PL121778B1 - Process for preparing novel derivatives of/d,l/-9-ketoprostatrienic acidatrienovojj kisloty - Google Patents

Process for preparing novel derivatives of/d,l/-9-ketoprostatrienic acidatrienovojj kisloty Download PDF

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Publication number
PL121778B1
PL121778B1 PL1979217001A PL21700179A PL121778B1 PL 121778 B1 PL121778 B1 PL 121778B1 PL 1979217001 A PL1979217001 A PL 1979217001A PL 21700179 A PL21700179 A PL 21700179A PL 121778 B1 PL121778 B1 PL 121778B1
Authority
PL
Poland
Prior art keywords
compounds
formula
acid
keto
phenoxy
Prior art date
Application number
PL1979217001A
Other languages
English (en)
Polish (pl)
Other versions
PL217001A1 (enExample
Inventor
Albert R Van Horn
Gabriel Saray
John A Edwards
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of PL217001A1 publication Critical patent/PL217001A1/xx
Publication of PL121778B1 publication Critical patent/PL121778B1/pl

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PL1979217001A 1978-07-10 1979-07-10 Process for preparing novel derivatives of/d,l/-9-ketoprostatrienic acidatrienovojj kisloty PL121778B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/922,957 US4178457A (en) 1978-07-10 1978-07-10 (dl)-16-Phenoxy- and 16-substituted phenoxy-9-keto prostatrienoic acid derivatives and processes for the production thereof

Publications (2)

Publication Number Publication Date
PL217001A1 PL217001A1 (enExample) 1980-03-24
PL121778B1 true PL121778B1 (en) 1982-05-31

Family

ID=25447871

Family Applications (4)

Application Number Title Priority Date Filing Date
PL1979217001A PL121778B1 (en) 1978-07-10 1979-07-10 Process for preparing novel derivatives of/d,l/-9-ketoprostatrienic acidatrienovojj kisloty
PL1979224555A PL120604B1 (en) 1978-07-10 1979-07-10 Process for preparing novel derivative of/d,1/-9-keto-prostatrienic acidtrienovojj kisloty
PL1979224557A PL120632B1 (en) 1978-07-10 1979-07-10 Process for preparing novel derivative of/d,1/-9-keto-prostatrienic acidtrienovojj kisloty
PL1979224556A PL120633B1 (en) 1978-07-10 1979-07-10 Process for preparing novel derivatives of/d,1/-9-keto-prostatrienic acidatrienovojj kisloty

Family Applications After (3)

Application Number Title Priority Date Filing Date
PL1979224555A PL120604B1 (en) 1978-07-10 1979-07-10 Process for preparing novel derivative of/d,1/-9-keto-prostatrienic acidtrienovojj kisloty
PL1979224557A PL120632B1 (en) 1978-07-10 1979-07-10 Process for preparing novel derivative of/d,1/-9-keto-prostatrienic acidtrienovojj kisloty
PL1979224556A PL120633B1 (en) 1978-07-10 1979-07-10 Process for preparing novel derivatives of/d,1/-9-keto-prostatrienic acidatrienovojj kisloty

Country Status (26)

