DE69928667D1 - Nicht-peptide inhibitoren von vla-4 abhängiger zellbindung für die behandlung von entzündungen, autoimmune krankheiten und atemstörungen - Google Patents

Nicht-peptide inhibitoren von vla-4 abhängiger zellbindung für die behandlung von entzündungen, autoimmune krankheiten und atemstörungen

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Publication number
DE69928667D1
DE69928667D1 DE69928667T DE69928667T DE69928667D1 DE 69928667 D1 DE69928667 D1 DE 69928667D1 DE 69928667 T DE69928667 T DE 69928667T DE 69928667 T DE69928667 T DE 69928667T DE 69928667 D1 DE69928667 D1 DE 69928667D1
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Prior art keywords
breathtakes
vla
infusion
treatment
cell binding
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Expired - Fee Related
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DE69928667T
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DE69928667T2 (de
Inventor
Jacob Duplantier
John Milici
Stanley Chupak
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Pfizer Products Inc
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Pfizer Products Inc
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DE69928667T 1998-06-30 1999-05-31 Nicht-peptidische Inhibitoren von VLA-4-abhängiger Zellbindung für die Behandlung von entzündlichen, autoimmun-und respiratorischen Krankheiten und Atemstörungen Expired - Fee Related DE69928667T2 (de)

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EP1189612A4 (de) * 1999-06-30 2005-02-16 Daiichi Seiyaku Co Vla-4 hemmende verbindungen
US6756378B2 (en) * 1999-06-30 2004-06-29 Pharmacopeia Drug Discovery, Inc. VLA-4 inhibitor compounds
JP2003519697A (ja) * 1999-12-28 2003-06-24 ファイザー・プロダクツ・インク 炎症性疾患、自己免疫疾患および呼吸器疾患の処置に有用な非ペプチド系のｖｌａ−４依存性細胞結合阻害薬
WO2001056994A1 (en) * 2000-02-04 2001-08-09 Biogen, Inc. Integrin antagonists
EP1296949A2 (de) 2000-06-21 2003-04-02 Bristol-Myers Squibb Pharma Company Piperidinamide zur verwendung als chemokinin-rezeptor-modulatoren
WO2002010140A2 (en) 2000-08-01 2002-02-07 Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) Imidazolyl derivatives
GB2367816A (en) * 2000-10-09 2002-04-17 Bayer Ag Urea- and thiourea-containing derivatives of beta-amino acids
JP4212358B2 (ja) 2000-12-28 2009-01-21 第一三共株式会社 Ｖｌａ−４阻害薬
DE10111877A1 (de) * 2001-03-10 2002-09-12 Aventis Pharma Gmbh Neue Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
CA2446136C (en) * 2001-05-03 2011-07-05 Galileo Pharmaceuticals, Inc. Pyruvate derivatives
DE60224664T2 (de) * 2001-06-06 2009-01-08 Aventis Pharma Ltd., West Malling Substituierte tetrhydroisochinolin-derivate zur behandlung von entzündlichen erkrankungen
GB2377933A (en) 2001-07-06 2003-01-29 Bayer Ag Succinic acid derivatives useful as integrin antagonists
DE10137595A1 (de) 2001-08-01 2003-02-13 Aventis Pharma Gmbh Neue Imidazolidinderivate, ihre Herstellung und ihre Verwendung
WO2003024401A2 (en) * 2001-09-18 2003-03-27 Bristol-Myers Squibb Company Piperizinones as modulators of chemokine receptor activity
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EP1656368A4 (de) * 2002-07-09 2009-08-26 Bristol Myers Squibb Co Als antidiabetika und mittel gegen obesitas geeignete substituierte heterocyclische derivate und verfahren
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US7453002B2 (en) 2004-06-15 2008-11-18 Bristol-Myers Squibb Company Five-membered heterocycles useful as serine protease inhibitors
EP1961750B1 (de) 2005-12-13 2013-09-18 Daiichi Sankyo Company, Limited Vla-4-hemmendes arzneimittel
US20120258093A1 (en) 2009-08-20 2012-10-11 Institut National De La Sante Et De La Recherche Medicale (Inserm) Vla-4 as a biomarker for prognosis and target for therapy in duchenne muscular dystrophy
US11168083B2 (en) 2017-08-04 2021-11-09 Takeda Pharmaceutical Company Limited Inhibitors of Plasma Kallikrein and uses thereof
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KR20010083081A (ko) 2001-08-31
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MA26640A1 (fr) 2004-12-20
WO2000000477A1 (en) 2000-01-06
UA66864C2 (uk) 2004-06-15
BG105190A (en) 2001-12-29
ID27414A (id) 2001-04-05
NO20006600D0 (no) 2000-12-22
SK20052000A3 (sk) 2002-08-06
US6355662B1 (en) 2002-03-12
TR200003848T2 (tr) 2001-06-21
EP1091943A1 (de) 2001-04-18
AU758939B2 (en) 2003-04-03
AP1236A (en) 2004-01-14
NO20006600L (no) 2001-02-21
PA8477001A1 (es) 2000-05-24
AP9901561A0 (en) 1999-06-30
BR9911701A (pt) 2001-03-20
IL139584A0 (en) 2002-02-10
NZ508033A (en) 2002-12-20
TNSN99110A1 (fr) 2005-11-10
EA004792B1 (ru) 2004-08-26
HRP20000917A2 (en) 2002-02-28
EP1091943B1 (de) 2005-11-30
EA200001238A1 (ru) 2001-08-27
AR015312A1 (es) 2001-04-18
DE69928667T2 (de) 2006-08-10
PL345308A1 (en) 2001-12-03
YU77600A (sh) 2004-03-12
US6306887B1 (en) 2001-10-23
AU3841699A (en) 2000-01-17
HUP0102477A2 (hu) 2002-05-29
IS5720A (is) 2000-11-21
HN1999000099A (es) 1999-11-11
OA11577A (en) 2004-07-26
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CA2336625A1 (en) 2000-01-06
ATE311371T1 (de) 2005-12-15
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