BR9307503A - Síntese regiosseletiva da ácido 4-cloro-2 tiofenocarboxícilo - Google Patents
Síntese regiosseletiva da ácido 4-cloro-2 tiofenocarboxíciloInfo
- Publication number
- BR9307503A BR9307503A BR9307503A BR9307503A BR9307503A BR 9307503 A BR9307503 A BR 9307503A BR 9307503 A BR9307503 A BR 9307503A BR 9307503 A BR9307503 A BR 9307503A BR 9307503 A BR9307503 A BR 9307503A
- Authority
- BR
- Brazil
- Prior art keywords
- pct
- chloro
- thiophenecarboxylic acid
- compound
- regioselective synthesis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US97998392A | 1992-11-23 | 1992-11-23 | |
| PCT/US1993/008613 WO1994012505A1 (en) | 1992-11-23 | 1993-09-17 | Regioselective synthesis of 4-chloro-2-thiophenecarboxylic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9307503A true BR9307503A (pt) | 1999-06-29 |
Family
ID=25527268
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9307503A BR9307503A (pt) | 1992-11-23 | 1993-09-17 | Síntese regiosseletiva da ácido 4-cloro-2 tiofenocarboxícilo |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US5648502A (pt) |
| EP (1) | EP0669924B1 (pt) |
| JP (2) | JP2706573B2 (pt) |
| KR (1) | KR950704727A (pt) |
| CN (4) | CN1036001C (pt) |
| AT (1) | ATE146181T1 (pt) |
| AU (1) | AU670454B2 (pt) |
| BR (1) | BR9307503A (pt) |
| CA (1) | CA2148616C (pt) |
| CZ (1) | CZ131695A3 (pt) |
| DE (1) | DE69306595T2 (pt) |
| DK (1) | DK0669924T3 (pt) |
| EG (1) | EG20200A (pt) |
| ES (1) | ES2095080T3 (pt) |
| FI (1) | FI935168A (pt) |
| GR (1) | GR3022396T3 (pt) |
| HU (1) | HUT68757A (pt) |
| IL (2) | IL107612A0 (pt) |
| MX (1) | MX9307292A (pt) |
| MY (1) | MY109037A (pt) |
| NO (1) | NO952021L (pt) |
| NZ (1) | NZ256279A (pt) |
| PL (1) | PL174312B1 (pt) |
| RU (1) | RU2114854C1 (pt) |
| WO (1) | WO1994012505A1 (pt) |
| ZA (1) | ZA938705B (pt) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6043379A (en) * | 1997-04-04 | 2000-03-28 | Pfizer Inc. | Processes and intermediates for preparing 2-fluorothiophene derivatives |
| DE60332482D1 (de) * | 2002-12-10 | 2010-06-17 | Virochem Pharma Inc | Verbindungen und methoden zum behandeln oder vorbeugen von flavivirus infektionen |
| US7560551B2 (en) | 2006-01-23 | 2009-07-14 | Amgen Inc. | Aurora kinase modulators and method of use |
| JP5411141B2 (ja) | 2007-09-10 | 2014-02-12 | カルシメディカ，インク． | 細胞内カルシウムを調節する化合物 |
| ITMI20071971A1 (it) * | 2007-10-10 | 2009-04-11 | Altergon Sa | Composizione farmaceutica per la somministrazione sublinguale di progesterone, e metodo per la sua preparazione |
| US8389567B2 (en) | 2007-12-12 | 2013-03-05 | Calcimedica, Inc. | Compounds that modulate intracellular calcium |
| WO2010027875A2 (en) | 2008-08-27 | 2010-03-11 | Calcimedica Inc. | Compounds that modulate intracellular calcium |
| US8524763B2 (en) | 2008-09-22 | 2013-09-03 | Calcimedica, Inc. | Inhibitors of store operated calcium release |
| US8143269B2 (en) | 2008-10-03 | 2012-03-27 | Calcimedica, Inc. | Inhibitors of store operated calcium release |
| CN101987842A (zh) * | 2009-07-31 | 2011-03-23 | 上海开拓者医药发展有限公司 | 一种2-甲基噻吩衍生物的制备方法 |
| WO2011034962A2 (en) | 2009-09-16 | 2011-03-24 | Calcimedica Inc. | Compounds that modulate intracellular calcium |