Country Link
US (1) US4178457A (enExample)
EP (1) EP0008003B1 (enExample)
JP (1) JPS5513282A (enExample)
KR (1) KR890002773B1 (enExample)
AT (1) ATE2427T1 (enExample)
AU (1) AU527516B2 (enExample)
CA (1) CA1149802A (enExample)
CS (1) CS209927B2 (enExample)
DD (1) DD146179A5 (enExample)
DE (2) DE2964709D1 (enExample)
DK (1) DK157753C (enExample)
ES (1) ES482330A1 (enExample)
FI (1) FI69061C (enExample)
FR (1) FR2430939A1 (enExample)
GB (1) GB2025413B (enExample)
HK (1) HK41384A (enExample)
HU (1) HU184185B (enExample)
IT (1) IT1121462B (enExample)
MY (1) MY8500576A (enExample)
NO (4) NO150836C (enExample)
NZ (1) NZ190924A (enExample)
PL (4) PL121778B1 (enExample)
SG (1) SG82483G (enExample)
SU (1) SU1031407A3 (enExample)
YU (3) YU41870B (enExample)
ZA (1) ZA793293B (enExample)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4328245A (en) * 1981-02-13 1982-05-04 Syntex (U.S.A.) Inc. Carbonate diester solutions of PGE-type compounds
US4358603A (en) * 1981-04-16 1982-11-09 Syntex (U.S.A.) Inc. Acetal stabilized prostaglandin compositions
US4409239A (en) * 1982-01-21 1983-10-11 Syntex (U.S.A.) Inc. Propylene glycol diester solutions of PGE-type compounds
US4804787A (en) * 1983-12-22 1989-02-14 Syntex (U.S.A.) Inc. Processes and intermediates for making 16-phenoxy and 16-substituted phenoxy-prostatrienoic acid derivatives
US4600785A (en) * 1983-12-22 1986-07-15 Syntex (U.S.A.) Inc. Processes and intermediates for making 16-phenoxy and 16-substituted phenoxy-prostatrienoic acid derivatives
US4912235A (en) * 1983-12-22 1990-03-27 Syntex (U.S.A.) Inc. Processes and intermediates for making 16-phenoxy- and 16-substituted phenoxy-prostatrienoic acid derivatives and their stereoisomers
DE3414509A1 (de) * 1984-04-13 1985-10-24 Schering AG, 1000 Berlin und 4709 Bergkamen Neue 9-halogen-prostaglandine
US5057621A (en) * 1984-07-31 1991-10-15 Syntex (U.S.A.) Inc. 11-substituted-16-phenoxy and 16-substituted phenoxy-prostatrienoic acid derivatives
US4792617A (en) * 1984-07-31 1988-12-20 Syntex (U.S.A.) Inc. 11-substituted-16-phenoxy and 16-substituted phenoxy-prostatrienioc acid derivatives
JPS6147459A (ja) * 1984-07-31 1986-03-07 シンテツクス（ユー・エス・エイ）インコーポレイテツド １１−置換−１６−フエノキシプロスタトリエン酸誘導体
US4618696A (en) * 1984-07-31 1986-10-21 Syntex (U.S.A.) Inc. 9-oxo-15α-hydroxy-16-phenoxy and 16-substituted phenoxy 17,18,19,20-tetranorprosta-4,5,13,(E)-trienoates
US4778904A (en) * 1985-09-13 1988-10-18 Syntex (U.S.A.) Inc. Intermediates for making 16-phenoxy- and 16-(substituted phenoxy)-prostatrienoic acid derivatives
JPS62267231A (ja) * 1986-04-11 1987-11-19 シンテツクス（ユ−・エス・エイ）　インコ−ポレイテツド 脂肪および炭水化物代謝調節剤エンプロスチル型プロスタグランジン類
US4755531A (en) * 1986-08-11 1988-07-05 Syntex (U.S.A.) Inc. Thiol esters of 4,5-allenyl prostaglandins and use thereof as antigastric secretion agents
GB8625321D0 (en) * 1986-10-22 1986-11-26 Glaxo Group Ltd Chemical compounds
US4689419A (en) * 1986-11-14 1987-08-25 G. D. Searle & Co. Novel intermediate compounds in a process for producing 16-phenoxy- and 16-substituted phenoxy-9-keto-prostatrienoic acid derivatives
US6103765A (en) * 1997-07-09 2000-08-15 Androsolutions, Inc. Methods for treating male erectile dysfunction
WO1999002147A1 (en) 1997-07-09 1999-01-21 Androsolutions, Inc. Improved methods and compositions for treating male erectile dysfunction
US20020013294A1 (en) 2000-03-31 2002-01-31 Delong Mitchell Anthony Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives
US20020037914A1 (en) 2000-03-31 2002-03-28 Delong Mitchell Anthony Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins
US20020172693A1 (en) 2000-03-31 2002-11-21 Delong Michell Anthony Compositions and methods for treating hair loss using non-naturally occurring prostaglandins
US8966971B2 (en) * 2008-07-28 2015-03-03 Ford Global Technologies, Llc Vehicle engine with fluid measuring system
WO2010096123A2 (en) * 2008-10-29 2010-08-26 Aerie Pharmaceuticals, Inc. Amino acid salts of prostaglandins
US8623918B2 (en) 2008-10-29 2014-01-07 Novaer Holdings, Inc. Amino acid salts of prostaglandins
US8722739B2 (en) 2008-10-29 2014-05-13 Novaer Holdings, Inc. Amino acid salts of prostaglandins
US20110293549A1 (en) 2009-02-03 2011-12-01 Athena Cosmetics, Inc. Composition, method and kit for enhancing hair

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES449162A1 (es) * 1975-06-23 1977-12-16 Syntex Inc Un procedimiento para la preparacion de un compuesto racemi-co u 8r-antimerico.

Also Published As

Publication number Publication date
EP0008003A1 (en) 1980-02-20
SG82483G (en) 1984-08-03
IT7968428A0 (it) 1979-07-09
NO152296C (no) 1985-09-04
YU73586A (en) 1986-12-31
PL120604B1 (en) 1982-03-31
HU184185B (en) 1984-07-30
DE2927715A1 (de) 1980-01-24
KR890002773B1 (ko) 1989-07-28
JPS5513282A (en) 1980-01-30
DK157753C (da) 1990-07-09
EP0008003B1 (en) 1983-02-09
US4178457A (en) 1979-12-11
YU168579A (en) 1983-02-28
DK157753B (da) 1990-02-12
GB2025413A (en) 1980-01-23
NO152296B (no) 1985-05-28
YU41870B (en) 1988-02-29
NO840258L (no) 1980-01-11
NO840257L (no) 1980-01-11
NO152211B (no) 1985-05-13
PL217001A1 (enExample) 1980-03-24
FI69061B (fi) 1985-08-30
NO152212B (no) 1985-05-13
NZ190924A (en) 1980-11-28
ES482330A1 (es) 1980-08-16
CS209927B2 (en) 1981-12-31
NO840256L (no) 1980-01-11
NO152212C (no) 1985-08-21
DD146179A5 (de) 1981-01-28
YU44553B (en) 1990-08-31
PL120632B1 (en) 1982-03-31
FI792149A7 (fi) 1980-01-11
AU4864179A (en) 1980-02-07
NO150836C (no) 1985-01-09
AU527516B2 (en) 1983-03-10
CA1149802A (en) 1983-07-12
NO150836B (no) 1984-09-17
HK41384A (en) 1984-05-18
YU44554B (en) 1990-08-31
FI69061C (fi) 1985-12-10
FR2430939B1 (enExample) 1981-08-14
YU73686A (en) 1986-12-31
MY8500576A (en) 1985-12-31
ZA793293B (en) 1981-02-25
DE2927715C2 (enExample) 1987-08-27
SU1031407A3 (ru) 1983-07-23
NO152211C (no) 1985-08-21
DK288879A (da) 1980-01-11
ATE2427T1 (de) 1983-03-15
NO792283L (no) 1980-01-11
GB2025413B (en) 1982-07-28
DE2964709D1 (en) 1983-03-17
FR2430939A1 (fr) 1980-02-08
PL120633B1 (en) 1982-03-31
IT1121462B (it) 1986-04-02
JPS6210227B2 (enExample) 1987-03-05

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