HUE036658T2 - Ketolid-származékok - Google Patents

Ketolid-származékok

Info

Publication number
HUE036658T2
HUE036658T2 HUE11708092A HUE11708092A HUE036658T2 HU E036658 T2 HUE036658 T2 HU E036658T2 HU E11708092 A HUE11708092 A HU E11708092A HU E11708092 A HUE11708092 A HU E11708092A HU E036658 T2 HUE036658 T2 HU E036658T2
Authority
HU
Hungary
Prior art keywords
ketolide compounds
ketolide
compounds
Prior art date
Application number
HUE11708092A
Other languages
English (en)
Inventor
Bharat Trivedi
Prasad Deshpande
Ravikumar Tadiparthi
Sunil Gupta
Santosh Diwakar
Shivaji Pawar
Vijay Patil
Deepak Dekhane
Mahesh Patel
Satish Bhavsar
Amit Mishra
Manish Solanki
Mohammad Jafri
Sachin Bhagwat
Original Assignee
Wockhardt Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wockhardt Ltd filed Critical Wockhardt Ltd
Publication of HUE036658T2 publication Critical patent/HUE036658T2/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00Compounds containing boron, silicon, or a metal, e.g. chelates, vitamin B12
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HUE11708092A 2010-12-09 2011-02-03 Ketolid-származékok HUE036658T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN3352MU2010 2010-12-09

Publications (1)

Publication Number Publication Date
HUE036658T2 true HUE036658T2 (hu) 2018-07-30

Family

ID=54259620

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE11708092A HUE036658T2 (hu) 2010-12-09 2011-02-03 Ketolid-származékok

Country Status (18)

Country Link
US (2) US9175031B2 (hu)
EP (2) EP3216798A3 (hu)
JP (2) JP5851516B2 (hu)
KR (1) KR101657751B1 (hu)
CN (2) CN105669803A (hu)
AU (1) AU2011340204B2 (hu)
BR (1) BR112013014392B1 (hu)
CA (2) CA2964104A1 (hu)
DK (1) DK2673285T3 (hu)
ES (1) ES2642287T3 (hu)
HU (1) HUE036658T2 (hu)
MX (1) MX348084B (hu)
NZ (1) NZ623574A (hu)
PL (1) PL2673285T3 (hu)
PT (1) PT2673285T (hu)
RU (1) RU2601550C2 (hu)
WO (1) WO2012076989A1 (hu)
ZA (1) ZA201304150B (hu)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ587490A (en) * 2010-08-20 2013-03-28 Greentide Ltd Anti-Microbial Compounds containing compounds with a sugar substituent
US8993739B2 (en) * 2011-03-22 2015-03-31 Wockhardt Ltd. Process for preparation of ketolide compounds
US9346828B2 (en) 2013-06-07 2016-05-24 Wisconsin Alumni Research Foundation Forazolines, compositions thereof and uses thereof
NZ739211A (en) * 2015-07-27 2019-05-31 Chong Kun Dang Pharmaceutical Corp 1,3,4-oxadiazole amide derivative compound as histone deacetylase 6 inhibitor, and pharmaceutical composition containing same
EP3328843B1 (en) 2015-07-27 2022-10-26 Chong Kun Dang Pharmaceutical Corp. 1,3,4-oxadiazole sulfonamide derivative compounds as histone deacetylase 6 inhibitor, and the pharmaceutical composition comprising the same
WO2017018805A1 (en) 2015-07-27 2017-02-02 Chong Kun Dang Pharmaceutical Corp. 1,3,4-oxadiazole sulfamide derivative compounds as histone deacetylase 6 inhibitor, and the pharmaceutical composition comprising the same
KR101799010B1 (ko) 2015-08-04 2017-11-17 주식회사 종근당 히스톤 탈아세틸화효소 6 억제제로서의 1,3,4-옥사다이아졸 유도체 화합물 및 이를 포함하는 약제학적 조성물
PL3362445T3 (pl) 2015-10-12 2023-08-07 Chong Kun Dang Pharmaceutical Corp. Związki będące pochodnymi oksadiazoloamin jako inhibitor deacetylazy histonowej 6 oraz kompozycja farmaceutyczna obejmujące takie związki
EP3402487A1 (en) * 2016-01-12 2018-11-21 Wockhardt Limited Pharmaceutical compositions for the treatment of bacterial infections
US10485812B2 (en) * 2016-01-12 2019-11-26 Wockhardt Limited Stable antibacterial composition
RU2018129198A (ru) * 2016-01-12 2020-02-13 Вокхардт Лимитед Фармацевтические композиции
EP3596097A1 (en) * 2017-03-16 2020-01-22 Wockhardt Limited A process for preparing ketolide compounds
KR102316234B1 (ko) 2018-07-26 2021-10-22 주식회사 종근당 히스톤 탈아세틸화효소 6 억제제로서의 1,3,4-옥사다이아졸 유도체 화합물 및 이를 포함하는 약제학적 조성물
AU2020380926A1 (en) * 2019-11-05 2022-05-26 Dermira, Inc. MrgprX2 antagonists and uses thereof