| MX337711B (es) | 2010-08-27 | 2016-03-15 | Calcimedica Inc | Compuestos que modulan el calcio intracelular. |
| WO2014059333A1 (en) | 2012-10-12 | 2014-04-17 | Calcimedica, Inc. | Compounds that modulate intracellular calcium |
| CN109096245A (zh) * | 2018-09-27 | 2018-12-28 | 上海雅本化学有限公司 | 一种5-氯噻吩-2-甲酸的制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4432974A (en) * | 1982-03-04 | 1984-02-21 | E. I. Du Pont De Nemours And Company | Antiinflammatory and/or analgesic 2,3-diaryl-5-silyl thiophenes |
| DE3534286A1 (de) * | 1985-09-26 | 1987-04-02 | Hoechst Ag | Verfahren zur herstellung von halogenthiophen-2-carbonsaeuren |
| SK590689A3 (en) * | 1988-10-18 | 1996-03-06 | Pfizer | 3-aryl-2-oxindole-1-carboxamides and method of their preparation |
| US5047554A (en) * | 1989-04-18 | 1991-09-10 | Pfizer Inc. | 3-substituted-2-oxindole derivatives |
| FR2655655A1 (fr) * | 1989-12-07 | 1991-06-14 | Rhone Poulenc Chimie | Procede de preparation de polysilthiophenediyle et polymeres obtenus a l'issue de ce procede. |
| SK44894A3 (en) * | 1991-10-18 | 1995-04-12 | Monsanto Co | Trisubstituted aromatic compounds, method of their preparation and fungicidal agents |
-
1993
- 1993-09-17 CZ CZ951316A patent/CZ131695A3/cs unknown
- 1993-09-17 ES ES93921527T patent/ES2095080T3/es not_active Expired - Lifetime
- 1993-09-17 WO PCT/US1993/008613 patent/WO1994012505A1/en not_active Application Discontinuation
- 1993-09-17 JP JP6513105A patent/JP2706573B2/ja not_active Expired - Lifetime
- 1993-09-17 DK DK93921527.3T patent/DK0669924T3/da active
- 1993-09-17 BR BR9307503A patent/BR9307503A/pt not_active Application Discontinuation
- 1993-09-17 PL PL93309048A patent/PL174312B1/pl unknown
- 1993-09-17 CA CA002148616A patent/CA2148616C/en not_active Expired - Fee Related
- 1993-09-17 DE DE69306595T patent/DE69306595T2/de not_active Expired - Fee Related
- 1993-09-17 KR KR1019950702059A patent/KR950704727A/ko active IP Right Grant
- 1993-09-17 AU AU48587/93A patent/AU670454B2/en not_active Ceased
- 1993-09-17 EP EP93921527A patent/EP0669924B1/en not_active Expired - Lifetime
- 1993-09-17 RU RU95112836A patent/RU2114854C1/ru active
- 1993-09-17 NZ NZ256279A patent/NZ256279A/en unknown
- 1993-09-17 AT AT93921527T patent/ATE146181T1/de not_active IP Right Cessation
- 1993-09-17 US US08/436,415 patent/US5648502A/en not_active Expired - Fee Related
- 1993-11-15 IL IL10761293A patent/IL107612A0/xx unknown
- 1993-11-19 MY MYPI93002430A patent/MY109037A/en unknown
- 1993-11-21 EG EG73493A patent/EG20200A/xx active
- 1993-11-21 ZA ZA938705A patent/ZA938705B/xx unknown
- 1993-11-22 CN CN93114714A patent/CN1036001C/zh not_active Expired - Fee Related
- 1993-11-22 HU HU9303311A patent/HUT68757A/hu unknown
- 1993-11-22 MX MX9307292A patent/MX9307292A/es not_active IP Right Cessation
- 1993-11-22 FI FI935168A patent/FI935168A/fi not_active Application Discontinuation
-
1995
- 1995-05-22 NO NO952021A patent/NO952021L/no unknown
-
1996
- 1996-11-08 CN CN96114451A patent/CN1158851A/zh active Pending
- 1996-11-08 CN CN96114452A patent/CN1158853A/zh active Pending
- 1996-11-08 CN CN96114450A patent/CN1156725A/zh active Pending
