DK2187878T3 - Anvendelse af en betablokker til fremstilling af et medikament til behandling af hæmangiomer - Google Patents
Anvendelse af en betablokker til fremstilling af et medikament til behandling af hæmangiomerInfo
- Publication number
- DK2187878T3 DK2187878T3 DK08838691.7T DK08838691T DK2187878T3 DK 2187878 T3 DK2187878 T3 DK 2187878T3 DK 08838691 T DK08838691 T DK 08838691T DK 2187878 T3 DK2187878 T3 DK 2187878T3
- Authority
- DK
- Denmark
- Prior art keywords
- hemangiomas
- blocker
- medicament
- beta
- manufacture
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/222—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
- A61K31/36—Compounds containing methylenedioxyphenyl groups, e.g. sesamin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07291273A EP2050441A1 (en) | 2007-10-19 | 2007-10-19 | Use of beta blocker for the manufacture of a medicament for the treatment of hemangiomas |
US98950707P | 2007-11-21 | 2007-11-21 | |
PCT/IB2008/002746 WO2009050567A2 (en) | 2007-10-19 | 2008-10-16 | Use of a beta blocker for the manufacture of a medicament for the treatment of hemangiomas |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2187878T3 true DK2187878T3 (da) | 2011-09-19 |
Family
ID=39156667
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK08838691.7T DK2187878T3 (da) | 2007-10-19 | 2008-10-16 | Anvendelse af en betablokker til fremstilling af et medikament til behandling af hæmangiomer |
DK09015563.1T DK2233135T3 (da) | 2007-10-19 | 2008-10-16 | Anvendelse af en betablokker til fremstilling af et medikament til behandling af hæmangiomer |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK09015563.1T DK2233135T3 (da) | 2007-10-19 | 2008-10-16 | Anvendelse af en betablokker til fremstilling af et medikament til behandling af hæmangiomer |
Country Status (31)
Country | Link |
---|---|
US (2) | US8338489B2 (da) |
EP (3) | EP2050441A1 (da) |
JP (1) | JP5552700B2 (da) |
KR (2) | KR101562627B1 (da) |
CN (2) | CN103169971A (da) |
AR (1) | AR068927A1 (da) |
AT (1) | ATE512661T1 (da) |
AU (1) | AU2008313405B2 (da) |
BR (1) | BRPI0816536A2 (da) |
CA (1) | CA2701953C (da) |
CL (1) | CL2008003083A1 (da) |
CO (1) | CO6270209A2 (da) |
CY (1) | CY1112604T1 (da) |
DE (1) | DE08838691T1 (da) |
DK (2) | DK2187878T3 (da) |
ES (2) | ES2390534T3 (da) |
HK (1) | HK1148940A1 (da) |
HR (2) | HRP20110659T1 (da) |
IL (1) | IL205129A (da) |
MA (1) | MA31843B1 (da) |
MX (1) | MX2010004295A (da) |
MY (1) | MY156750A (da) |
NZ (1) | NZ584307A (da) |
PA (1) | PA8799401A1 (da) |
PL (2) | PL2187878T3 (da) |
PT (2) | PT2233135E (da) |
RU (1) | RU2471500C2 (da) |
SI (2) | SI2187878T1 (da) |
TN (1) | TN2010000170A1 (da) |
TW (1) | TWI531365B (da) |
WO (1) | WO2009050567A2 (da) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2050441A1 (en) | 2007-10-19 | 2009-04-22 | Université Victor Segalen Bordeaux 2 | Use of beta blocker for the manufacture of a medicament for the treatment of hemangiomas |
US8987262B2 (en) | 2007-10-19 | 2015-03-24 | Universite de Bordeaux | Use of a beta blocker for the manufacture of a medicament for the treatment of hemangiomas |