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2473525A1 (fr) 1980-01-11 1981-07-17 Roussel Uclaf Nouvelles oximes derivees de l'erythromycine, leur procede de preparation et leur application comme medicaments
US4331803A (en) 1980-06-04 1982-05-25 Taisho Pharmaceutical Co., Ltd. Novel erythromycin compounds
SI8110592A8 (en) 1981-03-06 1996-06-30 Pliva Pharm & Chem Works Process for preparing of n-methyl-11-aza-10-deoxo-10-dihydroerythromycine a and derivatives thereof
FR2719587B1 (fr) 1994-05-03 1996-07-12 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
ATE296308T1 (de) 1996-09-04 2005-06-15 Abbott Lab 6-o-substituierte ketoliden mit antibakteriellen wirkung
WO1999021870A1 (en) * 1997-10-29 1999-05-06 Taisho Pharmaceutical Co., Ltd. Erythromycin a 11, 12-carbamate derivatives
HRP980189B1 (en) * 1998-04-06 2004-04-30 Pliva Pharm & Chem Works Novel 15-membered lactams ketolides
FR2777282B1 (fr) * 1998-04-08 2001-04-20 Hoechst Marion Roussel Inc Nouveaux derives de la 2-fluoro 3-de((2,6-dideoxy 3-c-methyl 3-0-methyl-alpha-l-ribohexopyranosyl) oxyl) 6-o-methyl 3-oxo erythromycine, leur procede de preparation et leur application a la synthese de principes actifs de medicaments
EP1313751B1 (en) 2000-08-22 2008-09-17 Basilea Pharmaceutica AG New macrolides with antibacterial activity
CN1492874A (zh) * 2000-12-21 2004-04-28 大环内酯
GB0031312D0 (en) 2000-12-21 2001-02-07 Glaxo Group Ltd Macrolides
GB0127349D0 (en) 2001-11-14 2002-01-02 Glaxo Group Ltd Macrolides
US6995143B2 (en) 2002-02-28 2006-02-07 Basilea Pharmaceutica Ag Macrolides with antibacterial activity
US6727229B2 (en) 2002-08-19 2004-04-27 Enanta Pharmaceuticals, Inc. 11,12-substituted lactone ketolide derivatives having antibacterial activity
WO2004108744A2 (en) * 2003-05-19 2004-12-16 Prasad K Deshpande Azalides and azaketolides having antimicrobial activity
WO2006080954A1 (en) * 2004-07-28 2006-08-03 Ranbaxy Laboratories Limited Ketolide derivatives as antibacterial agents
EP2056844A4 (en) * 2006-08-24 2010-11-24 Wockhardt Research Center NEW MACROLIDS AND KETOLIDS WITH ANTIMICROBIAL EFFECT
US20090075915A1 (en) * 2007-09-17 2009-03-19 In Jong Kim 6,11-bicyclolides: bridged biaryl macrolide derivatives
US8552162B2 (en) * 2008-05-09 2013-10-08 Enanta Pharmaceuticals, Inc. Processes for the preparation of 2 fluoro 6-11 bicyclic erythromycin derivatives
WO2010136971A1 (en) * 2009-05-27 2010-12-02 Wockhardt Research Centre Ketolide compounds having antimicrobial activity

Also Published As

Publication number Publication date
US9175031B2 (en) 2015-11-03
RU2013131234A (ru) 2015-01-20
US20160083412A1 (en) 2016-03-24
EP2673285A1 (en) 2013-12-18
CN103384676B (zh) 2016-02-03
MX2013006461A (es) 2013-10-01
PT2673285T (pt) 2017-10-19
US20140005133A1 (en) 2014-01-02
EP3216798A3 (en) 2017-10-25
NZ623574A (en) 2015-07-31
AU2011340204A1 (en) 2013-07-04
CA2964104A1 (en) 2012-06-14
CA2820451C (en) 2017-12-12
MX348084B (es) 2017-05-26
DK2673285T3 (en) 2017-10-16
AU2011340204B2 (en) 2016-04-14
JP6102991B2 (ja) 2017-03-29
CA2820451A1 (en) 2012-06-14
WO2012076989A1 (en) 2012-06-14
JP2015172085A (ja) 2015-10-01
CN103384676A (zh) 2013-11-06
BR112013014392B1 (pt) 2021-09-21
EP3216798A2 (en) 2017-09-13
JP5851516B2 (ja) 2016-02-03
JP2013544877A (ja) 2013-12-19
CN105669803A (zh) 2016-06-15
EP2673285B1 (en) 2017-07-19
BR112013014392A2 (pt) 2016-07-19
ES2642287T3 (es) 2017-11-16
PL2673285T3 (pl) 2017-12-29
RU2601550C2 (ru) 2016-11-10
ZA201304150B (en) 2014-11-26
KR101657751B1 (ko) 2016-09-19
KR20130112911A (ko) 2013-10-14

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