OA11049A - Pharmaceutical composition comprising a compound having anti-xa activity and a platelet aggregation antagonist compound - Google Patents
Pharmaceutical composition comprising a compound having anti-xa activity and a platelet aggregation antagonist compound Download PDFInfo
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- OA11049A OA11049A OA9900105A OA9900105A OA11049A OA 11049 A OA11049 A OA 11049A OA 9900105 A OA9900105 A OA 9900105A OA 9900105 A OA9900105 A OA 9900105A OA 11049 A OA11049 A OA 11049A
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- compound
- activity
- platelet
- pharmaceutical composition
- platelet aggregation
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| US3187896P | 1996-11-27 | 1996-11-27 |
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| OA11049A true OA11049A (en) | 2002-02-18 |
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| CN (1) | CN1121224C (cs) |
| AP (1) | AP1390A (cs) |
| AT (1) | ATE283062T1 (cs) |
| AU (1) | AU754936B2 (cs) |
| BG (1) | BG64542B1 (cs) |
| BR (1) | BR9713141A (cs) |
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| IL (1) | IL129877A (cs) |
| NO (1) | NO327740B1 (cs) |
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| PL (1) | PL189116B1 (cs) |
| PT (1) | PT946185E (cs) |
| SI (1) | SI0946185T2 (cs) |
| SK (1) | SK286024B6 (cs) |
| UA (1) | UA63929C2 (cs) |
| WO (1) | WO1998023279A1 (cs) |
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| DK0946185T4 (da) * | 1996-11-27 | 2010-08-30 | Aventis Pharma Inc | Farmaceutisk præparat, som omfatter en forbindelse med anti-Xa-aktivitet og en blodpladeaggregations antagonistforbindelse |
| FR2764511B1 (fr) | 1997-06-13 | 2000-09-08 | Sanofi Sa | Compositions pour le traitement et la prevention de la thrombose arterielle et utilisation d'un inhibiteur du facteur xa seul et/ou en combinaison avec un antiagregant plaquettaire |
| US6136794A (en) * | 1998-02-02 | 2000-10-24 | Merck & Co., Inc. | Platelet aggregation inhibition using low molecular weight heparin in combination with a GP IIb/IIIa antagonist |
| AU1712700A (en) * | 1998-11-18 | 2000-06-05 | G.D. Searle & Co. | Restoration of platelet aggregation by antibody administration after gpiib/iiia antagonist treatment |
| EP1192187A1 (en) * | 1999-06-30 | 2002-04-03 | Hamilton Civic Hospitals Research Development, Inc. | Heparin compositions that inhibit clot associated coagulation factors |
| ES2161615B1 (es) * | 1999-07-23 | 2003-03-16 | Rovi Lab Farmaceut Sa | Composiciones de heparinas de muy bajo peso molecular. |
| US6969705B2 (en) * | 2000-07-21 | 2005-11-29 | Aventis Pharma S.A. | Compositions of polysaccharides derived from heparin, their preparation and pharmaceutical compositions containing them |
| HK1052315A1 (zh) * | 2000-09-08 | 2003-09-11 | Leo Pharma A/S | 抗血栓形成合成物 |
| US6982251B2 (en) * | 2000-12-20 | 2006-01-03 | Schering Corporation | Substituted 2-azetidinones useful as hypocholesterolemic agents |
| DK1413331T3 (da) | 2001-01-26 | 2007-12-10 | Schering Corp | Kombinationer af peroxisomproliferatoraktiveret receptor (PPAR)-aktivatoren fenofibrat og sterolabsorptionsinhibitoren ezetimib til vaskulære indikationer |
| IL156422A0 (en) | 2001-01-26 | 2004-01-04 | Schering Corp | The use of substituted azetidinone compounds for the treatment of sitosterolemia |
| US7071181B2 (en) | 2001-01-26 | 2006-07-04 | Schering Corporation | Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors |
| DE10141106A1 (de) * | 2001-08-22 | 2003-03-13 | Aventis Pharma Gmbh | Verwendung von Heparinoid-Derivaten zur Behandlung und Diagnose von mit Heparinoiden behandelbaren Erkrankungen |
