PH19293A - Epimeric azahomoerythromycin,pharmaceutical composition containing the same and method of use thereof - Google Patents

Epimeric azahomoerythromycin,pharmaceutical composition containing the same and method of use thereof

Info

Publication number
PH19293A
PH19293A PH29751A PH29751A PH19293A PH 19293 A PH19293 A PH 19293A PH 29751 A PH29751 A PH 29751A PH 29751 A PH29751 A PH 29751A PH 19293 A PH19293 A PH 19293A
Authority
PH
Philippines
Prior art keywords
azahomoerythromycin
epimeric
pharmaceutical composition
same
composition containing
Prior art date
Application number
PH29751A
Other languages
English (en)
Inventor
Gene Michael Brighrt
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of PH19293A publication Critical patent/PH19293A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cosmetics (AREA)
  • Developing Agents For Electrophotography (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
PH29751A 1982-11-15 1983-10-21 Epimeric azahomoerythromycin,pharmaceutical composition containing the same and method of use thereof PH19293A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US44197982A 1982-11-15 1982-11-15

Publications (1)

Publication Number Publication Date
PH19293A true PH19293A (en) 1986-03-04

Family

ID=23755068

Family Applications (2)

Application Number Title Priority Date Filing Date
PH29751A PH19293A (en) 1982-11-15 1983-10-21 Epimeric azahomoerythromycin,pharmaceutical composition containing the same and method of use thereof
PH31922A PH21560A (en) 1982-11-15 1985-02-28 Epimeric azahomoerythromycin a, derivatives and intermediate therefor

Family Applications After (1)

Application Number Title Priority Date Filing Date
PH31922A PH21560A (en) 1982-11-15 1985-02-28 Epimeric azahomoerythromycin a, derivatives and intermediate therefor

Country Status (26)

Country Link
EP (1) EP0109253B1 (no)
JP (1) JPS59104398A (no)
KR (1) KR850000968B1 (no)
AT (1) ATE30237T1 (no)
AU (1) AU544790B2 (no)
CA (1) CA1239639A (no)
CS (1) CS241069B2 (no)
DD (1) DD216017A5 (no)
DE (1) DE3374065D1 (no)
DK (1) DK159322C (no)
EG (1) EG16641A (no)
ES (2) ES8600327A1 (no)
FI (1) FI72980C (no)
GR (1) GR79425B (no)
GT (1) GT198304062A (no)
HU (1) HU193886B (no)
IE (1) IE56234B1 (no)
IL (1) IL70228A (no)
NO (1) NO160262C (no)
NZ (1) NZ206259A (no)
PH (2) PH19293A (no)
PL (2) PL142601B1 (no)
PT (1) PT77645B (no)
SU (1) SU1272996A3 (no)
YU (2) YU43198B (no)
ZA (1) ZA838460B (no)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4465674A (en) * 1983-09-06 1984-08-14 Pfizer Inc. Azahomoerythromycin D derivative and intermediates therefor
ATE38519T1 (de) * 1983-09-06 1988-11-15 Pfizer Azahomoerythromycin-b-derivate und zwischenprodukte.
RU2066324C1 (ru) * 1987-07-09 1996-09-10 Пфайзер Инк. Кристаллический дигидрат азитромицина и способ его получения
WO1989002271A1 (en) * 1987-09-10 1989-03-23 Pfizer Azithromycin and derivatives as antiprotozoal agents
JP2751385B2 (ja) * 1988-05-19 1998-05-18 大正製薬株式会社 エリスロマイシンａオキシム及びその塩の製造方法
US5075289A (en) * 1988-06-07 1991-12-24 Abbott Laboratories 9-r-azacyclic erythromycin antibiotics
SI8911498B (sl) * 1989-07-26 1998-10-31 Pliva Postopek za pripravo derivatov tilozina
US5912331A (en) * 1991-03-15 1999-06-15 Merck & Co., Inc. Process for the preparation of 9-deoxo-9(Z)-hydroxyiminoerythromycin A
CA2064634C (en) * 1991-04-04 1998-08-04 James V. Heck 9-deoxo-8a-aza-8a-homoerythromycin a derivatives modified at the 4"- and8a-positions
US5985844A (en) * 1992-03-26 1999-11-16 Merck & Co., Inc. Homoerythromycin A derivatives modified at the 4"-and 8A-positions
CA2064985A1 (en) * 1991-04-05 1992-10-06 Robert R. Wilkening 8a-aza-8a-homoertyhromycin cyclic lactams
CA2065222A1 (en) * 1991-04-09 1992-10-10 Robert R. Wilkening Process for the preparation of 8a-aza-8a-homoerythromycin cyclic iminoethers
EP0508795A1 (en) * 1991-04-10 1992-10-14 Merck & Co. Inc. 8a-aza-8a-homoerythromycin cyclic iminoethers
US5189159A (en) * 1992-04-02 1993-02-23 Merck & Co., Inc. 8a-AZA-8a-homoerythromycin cyclic iminoethers
CA2065218A1 (en) * 1991-04-11 1992-10-12 Robert R. Wilkening Process for the preparation of 9-deoxo-8a-aza-8a-homoerythromycin a and its 8a-alkyl derivatives
CA2068951A1 (en) * 1991-05-20 1992-11-21 Robert R. Wilkening Process for the preparation of 8a-aza-8a-homoerythromycin cyclic lactams
EP0549040A1 (en) * 1991-12-20 1993-06-30 Merck & Co. Inc. Methods of making 4" derivatives of 9-deoxo-8a-aza-8a-alkyl-8a-homoerythromycin A
US5215980A (en) * 1992-01-17 1993-06-01 Merck & Co., Inc. 10-AZA-9-deoxo-11-deoxy-erythromycin A and derivatives thereof
US5210235A (en) * 1992-08-26 1993-05-11 Merck & Co., Inc. Methods of elaborating erythromycin fragments into amine-containing fragments of azalide antibiotics
HRP930014A2 (en) * 1993-01-08 1994-08-31 Pliva Pharm & Chem Works 9-deoxo-9a-aza-11-deoxy-9a-homoeritromycin a 9a, 11-cyclic carbamates
US5332807A (en) * 1993-04-14 1994-07-26 Merck & Co., Inc. Process of producing 8A- and 9A-azalide antibiotics
ES2163504T5 (es) 1994-05-06 2008-05-16 Pfizer Inc. Formas de dosificacion de liberacion controlada de azitromicina.
PT102006B (pt) * 1997-05-19 2000-06-30 Hovione Sociedade Quimica S A Novo processo de preparacao de azitromicina
TW546302B (en) 1998-05-08 2003-08-11 Biochemie Sa Improvements in macrolide production
EP1437360A3 (en) * 1998-08-19 2005-04-06 Pfizer Products Inc. C11 Carbamates of macrolide antibacterials
US6043227A (en) * 1998-08-19 2000-03-28 Pfizer Inc. C11 carbamates of macrolide antibacterials
US6764996B1 (en) 1999-08-24 2004-07-20 Abbott Laboratories 9a-azalides with antibacterial activity
BR0009101A (pt) * 1999-08-24 2002-02-05 Abbott Lab 9a-azalidas com atividade antibacteriana
CA2396426A1 (en) * 2000-01-04 2001-07-12 Teva Pharmaceutical Industries Ltd. Preparation method of azithromycin dihydrate
EP1313749B1 (en) 2000-08-23 2005-10-12 Wockhardt Limited Process for preparation of anhydrous azithromycin
US6852262B2 (en) 2002-05-09 2005-02-08 The Gillette Company Insert molding razor cartridges
WO2005053652A1 (en) 2003-12-04 2005-06-16 Pfizer Products Inc. Multiparticulate crystalline drug compositions containing a poloxamer and a glyceride
CA2547774A1 (en) 2003-12-04 2005-06-16 Pfizer Products Inc. Method for making pharmaceutical multiparticulates
JP2007513139A (ja) 2003-12-04 2007-05-24 ファイザー・プロダクツ・インク 安定性の改善した多粒子組成物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU43116B (en) * 1979-04-02 1989-04-30 Pliva Pharm & Chem Works Process for preparing 11-aza-4-o-cladinosyl-6-o-desosaminyl-15-ethyl-7,13,14-trihydroxy-3,5,7,9,12,14-hexamethyl-oxacyclopentadecane-2-one(11-aza-10-deox
JPS5788193A (en) * 1980-11-21 1982-06-01 Pliva Pharm & Chem Works 11-aza-10-deoxo-10-dihydroerythromycin a, derivatives and manufacture
SI8110592A8 (en) * 1981-03-06 1996-06-30 Pliva Pharm & Chem Works Process for preparing of n-methyl-11-aza-10-deoxo-10-dihydroerythromycine a and derivatives thereof
US4382085A (en) * 1982-03-01 1983-05-03 Pfizer Inc. 4"-Epi erythromycin A and derivatives thereof as useful antibacterial agents

