ATE336484T1 - Pyrimidine verbindungen - Google Patents

Pyrimidine verbindungen

Info

Publication number
ATE336484T1
ATE336484T1 AT99940404T AT99940404T ATE336484T1 AT E336484 T1 ATE336484 T1 AT E336484T1 AT 99940404 T AT99940404 T AT 99940404T AT 99940404 T AT99940404 T AT 99940404T AT E336484 T1 ATE336484 T1 AT E336484T1
Authority
AT
Austria
Prior art keywords
pdat
hil
alkyl
formula
substituent
Prior art date
Application number
AT99940404T
Other languages
English (en)
Inventor
Gloria Anne Breault
Philip John Jewsbury
Janet Elizabeth Pease
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9818987.1A external-priority patent/GB9818987D0/en
Priority claimed from GBGB9828506.7A external-priority patent/GB9828506D0/en
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of ATE336484T1 publication Critical patent/ATE336484T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT99940404T 1998-08-29 1999-08-24 Pyrimidine verbindungen ATE336484T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9818987.1A GB9818987D0 (en) 1998-08-29 1998-08-29 Chemical compounds
GBGB9828506.7A GB9828506D0 (en) 1998-12-24 1998-12-24 Chemical compounds

Publications (1)

Publication Number Publication Date
ATE336484T1 true ATE336484T1 (de) 2006-09-15

Family

ID=26314295

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99940404T ATE336484T1 (de) 1998-08-29 1999-08-24 Pyrimidine verbindungen

Country Status (9)

Country Link
US (1) US6632820B1 (de)
EP (1) EP1107958B1 (de)
JP (1) JP2002523498A (de)
AT (1) ATE336484T1 (de)
AU (1) AU5438499A (de)
DE (1) DE69932828T2 (de)
ES (1) ES2270612T3 (de)
HK (1) HK1035529A1 (de)
WO (1) WO2000012486A1 (de)

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US7129242B2 (en) 2000-12-06 2006-10-31 Signal Pharmaceuticals, Llc Anilinopyrimidine derivatives as JNK pathway inhibitors and compositions and methods related thereto
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GB0205688D0 (en) 2002-03-09 2002-04-24 Astrazeneca Ab Chemical compounds
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GB0311276D0 (en) 2003-05-16 2003-06-18 Astrazeneca Ab Chemical compounds
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US20090099160A1 (en) * 2004-12-17 2009-04-16 David Andrews 4-(4-(Imidazol-4-Yl) Pyrimidin-2-Ylamino) Benzamides as CDK Inhibitors
KR20080033450A (ko) * 2005-07-30 2008-04-16 아스트라제네카 아베 증식성 질환의 치료에 사용하기 위한 이미다졸릴-피리미딘화합물
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EA201491732A1 (ru) 2012-03-21 2015-08-31 Байер Интеллектуэль Проперти Гмбх Применение (rs)-s-циклопропил-s-(4-{[4-{[(1r,2r)-2-гидрокси-1-метилпропил]окси}-5-(трифторметил)пиримидин-2-ил]амино}фенил)сульфоксимида для лечения специфических опухолей
WO2014173815A1 (en) 2013-04-23 2014-10-30 Bayer Pharma Aktiengesellschaft Use of (rs)-s-cyclopropyl-s-(4-{[4-{[(1r, 2r)-2-hydroxy-1-methylpropyl]oxy}-5- (trifluoromethyl)pyrimidin-2-yl]amino}phenyl)sulphoximide for the treatment of specific tumours
CN106146478B (zh) * 2015-04-10 2019-07-16 海南轩竹医药科技有限公司 三嗪衍生物类间变性淋巴瘤激酶抑制剂

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Also Published As

Publication number Publication date
EP1107958B1 (de) 2006-08-16
US6632820B1 (en) 2003-10-14
DE69932828T2 (de) 2007-10-18
ES2270612T3 (es) 2007-04-01
DE69932828D1 (de) 2006-09-28
WO2000012486A1 (en) 2000-03-09
JP2002523498A (ja) 2002-07-30
EP1107958A1 (de) 2001-06-20
HK1035529A1 (en) 2001-11-30
AU5438499A (en) 2000-03-21

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Legal Events

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