| US7053080B2 (en) | 2001-09-21 | 2006-05-30 | Schering Corporation | Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors |
| ATE345793T1 (de) | 2001-09-21 | 2006-12-15 | Schering Corp | Behandlung von xanthom mittels azetidinon- derivate als hemmer der sterol absorption |
| US20040171819A1 (en) * | 2002-10-10 | 2004-09-02 | Aventis Pharma S.A. | Mixtures of polysaccharides derived from heparin, their preparation and pharmaceutical compositions containing them |
| EP1560579A1 (en) | 2002-11-06 | 2005-08-10 | Schering Corporation | Cholesterol absorption inhibitors for the treatment of autoimmune disorders |
| CA2517571C (en) * | 2003-03-07 | 2011-07-05 | Schering Corporation | Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof |
| CA2517573C (en) | 2003-03-07 | 2011-12-06 | Schering Corporation | Substituted azetidinone compounds, formulations and uses thereof for the treatment of hypercholesterolemia |
| US7208486B2 (en) | 2003-03-07 | 2007-04-24 | Schering Corporation | Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof |
| US7459442B2 (en) | 2003-03-07 | 2008-12-02 | Schering Corporation | Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof |
| US7956046B2 (en) * | 2003-07-24 | 2011-06-07 | Aventis Pharma S.A. | Oligosaccharide mixtures derived from heparin, preparation thereof and pharmaceutical compositions containing them |
| EP1537871A1 (en) * | 2003-12-04 | 2005-06-08 | Aventis Pharma S.A. | Enoxaparin for the treatment of cancer |
| TWI396686B (zh) | 2004-05-21 | 2013-05-21 | Takeda Pharmaceutical | 環狀醯胺衍生物、以及其製品和用法 |
| KR100601429B1 (ko) * | 2004-07-09 | 2006-07-14 | 주식회사 대우일렉트로닉스 | 기계식 전자렌지의 댐퍼 구동회로 |
| AR067345A1 (es) * | 2007-07-10 | 2009-10-07 | Paion Deutschland Gmbh | Uso de trombomodulina para la preparacion de un medicamento trombolitico |
| EP2014296A1 (en) * | 2007-07-10 | 2009-01-14 | PAION Deutschland GmbH | Novel strategies for increasing the reperfusion in obstructed blood vessel |
| CN101783857B (zh) * | 2009-05-12 | 2011-11-30 | 上海海事大学 | 一种基于fpga在高分辨率成像系统中的图像矩阵化预处理方法 |
| IT1400232B1 (it) * | 2010-05-07 | 2013-05-24 | Advance Holdings Ltd | Composizione farmaceutica topica comprendente eparina |
| WO2011149110A1 (en) | 2010-05-28 | 2011-12-01 | Daiichi Sankyo Company, Limited | Novel composition for the prevention and/or treatment of thromboembolism |
| EP2508892A1 (de) * | 2011-04-04 | 2012-10-10 | Siemens Healthcare Diagnostics Products GmbH | Kontrollen und Kit für Thrombozytenaktivitätsteste |
| RU2554803C1 (ru) * | 2014-06-26 | 2015-06-27 | Федеральное государственное бюджетное учреждение "Ростовский научно-исследовательский онкологический институт" Министерства здравоохранения Российской Федерации | Способ профилактики развития послеоперационных венозных тромбоэмболических осложнений у пациентов с колоректальным раком |
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| US3766167A (en) * | 1971-03-26 | 1973-10-16 | Research Corp | Orally active anticoagulant |
| FR2478646A2 (fr) * | 1980-03-20 | 1981-09-25 | Choay Sa | Composition mucopolysaccharidique ayant une activite regulatrice de la coagulation, medicament la contenant et procede pour l'obtenir |
| US4692435A (en) * | 1978-11-06 | 1987-09-08 | Choay, S.A. | Mucopolysaccharide composition having a regulatory action on coagulation, medicament containing same and process of preparation |
| SE449753B (sv) * | 1978-11-06 | 1987-05-18 | Choay Sa | Mukopolysackaridkomposition med reglerande verkan pa koagulation, lekemedel innehallande densamma samt forfarande for framstellning derav |
| FR2440376A1 (fr) * | 1978-11-06 | 1980-05-30 | Choay Sa | Composition mucopolysaccharidique ayant une activite regulatrice de la coagulation, medicament la contenant et procede pour l'obtenir |
