IL120461A0 - Process for preparing 5-fluoro-6-chloro-3-(4-chloro-2-thenoyl)-2-oxindole-1-carboxamide - Google Patents

Process for preparing 5-fluoro-6-chloro-3-(4-chloro-2-thenoyl)-2-oxindole-1-carboxamide

Info

Publication number
IL120461A0
IL120461A0 IL12046197A IL12046197A IL120461A0 IL 120461 A0 IL120461 A0 IL 120461A0 IL 12046197 A IL12046197 A IL 12046197A IL 12046197 A IL12046197 A IL 12046197A IL 120461 A0 IL120461 A0 IL 120461A0
Authority
IL
Israel
Prior art keywords
chloro
pct
compound
thenoyl
oxindole
Prior art date
Application number
IL12046197A
Other languages
English (en)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IL120461A0 publication Critical patent/IL120461A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0803—Compounds with Si-C or Si-Si linkages
IL12046197A 1992-11-23 1997-03-17 Process for preparing 5-fluoro-6-chloro-3-(4-chloro-2-thenoyl)-2-oxindole-1-carboxamide IL120461A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US97998392A 1992-11-23 1992-11-23
IL10761293A IL107612A0 (en) 1992-11-23 1993-11-15 Regioselective synthesis of 4-chloro-2-thiophenecarboxylic acid

Publications (1)

Publication Number Publication Date
IL120461A0 true IL120461A0 (en) 1997-07-13

Family

ID=25527268

Family Applications (2)

Application Number Title Priority Date Filing Date
IL10761293A IL107612A0 (en) 1992-11-23 1993-11-15 Regioselective synthesis of 4-chloro-2-thiophenecarboxylic acid
IL12046197A IL120461A0 (en) 1992-11-23 1997-03-17 Process for preparing 5-fluoro-6-chloro-3-(4-chloro-2-thenoyl)-2-oxindole-1-carboxamide

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IL10761293A IL107612A0 (en) 1992-11-23 1993-11-15 Regioselective synthesis of 4-chloro-2-thiophenecarboxylic acid

Country Status (26)

