PL174312B1 - Nowy związek, kwas 4-chloro-5-trójpodstawiony sililo-2-tiofenokarboksylowy - Google Patents

Nowy związek, kwas 4-chloro-5-trójpodstawiony sililo-2-tiofenokarboksylowy

Info

Publication number
PL174312B1
PL174312B1 PL93309048A PL30904893A PL174312B1 PL 174312 B1 PL174312 B1 PL 174312B1 PL 93309048 A PL93309048 A PL 93309048A PL 30904893 A PL30904893 A PL 30904893A PL 174312 B1 PL174312 B1 PL 174312B1
Authority
PL
Poland
Prior art keywords
chloro
acid
formula
solution
compound
Prior art date
Application number
PL93309048A
Other languages
English (en)
Polish (pl)
Other versions
PL309048A1 (en
Inventor
Laurence E. Burgess
Gary R. Schulte
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of PL309048A1 publication Critical patent/PL309048A1/xx
Publication of PL174312B1 publication Critical patent/PL174312B1/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/0803Compounds with Si-C or Si-Si linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Catalysts (AREA)
  • Indole Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Paper (AREA)
  • Seasonings (AREA)
PL93309048A 1992-11-23 1993-09-17 Nowy związek, kwas 4-chloro-5-trójpodstawiony sililo-2-tiofenokarboksylowy PL174312B1 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US97998392A 1992-11-23 1992-11-23
PCT/US1993/008613 WO1994012505A1 (en) 1992-11-23 1993-09-17 Regioselective synthesis of 4-chloro-2-thiophenecarboxylic acid

Publications (2)

Publication Number Publication Date
PL309048A1 PL309048A1 (en) 1995-09-18
PL174312B1 true PL174312B1 (pl) 1998-07-31

Family

ID=25527268

Family Applications (1)

Application Number Title Priority Date Filing Date
PL93309048A PL174312B1 (pl) 1992-11-23 1993-09-17 Nowy związek, kwas 4-chloro-5-trójpodstawiony sililo-2-tiofenokarboksylowy

Country Status (26)

