PH14220A - 2-acyl-4-oxo-pyrazino-isoquinolines - Google Patents

2-acyl-4-oxo-pyrazino-isoquinolines

Info

Publication number
PH14220A
PH14220A PH16619A PH16619A PH14220A PH 14220 A PH14220 A PH 14220A PH 16619 A PH16619 A PH 16619A PH 16619 A PH16619 A PH 16619A PH 14220 A PH14220 A PH 14220A
Authority
PH
Philippines
Prior art keywords
isoquinolines
pyrazino
oxo
acyl
Prior art date
Application number
PH16619A
Other languages
English (en)
Inventor
J Seubert
P Andress
H Thomas
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=5900929&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PH14220(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of PH14220A publication Critical patent/PH14220A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
PH16619A 1973-12-17 1974-12-12 2-acyl-4-oxo-pyrazino-isoquinolines PH14220A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2362539A DE2362539C2 (de) 1973-12-17 1973-12-17 2-Acyl-4-oxo-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isochinoline, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
PH14220A true PH14220A (en) 1981-04-02

Family

ID=5900929

Family Applications (1)

Application Number Title Priority Date Filing Date
PH16619A PH14220A (en) 1973-12-17 1974-12-12 2-acyl-4-oxo-pyrazino-isoquinolines

Country Status (35)

Country Link
US (1) US4001411A (de)
JP (1) JPS5826352B2 (de)
AR (2) AR208527A1 (de)
AT (1) AT346334B (de)
BE (1) BE823400A (de)
CA (1) CA1036606A (de)
CH (3) CH612195A5 (de)
CS (1) CS241002B2 (de)
DD (1) DD115908A5 (de)
DE (1) DE2362539C2 (de)
DK (1) DK141845C (de)
ES (2) ES432974A1 (de)
FI (1) FI59594C (de)
FR (1) FR2254343B1 (de)
GB (1) GB1441554A (de)
GR (1) GR60708B (de)
GT (1) GT197850798A (de)
HK (1) HK13379A (de)
HU (1) HU170858B (de)
IE (1) IE40124B1 (de)
IL (1) IL46162A (de)
IN (1) IN139511B (de)
IT (1) IT7851978A0 (de)
KE (1) KE2946A (de)
LU (1) LU71204A1 (de)
NL (1) NL185406C (de)
NO (1) NO142304C (de)
OA (1) OA04868A (de)
PH (1) PH14220A (de)
PL (3) PL99088B1 (de)
RO (1) RO66907A (de)
SE (1) SE422211B (de)
SU (3) SU631070A3 (de)
YU (1) YU41288B (de)
ZA (1) ZA747253B (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4196291A (en) * 1973-12-17 1980-04-01 Merck Patent Gesellschaft Mit Beschraenkter Haftung 2-Acyl-4-oxo-pyrazino-isoquinoline derivatives and process for the preparation thereof
US4141978A (en) * 1973-12-17 1979-02-27 Merck Patent Gesellschaft Mit Beschrankter Haftung 2-Acyl-4-oxo-pyrazino-isoquinoline derivatives and process for the preparation thereof
US4162319A (en) * 1974-08-28 1979-07-24 Merck Patent Gesellschaft Mit Beschrankter Haftung Ring substituted pyrazino-isoquinoline derivatives and their preparation
US4120961A (en) * 1974-08-28 1978-10-17 E. Merck Ring substituted pyrazino-isoquinoline derivatives and their preparation
DE2441261A1 (de) * 1974-08-28 1976-03-18 Merck Patent Gmbh Ringsubstituierte pyrazino-isochinolin-derivat und verfahren zu ihrer herstellung
DE2841668A1 (de) * 1978-09-25 1980-04-10 Bayer Ag Medikiertes tierfutter auf basis lebermehl
US4303659A (en) 1979-08-22 1981-12-01 Pfizer Inc. Schistosomicidal compositions
FR2520740A1 (fr) * 1982-01-29 1983-08-05 Sanofi Sa Procede pour la preparation d'acyl-2-hexahydro-1,3,4,6,7,11b-2h-pyrazino (2,1-a) isoquinoleinones-4 et intermediaires
DE3472678D1 (de) * 1983-07-18 1988-08-18 Beecham Group Plc Benzazepine and benzoxazepine derivatives
DE3634755A1 (de) * 1986-10-11 1988-04-14 Bayer Ag Dermale behandlung von wurmerkrankungen der katze mit praziquantel
NZ247278A (en) * 1991-02-12 1995-03-28 Ancare Distributors Veterinary anthelmintic drench comprising a suspension of praziquantel in a liquid carrier
DE19628776A1 (de) 1996-07-17 1998-01-22 Bayer Ag Oral applizierbare Granulate von Hexahydropyrazinderivaten
US6429211B1 (en) 2000-05-23 2002-08-06 Bayer Corporation Praziquantel compounds for treating diseases due to Sarcocystis Neospora Toxoplasma and Isospora
US7396819B2 (en) * 2003-08-08 2008-07-08 Virbac Corporation Anthelmintic formulations
DE10358525A1 (de) * 2003-12-13 2005-07-07 Bayer Healthcare Ag Endoparasitizide Mittel zur topischen Applikation
RU2266906C1 (ru) * 2004-04-29 2005-12-27 Общество с ограниченной ответственностью "Исследовательский Институт Химического Разнообразия" (ООО "Исследовательский Институт Химического Разнообразия") Анелированные карбамоилазагетероциклы, способы их получения (варианты), фармацевтическая композиция, фокусированная библиотека
DE102004055316A1 (de) * 2004-11-16 2006-05-18 Bayer Healthcare Ag Verhinderung vertikaler Endoparasiten-Infektionen
KR100682506B1 (ko) * 2005-01-18 2007-02-15 (주)젠크로스 프라지콴텔, 또는 이의 염을 포함하는 약학 조성물
DE102005011779A1 (de) * 2005-03-11 2006-09-14 Bayer Healthcare Ag Endoparasitizide Mittel
CA2609574A1 (en) * 2005-06-09 2006-12-21 Schering-Plough Ltd. Control of parasites in animals by n-[(phenyloxy)phenyl]-1,1,1-trifluoromethanesulfonamide and n-[(phenylsulfanyl)phenyl]-1,1,1-trifluoromethanesulfonamide derivatives
FR2912145B1 (fr) * 2007-02-02 2009-03-06 Servier Lab Nouveaux derives tricycliques,leur procede de preparation et les compositions pharmaceutiques qui les contiennent
ITPD20070274A1 (it) * 2007-08-08 2009-02-09 Sanypet S P A Crocchetta per animali e metodo per la sua produzione
CA2702577A1 (en) 2007-10-15 2009-04-23 Jbs United, Inc. Method for increasing performance of offspring
DE102008022520A1 (de) 2008-05-07 2009-11-12 Bayer Animal Health Gmbh Feste Arzneimittelformulierung mit verzögerter Freisetzung
AP2909A (en) 2009-03-17 2014-05-31 Concert Pharmaceuticals Inc Pyrazinoisoquinoline Compounds
CN102093346B (zh) * 2010-03-16 2012-09-05 浙江金伯士药业有限公司 一种吡喹酮的制备方法
WO2012122028A2 (en) 2011-03-04 2012-09-13 Concert Pharmaceuticals Inc. Pyrazinoisoquinoline compounds
CN103910725B (zh) * 2013-01-09 2015-12-02 江南大学 一类吡喹酮类似物、其制备方法和用途