-
1997
- 1997-01-29 GR GR960403453T patent/GR3022396T3/el unknown
- 1997-03-17 IL IL12046197A patent/IL120461A0/xx unknown
- 1997-07-02 JP JP9176977A patent/JP2795642B2/ja not_active Expired - Lifetime
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR9307503A (pt) | Síntese regiosseletiva da ácido 4-cloro-2 tiofenocarboxícilo | |
| CA2304713A1 (en) | Biphenyl-5-alkanoic acid derivatives and use thereof | |
| HUP0303043A2 (hu) | Orrgyógyászatilag aktív vegyületek | |
| DK0654041T3 (da) | Peptidyl-4-amino-2,2-difluor-3-oxo-1,6-hexandisyre-derivater som anto-inflammatoriske midler | |
| ES2003671A6 (es) | Un procedimiento para preparar derivados de dihidrobenzo-furano- y cromano-carboxamidas | |
| HUP0004731A2 (hu) | 2-Aril-benzo[b]tiofének alkalmazása ösztrogén elvonási szindróma kezelésére alkalmas gyógyszerkészítmények előállítására | |
| WO2002020525A3 (en) | Protein tyrosine phosphatase inhibitor | |
| AU6709896A (en) | Quinone compound, its production and use | |
| FI955837A0 (fi) | Menetelmä suun kautta annettavan, kiinteän, diklofenaakkia sisältävän annostelumuodon valmistamiseksi | |
| IL112432A0 (en) | Fatty acid derivatives, methods for the preparation thereof and pharmaceutical compositions containing the same | |
| KR950700913A (ko) | 브릿지된 비스-아릴 카비놀 유도체, 조성물 및 사용방법(Bridged bis arylcarbinol derivatives, compositions and methods of use) | |
| ATE112552T1 (de) | Harnstoffderivate, ihre herstellung und deren enthaltende arzneimittel. | |
| EA200000389A3 (ru) | Новые замещенные пиридины или пиперидины, способ их получения и содержащие их фармацевтические композиции | |
| FI950892A0 (fi) | Entsymaattinen asymmetrinen pelkistysmenetelmä 4-H-tieno-(2,3-6) tiopyraanijohdannaisten tuottamiseksi | |
| EA199600007A2 (ru) | Новые трициклические производные, способ их получения, способы получения оптически активных или рацемических колхицина и тиоколхицина, их аналогов или производных с использованием трициклических соединений и промежуточные продукты синтеза | |
| IL107520A0 (en) | Substituted ortho-ethenylphenylacetic acid derivatives and pharmaceutical compositions containing them | |
| ES2041679T3 (es) | Compuestos analgesicos de octohidroindolizinas 5-substituidas y productos intermedios 7-ceto. | |
| PT1047664E (pt) | Novos compostos triciclicos processo para a sua preparacao e as composicoes farmaceuticas que os contem | |
| FR2696454B1 (fr) | Procédé de préparation stéréosélective d'un dérivé de la beta-phénylisosérine et son utilisation pour la préparation de dérivés du Taxane. | |
| DE69406451T2 (de) | Verfahren zur herstellung von n-carbonylarylimine als zwischenprodukte in der synthese von therapeutisch aktiven taxol-derivaten | |
| KR970701188A (ko) | 엔케팔리나제 및 안지오텐신 전환 효소(ACE)의 억제제로서 유용한 신규의 머캅토아세틸아미드 디설파이드 유도체(Novel mercaptoacetylamide disulfide derivatives useful as inhibitors of enkephalinase and ACE) | |
| DE59403736D1 (de) | 3-halogen-3-hetarylcarbonsäurederivate, verfahren und zwischenprodukte zu ihrer herstellung |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EG | Technical examination (opinion): publication of technical examination (opinion) | ||
| FC | Decision: refusal |