NZ585116A - Extrusion process for making compositions with poorly compressible therapeutic compounds e.g. metformin hydrochloride - Google Patents
Extrusion process for making compositions with poorly compressible therapeutic compounds e.g. metformin hydrochlorideInfo
- Publication number
- NZ585116A NZ585116A NZ585116A NZ58511606A NZ585116A NZ 585116 A NZ585116 A NZ 585116A NZ 585116 A NZ585116 A NZ 585116A NZ 58511606 A NZ58511606 A NZ 58511606A NZ 585116 A NZ585116 A NZ 585116A
- Authority
- NZ
- New Zealand
- Prior art keywords
- hydrochloride
- acid
- therapeutic compound
- sulfate
- mixture
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title claims abstract description 112
- 230000001225 therapeutic effect Effects 0.000 title claims abstract description 109
- 239000000203 mixture Substances 0.000 title claims abstract description 47
- 238000000034 method Methods 0.000 title claims abstract description 32
- 230000008569 process Effects 0.000 title claims abstract description 21
- XZWYZXLIPXDOLR-UHFFFAOYSA-N metformin hydrochloride Natural products CN(C)C(=N)NC(N)=N XZWYZXLIPXDOLR-UHFFFAOYSA-N 0.000 title description 10
- OETHQSJEHLVLGH-UHFFFAOYSA-N metformin hydrochloride Chemical compound Cl.CN(C)C(=N)N=C(N)N OETHQSJEHLVLGH-UHFFFAOYSA-N 0.000 title description 6
- 229960004329 metformin hydrochloride Drugs 0.000 title description 6
- 238000001125 extrusion Methods 0.000 title description 3
- -1 soloctiditum Chemical compound 0.000 claims abstract description 44
- 239000008194 pharmaceutical composition Substances 0.000 claims abstract description 29
- 229920000642 polymer Polymers 0.000 claims abstract description 20
- 239000008187 granular material Substances 0.000 claims abstract description 17
- 238000002844 melting Methods 0.000 claims abstract description 17
- 230000008018 melting Effects 0.000 claims abstract description 17
- 239000006186 oral dosage form Substances 0.000 claims abstract description 13
- 238000010438 heat treatment Methods 0.000 claims abstract description 12
- KWGRBVOPPLSCSI-WPRPVWTQSA-N (-)-ephedrine Chemical compound CN[C@@H](C)[C@H](O)C1=CC=CC=C1 KWGRBVOPPLSCSI-WPRPVWTQSA-N 0.000 claims abstract description 8
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 claims abstract description 8
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims abstract description 8
- RPTUSVTUFVMDQK-UHFFFAOYSA-N Hidralazin Chemical compound C1=CC=C2C(NN)=NN=CC2=C1 RPTUSVTUFVMDQK-UHFFFAOYSA-N 0.000 claims abstract description 8
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 claims abstract description 8
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- KWGRBVOPPLSCSI-UHFFFAOYSA-N d-ephedrine Natural products CNC(C)C(O)C1=CC=CC=C1 KWGRBVOPPLSCSI-UHFFFAOYSA-N 0.000 claims abstract description 8
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 claims abstract description 8
- LNEPOXFFQSENCJ-UHFFFAOYSA-N haloperidol Chemical compound C1CC(O)(C=2C=CC(Cl)=CC=2)CCN1CCCC(=O)C1=CC=C(F)C=C1 LNEPOXFFQSENCJ-UHFFFAOYSA-N 0.000 claims abstract description 8
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- 229960002085 oxycodone Drugs 0.000 claims abstract description 8
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- DHHVAGZRUROJKS-UHFFFAOYSA-N phentermine Chemical compound CC(C)(N)CC1=CC=CC=C1 DHHVAGZRUROJKS-UHFFFAOYSA-N 0.000 claims abstract description 8