US8633181B2 (en) * | 2009-04-09 | 2014-01-21 | Rutgers, The State University Of New Jersey | Treatment of cutaneous hemangioma |
EP2246044A1 (en) | 2009-04-21 | 2010-11-03 | Pierre Fabre Dermo-Cosmétique | Paediatric solutions comprising a beta-blocker |
WO2012125413A2 (en) * | 2011-03-12 | 2012-09-20 | Vicus Therapeutics, Llc | Compositions for ameliorating systemic inflammation and methods for making and using them |
CN102579412A (zh) * | 2012-02-16 | 2012-07-18 | 山东省立医院 | 一种治疗婴幼儿血管瘤的外用药物及其制备方法 |
CN103536607A (zh) * | 2012-07-10 | 2014-01-29 | 邵金辉 | 土霉素,普罗帕酮和安乃近的抗肿瘤作用 |
CN103054793B (zh) * | 2013-01-05 | 2015-01-21 | 广州军区广州总医院 | 一种用于治疗婴幼儿血管瘤的盐酸普萘洛尔乳膏及其制备方法 |
WO2014150899A1 (en) * | 2013-03-15 | 2014-09-25 | Chapin Matthew J | Topical ophthalmic formulations for treating migraine |
CN104274390B (zh) * | 2014-09-04 | 2017-06-13 | 郑家伟 | 一种噻吗洛尔长效透皮制剂及其在血管瘤中的应用 |
RU2584082C1 (ru) * | 2015-01-21 | 2016-05-20 | Ильдар Наилевич Нурмеев | Способ лечения гемангиом |
CN105434337B (zh) * | 2015-04-03 | 2019-08-16 | 武汉科福新药有限责任公司 | 盐酸普萘洛尔亚微乳凝胶及其制备方法和用途 |
CN105106105A (zh) * | 2015-08-14 | 2015-12-02 | 天津市聚星康华医药科技有限公司 | 噻吗洛尔外用制剂治疗婴幼儿血管瘤的应用及其制备方法 |
US20170360829A1 (en) * | 2016-01-27 | 2017-12-21 | Gillies Mcindoe Research Institute | Treatment of vascular anomalies |
RU2617516C1 (ru) * | 2016-03-24 | 2017-04-25 | Государственное бюджетное учреждение здравоохранения города Москвы Научно-исследовательский институт неотложной детской хирургии и травматологии Департамента здравоохранения города Москвы | Способ лечения младенческих гемангиом |
CN106474061B (zh) * | 2016-12-08 | 2019-01-22 | 黑龙江童医生儿童生物制药有限公司 | 一种盐酸普萘洛尔口服乳剂及其制备方法 |
CN108261411B (zh) * | 2016-12-30 | 2021-04-30 | 武汉科福新药有限责任公司 | 用于婴幼儿血管瘤治疗的口腔膜剂及其制备方法 |
EA202090452A1 (ru) | 2017-08-07 | 2020-06-15 | Консехо Супериор Де Инвестигасионес Сьентификас | Соединения для лечения болезни фон гиппеля-линдау |
CN108299279B (zh) * | 2018-02-09 | 2021-03-23 | 北京梅尔森医药技术开发有限公司 | 取代芳基胺醇化合物及其制备方法和用途 |
CN110314154A (zh) * | 2018-03-28 | 2019-10-11 | 武汉恒信源药业有限公司 | 左旋普萘洛尔在制备治疗血管病变药物中的应用 |
US20210346319A1 (en) * | 2018-10-04 | 2021-11-11 | Emory University | Pharmaceutical Compositions of R-(+)-Propranolol in Enantiomeric Excess and Therapeutic Uses Related Thereto |
RU2701213C1 (ru) * | 2018-12-27 | 2019-09-25 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Российский национальный исследовательский медицинский университет имени Н.И. Пирогова" Министерства здравоохранения Российской Федерации (ФГБОУ ВО РНИМУ им. Н.И. Пирогова Минздрава России) | Способ лечения инфантильных гемангиом |
US11154518B2 (en) * | 2018-12-28 | 2021-10-26 | Chang Gung Memorial Hospital, Linkou | Methods and apparatus for treating a wound |
CA3139865A1 (en) * | 2019-05-24 | 2020-12-03 | Pediatric Derm Developement Llc | Treatment of infantile hemangioma |
CN111773226A (zh) * | 2019-06-26 | 2020-10-16 | 首都医科大学附属北京儿童医院 | 噻吗洛尔或其盐在制备预防和/或治疗丛状血管瘤的药物中的用途 |
JP2023512252A (ja) * | 2020-01-29 | 2023-03-24 | ギリーズ マキンドー リサーチ インスティテュート | 血管腫の治療のための方法および組成物 |
