PA8799401A1 - Uso de un beta bloqueante para la fabricacion de un medicamento para el tratamiento de los hemangiomas - Google Patents

Uso de un beta bloqueante para la fabricacion de un medicamento para el tratamiento de los hemangiomas

Info

Publication number
PA8799401A1
PA8799401A1 PA20088799401A PA8799401A PA8799401A1 PA 8799401 A1 PA8799401 A1 PA 8799401A1 PA 20088799401 A PA20088799401 A PA 20088799401A PA 8799401 A PA8799401 A PA 8799401A PA 8799401 A1 PA8799401 A1 PA 8799401A1
Authority
PA
Panama
Prior art keywords
hemangioms
treatment
manufacture
medicinal product
blocking beta
Prior art date
Application number
PA20088799401A
Other languages
English (en)
Inventor
Christine Leaute-Labreze
De La Roque Eric Dumas
Alain Taieb
Jean-Benoit Thambo
Original Assignee
Univ Victor Segalen Bordeaux 2
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39156667&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PA8799401(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Victor Segalen Bordeaux 2 filed Critical Univ Victor Segalen Bordeaux 2
Publication of PA8799401A1 publication Critical patent/PA8799401A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/222—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A61K31/36—Compounds containing methylenedioxyphenyl groups, e.g. sesamin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4704—2-Quinolinones, e.g. carbostyril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Otolaryngology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)

Abstract

LA PRESENTE INVENCIÓN SE REFIERE AL USO DE UN BETA BLOQUEANTE PARA LA FABRICACIÓN DE UN MEDICAMENTO PARA EL TRATAMIENTO DE LOS HEMANGIOMAS, POR EJEMPLO DE UN LOS HEMANGIOMAS INFANTILES. EL BETA BLOQUEANTE PUEDE SER UN BETA BLOQUEANTE NO SELECTIVO, POR EJEMPLO PROPANOLOL. LA PRESENTE INVENCIÓN PROPORCIONA UNA ALTERNATIVA A LOS COMPUESTOS CONOCIDOS, POR EJ., CORTICOIDES, INTERFERÓN O VINCRISTINA, QUE SE USAN GENERALMENTE PARA EL TRATAMIENTO DE LOS HEMANGIOMAS.
PA20088799401A 2007-10-19 2008-10-16 Uso de un beta bloqueante para la fabricacion de un medicamento para el tratamiento de los hemangiomas PA8799401A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07291273A EP2050441A1 (en) 2007-10-19 2007-10-19 Use of beta blocker for the manufacture of a medicament for the treatment of hemangiomas
US98950707P 2007-11-21 2007-11-21

Publications (1)

Publication Number Publication Date
PA8799401A1 true PA8799401A1 (es) 2009-05-15

Family

ID=39156667

Family Applications (1)

Application Number Title Priority Date Filing Date
PA20088799401A PA8799401A1 (es) 2007-10-19 2008-10-16 Uso de un beta bloqueante para la fabricacion de un medicamento para el tratamiento de los hemangiomas

Country Status (31)

Country Link
US (2) US8338489B2 (es)
EP (3) EP2050441A1 (es)
JP (1) JP5552700B2 (es)
KR (2) KR20150110827A (es)
CN (2) CN103169971A (es)
AR (1) AR068927A1 (es)
AT (1) ATE512661T1 (es)
AU (1) AU2008313405B2 (es)
BR (1) BRPI0816536A2 (es)
CA (1) CA2701953C (es)
CL (1) CL2008003083A1 (es)
CO (1) CO6270209A2 (es)
CY (1) CY1112604T1 (es)
DE (1) DE08838691T1 (es)
DK (2) DK2233135T3 (es)
ES (2) ES2390534T3 (es)
HK (1) HK1148940A1 (es)
HR (2) HRP20110659T1 (es)
IL (1) IL205129A (es)
MA (1) MA31843B1 (es)
MX (1) MX2010004295A (es)
MY (1) MY156750A (es)
NZ (1) NZ584307A (es)
PA (1) PA8799401A1 (es)
PL (2) PL2233135T3 (es)
PT (2) PT2187878E (es)
RU (1) RU2471500C2 (es)
SI (2) SI2187878T1 (es)
TN (1) TN2010000170A1 (es)
TW (1) TWI531365B (es)
WO (1) WO2009050567A2 (es)