- LXNHXLLTXMVWPM-UHFFFAOYSA-N pyridoxine Chemical compound CC1=NC=C(CO)C(CO)=C1O LXNHXLLTXMVWPM-UHFFFAOYSA-N 0.000 claims abstract description 8
- ZFXYFBGIUFBOJW-UHFFFAOYSA-N theophylline Chemical compound O=C1N(C)C(=O)N(C)C2=C1NC=N2 ZFXYFBGIUFBOJW-UHFFFAOYSA-N 0.000 claims abstract description 8
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- 238000004898 kneading Methods 0.000 claims abstract description 5
- DBGIVFWFUFKIQN-UHFFFAOYSA-N (+-)-Fenfluramine Chemical compound CCNC(C)CC1=CC=CC(C(F)(F)F)=C1 DBGIVFWFUFKIQN-UHFFFAOYSA-N 0.000 claims abstract description 4
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- AKNNEGZIBPJZJG-MSOLQXFVSA-N (-)-noscapine Chemical compound CN1CCC2=CC=3OCOC=3C(OC)=C2[C@@H]1[C@@H]1C2=CC=C(OC)C(OC)=C2C(=O)O1 AKNNEGZIBPJZJG-MSOLQXFVSA-N 0.000 claims abstract description 4
- YKFCISHFRZHKHY-NGQGLHOPSA-N (2s)-2-amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoic acid;trihydrate Chemical compound O.O.O.OC(=O)[C@](N)(C)CC1=CC=C(O)C(O)=C1.OC(=O)[C@](N)(C)CC1=CC=C(O)C(O)=C1 YKFCISHFRZHKHY-NGQGLHOPSA-N 0.000 claims abstract description 4
- ZGSZBVAEVPSPFM-HYTSPMEMSA-N (4r,4ar,7s,7ar,12bs)-9-methoxy-3-methyl-2,4,4a,5,6,7,7a,13-octahydro-1h-4,12-methanobenzofuro[3,2-e]isoquinoline-7-ol;(2r,3r)-2,3-dihydroxybutanedioic acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O.C([C@H]1[C@H](N(CC[C@@]112)C)C3)C[C@H](O)[C@@H]1OC1=C2C3=CC=C1OC ZGSZBVAEVPSPFM-HYTSPMEMSA-N 0.000 claims abstract description 4
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- CDOUZKKFHVEKRI-UHFFFAOYSA-N 3-bromo-n-[(prop-2-enoylamino)methyl]propanamide Chemical compound BrCCC(=O)NCNC(=O)C=C CDOUZKKFHVEKRI-UHFFFAOYSA-N 0.000 claims abstract description 4
- MEAPRSDUXBHXGD-UHFFFAOYSA-N 3-chloro-n-(4-propan-2-ylphenyl)propanamide Chemical compound CC(C)C1=CC=C(NC(=O)CCCl)C=C1 MEAPRSDUXBHXGD-UHFFFAOYSA-N 0.000 claims abstract description 4
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- 229930000680 A04AD01 - Scopolamine Natural products 0.000 claims abstract description 4
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- YAVZHCFFUATPRK-YZPBMOCRSA-N Erythromycin stearate Chemical compound CCCCCCCCCCCCCCCCCC(O)=O.O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 YAVZHCFFUATPRK-YZPBMOCRSA-N 0.000 claims abstract description 4
- PLDUPXSUYLZYBN-UHFFFAOYSA-N Fluphenazine Chemical compound C1CN(CCO)CCN1CCCN1C2=CC(C(F)(F)F)=CC=C2SC2=CC=CC=C21 PLDUPXSUYLZYBN-UHFFFAOYSA-N 0.000 claims abstract description 4
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- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US67958705P | 2005-05-10 | 2005-05-10 | |
| US69315505P | 2005-06-23 | 2005-06-23 | |
| NZ562304A NZ562304A (en) | 2005-05-10 | 2006-05-08 | Extrusion process for making compositions with poorly compressible therapeutic compounds e.g. metformin hydrochloride |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ585116A true NZ585116A (en) | 2011-12-22 |
Family
ID=37022916
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ585116A NZ585116A (en) | 2005-05-10 | 2006-05-08 | Extrusion process for making compositions with poorly compressible therapeutic compounds e.g. metformin hydrochloride |
