OA11577A - Non-peptidyl inhibitors of VLA-4 dependent cell vinding useful in treating inflammatory, autoimmune,and respiratory diseases. - Google Patents
Non-peptidyl inhibitors of VLA-4 dependent cell vinding useful in treating inflammatory, autoimmune,and respiratory diseases. Download PDFInfo
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- OA11577A OA11577A OA1200000361A OA1200000361A OA11577A OA 11577 A OA11577 A OA 11577A OA 1200000361 A OA1200000361 A OA 1200000361A OA 1200000361 A OA1200000361 A OA 1200000361A OA 11577 A OA11577 A OA 11577A
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- phenyl
- ureido
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- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Dermatology (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9118098P | 1998-06-30 | 1998-06-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
OA11577A true OA11577A (en) | 2004-07-26 |
Family
ID=22226483
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
OA1200000361A OA11577A (en) | 1998-06-30 | 1999-05-31 | Non-peptidyl inhibitors of VLA-4 dependent cell vinding useful in treating inflammatory, autoimmune,and respiratory diseases. |
Country Status (37)
Country | Link |
---|---|
US (2) | US6355662B1 (xx) |
EP (1) | EP1091943B1 (xx) |
JP (1) | JP3676677B2 (xx) |
KR (1) | KR20010083081A (xx) |
CN (1) | CN1308616A (xx) |
AP (1) | AP1236A (xx) |
AR (1) | AR015312A1 (xx) |
AT (1) | ATE311371T1 (xx) |
AU (1) | AU758939B2 (xx) |
BG (1) | BG105190A (xx) |
BR (1) | BR9911701A (xx) |
CA (1) | CA2336625A1 (xx) |
CO (1) | CO5320599A1 (xx) |
CZ (1) | CZ20004909A3 (xx) |
DE (1) | DE69928667T2 (xx) |
EA (1) | EA004792B1 (xx) |
GT (1) | GT199900101A (xx) |
HN (1) | HN1999000099A (xx) |
HR (1) | HRP20000917A2 (xx) |
HU (1) | HUP0102477A3 (xx) |
ID (1) | ID27414A (xx) |
IL (1) | IL139584A0 (xx) |
IS (1) | IS5720A (xx) |
MA (1) | MA26640A1 (xx) |
NO (1) | NO20006600L (xx) |
NZ (1) | NZ508033A (xx) |
OA (1) | OA11577A (xx) |
PA (1) | PA8477001A1 (xx) |
PE (1) | PE20000762A1 (xx) |
PL (1) | PL345308A1 (xx) |
SK (1) | SK20052000A3 (xx) |
TN (1) | TNSN99110A1 (xx) |
TR (1) | TR200003848T2 (xx) |
UA (1) | UA66864C2 (xx) |
WO (1) | WO2000000477A1 (xx) |
YU (1) | YU77600A (xx) |
ZA (1) | ZA993777B (xx) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6992107B1 (en) | 1995-03-10 | 2006-01-31 | Photocure Asa | Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy |
ATE279396T1 (de) | 1998-06-12 | 2004-10-15 | Sod Conseils Rech Applic | Imidazolderivate und ihre verwendung als somatostatin rezeptorliganden |
CN1308616A (zh) * | 1998-06-30 | 2001-08-15 | 辉瑞产品公司 | 用于治疗炎性、自身免疫和呼吸疾病的依赖于vla-4的细胞结合的非肽基抑制剂 |
US6518292B1 (en) * | 1999-03-12 | 2003-02-11 | Bristol-Myers Squibb Co. | Heterocyclic aromatic compounds usefuls as growth hormone secretagogues |
IL146288A0 (en) * | 1999-06-30 | 2002-07-25 | Daiichi Seiyaku Co | Vla-4 inhibitor compounds |
US6756378B2 (en) * | 1999-06-30 | 2004-06-29 | Pharmacopeia Drug Discovery, Inc. | VLA-4 inhibitor compounds |
