NZ623574A - Ketolide compounds - Google Patents
Ketolide compoundsInfo
- Publication number
- NZ623574A NZ623574A NZ623574A NZ62357411A NZ623574A NZ 623574 A NZ623574 A NZ 623574A NZ 623574 A NZ623574 A NZ 623574A NZ 62357411 A NZ62357411 A NZ 62357411A NZ 623574 A NZ623574 A NZ 623574A
- Authority
- NZ
- New Zealand
- Prior art keywords
- compounds
- formula
- carboxamidino
- decladinosyl
- thiadiazol
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 5
- 239000003835 ketolide antibiotic agent Substances 0.000 title abstract 2
- 229960003276 erythromycin Drugs 0.000 abstract 2
- 125000001072 heteroaryl group Chemical group 0.000 abstract 2
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 2
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical group FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000000845 anti-microbial effect Effects 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- CREMABGTGYGIQB-UHFFFAOYSA-N carbon carbon Chemical compound C.C CREMABGTGYGIQB-UHFFFAOYSA-N 0.000 abstract 1
- 239000011203 carbon fibre reinforced carbon Substances 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 229910052731 fluorine Chemical group 0.000 abstract 1
- 239000011737 fluorine Chemical group 0.000 abstract 1
- 150000004677 hydrates Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 230000000813 microbial effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- 125000003107 substituted aryl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H23/00—Compounds containing boron, silicon or a metal, e.g. chelates or vitamin B12
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN3352MU2010 | 2010-12-09 | ||
| NZ611653A NZ611653B (en) | 2010-12-09 | 2011-02-03 | Ketolide compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ623574A true NZ623574A (en) | 2015-07-31 |
Family
ID=54259620
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ623574A NZ623574A (en) | 2010-12-09 | 2011-02-03 | Ketolide compounds |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US9175031B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP2673285B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP5851516B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR101657751B1 (cg-RX-API-DMAC7.html) |
| CN (2) | CN103384676B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2011340204B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112013014392B1 (cg-RX-API-DMAC7.html) |
| CA (2) | CA2820451C (cg-RX-API-DMAC7.html) |
| DK (1) | DK2673285T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2642287T3 (cg-RX-API-DMAC7.html) |
| HU (1) | HUE036658T2 (cg-RX-API-DMAC7.html) |
| MX (1) | MX348084B (cg-RX-API-DMAC7.html) |
| NZ (1) | NZ623574A (cg-RX-API-DMAC7.html) |
| PL (1) | PL2673285T3 (cg-RX-API-DMAC7.html) |
| PT (1) | PT2673285T (cg-RX-API-DMAC7.html) |
| RU (1) | RU2601550C2 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2012076989A1 (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA201304150B (cg-RX-API-DMAC7.html) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ587490A (en) * | 2010-08-20 | 2013-03-28 | Greentide Ltd | Anti-Microbial Compounds containing compounds with a sugar substituent |
| WO2012127351A1 (en) * | 2011-03-22 | 2012-09-27 | Wockhardt Limited | Process for preparation of ketolide compounds |
| US9346828B2 (en) * | 2013-06-07 | 2016-05-24 | Wisconsin Alumni Research Foundation | Forazolines, compositions thereof and uses thereof |
