PL185515B1 - Nowa pochodna imidazolu, kompozycja farmaceutyczna, zastosowanie nowej pochodnej imidazolu, sposób wytwarzania nowej pochodnej imidazolu i nowa pochodna 2-aminopirymidyny - Google Patents

Info

Publication number

PL185515B1

PL185515B1 PL96323916A PL32391696A PL185515B1 PL 185515 B1 PL185515 B1 PL 185515B1 PL 96323916 A PL96323916 A PL 96323916A PL 32391696 A PL32391696 A PL 32391696A PL 185515 B1 PL185515 B1 PL 185515B1

Authority

PL

Poland

Prior art keywords

formula

alkyl

group

imidazole

fluorophenyl

Prior art date

1995-06-07

Links

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• 150000002460 imidazoles Chemical class 0.000 claims abstract description 12
• 238000000034 method Methods 0.000 claims description 130
• RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Natural products C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 claims description 113
• -1 benzyloxy, methylenedioxy Chemical group 0.000 claims description 87
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• 238000002360 preparation method Methods 0.000 claims description 40
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• 125000004527 pyrimidin-4-yl group Chemical group N1=CN=C(C=C1)* 0.000 claims description 36
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• 238000004519 manufacturing process Methods 0.000 claims description 33
• 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 32
• 238000011282 treatment Methods 0.000 claims description 32
• WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 claims description 30
• 150000003839 salts Chemical class 0.000 claims description 29
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• 125000001255 4-fluorophenyl group Chemical group [H]C1=C([H])C(*)=C([H])C([H])=C1F 0.000 claims description 23
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