| CA1136620A (en) * | 1979-01-08 | 1982-11-30 | Ulf P.F. Lindahl | Heparin fragments having selective anticoagulation activity |
| US4826827A (en) * | 1979-10-05 | 1989-05-02 | Choay S.A. | Short chained oligosaccharides having biological properties, a process for making the same and the use thereof as drugs |
| FR2482611B1 (fr) * | 1980-05-14 | 1986-03-07 | Pharmindustrie | Nouveaux polysaccharides sulfates, procedes pour leur preparation et leur utilisation comme medicaments |
| US4351938A (en) * | 1980-05-19 | 1982-09-28 | Riker Laboratories, Inc. | Anticoagulant substance |
| FR2503714B1 (fr) * | 1981-04-10 | 1986-11-21 | Choay Sa | Procede d'obtention de mucopolysaccharides biologiquement actifs, de purete elevee, par depolymerisation de l'heparine |
| DE3265781D1 (en) * | 1981-05-21 | 1985-10-03 | Akzo Nv | New anti-thromboticum based on polysacharides, method for its preparation and pharmaceutical compositions |
| US4533549A (en) * | 1983-01-04 | 1985-08-06 | Lasker Sigmund E | Antithrombotic agent |
| IT1195497B (it) * | 1983-03-08 | 1988-10-19 | Opocrin Spa | Procedimento per la preparazione di frazioni oligosaccaridiche dotate di proprieta' farmacologiche per degradazione chimica di eparina |
| US4683291A (en) * | 1985-10-28 | 1987-07-28 | Scripps Clinic And Research Foundation | Platelet binding inhibitors |
| DK196986D0 (da) * | 1986-04-30 | 1986-04-30 | Novo Industri As | Fremstilling af polysaccharider |
| DK196886D0 (da) * | 1986-04-30 | 1986-04-30 | Novo Industri As | Fremstilling af polysaccharider |
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-
1997
- 1997-11-24 DK DK97948482.1T patent/DK0946185T4/da active
- 1997-11-24 PT PT97948482T patent/PT946185E/pt unknown
- 1997-11-24 UA UA99063586A patent/UA63929C2/uk unknown
- 1997-11-24 AU AU54546/98A patent/AU754936B2/en not_active Ceased
- 1997-11-24 CN CN97180019A patent/CN1121224C/zh not_active Expired - Fee Related
- 1997-11-24 WO PCT/US1997/021440 patent/WO1998023279A1/en active IP Right Grant
- 1997-11-24 BR BR9713141-5A patent/BR9713141A/pt not_active Application Discontinuation
- 1997-11-24 AP APAP/P/1999/001517A patent/AP1390A/en active
- 1997-11-24 CA CA002272317A patent/CA2272317C/en not_active Expired - Fee Related
- 1997-11-24 CZ CZ0174299A patent/CZ298552B6/cs not_active IP Right Cessation
- 1997-11-24 AT AT97948482T patent/ATE283062T1/de active
- 1997-11-24 PL PL97333665A patent/PL189116B1/pl not_active IP Right Cessation
- 1997-11-24 DE DE69731763T patent/DE69731763T3/de not_active Expired - Lifetime
- 1997-11-24 SI SI9730691T patent/SI0946185T2/sl unknown
- 1997-11-24 ES ES97948482T patent/ES2230624T5/es not_active Expired - Lifetime
- 1997-11-24 IL IL12987797A patent/IL129877A/en not_active IP Right Cessation
- 1997-11-24 EA EA199900499A patent/EA002475B1/ru not_active IP Right Cessation
- 1997-11-24 JP JP52478398A patent/JP4498471B2/ja not_active Expired - Fee Related
- 1997-11-24 EP EP97948482A patent/EP0946185B2/en not_active Expired - Lifetime
- 1997-11-24 HU HU9903496A patent/HUP9903496A3/hu unknown
- 1997-11-24 SK SK673-99A patent/SK286024B6/sk not_active IP Right Cessation
- 1997-11-24 KR KR10-1999-7004656A patent/KR100512671B1/ko not_active Expired - Fee Related
- 1997-11-27 ZA ZA9710691A patent/ZA9710691B/xx unknown
-
1998
- 1998-11-16 US US09/192,710 patent/US6103705A/en not_active Expired - Lifetime
-
1999
- 1999-04-29 BG BG103372A patent/BG64542B1/bg unknown
- 1999-05-19 OA OA9900105A patent/OA11049A/en unknown
- 1999-05-27 NO NO19992555A patent/NO327740B1/no not_active IP Right Cessation
-
2000
- 2000-03-01 US US09/516,981 patent/US20020032214A1/en not_active Abandoned
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