| NZ562304A NZ562304A (en) | 2005-05-10 | 2006-05-08 | Extrusion process for making compositions with poorly compressible therapeutic compounds e.g. metformin hydrochloride |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ562304A NZ562304A (en) | 2005-05-10 | 2006-05-08 | Extrusion process for making compositions with poorly compressible therapeutic compounds e.g. metformin hydrochloride |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US20100152299A1 (enExample) |
| EP (1) | EP1881819A1 (enExample) |
| JP (1) | JP5400377B2 (enExample) |
| KR (2) | KR20080007357A (enExample) |
| CN (1) | CN102552162A (enExample) |
| AU (2) | AU2006244213B2 (enExample) |
| BR (1) | BRPI0608609A2 (enExample) |
| CA (1) | CA2607624A1 (enExample) |
| IL (1) | IL186456A0 (enExample) |
| MA (1) | MA29465B1 (enExample) |
| MX (1) | MX2007014041A (enExample) |
| NO (1) | NO20076298L (enExample) |
| NZ (2) | NZ585116A (enExample) |
| RU (1) | RU2405539C2 (enExample) |
| TN (1) | TNSN07415A1 (enExample) |
| WO (1) | WO2006122021A1 (enExample) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7776314B2 (en) | 2002-06-17 | 2010-08-17 | Grunenthal Gmbh | Abuse-proofed dosage system |
| US20070048228A1 (en) | 2003-08-06 | 2007-03-01 | Elisabeth Arkenau-Maric | Abuse-proofed dosage form |
| DE10336400A1 (de) | 2003-08-06 | 2005-03-24 | Grünenthal GmbH | Gegen Missbrauch gesicherte Darreichungsform |
| DE10361596A1 (de) | 2003-12-24 | 2005-09-29 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
| DE102005005446A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Bruchfeste Darreichungsformen mit retardierter Freisetzung |
| DE102004032049A1 (de) | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Gegen Missbrauch gesicherte, orale Darreichungsform |
| DE102005005449A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
| GB2447898B (en) * | 2007-03-24 | 2011-08-17 | Reckitt Benckiser Healthcare | A tablet having improved stability with at least two actives |
| EP2249811A1 (en) | 2008-01-25 | 2010-11-17 | Grünenthal GmbH | Pharmaceutical dosage form |
| RU2010148536A (ru) * | 2008-04-30 | 2012-06-10 | Новартис АГ (CH) | Способ непрерывного изготовления фармацевтических композиций |
| MX2010014566A (es) * | 2008-07-03 | 2011-02-15 | Novartis Ag | Proceso de granulacion de fundido. |
| AR077493A1 (es) | 2009-07-22 | 2011-08-31 | Gruenenthal Gmbh | Composicion farmaceutica extruida en caliente con liberacion controlada. procedimiento de preparacion |
| SI2456424T1 (sl) | 2009-07-22 | 2013-10-30 | Gruenenthal Gmbh | Oksidacijsko stabilizirana odmerna oblika, varna pred zlorabo |
| PL2611425T3 (pl) | 2010-09-02 | 2014-09-30 | Gruenenthal Gmbh | Odporna na ingerencję postać dawki zawierająca polimer anionowy |
| MX2013002377A (es) | 2010-09-02 | 2013-04-29 | Gruenenthal Gmbh | Forma de dosificacion resistente a manipulacion que comprende una sal inorganica. |
| JP2014524925A (ja) | 2011-07-29 | 2014-09-25 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 即時薬剤放出を提供するタンパーレジスタント錠剤 |
| EP2736497B1 (en) | 2011-07-29 | 2017-08-23 | Grünenthal GmbH | Tamper-resistant tablet providing immediate drug release |
| MX356421B (es) | 2012-02-28 | 2018-05-29 | Gruenenthal Gmbh | Forma de dosificacion resistente a la manipulacion indebida que comprende un compuesto farmacologicamente activo y un polimero anionico. |
| AR090695A1 (es) | 2012-04-18 | 2014-12-03 | Gruenenthal Gmbh | Forma de dosificacion farmaceutica resistente a la adulteracion y resistente a la liberacion inmediata de la dosis |
| US10064945B2 (en) | 2012-05-11 | 2018-09-04 | Gruenenthal Gmbh | Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc |
