PA8543401A1 - Composicion farmaceutica a base de macrolidos para la aplicacion local en oftalmologia - Google Patents
Composicion farmaceutica a base de macrolidos para la aplicacion local en oftalmologiaInfo
- Publication number
- PA8543401A1 PA8543401A1 PA20028543401A PA8543401A PA8543401A1 PA 8543401 A1 PA8543401 A1 PA 8543401A1 PA 20028543401 A PA20028543401 A PA 20028543401A PA 8543401 A PA8543401 A PA 8543401A PA 8543401 A1 PA8543401 A1 PA 8543401A1
- Authority
- PA
- Panama
- Prior art keywords
- macrolides
- composition
- pharmaceutical composition
- vehicle
- local application
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
LA INVENCION SE REFIERE A UNA COMPOSICION FARMACEUTICA PARA LA PREVENCION Y/O EL TRATAMIENTO DE INFECCIONES OCULARES Y QUE SE UTILIZARA EN APLICACION LOCAL. APUNTA EN PARTICULAR A UNA COMPOSICION QUE SE PRESENTA EN LA FORMA DE UN COLIRIO DISTRIBUIBLE GOTA A GOTA EN EL CUAL UN AGENTE ANTIBIOTICO DE LA CLASE DE LOS MACROLIDOS, COMO LA ACITROMICINA, ESTA EN SOLUCION EN UN VEHICULO OLEOSO. ESTE VEHICULO ES PARTICULARMENTE DEL TIPO DE LOS PRODUCTOS ESENCIALMENTE COMPUESTOS DE TRIGLICERIDOS DE CADENA MEDIANA, EN LOS CUALES LAS FUNCIONES ALCOHOL DEL GLICEROL SON ENTERAMENTE ESTERIFICADAS POR ACIDOS CARBOXILICOS DE HIDROCARBUROS SATURADOS, CUYA MOLECULA CONTIENE DE 5 A 12 ATOMOS DE CARBONO. SE TRATA PREFERENTEMENTE DE ACIDOS GRASOS DE CADENA LINEAL QUE CONTIENEN DE 8 A 10 ATOMOS DE CARBONO, COMO EL ACIDO CAPRILICO Y EL ACIDO CAPRICO. LA COMPOSICION ESTA VENTAJOSAMENTE PREPARADA POR UNA PUESTA EN SOLUCION DEL AGENTE ACTIVO EN EL VEHICULO OLEOSO EFECTUADA A UNA TEMPERATURA NO SUPERIOR A LOS 70 ° C.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0105114A FR2823441B1 (fr) | 2001-04-12 | 2001-04-12 | Composition pharmaceutique a base de macrolides pour application locale en ophtalmologie et son procede de preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
PA8543401A1 true PA8543401A1 (es) | 2003-01-24 |
Family
ID=8862340
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PA20028543401A PA8543401A1 (es) | 2001-04-12 | 2002-04-09 | Composicion farmaceutica a base de macrolidos para la aplicacion local en oftalmologia |
Country Status (31)
Country | Link |
---|---|
US (1) | US7064109B2 (es) |
EP (1) | EP1377316B1 (es) |
JP (2) | JP4558275B2 (es) |
KR (1) | KR100835002B1 (es) |
CN (1) | CN1496270B (es) |
AR (1) | AR034033A1 (es) |
AT (1) | ATE397460T1 (es) |
BR (1) | BRPI0208367B8 (es) |
CA (1) | CA2443728C (es) |
CY (1) | CY1108302T1 (es) |
CZ (1) | CZ300213B6 (es) |
DE (1) | DE60226962D1 (es) |
DK (1) | DK1377316T3 (es) |
EA (1) | EA008088B1 (es) |
EG (1) | EG23169A (es) |
ES (1) | ES2307754T3 (es) |
FR (1) | FR2823441B1 (es) |
HK (1) | HK1065708A1 (es) |
HR (1) | HRP20030907B1 (es) |
HU (1) | HU230459B1 (es) |
MA (1) | MA27005A1 (es) |
MX (1) | MXPA03009349A (es) |
OA (1) | OA12462A (es) |
PA (1) | PA8543401A1 (es) |
PE (1) | PE20021082A1 (es) |
PL (1) | PL204403B1 (es) |
PT (1) | PT1377316E (es) |
SI (1) | SI1377316T1 (es) |
TN (1) | TNSN03091A1 (es) |
WO (1) | WO2002083178A1 (es) |
ZA (1) | ZA200307718B (es) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2314354T3 (es) * | 2004-11-09 | 2009-03-16 | Novagali Pharma S.A. | Emulsion de tipo aceite en agua con baja concentracion de agente cationico y potencial zeta positivo. |
FR2884716B1 (fr) * | 2005-04-22 | 2009-08-21 | Thea Sa Lab | Utilisation de l'azithromycine pour la fabrication d'un medicament destine au traitement des infections oculaires |
JPWO2007074904A1 (ja) * | 2005-12-28 | 2009-06-04 | わかもと製薬株式会社 | 水性医薬組成物 |
BRPI0808410A2 (pt) * | 2007-02-28 | 2015-06-23 | Aciex Therapeutics Inc | Métodos e composições para normalizar secreções da glândula meibomiana |
US20100158821A1 (en) * | 2008-12-22 | 2010-06-24 | Eastman Chemical Company | Antimicrobial agents, compositions and products containing the same, and methods of using the compositions and products |
CN101780105B (zh) * | 2009-01-20 | 2011-09-28 | 沈阳兴齐制药有限公司 | 小牛血去蛋白提取物的滴眼液 |
EP2228058A1 (en) | 2009-03-04 | 2010-09-15 | Novagali Pharma S.A. | Anionic oil-in-water emulsion containing prostaglandins and uses thereof |