JP2023533911A (ja) * | 2020-07-10 | 2023-08-07 | チャン グァン メモリアル ホスピタル,リンコウ | 上皮成長因子受容体阻害剤によって誘発される上皮細胞損傷を軽減し及び癌細胞を阻害する組成物の製造のための、β-1アドレナリン受容体アンタゴニストの使用 |
US20230364242A1 (en) * | 2020-09-30 | 2023-11-16 | Nissan Chemical Corporation | Water-soluble complex containing beta blocker and lecithin |
CN113274348A (zh) * | 2021-06-11 | 2021-08-20 | 四川大学华西医院 | 用于治疗婴幼儿血管瘤的阿替洛尔凝胶、制备方法及应用 |
PL244294B1 (pl) * | 2022-09-20 | 2024-01-03 | Univ Medyczny W Lodzi | Kompozycja farmaceutyczna do stosowania miejscowego oraz jej zastosowanie w leczeniu naczyniaków krwionośnych u dzieci |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL301580A (da) | 1962-12-11 | |||
US3466325A (en) | 1965-04-30 | 1969-09-09 | Haessle Ab | 1-(ortho-alkenyl phenoxy) - 2-hydroxy-3-isopropylaminopropanes and the salts thereof |
GB1253709A (en) | 1968-05-22 | 1971-11-17 | Frosst & Co Charles E | Thiadiazole derivatives |
US3657237A (en) | 1968-05-22 | 1972-04-18 | Frosst & Co Charles E | Process for making 1 2 5-thiadiazoles in the sinister configuration |
US3655663A (en) | 1969-04-21 | 1972-04-11 | Burton K Wasson | 4-(3-secondary amino-2-hydroxy-proxy) 1 2 5-thiadiazoles |
SE354851B (da) | 1970-02-18 | 1973-03-26 | Haessle Ab | |
AT334385B (de) | 1973-12-20 | 1976-01-10 | Chemie Linz Ag | Verfahren zur herstellung von neuen phenoxypropylaminderivaten und deren salzen |
FR2330383A1 (fr) | 1975-11-06 | 1977-06-03 | Synthelabo | Nouveaux ethers de phenols substitues, leurs sels, leur preparation et les medicaments qui les renferment |
US5116867A (en) * | 1989-06-30 | 1992-05-26 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | D-propranolol as a selective adenosine antagonist |
US5182102A (en) * | 1991-07-12 | 1993-01-26 | Alcon Laboratories, Inc. | Anti-glaucoma compositions |
DE69435002T2 (de) * | 1993-07-19 | 2008-03-20 | Angiotech Pharmaceuticals, Inc., Vancouver | Anti-angiogene Mittel enthaltend Taxol und einen nicht biodegradierbaren Träger und deren Verwendung |
US6232299B1 (en) * | 1996-05-01 | 2001-05-15 | Eli Lilly And Company | Use of protein kinase C inhibitors to enhance the clinical efficacy of oncolytic agents and radiation therapy |
IL126837A0 (en) * | 1996-05-01 | 1999-09-22 | Lilly Co Eli | Therapeutic treatment for vegf related diseases |
GB9616672D0 (en) * | 1996-08-08 | 1996-09-25 | Scherer Ltd R P | Pharmaceutical compositions |
US7459470B2 (en) | 2001-05-08 | 2008-12-02 | Schering Ag | N-oxide anthranylamide derivatives and their use as medicaments |
US20050244458A1 (en) * | 2004-04-30 | 2005-11-03 | Allergan, Inc. | Sustained release intraocular implants and methods for treating ocular neuropathies |
CA2576255A1 (en) * | 2004-08-09 | 2006-02-16 | Universite Catholique De Louvain | Use of agonists and antagonists of beta-adrenoceptors for treating arterial diseases |
TW200716141A (en) * | 2005-05-05 | 2007-05-01 | Combinatorx Inc | Compositions and methods for treatment for neoplasms |
EP2050441A1 (en) | 2007-10-19 | 2009-04-22 | Université Victor Segalen Bordeaux 2 | Use of beta blocker for the manufacture of a medicament for the treatment of hemangiomas |
