OA12651A - Combination therapy for the treatment of cancer. - Google Patents

Combination therapy for the treatment of cancer. Download PDF

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Publication number
OA12651A
OA12651A OA1200400045A OA1200400045A OA12651A OA 12651 A OA12651 A OA 12651A OA 1200400045 A OA1200400045 A OA 1200400045A OA 1200400045 A OA1200400045 A OA 1200400045A OA 12651 A OA12651 A OA 12651A
Authority
OA
OAPI
Prior art keywords
group
hydrogen
carboxylic acid
alkyl
trifluoromethyl
Prior art date
Application number
OA1200400045A
Other languages
English (en)
Inventor
Julie Cherrington
Jaime Masferrer
Parul Doshi
Original Assignee
Pharmacia Corp
Sugen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Corp, Sugen Inc filed Critical Pharmacia Corp
Publication of OA12651A publication Critical patent/OA12651A/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
OA1200400045A 2001-08-15 2002-08-15 Combination therapy for the treatment of cancer. OA12651A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US31241301P 2001-08-15 2001-08-15

Publications (1)

Publication Number Publication Date
OA12651A true OA12651A (en) 2006-06-15

Family

ID=23211320

Family Applications (1)

Application Number Title Priority Date Filing Date
OA1200400045A OA12651A (en) 2001-08-15 2002-08-15 Combination therapy for the treatment of cancer.

Country Status (36)

Country Link
US (1) US7320996B2 (no)
EP (1) EP1427326B1 (no)
JP (1) JP2005501843A (no)
KR (1) KR100656004B1 (no)
CN (1) CN1541098A (no)
AP (1) AP2004002995A0 (no)
AR (1) AR038957A1 (no)
AT (1) ATE414512T1 (no)
AU (1) AU2002329744B2 (no)
BG (1) BG108622A (no)
BR (1) BR0211978A (no)
CA (1) CA2457745A1 (no)
CO (1) CO5560544A2 (no)
CZ (1) CZ2004356A3 (no)
DE (1) DE60229959D1 (no)
EA (1) EA008137B1 (no)
EC (1) ECSP045021A (no)
GE (1) GEP20063868B (no)
HR (1) HRP20040170A2 (no)
HU (1) HUP0500424A3 (no)
IL (1) IL159887A0 (no)
IS (1) IS7137A (no)
MA (1) MA27060A1 (no)
MX (1) MXPA04001464A (no)
NO (1) NO20040516L (no)
NZ (1) NZ530792A (no)
OA (1) OA12651A (no)
PE (1) PE20030332A1 (no)
PL (1) PL368921A1 (no)
RS (1) RS13204A (no)
SK (1) SK1412004A3 (no)
TN (1) TNSN04015A1 (no)
TW (1) TWI230609B (no)
UA (1) UA77002C2 (no)
WO (1) WO2003015608A2 (no)
ZA (1) ZA200400849B (no)

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US20060009510A1 (en) * 2004-07-09 2006-01-12 Pharmacia & Upjohn Company Llc Method of synthesizing indolinone compounds
CA2603445A1 (en) * 2005-05-12 2006-11-16 Pfizer Inc. Anticancer combination therapy using sunitinib malate
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US20090004213A1 (en) 2007-03-26 2009-01-01 Immatics Biotechnologies Gmbh Combination therapy using active immunotherapy
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EP2181991A1 (en) * 2008-10-28 2010-05-05 LEK Pharmaceuticals D.D. Novel salts of sunitinib
EP2186809A1 (en) * 2008-11-13 2010-05-19 LEK Pharmaceuticals D.D. New crystal form of sunitinib malate
WO2012042421A1 (en) 2010-09-29 2012-04-05 Pfizer Inc. Method of treating abnormal cell growth
RU2495628C1 (ru) * 2012-04-18 2013-10-20 Государственное бюджетное учреждение здравоохранения Московской области "Московский областной научно-исследовательский клинический институт им. М.Ф. Владимирского" (ГБУЗ МО МОНИКИ им. М.Ф. Владимирского) Способ выбора тактики лечения актинического кератоза
TWI646091B (zh) * 2012-12-28 2019-01-01 日商衛斯克慧特股份有限公司 鹽類及晶形
MX2015011456A (es) * 2013-03-13 2016-05-31 Boston Biomedical Inc Derivados de 3-(arilo o heteroailo) metilenindolino-2-ona como inhibidores de cinasas de la via de las celulas madres cancerosas para el tratamiento del cancer.
CN103923014A (zh) * 2014-05-05 2014-07-16 宁夏宝马药业有限公司 环肌酸制备方法
WO2017120591A1 (en) 2016-01-08 2017-07-13 Euclises Pharmaceuticals, Inc. Combination of a chromene compound and a second active agent
CN111759883B (zh) * 2020-07-23 2021-09-17 浙江农林大学 山核桃内果皮提取物在制备抗卵巢癌产品中的应用
CN114853736B (zh) * 2022-07-06 2022-10-21 北京鑫开元医药科技有限公司 具有trk抑制活性的化合物、制备方法、组合物及其用途

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