OA10325A - Crystalline N-acetyl neuraminic acid derivatives and processes for their preparation - Google Patents

Crystalline N-acetyl neuraminic acid derivatives and processes for their preparation Download PDF

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Publication number
OA10325A
OA10325A OA60842A OA60842A OA10325A OA 10325 A OA10325 A OA 10325A OA 60842 A OA60842 A OA 60842A OA 60842 A OA60842 A OA 60842A OA 10325 A OA10325 A OA 10325A
Authority
OA
OAPI
Prior art keywords
crystalline form
hydrate
tetradeoxy
acetamido
glycero
Prior art date
Application number
OA60842A
Other languages
English (en)
French (fr)
Inventor
Christopher Williamson
William James White
Vipulkumar Patel
Original Assignee
Biota Scient Management
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biota Scient Management filed Critical Biota Scient Management
Publication of OA10325A publication Critical patent/OA10325A/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Oncology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
OA60842A 1993-12-17 1996-06-14 Crystalline N-acetyl neuraminic acid derivatives and processes for their preparation OA10325A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB939325841A GB9325841D0 (en) 1993-12-17 1993-12-17 Chemical compounds

Publications (1)

Publication Number Publication Date
OA10325A true OA10325A (en) 1997-10-07

Family

ID=10746778

Family Applications (2)

Application Number Title Priority Date Filing Date
OA60842A OA10325A (en) 1993-12-17 1996-06-14 Crystalline N-acetyl neuraminic acid derivatives and processes for their preparation
OA1200000004A OA11275A (en) 1993-12-17 2000-01-06 Crystalline n-acetyl neuraminic acid derivatives and processes for their preparation.

Family Applications After (1)

Application Number Title Priority Date Filing Date
OA1200000004A OA11275A (en) 1993-12-17 2000-01-06 Crystalline n-acetyl neuraminic acid derivatives and processes for their preparation.

Country Status (44)

Country Link
US (2) US6294572B1 (da)
EP (1) EP0734382B1 (da)
JP (1) JP3317972B2 (da)
KR (1) KR100403256B1 (da)
CN (2) CN1132829C (da)
AP (2) AP9600810A0 (da)
AT (1) ATE199255T1 (da)
BG (1) BG63338B1 (da)
BR (2) BR9408340A (da)
CA (1) CA2177990C (da)
CO (1) CO4340619A1 (da)
CZ (1) CZ289234B6 (da)
DE (1) DE69426726T2 (da)
DK (1) DK0734382T3 (da)
EE (1) EE03353B1 (da)
EG (1) EG20597A (da)
ES (1) ES2155517T3 (da)
FI (1) FI120453B (da)
GB (1) GB9325841D0 (da)
GR (1) GR3035681T3 (da)
HK (1) HK1014187A1 (da)
HR (1) HRP941001B1 (da)
HU (1) HU221971B1 (da)
IL (1) IL112011A (da)
IS (1) IS4240A (da)
MA (1) MA23396A1 (da)
MY (1) MY116221A (da)
NO (1) NO314759B1 (da)
NZ (1) NZ277789A (da)
OA (2) OA10325A (da)
PE (1) PE31095A1 (da)
PL (1) PL186384B1 (da)
PT (1) PT734382E (da)
RO (1) RO114792B1 (da)
RU (1) RU2134690C1 (da)
SA (1) SA94150417B1 (da)
SG (1) SG46669A1 (da)
SI (1) SI0734382T1 (da)
SK (1) SK282972B6 (da)
SV (1) SV1994000076A (da)
TW (1) TW452577B (da)
UA (1) UA46723C2 (da)
WO (1) WO1995016680A1 (da)
ZA (1) ZA9410003B (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9325841D0 (en) * 1993-12-17 1994-02-23 Glaxo Group Ltd Chemical compounds
WO1996026933A1 (en) 1995-02-27 1996-09-06 Gilead Sciences, Inc. Novel selective inhibitors of viral or bacterial neuraminidases
US5866601A (en) * 1995-02-27 1999-02-02 Gilead Sciences, Inc. Carbocyclic compounds
US5763483A (en) * 1995-12-29 1998-06-09 Gilead Sciences, Inc. Carbocyclic compounds
US6340702B1 (en) 1996-07-22 2002-01-22 Sankyo Company, Limited Neuraminic acid derivatives, their preparation and their medical use
US6451766B1 (en) 1996-07-22 2002-09-17 Sankyo Company, Limited Neuraminic acid derivatives, their preparation and their medical use
PT823428E (pt) * 1996-07-22 2002-04-29 Sankyo Co Derivados do acido neuraminico sua preparacao e sua utilizacao em medicina
US5859284A (en) * 1996-08-23 1999-01-12 Gilead Sciences, Inc. Preparation of carbocyclic compounds
US6518438B2 (en) 1996-08-23 2003-02-11 Gilead Sciences, Inc. Preparation of cyclohexene carboxylate derivatives
US5994377A (en) 1996-10-21 1999-11-30 Gilead Sciences, Inc. Piperidine compounds
US5886213A (en) * 1997-08-22 1999-03-23 Gilead Sciences, Inc. Preparation of carbocyclic compounds
TW477783B (en) * 1997-12-12 2002-03-01 Gilead Sciences Inc Novel compounds useful as neuraminidase inhibitors and pharmaceutical compositions containing same
TWI291462B (en) 2000-04-25 2007-12-21 Daiichi Sankyo Co Ltd Hydrate crystal of neuraminic acid compound
US20080063722A1 (en) * 2006-09-08 2008-03-13 Advanced Inhalation Research, Inc. Composition of a Spray-Dried Powder for Pulmonary Delivery of a Long Acting Neuraminidase Inhibitor (LANI)
BR112014014635A2 (pt) * 2011-12-16 2017-06-13 Daiichi Sankyo Co Ltd método para fabricar um composto, e, composto
CN109232677B (zh) * 2018-10-18 2021-12-28 中国科学院合肥物质科学研究院 一种使n-乙酰神经氨酸水合物转化为n-乙酰神经氨酸的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK282950B6 (sk) * 1990-04-24 2003-01-09 Biota Scientific Management Pty Ltd Deriváty alfa-D-neuramínovej kyseliny, spôsob ich prípravy, ich použitie a farmaceutické prípravky na ich báze
CA2081068C (en) * 1991-10-23 2005-11-29 Laurence Mark Von Itzstein Antiviral 4-substituted-2-deoxy-2,3-didehydro-derivatives of .alpha.-d-neuraminic acid
US5639786A (en) 1992-12-04 1997-06-17 Biota Scientific Management, Pty., Ltd. Antiviral 4-substituted-2-deoxy-2,3-didehydro-derivatives of α-D-neuraninic acid
GB9325841D0 (en) * 1993-12-17 1994-02-23 Glaxo Group Ltd Chemical compounds