US8987262B2 (en) | 2007-10-19 | 2015-03-24 | Universite de Bordeaux | Use of a beta blocker for the manufacture of a medicament for the treatment of hemangiomas |
-
2007
- 2007-10-19 EP EP07291273A patent/EP2050441A1/en not_active Withdrawn
-
2008
- 2008-10-14 TW TW097139397A patent/TWI531365B/zh active
- 2008-10-16 CN CN2012104556417A patent/CN103169971A/zh active Pending
- 2008-10-16 MY MYPI2010001459A patent/MY156750A/en unknown
- 2008-10-16 AT AT08838691T patent/ATE512661T1/de active
- 2008-10-16 US US12/599,266 patent/US8338489B2/en active Active
- 2008-10-16 DK DK08838691.7T patent/DK2187878T3/da active
- 2008-10-16 EP EP09015563.1A patent/EP2233135B8/en active Active
- 2008-10-16 MX MX2010004295A patent/MX2010004295A/es active IP Right Grant
- 2008-10-16 SI SI200830362T patent/SI2187878T1/sl unknown
- 2008-10-16 PT PT09015563T patent/PT2233135E/pt unknown
- 2008-10-16 CN CN2008801118925A patent/CN102006864B/zh active Active
- 2008-10-16 PL PL08838691T patent/PL2187878T3/pl unknown
- 2008-10-16 KR KR1020107010904A patent/KR101562627B1/ko active IP Right Grant
- 2008-10-16 EP EP08838691A patent/EP2187878B1/en active Active
- 2008-10-16 JP JP2010529467A patent/JP5552700B2/ja active Active
- 2008-10-16 BR BRPI0816536A patent/BRPI0816536A2/pt not_active Application Discontinuation
- 2008-10-16 RU RU2010112816/15A patent/RU2471500C2/ru active
- 2008-10-16 WO PCT/IB2008/002746 patent/WO2009050567A2/en active Application Filing
- 2008-10-16 AU AU2008313405A patent/AU2008313405B2/en active Active
- 2008-10-16 NZ NZ584307A patent/NZ584307A/en unknown
- 2008-10-16 KR KR1020157025385A patent/KR20150110827A/ko not_active Application Discontinuation
- 2008-10-16 PL PL09015563T patent/PL2233135T3/pl unknown
- 2008-10-16 CA CA2701953A patent/CA2701953C/en active Active
- 2008-10-16 PT PT08838691T patent/PT2187878E/pt unknown
- 2008-10-16 DE DE08838691T patent/DE08838691T1/de active Pending
- 2008-10-16 PA PA20088799401A patent/PA8799401A1/es unknown
- 2008-10-16 ES ES09015563T patent/ES2390534T3/es active Active
- 2008-10-16 ES ES08838691T patent/ES2368299T3/es active Active
- 2008-10-16 SI SI200830749T patent/SI2233135T1/sl unknown
- 2008-10-16 DK DK09015563.1T patent/DK2233135T3/da active
- 2008-10-17 CL CL2008003083A patent/CL2008003083A1/es unknown
- 2008-10-17 AR ARP080104555A patent/AR068927A1/es not_active Application Discontinuation
-
2010
- 2010-04-08 CO CO10040510A patent/CO6270209A2/es not_active Application Discontinuation
- 2010-04-15 IL IL205129A patent/IL205129A/en active IP Right Grant
- 2010-04-16 TN TN2010000170A patent/TN2010000170A1/fr unknown
- 2010-05-10 MA MA32829A patent/MA31843B1/fr unknown
- 2010-07-19 HK HK11103063.3A patent/HK1148940A1/xx unknown
-
2011
- 2011-09-07 CY CY20111100858T patent/CY1112604T1/el unknown
- 2011-09-13 HR HR20110659T patent/HRP20110659T1/hr unknown
-
2012
- 2012-09-27 HR HRP20120765AT patent/HRP20120765T1/hr unknown
- 2012-11-16 US US13/678,902 patent/US9173858B2/en active Active
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