| KR101799009B1 (ko) * | 2015-07-27 | 2017-11-17 | 주식회사 종근당 | 히스톤 탈아세틸화효소 6 억제제로서의 1,3,4-옥사다이아졸 아마이드 유도체 화합물 및 이를 포함하는 약제학적 조성물 |
| RU2697665C1 (ru) | 2015-07-27 | 2019-08-16 | Чонг Кун Данг Фармасьютикал Корп. | Производные 1,3,4-оксадиазолсульфонамида в качестве ингибиторов деацетилазы гистонов 6 и фармацевтическая композиция, содержащая их |
| MY194018A (en) | 2015-07-27 | 2022-11-08 | Chong Kun Dang Pharmaceutical Corp | 1,3,4-oxadiazole sulfamide derivative compounds as histone deacetylase 6 inhibitor, and the pharmaceutical composition comprising the same |
| EP3331864B1 (en) | 2015-08-04 | 2021-11-03 | Chong Kun Dang Pharmaceutical Corp. | 1,3,4-oxadiazole derivative compounds as histone deacetylase 6 inhibitor, and the pharmaceutical composition comprising the same |
| AU2016338118B2 (en) | 2015-10-12 | 2019-03-14 | Chong Kun Dang Pharmaceutical Corp. | Oxadiazole amine derivative compounds as histone deacetylase 6 inhibitor, and the pharmaceutical composition comprising the same |
| AU2017206671A1 (en) * | 2016-01-12 | 2018-08-23 | Wockhardt Limited | Pharmaceutical compositions for the treatment of bacterial infections |
| WO2017122127A1 (en) * | 2016-01-12 | 2017-07-20 | Wockhardt Limited | Pharmaceutical compositions |
| US10857171B2 (en) * | 2016-01-12 | 2020-12-08 | Wockhardt Limited | Pharmaceutical compositions |
| JP6887022B2 (ja) * | 2017-03-16 | 2021-06-16 | ウォックハート リミテッド | ケトライド化合物を製造するための方法 |
| KR102316234B1 (ko) | 2018-07-26 | 2021-10-22 | 주식회사 종근당 | 히스톤 탈아세틸화효소 6 억제제로서의 1,3,4-옥사다이아졸 유도체 화합물 및 이를 포함하는 약제학적 조성물 |
| JP7451569B2 (ja) | 2019-05-31 | 2024-03-18 | チョン クン ダン ファーマシューティカル コーポレーション | ヒストン脱アセチル化酵素６阻害剤としての１，３，４－オキサジアゾールホモフタルイミド誘導体化合物、およびそれを含む薬剤学的組成物 |
| JP7712922B2 (ja) | 2019-11-05 | 2025-07-24 | デルミラ インコーポレイテッド | 炎症性障害を治療するためのＭｒｇｐｒＸ２アンタゴニスト |
| US20230002336A1 (en) * | 2019-11-05 | 2023-01-05 | Dermira, Inc. | MrgprX2 Antagonists and Uses Thereof |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2473525A1 (fr) | 1980-01-11 | 1981-07-17 | Roussel Uclaf | Nouvelles oximes derivees de l'erythromycine, leur procede de preparation et leur application comme medicaments |
| US4331803A (en) | 1980-06-04 | 1982-05-25 | Taisho Pharmaceutical Co., Ltd. | Novel erythromycin compounds |
| YU43006B (en) | 1981-03-06 | 1989-02-28 | Pliva Pharm & Chem Works | Process for preparing n-methyl-11-aza-10-deoxo-10-dihydro erythromycin and derivatives thereof |
| FR2719587B1 (fr) | 1994-05-03 | 1996-07-12 | Roussel Uclaf | Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments. |
| DK1291351T3 (da) | 1996-09-04 | 2005-10-24 | Abbott Lab | 6-O-substituerede ketolider med antibakteriel aktivitet |
| WO1999021870A1 (en) * | 1997-10-29 | 1999-05-06 | Taisho Pharmaceutical Co., Ltd. | Erythromycin a 11, 12-carbamate derivatives |
| HRP980189B1 (en) * | 1998-04-06 | 2004-04-30 | Pliva Pharm & Chem Works | Novel 15-membered lactams ketolides |
| FR2777282B1 (fr) * | 1998-04-08 | 2001-04-20 | Hoechst Marion Roussel Inc | Nouveaux derives de la 2-fluoro 3-de((2,6-dideoxy 3-c-methyl 3-0-methyl-alpha-l-ribohexopyranosyl) oxyl) 6-o-methyl 3-oxo erythromycine, leur procede de preparation et leur application a la synthese de principes actifs de medicaments |
| KR100502031B1 (ko) | 2000-08-22 | 2005-07-25 | 바실리어 파마슈티카 아게 | 항균 활성을 갖는 신규한 매크롤라이드 |
| GB0031312D0 (en) | 2000-12-21 | 2001-02-07 | Glaxo Group Ltd | Macrolides |