Also Published As

Publication number Publication date
CA2177990A1 (en) 1995-06-22
PL186384B1 (pl) 2004-01-30
SV1994000076A (es) 1995-10-26
NO962545L (no) 1996-06-14
BG100709A (bg) 1997-01-31
SK78596A3 (en) 1997-03-05
HRP941001A2 (en) 1997-06-30
KR100403256B1 (ko) 2004-04-30
SA94150417B1 (ar) 2005-12-18
SG46669A1 (en) 1998-02-20
PL315055A1 (en) 1996-09-30
BR1100548KB1 (pt) 2011-11-01
JP3317972B2 (ja) 2002-08-26
DE69426726T2 (de) 2001-06-21
SK282972B6 (sk) 2003-01-09
US20020037865A1 (en) 2002-03-28
DE69426726D1 (de) 2001-03-29
OA11275A (en) 2002-11-20
TW452577B (en) 2001-09-01
IL112011A (en) 1998-08-16
PT734382E (pt) 2001-06-29
AP9400705A0 (en) 1995-01-31
ATE199255T1 (de) 2001-03-15
AU689185B2 (en) 1998-03-26
RO114792B1 (ro) 1999-07-30
HK1014187A1 (en) 1999-09-24
CN1502621A (zh) 2004-06-09
CZ289234B6 (cs) 2001-12-12
IS4240A (is) 1995-06-18
HU221971B1 (hu) 2003-03-28
PE31095A1 (es) 1995-10-18
AP541A (en) 1996-10-01
EP0734382A1 (en) 1996-10-02
EP0734382B1 (en) 2001-02-21
ES2155517T3 (es) 2001-05-16
HU9601642D0 (en) 1996-08-28
DK0734382T3 (da) 2001-03-19
JPH09506601A (ja) 1997-06-30
FI962464A (fi) 1996-06-13
CZ169396A3 (en) 1996-11-13
HRP941001B1 (en) 2001-06-30
CO4340619A1 (es) 1996-07-30
CN1132829C (zh) 2003-12-31
WO1995016680A1 (en) 1995-06-22
IL112011A0 (en) 1995-03-15
CA2177990C (en) 2000-04-25
UA46723C2 (uk) 2002-06-17
NZ277789A (en) 1999-04-29
MY116221A (en) 2003-12-31
HUT74938A (en) 1997-03-28
AU1314495A (en) 1995-07-03
BR9408340A (pt) 1997-08-19
EG20597A (en) 1999-09-30
NO962545D0 (no) 1996-06-14
MA23396A1 (fr) 1995-07-01
AP9600810A0 (en) 1996-07-31
BG63338B1 (bg) 2001-10-31
FI962464A0 (fi) 1996-06-13
GR3035681T3 (en) 2001-06-29
GB9325841D0 (en) 1994-02-23
CN1142820A (zh) 1997-02-12
FI120453B (fi) 2009-10-30
SI0734382T1 (en) 2001-08-31
EE03353B1 (et) 2001-02-15
ZA9410003B (en) 1995-07-25
US6294572B1 (en) 2001-09-25
RU2134690C1 (ru) 1999-08-20
NO314759B1 (no) 2003-05-19

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