Country Link
US (1) US5648502A (zh)
EP (1) EP0669924B1 (zh)
JP (2) JP2706573B2 (zh)
KR (1) KR950704727A (zh)
CN (4) CN1036001C (zh)
AT (1) ATE146181T1 (zh)
AU (1) AU670454B2 (zh)
BR (1) BR9307503A (zh)
CA (1) CA2148616C (zh)
CZ (1) CZ131695A3 (zh)
DE (1) DE69306595T2 (zh)
DK (1) DK0669924T3 (zh)
EG (1) EG20200A (zh)
ES (1) ES2095080T3 (zh)
FI (1) FI935168A (zh)
GR (1) GR3022396T3 (zh)
HU (1) HUT68757A (zh)
IL (2) IL107612A0 (zh)
MX (1) MX9307292A (zh)
MY (1) MY109037A (zh)
NO (1) NO952021L (zh)
NZ (1) NZ256279A (zh)
PL (1) PL174312B1 (zh)
RU (1) RU2114854C1 (zh)
WO (1) WO1994012505A1 (zh)
ZA (1) ZA938705B (zh)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998045282A1 (en) * 1997-04-04 1998-10-15 Pfizer Inc. Processes and intermediates for preparing 2-fluorothiophene derivatives
CN100413861C (zh) * 2002-12-10 2008-08-27 维勒凯姆制药股份有限公司 用于治疗或预防黄病毒感染的化合物
US7560551B2 (en) 2006-01-23 2009-07-14 Amgen Inc. Aurora kinase modulators and method of use
AU2008299220B2 (en) * 2007-09-10 2011-07-21 Calcimedica, Inc. Compounds that modulate intracellular calcium
ITMI20071971A1 (it) * 2007-10-10 2009-04-11 Altergon Sa Composizione farmaceutica per la somministrazione sublinguale di progesterone, e metodo per la sua preparazione
US8389567B2 (en) 2007-12-12 2013-03-05 Calcimedica, Inc. Compounds that modulate intracellular calcium
MX2011002149A (es) 2008-08-27 2011-04-05 Calcimedica Inc Compuestos que modulan el calcio intracelular.
US8524763B2 (en) 2008-09-22 2013-09-03 Calcimedica, Inc. Inhibitors of store operated calcium release
US8143269B2 (en) 2008-10-03 2012-03-27 Calcimedica, Inc. Inhibitors of store operated calcium release
CN101987842A (zh) * 2009-07-31 2011-03-23 上海开拓者医药发展有限公司 一种2-甲基噻吩衍生物的制备方法
EP2477982A4 (en) 2009-09-16 2013-04-03 Calcimedica Inc COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM
CN103180316A (zh) 2010-08-27 2013-06-26 钙医学公司 调节细胞内钙的化合物
US9512116B2 (en) 2012-10-12 2016-12-06 Calcimedica, Inc. Compounds that modulate intracellular calcium
CN109096245A (zh) * 2018-09-27 2018-12-28 上海雅本化学有限公司 一种5-氯噻吩-2-甲酸的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4432974A (en) * 1982-03-04 1984-02-21 E. I. Du Pont De Nemours And Company Antiinflammatory and/or analgesic 2,3-diaryl-5-silyl thiophenes
DE3534286A1 (de) * 1985-09-26 1987-04-02 Hoechst Ag Verfahren zur herstellung von halogenthiophen-2-carbonsaeuren
SK278175B6 (en) * 1988-10-18 1996-03-06 Pfizer 3-acyl-2-oxindole-1-carboxamides and method of their preparation
US5047554A (en) * 1989-04-18 1991-09-10 Pfizer Inc. 3-substituted-2-oxindole derivatives
FR2655655A1 (fr) * 1989-12-07 1991-06-14 Rhone Poulenc Chimie Procede de preparation de polysilthiophenediyle et polymeres obtenus a l'issue de ce procede.
PL170837B1 (pl) * 1991-10-18 1997-01-31 Monsanto Co S rod ek g r zybobó j c zy PL PL PL PL PL PL

Also Published As

Publication number Publication date
FI935168A0 (fi) 1993-11-22
ES2095080T3 (es) 1997-02-01
CN1158853A (zh) 1997-09-10
ZA938705B (en) 1995-05-22
CN1158851A (zh) 1997-09-10
NO952021D0 (no) 1995-05-22
DK0669924T3 (da) 1997-06-16
AU670454B2 (en) 1996-07-18
MY109037A (en) 1996-11-30
NO952021L (no) 1995-05-22
JP2706573B2 (ja) 1998-01-28
CN1036001C (zh) 1997-10-01
GR3022396T3 (en) 1997-04-30
CN1093704A (zh) 1994-10-19
US5648502A (en) 1997-07-15
DE69306595T2 (de) 1997-04-03
CN1156725A (zh) 1997-08-13
EG20200A (en) 1997-10-30
FI935168A (fi) 1994-05-24
EP0669924B1 (en) 1996-12-11
KR950704727A (ko) 1995-11-20
DE69306595D1 (en) 1997-01-23
ATE146181T1 (de) 1996-12-15
PL309048A1 (en) 1995-09-18
CA2148616C (en) 1998-02-03
RU2114854C1 (ru) 1998-07-10
JPH1081683A (ja) 1998-03-31
BR9307503A (pt) 1999-06-29
IL120461A0 (en) 1997-07-13
HUT68757A (en) 1995-07-28
CZ131695A3 (en) 1996-05-15
AU4858793A (en) 1994-06-22
IL107612A0 (en) 1994-02-27
JP2795642B2 (ja) 1998-09-10
NZ256279A (en) 1996-11-26
EP0669924A1 (en) 1995-09-06
WO1994012505A1 (en) 1994-06-09
JPH07508761A (ja) 1995-09-28
CA2148616A1 (en) 1994-06-09
MX9307292A (es) 1994-05-31

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