GT200200275A - Derivados de ester del acido pirrolidina-2-carboxilico - Google Patents
Derivados de ester del acido pirrolidina-2-carboxilicoInfo
- Publication number
- GT200200275A GT200200275A GT200200275A GT200200275A GT200200275A GT 200200275 A GT200200275 A GT 200200275A GT 200200275 A GT200200275 A GT 200200275A GT 200200275 A GT200200275 A GT 200200275A GT 200200275 A GT200200275 A GT 200200275A
- Authority
- GT
- Guatemala
- Prior art keywords
- ester derivatives
- carboxyl acid
- pirrolidine
- treatment
- suero
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
LA PRESENTE INVENCION SE REFIERE A DERIVADOS DE ESTER DEL ACIDO PIRROLIDINA2CARBOXILICO DE FORMULAS GENERALES I Y IA EN DONDE R1,R2,X, SON GRUPOS FUNCIONALES DESCRITOS EN EL EXPEDIENTE. ESTOS COMPUESTOS PUEDEN DESTINARSE AL TRATAMIENTO DE ENFERMEDADES EN LAS QUE LA DEPLECION DEL COMPONENTE P DE AMILOIDE DE SUERO TIENE UN EFECTO BENEFICIOSO, EN ESPECIAL AL TRATAMIENTO O PREVENCION DE TODAS LAS FORMAS DE AMILOIDOSIS CENTRAL O SISTEMICA.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01129793 | 2001-12-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GT200200275A true GT200200275A (es) | 2003-07-30 |
Family
ID=8179542
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GT200200275A GT200200275A (es) | 2001-12-14 | 2002-12-13 | Derivados de ester del acido pirrolidina-2-carboxilico |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US6903129B2 (es) |
| EP (2) | EP1458680A1 (es) |
| JP (1) | JP4192100B2 (es) |
| KR (1) | KR100678785B1 (es) |
| CN (1) | CN100368397C (es) |
| AR (1) | AR038010A1 (es) |
| AU (1) | AU2002361982B2 (es) |
| BR (1) | BR0214932A (es) |
| CA (1) | CA2470037C (es) |
| GT (1) | GT200200275A (es) |
| HK (1) | HK1076100A1 (es) |
| HR (1) | HRP20040494A2 (es) |
| HU (1) | HUP0402600A3 (es) |
| IL (2) | IL162158A0 (es) |
| MX (1) | MXPA04005693A (es) |
| MY (1) | MY129431A (es) |
| NO (1) | NO20042979L (es) |
| NZ (1) | NZ533188A (es) |
| PA (1) | PA8561201A1 (es) |
| PE (1) | PE20030764A1 (es) |
| PL (1) | PL370803A1 (es) |
| RU (1) | RU2305679C2 (es) |
| TW (1) | TWI225400B (es) |
| UY (1) | UY27584A1 (es) |
| WO (1) | WO2003051836A1 (es) |
| ZA (1) | ZA200404546B (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0313386D0 (en) * | 2003-06-10 | 2003-07-16 | Univ London | Treatment of disease |
| UA108227C2 (xx) | 2010-03-03 | 2015-04-10 | Антигензв'язуючий білок | |
| RU2530601C2 (ru) * | 2012-10-05 | 2014-10-10 | Федеральное Государственное Бюджетное Учреждение Науки Институт Молекулярной Биологии Им. В.А. Энгельгардта Российской Академии Наук (Имб Ран) | Ингибитор образования цинк-зависимых димеров бета-амилоида |
| US9737505B2 (en) | 2014-04-29 | 2017-08-22 | Glaxosmithkline Intellectual Property Development Limited | Prodrug of 1,1′-(1,6-dioxo-1,6-hexanediyl)bis-D-proline |
| GB201407506D0 (en) | 2014-04-29 | 2014-06-11 | Glaxosmithkline Ip Dev Ltd | Novel compound |
| GB201518950D0 (en) * | 2015-10-27 | 2015-12-09 | Glaxosmithkline Ip Dev Ltd | Compound |
| WO2017072090A1 (en) * | 2015-10-27 | 2017-05-04 | Glaxosmithkline Intellectual Property Development Limited | Combination therapy |
| GB202111866D0 (en) | 2021-08-18 | 2021-09-29 | Ucl Business Plc | Prodrugs for use in the treatment of tissue damage |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW385308B (en) | 1994-03-04 | 2000-03-21 | Merck & Co Inc | Prodrugs of morpholine tachykinin receptor antagonists |
| ES2182203T3 (es) | 1997-10-31 | 2003-03-01 | Hoffmann La Roche | Derivados de d-prolina. |
-
2002
- 2002-12-02 US US10/307,699 patent/US6903129B2/en not_active Expired - Lifetime
- 2002-12-06 EP EP02796578A patent/EP1458680A1/en not_active Withdrawn
- 2002-12-06 HU HU0402600A patent/HUP0402600A3/hu unknown
- 2002-12-06 AU AU2002361982A patent/AU2002361982B2/en not_active Ceased
- 2002-12-06 MX MXPA04005693A patent/MXPA04005693A/es active IP Right Grant
- 2002-12-06 CA CA2470037A patent/CA2470037C/en not_active Expired - Fee Related
- 2002-12-06 EP EP06020711A patent/EP1743884A1/en not_active Withdrawn
- 2002-12-06 IL IL16215802A patent/IL162158A0/xx unknown
- 2002-12-06 RU RU2004121783/04A patent/RU2305679C2/ru not_active IP Right Cessation
- 2002-12-06 KR KR1020047009036A patent/KR100678785B1/ko not_active IP Right Cessation
- 2002-12-06 WO PCT/EP2002/013827 patent/WO2003051836A1/en not_active Application Discontinuation
- 2002-12-06 JP JP2003552723A patent/JP4192100B2/ja not_active Expired - Fee Related
- 2002-12-06 NZ NZ533188A patent/NZ533188A/en not_active IP Right Cessation
- 2002-12-06 PL PL02370803A patent/PL370803A1/xx not_active Application Discontinuation
- 2002-12-06 CN CNB028249348A patent/CN100368397C/zh not_active Expired - Fee Related
- 2002-12-06 BR BR0214932-0A patent/BR0214932A/pt not_active Application Discontinuation
- 2002-12-10 PE PE2002001184A patent/PE20030764A1/es not_active Application Discontinuation
- 2002-12-11 PA PA20028561201A patent/PA8561201A1/es unknown
- 2002-12-11 TW TW091135829A patent/TWI225400B/zh not_active IP Right Cessation
- 2002-12-12 AR ARP020104818A patent/AR038010A1/es unknown
- 2002-12-13 GT GT200200275A patent/GT200200275A/es unknown
- 2002-12-13 UY UY27584A patent/UY27584A1/es not_active Application Discontinuation
- 2002-12-13 MY MYPI20024679A patent/MY129431A/en unknown
-
2004
- 2004-05-24 IL IL162158A patent/IL162158A/en not_active IP Right Cessation
- 2004-06-01 HR HR20040494A patent/HRP20040494A2/hr not_active Application Discontinuation
- 2004-06-08 ZA ZA200404546A patent/ZA200404546B/en unknown
- 2004-07-13 NO NO20042979A patent/NO20042979L/no not_active Application Discontinuation
-
2005
- 2005-09-16 HK HK05108123A patent/HK1076100A1/xx not_active IP Right Cessation
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