Also Published As

Publication number Publication date
DK159322B (da) 1990-10-01
PL244557A1 (en) 1985-03-26
DD216017A5 (de) 1984-11-28
ATE30237T1 (de) 1987-10-15
NO160262B (no) 1988-12-19
HU193886B (en) 1987-12-28
DK518683A (da) 1984-05-16
YU43198B (en) 1989-04-30
YU43425B (en) 1989-06-30
FI834163A (fi) 1984-05-16
ES543638A0 (es) 1986-01-16
IL70228A0 (en) 1984-02-29
ZA838460B (en) 1985-06-26
CA1239639A (en) 1988-07-26
KR850000968B1 (ko) 1985-07-02
PH21560A (en) 1987-12-11
AU544790B2 (en) 1985-06-13
PT77645A (en) 1983-12-01
EG16641A (en) 1990-08-30
ES527249A0 (es) 1985-10-01
FI72980C (fi) 1987-08-10
NO834146L (no) 1984-05-16
PT77645B (en) 1986-05-12
CS241069B2 (en) 1986-03-13
JPS59104398A (ja) 1984-06-16
PL142601B1 (en) 1987-11-30
DE3374065D1 (en) 1987-11-19
FI834163A0 (fi) 1983-11-14
NO160262C (no) 1989-03-29
IE832652L (en) 1984-05-15
EP0109253A3 (en) 1984-09-12
IL70228A (en) 1987-03-31
EP0109253A2 (en) 1984-05-23
AU2130983A (en) 1984-05-24
CS845583A2 (en) 1985-07-16
GR79425B (no) 1984-10-22
EP0109253B1 (en) 1987-10-14
ES8604257A1 (es) 1986-01-16
ES8600327A1 (es) 1985-10-01
YU224383A (en) 1986-04-30
HUT35273A (en) 1985-06-28
DK518683D0 (da) 1983-11-14
NZ206259A (en) 1986-08-08
FI72980B (fi) 1987-04-30
PL143281B1 (en) 1988-01-30
IE56234B1 (en) 1991-05-22
SU1272996A3 (ru) 1986-11-23
YU197285A (en) 1986-08-31
GT198304062A (es) 1985-05-04
JPH0140038B2 (no) 1989-08-24
DK159322C (da) 1991-02-25
KR840006673A (ko) 1984-12-01
PL250350A1 (en) 1985-04-24

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