US8106111B2 (en) * | 2009-05-15 | 2012-01-31 | Eastman Chemical Company | Antimicrobial effect of cycloaliphatic diol antimicrobial agents in coating compositions |
EP2389939A1 (en) | 2010-05-28 | 2011-11-30 | Novagali Pharma S.A. | Use of prostaglandins F2alpha and analogues for the healing of corneal and conjunctival lesions |
EP2394636B1 (en) * | 2010-05-28 | 2014-03-19 | Novagali Pharma S.A. | Method for treating retinal conditions using an intraocular tamponade |
US9044508B2 (en) * | 2013-03-15 | 2015-06-02 | Insite Vision Corporation | Concentrated aqueous azalide formulations |
JP7033789B2 (ja) * | 2016-06-29 | 2022-03-11 | オトノミー,インク. | トリグリセリド耳用製剤とその使用 |
PT3266446T (pt) * | 2016-07-07 | 2019-01-30 | Salvat Lab Sa | Composição oftálmica compreendendo óleo de rícino e triglicérido de cadeia média |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1152644A (en) * | 1966-07-01 | 1969-05-21 | Abbott Lab | Stable Solutions of Erythromycin Free Base |
JPS6468328A (en) * | 1987-09-09 | 1989-03-14 | Suntory Ltd | Anticorneoulcerative |
JP2563336B2 (ja) * | 1987-06-01 | 1996-12-11 | エーザイ株式会社 | 角膜透過促進点眼剤 |
FR2746035B1 (fr) * | 1996-03-15 | 1998-06-12 | Microparticules de gel composite susceptibles d'etre utilisees comme vecteur(s) de principe(s) actif(s), l'un de leurs procedes de preparation et leurs applications | |
PT925789E (pt) * | 1997-12-02 | 2004-10-29 | Pfizer Prod Inc | Es oculares utilizacao de azitromicina no tratamento topico de infecco |
JP2000159659A (ja) * | 1998-11-30 | 2000-06-13 | Kazuo Tsubota | 眼科用人工涙液 |
US6239113B1 (en) * | 1999-03-31 | 2001-05-29 | Insite Vision, Incorporated | Topical treatment or prevention of ocular infections |
-
2001
- 2001-04-12 FR FR0105114A patent/FR2823441B1/fr not_active Expired - Lifetime
-
2002
- 2002-04-09 PA PA20028543401A patent/PA8543401A1/es unknown
- 2002-04-10 EG EG20020380A patent/EG23169A/xx active
- 2002-04-10 AR ARP020101319A patent/AR034033A1/es not_active Application Discontinuation
- 2002-04-11 KR KR1020037012372A patent/KR100835002B1/ko active IP Right Grant
- 2002-04-11 EP EP02732804A patent/EP1377316B1/fr not_active Expired - Lifetime
- 2002-04-11 PT PT02732804T patent/PT1377316E/pt unknown
- 2002-04-11 US US10/474,811 patent/US7064109B2/en not_active Expired - Lifetime
- 2002-04-11 EA EA200301108A patent/EA008088B1/ru not_active IP Right Cessation
- 2002-04-11 OA OA1200300246A patent/OA12462A/fr unknown
- 2002-04-11 PL PL363538A patent/PL204403B1/pl unknown
- 2002-04-11 TN TNPCT/FR2002/001263A patent/TNSN03091A1/fr unknown
- 2002-04-11 SI SI200230723T patent/SI1377316T1/sl unknown
- 2002-04-11 HU HU0303864A patent/HU230459B1/hu unknown
- 2002-04-11 DK DK02732804T patent/DK1377316T3/da active
- 2002-04-11 DE DE60226962T patent/DE60226962D1/de not_active Expired - Lifetime
- 2002-04-11 CA CA2443728A patent/CA2443728C/fr not_active Expired - Lifetime
- 2002-04-11 BR BRPI0208367A patent/BRPI0208367B8/pt not_active IP Right Cessation
- 2002-04-11 ES ES02732804T patent/ES2307754T3/es not_active Expired - Lifetime
- 2002-04-11 MX MXPA03009349A patent/MXPA03009349A/es active IP Right Grant
- 2002-04-11 PE PE2002000306A patent/PE20021082A1/es not_active Application Discontinuation
- 2002-04-11 CN CN02806447XA patent/CN1496270B/zh not_active Expired - Lifetime
- 2002-04-11 JP JP2002580979A patent/JP4558275B2/ja not_active Expired - Lifetime
- 2002-04-11 AT AT02732804T patent/ATE397460T1/de active
- 2002-04-11 WO PCT/FR2002/001263 patent/WO2002083178A1/fr active IP Right Grant
- 2002-04-11 CZ CZ20032771A patent/CZ300213B6/cs not_active IP Right Cessation
-
2003
- 2003-09-26 MA MA27325A patent/MA27005A1/fr unknown
- 2003-10-02 ZA ZA200307718A patent/ZA200307718B/en unknown
- 2003-11-10 HR HR20030907A patent/HRP20030907B1/xx not_active IP Right Cessation
-
2004
- 2004-11-01 HK HK04108553.8A patent/HK1065708A1/xx not_active IP Right Cessation
-
2008
- 2008-08-28 CY CY20081100927T patent/CY1108302T1/el unknown
-
2009
- 2009-10-08 JP JP2009234250A patent/JP5170780B2/ja not_active Expired - Lifetime
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