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US8987262B2 (en) 2007-10-19 2015-03-24 Universite de Bordeaux Use of a beta blocker for the manufacture of a medicament for the treatment of hemangiomas
EP2050441A1 (en) 2007-10-19 2009-04-22 Université Victor Segalen Bordeaux 2 Use of beta blocker for the manufacture of a medicament for the treatment of hemangiomas
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CN103536607A (zh) * 2012-07-10 2014-01-29 邵金辉 土霉素，普罗帕酮和安乃近的抗肿瘤作用
CN103054793B (zh) * 2013-01-05 2015-01-21 广州军区广州总医院 一种用于治疗婴幼儿血管瘤的盐酸普萘洛尔乳膏及其制备方法
WO2014150899A1 (en) * 2013-03-15 2014-09-25 Chapin Matthew J Topical ophthalmic formulations for treating migraine
CN104274390B (zh) * 2014-09-04 2017-06-13 郑家伟 一种噻吗洛尔长效透皮制剂及其在血管瘤中的应用
RU2584082C1 (ru) * 2015-01-21 2016-05-20 Ильдар Наилевич Нурмеев Способ лечения гемангиом
CN105434337B (zh) * 2015-04-03 2019-08-16 武汉科福新药有限责任公司 盐酸普萘洛尔亚微乳凝胶及其制备方法和用途
CN105106105A (zh) * 2015-08-14 2015-12-02 天津市聚星康华医药科技有限公司 噻吗洛尔外用制剂治疗婴幼儿血管瘤的应用及其制备方法
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RU2617516C1 (ru) * 2016-03-24 2017-04-25 Государственное бюджетное учреждение здравоохранения города Москвы Научно-исследовательский институт неотложной детской хирургии и травматологии Департамента здравоохранения города Москвы Способ лечения младенческих гемангиом
CN106474061B (zh) * 2016-12-08 2019-01-22 黑龙江童医生儿童生物制药有限公司 一种盐酸普萘洛尔口服乳剂及其制备方法
CN108261411B (zh) * 2016-12-30 2021-04-30 武汉科福新药有限责任公司 用于婴幼儿血管瘤治疗的口腔膜剂及其制备方法
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CN108299279B (zh) * 2018-02-09 2021-03-23 北京梅尔森医药技术开发有限公司 取代芳基胺醇化合物及其制备方法和用途
CN110314154A (zh) * 2018-03-28 2019-10-11 武汉恒信源药业有限公司 左旋普萘洛尔在制备治疗血管病变药物中的应用
US20210346319A1 (en) * 2018-10-04 2021-11-11 Emory University Pharmaceutical Compositions of R-(+)-Propranolol in Enantiomeric Excess and Therapeutic Uses Related Thereto
RU2701213C1 (ru) * 2018-12-27 2019-09-25 Федеральное государственное бюджетное образовательное учреждение высшего образования "Российский национальный исследовательский медицинский университет имени Н.И. Пирогова" Министерства здравоохранения Российской Федерации (ФГБОУ ВО РНИМУ им. Н.И. Пирогова Минздрава России) Способ лечения инфантильных гемангиом
US11154518B2 (en) * 2018-12-28 2021-10-26 Chang Gung Memorial Hospital, Linkou Methods and apparatus for treating a wound
WO2020242962A1 (en) * 2019-05-24 2020-12-03 Pediatric Derm Developement Llc Treatment of infantile hemangioma
CN111773226A (zh) * 2019-06-26 2020-10-16 首都医科大学附属北京儿童医院 噻吗洛尔或其盐在制备预防和/或治疗丛状血管瘤的药物中的用途
CA3166161A1 (en) * 2020-01-29 2021-08-05 Paul Frank Davis Methods and compositions for the treatment of hemangioma
TWI776584B (zh) * 2020-07-10 2022-09-01 長庚醫療財團法人林口長庚紀念醫院 β-1腎上腺素受體拮抗劑用於製備減少表皮生長因子受體抑制劑誘導的上皮細胞損傷以及抑制癌細胞的組合物之用途
EP4223283A1 (en) 2020-09-30 2023-08-09 Nissan Chemical Corporation Water-soluble complex containing beta- blocker and lecithin
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Also Published As

Publication number Publication date
HRP20120765T1 (hr) 2012-10-31
ES2368299T3 (es) 2011-11-16
KR101562627B1 (ko) 2015-10-22
US8338489B2 (en) 2012-12-25
EP2187878B1 (en) 2011-06-15
EP2233135B8 (en) 2013-07-10
JP5552700B2 (ja) 2014-07-16
CN103169971A (zh) 2013-06-26
EP2050441A1 (en) 2009-04-22
CN102006864B (zh) 2013-01-16
SI2187878T1 (sl) 2011-10-28
AU2008313405B2 (en) 2013-12-19
RU2471500C2 (ru) 2013-01-10
PT2233135E (pt) 2012-09-06
KR20150110827A (ko) 2015-10-02
BRPI0816536A2 (pt) 2017-06-06
EP2233135B1 (en) 2012-06-27
TW200932207A (en) 2009-08-01
KR20100087012A (ko) 2010-08-02
RU2010112816A (ru) 2011-11-27
EP2187878A2 (en) 2010-05-26
CO6270209A2 (es) 2011-04-20
CL2008003083A1 (es) 2009-03-06
MA31843B1 (fr) 2010-11-01
HK1148940A1 (en) 2011-09-23
WO2009050567A2 (en) 2009-04-23
ES2390534T3 (es) 2012-11-13
PL2187878T3 (pl) 2012-01-31
TWI531365B (zh) 2016-05-01
CA2701953A1 (en) 2009-04-23
AU2008313405A1 (en) 2009-04-23
IL205129A0 (en) 2010-11-30
EP2233135A1 (en) 2010-09-29
PT2187878E (pt) 2011-09-07
IL205129A (en) 2015-05-31
US20100273889A1 (en) 2010-10-28
US20130072551A1 (en) 2013-03-21
US9173858B2 (en) 2015-11-03
DK2187878T3 (da) 2011-09-19
WO2009050567A3 (en) 2009-06-18
CY1112604T1 (el) 2016-02-10
TN2010000170A1 (en) 2011-11-11
MY156750A (en) 2016-03-31
DE08838691T1 (de) 2010-08-26
ATE512661T1 (de) 2011-07-15
CN102006864A (zh) 2011-04-06
DK2233135T3 (da) 2012-10-01
PL2233135T3 (pl) 2012-11-30
AR068927A1 (es) 2009-12-16
CA2701953C (en) 2015-05-19
JP2011500661A (ja) 2011-01-06
NZ584307A (en) 2012-03-30
HRP20110659T1 (hr) 2011-10-31
MX2010004295A (es) 2010-08-02
SI2233135T1 (sl) 2012-10-30

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