KR20020067050A (ko) | 1999-12-28 | 2002-08-21 | 화이자 프로덕츠 인코포레이티드 | 염증성, 자기면역 및 호흡기 질환의 치료에 유용한브이엘에이-4 의존성 세포 결합의 비펩티드계 억제제 |
WO2001056994A1 (en) * | 2000-02-04 | 2001-08-09 | Biogen, Inc. | Integrin antagonists |
AU2001268607A1 (en) * | 2000-06-21 | 2002-01-02 | Bristol-Myers Squibb Company | Piperidine amides as modulators of chemokine receptor activity |
AU2001279098B2 (en) * | 2000-08-01 | 2005-04-14 | Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S | Imidazolyl derivatives |
GB2367816A (en) * | 2000-10-09 | 2002-04-17 | Bayer Ag | Urea- and thiourea-containing derivatives of beta-amino acids |
ATE524441T1 (de) | 2000-12-28 | 2011-09-15 | Daiichi Seiyaku Co | Vla-4-inhibitoren |
DE10111877A1 (de) | 2001-03-10 | 2002-09-12 | Aventis Pharma Gmbh | Neue Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate |
US20030013656A1 (en) * | 2001-05-03 | 2003-01-16 | Bing Wang | Pyruvate derivatives |
MXPA03009660A (es) * | 2001-06-06 | 2004-04-02 | Aventis Pharma Ltd | Tetrahidroisoquinolinas sustituidas para su uso en el tratamiento de enfermedades inflamatorias. |
GB2377933A (en) | 2001-07-06 | 2003-01-29 | Bayer Ag | Succinic acid derivatives useful as integrin antagonists |
DE10137595A1 (de) | 2001-08-01 | 2003-02-13 | Aventis Pharma Gmbh | Neue Imidazolidinderivate, ihre Herstellung und ihre Verwendung |
AU2002326948A1 (en) * | 2001-09-18 | 2003-04-01 | Bristol-Myers Squibb Company | Piperizinones as modulators of chemokine receptor activity |
US7199142B2 (en) | 2002-06-17 | 2007-04-03 | Merck & Co., Inc. | 1-((5-aryl-1,2,4-oxadiazol-3-yl) benzyl)azetidine-3-carboxylates and 1-((5-aryl-1,2,4-oxadiazol-3-yl)benzyl) pyrrolidine-3-carboxylates as edg receptor agonists |
JP4579681B2 (ja) * | 2002-07-09 | 2010-11-10 | ブリストル−マイヤーズ スクイブ カンパニー | 抗糖尿病薬および抗肥満薬として有用な置換ヘテロシクロ誘導体および方法 |
US7691894B2 (en) | 2003-07-24 | 2010-04-06 | Daiichi Pharmaceutical Co., Ltd. | Cyclohexanecarboxylic acid compound |
GB0402812D0 (en) * | 2004-02-09 | 2004-03-10 | Tanabe Seiyaku Co | Novel compounds |
US7309709B2 (en) * | 2004-04-01 | 2007-12-18 | Pfizer Inc. | Thiazole sulfonamide compounds for the treatment of neurodegenerative disorders |
TW200610754A (en) * | 2004-06-14 | 2006-04-01 | Daiichi Seiyaku Co | Vla-4 inhibitor |
US7453002B2 (en) | 2004-06-15 | 2008-11-18 | Bristol-Myers Squibb Company | Five-membered heterocycles useful as serine protease inhibitors |
JP5107724B2 (ja) | 2005-12-13 | 2012-12-26 | 第一三共株式会社 | Vla−4阻害薬 |
US20120258093A1 (en) | 2009-08-20 | 2012-10-11 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Vla-4 as a biomarker for prognosis and target for therapy in duchenne muscular dystrophy |
AU2018311976B2 (en) | 2017-08-04 | 2022-10-13 | Takeda Pharmaceutical Company Limited | Inhibitors of Plasma Kallikrein and uses thereof |
WO2022162164A1 (en) | 2021-01-29 | 2022-08-04 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods of assessing the risk of developing progressive multifocal leukoencephalopathy in patients treated with vla-4 antagonists |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5294713A (en) * | 1991-08-23 | 1994-03-15 | Takeda Chemical Industries, Ltd. | 2-piperazinone compounds and their use |