| CN1492874A (zh) | 2000-12-21 | 2004-04-28 | 大环内酯 | |
| GB0127349D0 (en) | 2001-11-14 | 2002-01-02 | Glaxo Group Ltd | Macrolides |
| US6995143B2 (en) * | 2002-02-28 | 2006-02-07 | Basilea Pharmaceutica Ag | Macrolides with antibacterial activity |
| US6727229B2 (en) | 2002-08-19 | 2004-04-27 | Enanta Pharmaceuticals, Inc. | 11,12-substituted lactone ketolide derivatives having antibacterial activity |
| WO2004108744A2 (en) * | 2003-05-19 | 2004-12-16 | Prasad K Deshpande | Azalides and azaketolides having antimicrobial activity |
| JP2008508322A (ja) * | 2004-07-28 | 2008-03-21 | ランバクシー ラボラトリーズ リミテッド | 抗菌剤としてのケトライド誘導体 |
| CN101541331A (zh) * | 2006-08-24 | 2009-09-23 | 沃克哈特研究中心 | 具有抗微生物活性的新颖大环内酯和酮内酯 |
| US20090075915A1 (en) * | 2007-09-17 | 2009-03-19 | In Jong Kim | 6,11-bicyclolides: bridged biaryl macrolide derivatives |
| US8552162B2 (en) * | 2008-05-09 | 2013-10-08 | Enanta Pharmaceuticals, Inc. | Processes for the preparation of 2 fluoro 6-11 bicyclic erythromycin derivatives |
| EP2435460B1 (en) * | 2009-05-27 | 2015-01-07 | Wockhardt Limited | Ketolide compounds having antimicrobial activity |
-
2011
- 2011-02-03 CN CN201180066627.1A patent/CN103384676B/zh active Active
- 2011-02-03 US US13/991,762 patent/US9175031B2/en active Active
- 2011-02-03 AU AU2011340204A patent/AU2011340204B2/en not_active Ceased
- 2011-02-03 EP EP11708092.9A patent/EP2673285B1/en active Active
- 2011-02-03 HU HUE11708092A patent/HUE036658T2/hu unknown
- 2011-02-03 EP EP17164547.6A patent/EP3216798A3/en not_active Withdrawn
- 2011-02-03 CN CN201610004950.0A patent/CN105669803A/zh active Pending
- 2011-02-03 RU RU2013131234/04A patent/RU2601550C2/ru active
- 2011-02-03 MX MX2013006461A patent/MX348084B/es active IP Right Grant
- 2011-02-03 NZ NZ623574A patent/NZ623574A/en not_active IP Right Cessation
- 2011-02-03 JP JP2013542630A patent/JP5851516B2/ja not_active Expired - Fee Related
- 2011-02-03 ES ES11708092.9T patent/ES2642287T3/es active Active
- 2011-02-03 BR BR112013014392-4A patent/BR112013014392B1/pt active IP Right Grant
- 2011-02-03 CA CA2820451A patent/CA2820451C/en not_active Expired - Fee Related
- 2011-02-03 WO PCT/IB2011/050464 patent/WO2012076989A1/en not_active Ceased
- 2011-02-03 PL PL11708092T patent/PL2673285T3/pl unknown
- 2011-02-03 KR KR1020137016527A patent/KR101657751B1/ko not_active Expired - Fee Related
- 2011-02-03 CA CA2964104A patent/CA2964104A1/en not_active Abandoned
- 2011-02-03 PT PT117080929T patent/PT2673285T/pt unknown
- 2011-02-03 DK DK11708092.9T patent/DK2673285T3/en active
-
2013
- 2013-06-06 ZA ZA2013/04150A patent/ZA201304150B/en unknown
-
2015
- 2015-07-06 JP JP2015135252A patent/JP6102991B2/ja not_active Expired - Fee Related
- 2015-09-19 US US14/859,254 patent/US20160083412A1/en not_active Abandoned
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PSEA | Patent sealed | ||
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 3 YEARS UNTIL 03 FEB 2018 BY HOULIHAN2 Effective date: 20160225 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 03 FEB 2019 BY HOULIHAN2 Effective date: 20180104 |
|
| LAPS | Patent lapsed | ||
| S35A | Application for proceedings under section 35 (restoration of lapsed patents) | ||
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 03 FEB 2021 BY HOULIHAN2 PTY LTD Effective date: 20200128 |
|
| S35R | Proceedings under section 35 (restoration of lapsed patents): patent restored | ||
| LAPS | Patent lapsed |