CY1112604T1 - Χρηση ενος βητα αποκλειστη για την παρασκευη ενος φαρμακου για τη θεραπεια αιμαγγειωματων - Google Patents

Χρηση ενος βητα αποκλειστη για την παρασκευη ενος φαρμακου για τη θεραπεια αιμαγγειωματων

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Publication number
CY1112604T1
CY1112604T1 CY20111100858T CY111100858T CY1112604T1 CY 1112604 T1 CY1112604 T1 CY 1112604T1 CY 20111100858 T CY20111100858 T CY 20111100858T CY 111100858 T CY111100858 T CY 111100858T CY 1112604 T1 CY1112604 T1 CY 1112604T1
Authority
CY
Cyprus
Prior art keywords
beta
treatment
exclusive
medicine
preparation
Prior art date
Application number
CY20111100858T
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English (en)
Inventor
Christine Léauté-Labrèze
De La Roque Éric Dumas
Alain Taieb
Jean-Benoît Thambo
Original Assignee
Université Bordeaux Segalen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39156667&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1112604(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Université Bordeaux Segalen filed Critical Université Bordeaux Segalen
Publication of CY1112604T1 publication Critical patent/CY1112604T1/el

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/18Sulfonamides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/222Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A61K31/36Compounds containing methylenedioxyphenyl groups, e.g. sesamin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/4045Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/47042-Quinolinones, e.g. carbostyril
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Otolaryngology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)

Abstract

Η παρούσα εφεύρεση σχετίζεται με τη χρήση ενός βήτα αποκλειστή για την παρασκευή ενός φαρμάκου για τη θεραπεία αιμαγγειωμάτων, για παράδειγμα βρεφικών αιμαγγειωμάτων. Ο βήτα αποκλειστής μπορεί να είναι μη εκλεκτικός βήτα-αποκλειστής, για παράδειγμα προπρανολόλη. Η παρούσα εφεύρεση παρέχει εναλλακτική πρόταση στις γνωστές ενώσεις, π.χ. κορτικοστεροειδή, ιντερφερόνη ή βινκριστίνη, που γενικά χρησιμοποιούνται για τη θεραπεία των αιμαγγειωμάτων.
CY20111100858T 2007-10-19 2011-09-07 Χρηση ενος βητα αποκλειστη για την παρασκευη ενος φαρμακου για τη θεραπεια αιμαγγειωματων CY1112604T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07291273A EP2050441A1 (en) 2007-10-19 2007-10-19 Use of beta blocker for the manufacture of a medicament for the treatment of hemangiomas
US98950707P 2007-11-21 2007-11-21
EP08838691A EP2187878B1 (en) 2007-10-19 2008-10-16 Use of a beta blocker for the manufacture of a medicament for the treatment of hemangiomas

Publications (1)

Publication Number Publication Date
CY1112604T1 true CY1112604T1 (el) 2016-02-10

Family

ID=39156667

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20111100858T CY1112604T1 (el) 2007-10-19 2011-09-07 Χρηση ενος βητα αποκλειστη για την παρασκευη ενος φαρμακου για τη θεραπεια αιμαγγειωματων

Country Status (31)

Country Link
US (2) US8338489B2 (el)
EP (3) EP2050441A1 (el)
JP (1) JP5552700B2 (el)
KR (2) KR101562627B1 (el)
CN (2) CN102006864B (el)
AR (1) AR068927A1 (el)
AT (1) ATE512661T1 (el)
AU (1) AU2008313405B2 (el)
BR (1) BRPI0816536A2 (el)
CA (1) CA2701953C (el)
CL (1) CL2008003083A1 (el)
CO (1) CO6270209A2 (el)
CY (1) CY1112604T1 (el)
DE (1) DE08838691T1 (el)
DK (2) DK2233135T3 (el)
ES (2) ES2368299T3 (el)
HK (1) HK1148940A1 (el)
HR (2) HRP20110659T1 (el)
IL (1) IL205129A (el)
MA (1) MA31843B1 (el)
MX (1) MX2010004295A (el)
MY (1) MY156750A (el)
NZ (1) NZ584307A (el)
PA (1) PA8799401A1 (el)
PL (2) PL2187878T3 (el)
PT (2) PT2187878E (el)
RU (1) RU2471500C2 (el)
SI (2) SI2187878T1 (el)
TN (1) TN2010000170A1 (el)
TW (1) TWI531365B (el)
WO (1) WO2009050567A2 (el)

