆(北京)生物技术有限公司 | 一种乙氧氟草醚敏感型酵母菌及其制备方法 |
| US20240124432A1 (en) | 2020-11-24 | 2024-04-18 | Syngenta Crop Protection Ag | Herbicidal compounds |
| CN115247157A (zh) * | 2021-04-02 | 2022-10-28 | 青岛清原化合物有限公司 | 对ppo抑制剂类除草剂具有耐受性的ppo多肽及应用 |
| CN118956784A (zh) * | 2021-04-02 | 2024-11-15 | 青岛清原种子科学有限公司 | 对ppo抑制剂类除草剂具有耐受性的ppo多肽及应用 |
| JP2024514827A (ja) | 2021-04-07 | 2024-04-03 | シンジェンタ クロップ プロテクション アクチェンゲゼルシャフト | 除草化合物 |
| CN115340987B (zh) * | 2021-05-12 | 2023-12-01 | 北京大北农生物技术有限公司 | 除草剂耐受性蛋白质、其编码基因及用途 |
| WO2023169984A1 (en) | 2022-03-11 | 2023-09-14 | Syngenta Crop Protection Ag | Herbicidal compounds |
| US20250230462A1 (en) * | 2022-03-29 | 2025-07-17 | Qingdao Kingagroot Chemical Compound Co., Ltd. | Ppo2 polypeptide having tolerance to ppo inhibitor herbicide and application |
| IL292199B2 (en) * | 2022-04-12 | 2024-02-01 | Plantarc Bio Ltd | A method for optimizing gene expression levels in plants |
| WO2023222589A1 (en) | 2022-05-20 | 2023-11-23 | Syngenta Crop Protection Ag | Herbicidal compounds |
| AR129821A1 (es) | 2022-07-13 | 2024-10-02 | Syngenta Crop Protection Ag | Compuestos herbicidas |
| AU2024225839A1 (en) | 2023-02-24 | 2025-08-07 | Syngenta Crop Protection Ag | Herbicidal compositions |
| CN120676860A (zh) | 2023-02-24 | 2025-09-19 | 先正达农作物保护股份公司 | 除草组合物 |
| WO2024194063A1 (en) | 2023-03-17 | 2024-09-26 | Syngenta Crop Protection Ag | Herbicidal triazine derivatives |
| AU2024292019A1 (en) | 2023-07-20 | 2026-01-15 | Syngenta Crop Protection Ag | Herbicidal compositions |
| WO2025016884A1 (en) | 2023-07-20 | 2025-01-23 | Syngenta Crop Protection Ag | Herbicidal compositions |
| CN120230766B (zh) * | 2025-05-29 | 2025-08-26 | 隆平生物技术(海南)有限公司 | 耐除草剂基因ppo的变体及其编码蛋白和应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0360750A3 (en) * | 1988-09-22 | 1991-01-02 | Ciba-Geigy Ag | Novel herbicide tolerant plants |
| CN1039283C (zh) * | 1988-12-12 | 1998-07-29 | Fmc公司 | 卟啉的应用 |
| NZ231658A (en) * | 1988-12-12 | 1992-05-26 | Fmc Corp | Inhibitors of protoporphyrinogen oxidase and compositions for killing tumour cells |
| US5086169A (en) * | 1989-04-20 | 1992-02-04 | The Research Foundation Of State University Of New York | Isolated pollen-specific promoter of corn |
| US5451513A (en) * | 1990-05-01 | 1995-09-19 | The State University of New Jersey Rutgers | Method for stably transforming plastids of multicellular plants |
| ATE195554T1 (de) * | 1990-05-18 | 2000-09-15 | Mycogen Plant Science Inc | Rekombinanter promoter zur genexpression in monokotylen |
| IL98405A0 (en) * | 1990-06-11 | 1992-07-15 | Fmc Corp | Pharmaceutical compositions containing enzyme inhibiting agents |
| US5290926A (en) * | 1990-09-14 | 1994-03-01 | Ciba-Geigy Corporation | Isolated DNA Encoding plant histidinol dehydrogenase |
| ATE171212T1 (de) * | 1994-06-14 | 1998-10-15 | Neurocrine Biosciences Inc | Corticotropin freisetzende rezeptoren des faktor 2 |
| US5767373A (en) * | 1994-06-16 | 1998-06-16 | Novartis Finance Corporation | Manipulation of protoporphyrinogen oxidase enzyme activity in eukaryotic organisms |
| WO1997004088A1 (en) * | 1995-07-20 | 1997-02-06 | Sumitomo Chemical Company, Ltd. | Porphyrin-accumulating type herbicide resistance gene |
| AU703838B2 (en) * | 1995-08-10 | 1999-04-01 | Rutgers University | Nuclear-encoded transcription system in plastids of higher plants |
-
1997
- 1997-02-27 CA CA002247074A patent/CA2247074C/en not_active Expired - Fee Related
- 1997-02-27 CN CNB971927014A patent/CN1175107C/zh not_active Expired - Fee Related
- 1997-02-27 BR BR9707783A patent/BR9707783A/pt not_active IP Right Cessation
- 1997-02-27 HU HU9900623A patent/HUP9900623A3/hu unknown
- 1997-02-27 JP JP9531213A patent/JP2000506011A/ja not_active Ceased
- 1997-02-27 PL PL97359654A patent/PL187545B1/pl not_active IP Right Cessation
- 1997-02-27 EP EP97908846A patent/EP0885305A1/en not_active Withdrawn
- 1997-02-27 WO PCT/US1997/003343 patent/WO1997032028A1/en not_active Ceased
- 1997-02-27 PL PL97328617A patent/PL328617A1/xx unknown
- 1997-02-27 CZ CZ0272698A patent/CZ297325B6/cs not_active IP Right Cessation
- 1997-02-27 KR KR1019980706766A patent/KR19990087356A/ko not_active Ceased
- 1997-02-27 EP EP97907988A patent/EP0883682A1/en not_active Withdrawn
- 1997-02-27 CN CN97192702A patent/CN1212725A/zh active Pending
- 1997-02-27 UA UA98084642A patent/UA70912C2/uk unknown
- 1997-02-27 KR KR1019980706878A patent/KR100493500B1/ko not_active Expired - Fee Related
- 1997-02-27 PL PL97328651A patent/PL187094B1/pl not_active IP Right Cessation
- 1997-02-27 CA CA002247797A patent/CA2247797A1/en not_active Abandoned
- 1997-02-27 JP JP53120397A patent/JP3961570B2/ja not_active Expired - Fee Related
- 1997-02-27 BR BR9707769A patent/BR9707769A/pt not_active Application Discontinuation
- 1997-02-27 AU AU19846/97A patent/AU724893B2/en not_active Ceased
- 1997-02-27 CZ CZ982727A patent/CZ272798A3/cs unknown
- 1997-02-27 WO PCT/US1997/003313 patent/WO1997032011A1/en not_active Ceased
- 1997-02-27 AU AU20654/97A patent/AU724838B2/en not_active Ceased
- 1997-02-27 HU HU9901044A patent/HUP9901044A3/hu not_active Application Discontinuation
- 1997-02-28 US US08/808,323 patent/US6018105A/en not_active Expired - Fee Related
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