PL176389B1 - Nowe pochodne ksantyny i środek leczniczy zwłaszcza o działaniu adenozynoantagonistycznym - Google Patents

Nowe pochodne ksantyny i środek leczniczy zwłaszcza o działaniu adenozynoantagonistycznym

Info

Publication number
PL176389B1
PL176389B1 PL93307397A PL30739793A PL176389B1 PL 176389 B1 PL176389 B1 PL 176389B1 PL 93307397 A PL93307397 A PL 93307397A PL 30739793 A PL30739793 A PL 30739793A PL 176389 B1 PL176389 B1 PL 176389B1
Authority
PL
Poland
Prior art keywords
cyclopentyl
formula
pattern
theory
benzyl
Prior art date
Application number
PL93307397A
Other languages
English (en)
Polish (pl)
Other versions
PL307397A1 (en
Inventor
Ulrike Küfner-Mühl
Helmut Ensinger
Joachim Mierau
Franz J. Kuhn
Erich Lehr
Enzio Müller
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of PL307397A1 publication Critical patent/PL307397A1/xx
Publication of PL176389B1 publication Critical patent/PL176389B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Laser Surgery Devices (AREA)
  • Radiation-Therapy Devices (AREA)
  • Thermotherapy And Cooling Therapy Devices (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
PL93307397A 1992-08-10 1993-08-05 Nowe pochodne ksantyny i środek leczniczy zwłaszcza o działaniu adenozynoantagonistycznym PL176389B1 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE4226371 1992-08-10
DE4238423 1992-11-13
PCT/EP1993/002077 WO1994003456A1 (de) 1992-08-10 1993-08-05 Unsymmetrisch substituierte xanthine mit adenosinantagonistischen eigenschaften

Publications (2)

Publication Number Publication Date
PL307397A1 PL307397A1 (en) 1995-05-15
PL176389B1 true PL176389B1 (pl) 1999-05-31

Family

ID=25917371

Family Applications (1)

Application Number Title Priority Date Filing Date
PL93307397A PL176389B1 (pl) 1992-08-10 1993-08-05 Nowe pochodne ksantyny i środek leczniczy zwłaszcza o działaniu adenozynoantagonistycznym

Country Status (21)

Country Link
US (1) US5719279A (OSRAM)
EP (1) EP0654033A1 (OSRAM)
JP (1) JPH08500344A (OSRAM)
KR (1) KR950702988A (OSRAM)
CN (1) CN1043348C (OSRAM)
AU (1) AU681348B2 (OSRAM)
BG (1) BG62618B1 (OSRAM)
CA (1) CA2140883A1 (OSRAM)
CZ (1) CZ286459B6 (OSRAM)
FI (1) FI950542A7 (OSRAM)
HU (1) HUT65734A (OSRAM)
IL (1) IL106624A (OSRAM)
MX (1) MX9304819A (OSRAM)
NZ (1) NZ254804A (OSRAM)
PL (1) PL176389B1 (OSRAM)
RU (1) RU2138500C1 (OSRAM)
SG (1) SG55038A1 (OSRAM)
SK (1) SK18595A3 (OSRAM)
TW (1) TW252044B (OSRAM)
UA (1) UA46697C2 (OSRAM)
WO (1) WO1994003456A1 (OSRAM)

Families Citing this family (85)

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DE60018216T2 (de) * 1999-12-24 2006-02-16 Kyowa Hakko Kogyo Co., Ltd. Kondensierte purinderivate
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KR20190016601A (ko) 2008-08-06 2019-02-18 베링거 인겔하임 인터내셔날 게엠베하 메트포르민 요법이 부적합한 환자에서의 당뇨병 치료
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KR20190050871A (ko) 2010-06-24 2019-05-13 베링거 인겔하임 인터내셔날 게엠베하 당뇨병 요법
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DK3517539T3 (en) 2011-07-15 2023-01-16 Boehringer Ingelheim Int Farmaceutiske sammensætninger til behandling af type i og type ii diabetes
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WO2013174767A1 (en) 2012-05-24 2013-11-28 Boehringer Ingelheim International Gmbh A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference
JP6615109B2 (ja) 2014-02-28 2019-12-04 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Ｄｐｐ−４阻害薬の医学的使用
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CN109796453A (zh) * 2019-02-12 2019-05-24 南京纽邦生物科技有限公司 一种1,7-二甲基黄嘌呤的制备方法
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Also Published As

Publication number Publication date
FI950542A0 (fi) 1995-02-08
FI950542L (fi) 1995-02-08
SK18595A3 (en) 1995-07-11
BG62618B1 (bg) 2000-03-31
CZ34895A3 (en) 1995-10-18
NZ254804A (en) 1997-01-29
HU9302302D0 (en) 1993-10-28
BG99489A (bg) 1996-01-31
TW252044B (OSRAM) 1995-07-21
JPH08500344A (ja) 1996-01-16
CA2140883A1 (en) 1994-02-17
KR950702988A (ko) 1995-08-23
US5719279A (en) 1998-02-17
WO1994003456A1 (de) 1994-02-17
PL307397A1 (en) 1995-05-15
CN1043348C (zh) 1999-05-12
HUT65734A (en) 1994-07-28
IL106624A0 (en) 1993-12-08
CZ286459B6 (en) 2000-04-12
FI950542A7 (fi) 1995-02-08
MX9304819A (es) 1994-02-28
IL106624A (en) 1999-01-26
SG55038A1 (en) 1998-12-21
CN1086818A (zh) 1994-05-18
UA46697C2 (uk) 2002-06-17
RU2138500C1 (ru) 1999-09-27
AU4707193A (en) 1994-03-03
AU681348B2 (en) 1997-08-28
RU95109100A (ru) 1996-12-27
EP0654033A1 (de) 1995-05-24

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