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CN108299279B (zh) * 2018-02-09 2021-03-23 北京梅尔森医药技术开发有限公司 取代芳基胺醇化合物及其制备方法和用途
CN110314154A (zh) * 2018-03-28 2019-10-11 武汉恒信源药业有限公司 左旋普萘洛尔在制备治疗血管病变药物中的应用
WO2020072311A1 (en) * 2018-10-04 2020-04-09 Emory University Pharmaceutical compositions of r-(+)-propranolol in enantiomeric excess and therapeutic uses related thereto
RU2701213C1 (ru) * 2018-12-27 2019-09-25 Федеральное государственное бюджетное образовательное учреждение высшего образования "Российский национальный исследовательский медицинский университет имени Н.И. Пирогова" Министерства здравоохранения Российской Федерации (ФГБОУ ВО РНИМУ им. Н.И. Пирогова Минздрава России) Способ лечения инфантильных гемангиом
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CN111773226A (zh) * 2019-06-26 2020-10-16 首都医科大学附属北京儿童医院 噻吗洛尔或其盐在制备预防和/或治疗丛状血管瘤的药物中的用途
JP2023512252A (ja) * 2020-01-29 2023-03-24 ギリーズ マキンドー リサーチ インスティテュート 血管腫の治療のための方法および組成物
WO2022007878A1 (zh) * 2020-07-10 2022-01-13 长庚医疗财团法人林口长庚纪念医院 β-1肾上腺素受体拮抗剂用于制备减少表皮生长因子受体抑制剂诱导的上皮细胞损伤以及抑制癌细胞的组合物的用途
CN116472036A (zh) * 2020-09-30 2023-07-21 日产化学株式会社 包含水溶性β阻断剂及卵磷脂的复合体
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Also Published As

Publication number Publication date
CN102006864B (zh) 2013-01-16
KR101562627B1 (ko) 2015-10-22
US20100273889A1 (en) 2010-10-28
US9173858B2 (en) 2015-11-03
PT2233135E (pt) 2012-09-06
PL2187878T3 (pl) 2012-01-31
IL205129A0 (en) 2010-11-30
MA31843B1 (fr) 2010-11-01
DE08838691T1 (de) 2010-08-26
US20130072551A1 (en) 2013-03-21
EP2187878A2 (en) 2010-05-26
RU2471500C2 (ru) 2013-01-10
EP2233135B1 (en) 2012-06-27
CA2701953C (en) 2015-05-19
CL2008003083A1 (es) 2009-03-06
CA2701953A1 (en) 2009-04-23
HK1148940A1 (en) 2011-09-23
EP2233135A1 (en) 2010-09-29
WO2009050567A3 (en) 2009-06-18
JP2011500661A (ja) 2011-01-06
TN2010000170A1 (en) 2011-11-11
RU2010112816A (ru) 2011-11-27
NZ584307A (en) 2012-03-30
DK2233135T3 (da) 2012-10-01
CN102006864A (zh) 2011-04-06
PA8799401A1 (es) 2009-05-15
ES2368299T3 (es) 2011-11-16
EP2187878B1 (en) 2011-06-15
CO6270209A2 (es) 2011-04-20
BRPI0816536A2 (pt) 2017-06-06
PT2187878E (pt) 2011-09-07
AU2008313405B2 (en) 2013-12-19
MX2010004295A (es) 2010-08-02
CN103169971A (zh) 2013-06-26
WO2009050567A2 (en) 2009-04-23
KR20150110827A (ko) 2015-10-02
SI2187878T1 (sl) 2011-10-28
EP2050441A1 (en) 2009-04-22
US8338489B2 (en) 2012-12-25
AR068927A1 (es) 2009-12-16
SI2233135T1 (sl) 2012-10-30
HRP20120765T1 (hr) 2012-10-31
PL2233135T3 (pl) 2012-11-30
JP5552700B2 (ja) 2014-07-16
AU2008313405A1 (en) 2009-04-23
MY156750A (en) 2016-03-31
HRP20110659T1 (hr) 2011-10-31
KR20100087012A (ko) 2010-08-02
EP2233135B8 (en) 2013-07-10
ES2390534T3 (es) 2012-11-13
DK2187878T3 (da) 2011-09-19
TW200932207A (en) 2009-08-01
TWI531365B (zh) 2016-05-01
ATE512661T1 (de) 2011-07-15
IL205129A (en) 2015-05-31

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