US6306840B1 (en) * | 1995-01-23 | 2001-10-23 | Biogen, Inc. | Cell adhesion inhibitors |
CN1308616A (zh) * | 1998-06-30 | 2001-08-15 | 辉瑞产品公司 | 用于治疗炎性、自身免疫和呼吸疾病的依赖于vla-4的细胞结合的非肽基抑制剂 |
-
1999
- 1999-05-31 CN CN99808134A patent/CN1308616A/zh active Pending
- 1999-05-31 AU AU38416/99A patent/AU758939B2/en not_active Ceased
- 1999-05-31 BR BR9911701-0A patent/BR9911701A/pt not_active IP Right Cessation
- 1999-05-31 JP JP2000557238A patent/JP3676677B2/ja not_active Expired - Fee Related
- 1999-05-31 NZ NZ508033A patent/NZ508033A/xx unknown
- 1999-05-31 EP EP99921046A patent/EP1091943B1/en not_active Expired - Lifetime
- 1999-05-31 KR KR1020007015120A patent/KR20010083081A/ko active IP Right Grant
- 1999-05-31 CZ CZ20004909A patent/CZ20004909A3/cs unknown
- 1999-05-31 UA UA2000127651A patent/UA66864C2/uk unknown
- 1999-05-31 HU HU0102477A patent/HUP0102477A3/hu unknown
- 1999-05-31 EA EA200001238A patent/EA004792B1/ru not_active IP Right Cessation
- 1999-05-31 IL IL13958499A patent/IL139584A0/xx unknown
- 1999-05-31 AT AT99921046T patent/ATE311371T1/de not_active IP Right Cessation
- 1999-05-31 TR TR2000/03848T patent/TR200003848T2/xx unknown
- 1999-05-31 CA CA002336625A patent/CA2336625A1/en not_active Abandoned
- 1999-05-31 WO PCT/IB1999/000973 patent/WO2000000477A1/en not_active Application Discontinuation
- 1999-05-31 US US09/403,846 patent/US6355662B1/en not_active Expired - Fee Related
- 1999-05-31 OA OA1200000361A patent/OA11577A/en unknown
- 1999-05-31 DE DE69928667T patent/DE69928667T2/de not_active Expired - Fee Related
- 1999-05-31 ID IDW20002723A patent/ID27414A/id unknown
- 1999-05-31 SK SK2005-2000A patent/SK20052000A3/sk unknown
- 1999-05-31 YU YU77600A patent/YU77600A/sh unknown
- 1999-05-31 PL PL99345308A patent/PL345308A1/xx not_active Application Discontinuation
- 1999-06-03 AP APAP/P/1999/001561A patent/AP1236A/en active
- 1999-06-04 ZA ZA9903777A patent/ZA993777B/xx unknown
- 1999-06-07 MA MA25611A patent/MA26640A1/fr unknown
- 1999-06-09 TN TNTNSN99110A patent/TNSN99110A1/fr unknown
- 1999-06-16 AR ARP990102883A patent/AR015312A1/es not_active Application Discontinuation
- 1999-06-17 HN HN1999000099A patent/HN1999000099A/es unknown
- 1999-06-23 US US09/338,832 patent/US6306887B1/en not_active Expired - Fee Related
- 1999-06-25 GT GT199900101A patent/GT199900101A/es unknown
- 1999-06-25 PE PE1999000583A patent/PE20000762A1/es not_active Application Discontinuation
- 1999-06-29 PA PA19998477001A patent/PA8477001A1/es unknown
- 1999-06-30 CO CO99040934A patent/CO5320599A1/es not_active Application Discontinuation
-
2000
- 2000-11-21 IS IS5720A patent/IS5720A/is unknown
- 2000-12-22 NO NO20006600A patent/NO20006600L/no not_active Application Discontinuation
- 2000-12-29 HR HR20000917A patent/HRP20000917A2/hr not_active Application Discontinuation
-
2001
- 2001-01-26 BG BG105190A patent/BG105190A/xx unknown
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