Also Published As

Publication number Publication date
DK654274A (de) 1975-08-25
CA1036606A (en) 1978-08-15
SU625613A3 (ru) 1978-09-25
NO744521L (de) 1975-07-14
DE2362539A1 (de) 1975-08-28
IT7851978A0 (it) 1978-11-20
JPS5093999A (de) 1975-07-26
FI59594C (fi) 1981-09-10
RO66907A (ro) 1981-06-26
US4001411A (en) 1977-01-04
GB1441554A (en) 1976-07-07
ZA747253B (en) 1975-11-26
IE40124B1 (en) 1979-03-14
NL7416432A (nl) 1975-06-19
NL185406C (nl) 1990-04-02
SU631070A3 (ru) 1978-10-30
ATA996274A (de) 1978-03-15
JPS5826352B2 (ja) 1983-06-02
CH621788A5 (de) 1981-02-27
CH612195A5 (de) 1979-07-13
FR2254343A1 (de) 1975-07-11
IL46162A0 (en) 1975-02-10
PL94074B1 (de) 1977-07-30
AT346334B (de) 1978-11-10
NO142304C (no) 1980-07-30
OA04868A (fr) 1980-10-31
YU41288B (en) 1987-02-28
ES441546A1 (es) 1977-04-16
GR60708B (en) 1978-07-24
LU71204A1 (de) 1975-04-17
IE40124L (en) 1975-06-17
PL99105B1 (pl) 1978-06-30
IL46162A (en) 1979-01-31
DD115908A5 (de) 1975-10-20
SE422211B (sv) 1982-02-22
GT197850798A (es) 1979-08-01
AR208527A1 (es) 1977-02-15
SU668603A3 (ru) 1979-06-15
SE7415686L (de) 1975-06-18
FI59594B (fi) 1981-05-29
DK141845B (da) 1980-06-30
KE2946A (en) 1979-04-12
FR2254343B1 (de) 1978-06-30
ES432974A1 (es) 1977-02-16
FI363274A (de) 1975-06-18
BE823400A (fr) 1975-06-16
CH620442A5 (de) 1980-11-28
DK141845C (da) 1980-12-22
YU336174A (en) 1983-01-21
CS842774A2 (en) 1985-06-13
AR208715A1 (es) 1977-02-28
CS241002B2 (en) 1986-03-13
DE2362539C2 (de) 1986-05-07
PL99088B1 (pl) 1978-06-30
AU7643874A (en) 1976-06-17
HK13379A (en) 1979-03-23
HU170858B (hu) 1977-09-28
NL185406B (nl) 1989-11-01
IN139511B (de) 1976-06-26
NO142304B (no) 1980-04-21

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