Country Link
US (1) US5648502A (xx)
EP (1) EP0669924B1 (xx)
JP (2) JP2706573B2 (xx)
KR (1) KR950704727A (xx)
CN (4) CN1036001C (xx)
AT (1) ATE146181T1 (xx)
AU (1) AU670454B2 (xx)
BR (1) BR9307503A (xx)
CA (1) CA2148616C (xx)
CZ (1) CZ131695A3 (xx)
DE (1) DE69306595T2 (xx)
DK (1) DK0669924T3 (xx)
EG (1) EG20200A (xx)
ES (1) ES2095080T3 (xx)
FI (1) FI935168A (xx)
GR (1) GR3022396T3 (xx)
HU (1) HUT68757A (xx)
IL (2) IL107612A0 (xx)
MX (1) MX9307292A (xx)
MY (1) MY109037A (xx)
NO (1) NO952021L (xx)
NZ (1) NZ256279A (xx)
PL (1) PL174312B1 (xx)
RU (1) RU2114854C1 (xx)
WO (1) WO1994012505A1 (xx)
ZA (1) ZA938705B (xx)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6043379A (en) * 1997-04-04 2000-03-28 Pfizer Inc. Processes and intermediates for preparing 2-fluorothiophene derivatives
KR101058696B1 (ko) * 2002-12-10 2011-08-22 바이로켐 파마 인코포레이티드 후라비바이러스 감염의 치료 또는 예방을 위한 화합물과방법
US7560551B2 (en) 2006-01-23 2009-07-14 Amgen Inc. Aurora kinase modulators and method of use
CA2699157A1 (en) * 2007-09-10 2009-03-19 Calcimedica, Inc. Compounds that modulate intracellular calcium
ITMI20071971A1 (it) * 2007-10-10 2009-04-11 Altergon Sa Composizione farmaceutica per la somministrazione sublinguale di progesterone, e metodo per la sua preparazione
WO2009076454A2 (en) 2007-12-12 2009-06-18 Calcimedica, Inc. Compounds that modulate intracellular calcium
MY157445A (en) 2008-08-27 2016-06-15 Calcimedica Inc Compounds that modulate intracellular calcium.
US8524763B2 (en) 2008-09-22 2013-09-03 Calcimedica, Inc. Inhibitors of store operated calcium release
US8143269B2 (en) 2008-10-03 2012-03-27 Calcimedica, Inc. Inhibitors of store operated calcium release
CN101987842A (zh) * 2009-07-31 2011-03-23 上海开拓者医药发展有限公司 一种2-甲基噻吩衍生物的制备方法
EP2477982A4 (en) 2009-09-16 2013-04-03 Calcimedica Inc COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM
CA2809830C (en) 2010-08-27 2019-09-10 Calcimedica, Inc. Compounds comprising n-acyl-2-amino-1,3-thiazole for modulating intracellular calcium
US9512116B2 (en) 2012-10-12 2016-12-06 Calcimedica, Inc. Compounds that modulate intracellular calcium
CN109096245A (zh) * 2018-09-27 2018-12-28 上海雅本化学有限公司 一种5-氯噻吩-2-甲酸的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4432974A (en) * 1982-03-04 1984-02-21 E. I. Du Pont De Nemours And Company Antiinflammatory and/or analgesic 2,3-diaryl-5-silyl thiophenes
DE3534286A1 (de) * 1985-09-26 1987-04-02 Hoechst Ag Verfahren zur herstellung von halogenthiophen-2-carbonsaeuren
US5118703A (en) * 1988-10-18 1992-06-02 Pfizer Inc. Prodrugs of antiinflammatory 3-acyl-2-oxindole-1-carboxamides
US5047554A (en) * 1989-04-18 1991-09-10 Pfizer Inc. 3-substituted-2-oxindole derivatives
FR2655655A1 (fr) * 1989-12-07 1991-06-14 Rhone Poulenc Chimie Procede de preparation de polysilthiophenediyle et polymeres obtenus a l'issue de ce procede.
CA2119155C (en) * 1991-10-18 1999-06-15 Dennis Paul Phillion Fungicides for the control of take-all disease of plants

Also Published As

Publication number Publication date
ES2095080T3 (es) 1997-02-01
CA2148616C (en) 1998-02-03
CN1158853A (zh) 1997-09-10
EP0669924B1 (en) 1996-12-11
AU670454B2 (en) 1996-07-18
JPH07508761A (ja) 1995-09-28
NO952021D0 (no) 1995-05-22
JP2795642B2 (ja) 1998-09-10
PL174312B1 (pl) 1998-07-31
WO1994012505A1 (en) 1994-06-09
KR950704727A (ko) 1995-11-20
AU4858793A (en) 1994-06-22
CN1156725A (zh) 1997-08-13
CN1036001C (zh) 1997-10-01
GR3022396T3 (en) 1997-04-30
CN1093704A (zh) 1994-10-19
HUT68757A (en) 1995-07-28
US5648502A (en) 1997-07-15
CN1158851A (zh) 1997-09-10
NZ256279A (en) 1996-11-26
FI935168A0 (fi) 1993-11-22
CA2148616A1 (en) 1994-06-09
MY109037A (en) 1996-11-30
JP2706573B2 (ja) 1998-01-28
MX9307292A (es) 1994-05-31
BR9307503A (pt) 1999-06-29
CZ131695A3 (en) 1996-05-15
JPH1081683A (ja) 1998-03-31
EP0669924A1 (en) 1995-09-06
DE69306595T2 (de) 1997-04-03
PL309048A1 (en) 1995-09-18
DE69306595D1 (en) 1997-01-23
NO952021L (no) 1995-05-22
RU2114854C1 (ru) 1998-07-10
ZA938705B (en) 1995-05-22
DK0669924T3 (da) 1997-06-16
EG20200A (en) 1997-10-30
FI935168A (fi) 1994-05-24
ATE146181T1 (de) 1996-12-15
IL107612A0 (en) 1994-02-27

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