| GB201218012D0 (en) | 2012-10-08 | 2012-11-21 | Jagotec Ag | Dosage forms |
| US9737490B2 (en) | 2013-05-29 | 2017-08-22 | Grünenthal GmbH | Tamper resistant dosage form with bimodal release profile |
| MX371432B (es) | 2013-05-29 | 2020-01-30 | Gruenenthal Gmbh | Forma de dosificacion resistente al uso indebido que contiene una o mas particulas. |
| EA032465B1 (ru) | 2013-07-12 | 2019-05-31 | Грюненталь Гмбх | Защищенная от применения не по назначению пероральная фармацевтическая лекарственная форма, содержащая этиленвинилацетатный полимер, и способ ее изготовления |
| CA2919892C (en) | 2013-08-12 | 2019-06-18 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded immediate release abuse deterrent pill |
| BR112016010482B1 (pt) | 2013-11-26 | 2022-11-16 | Grünenthal GmbH | Preparação de uma composição farmacêutica em pó por meio de criomoagem |
| US9492444B2 (en) | 2013-12-17 | 2016-11-15 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
| WO2015095391A1 (en) | 2013-12-17 | 2015-06-25 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
| MX2016014738A (es) | 2014-05-12 | 2017-03-06 | Gruenenthal Gmbh | Formulacion en capsula de liberacion inmediata resistente a alteraciones que comprende tapentadol. |
| MX2016015417A (es) | 2014-05-26 | 2017-02-22 | Gruenenthal Gmbh | Multiparticulas protegidas contra vertido de dosis etanolico. |
| DK3169315T3 (da) | 2014-07-17 | 2020-08-10 | Pharmaceutical Manufacturing Res Services In | Væskefyldt doseringsform til forhindring af misbrug med øjeblikkelig frigivelse |
| JP2017531026A (ja) | 2014-10-20 | 2017-10-19 | ファーマシューティカル マニュファクチュアリング リサーチ サービシズ，インコーポレーテッド | 徐放性乱用抑止性液体充填剤形 |
| WO2016170093A1 (en) | 2015-04-24 | 2016-10-27 | Grünenthal GmbH | Tamper-resistant fixed dose combination providing fast release of two drugs from particles and a matrix |
| BR112017022856A2 (pt) | 2015-04-24 | 2018-07-17 | Gruenenthal Gmbh | combinação de dose fixa inviolável que proporciona rápida liberação de duas drogas a partir de partículas |
| EA035434B1 (ru) | 2015-04-24 | 2020-06-15 | Грюненталь Гмбх | Защищенная от применения не по назначению лекарственная форма с немедленным высвобождением и устойчивостью к экстракции растворителями |
| BR112017022846A2 (pt) | 2015-04-24 | 2018-07-17 | Gruenenthal Gmbh | combinação de dose fixa inviolável que proporciona rápida liberação de dois fármacos de partículas diferentes |
| WO2017042325A1 (en) | 2015-09-10 | 2017-03-16 | Grünenthal GmbH | Protecting oral overdose with abuse deterrent immediate release formulations |
| DE102018010063A1 (de) | 2018-03-16 | 2019-09-19 | Ludwig-Maximilians-Universität München | Herstellung vesikulärer Phospholipid-Gele durch Schnecken-Extrusion |
| CN108888599B (zh) * | 2018-07-26 | 2021-06-08 | 国药集团致君（深圳）制药有限公司 | 双氯芬酸钠缓释组合物及其制备方法 |
| AU2021391823A1 (en) | 2020-12-03 | 2023-06-29 | Battelle Memorial Institute | Polymer nanoparticle and dna nanostructure compositions and methods for non-viral delivery |
| IL307454A (en) | 2021-04-07 | 2023-12-01 | Battelle Memorial Institute | Technologies for rapid design, construction, testing, learning to identify and use non-viral vectors |
| CN118234388A (zh) * | 2021-11-16 | 2024-06-21 | 帝斯曼知识产权资产管理有限公司 | 可通过连续熔融造粒获得的高效力颗粒 |
| EP4432861A1 (en) * | 2021-11-16 | 2024-09-25 | DSM IP Assets B.V. | Granule comprising encapsulated active ingredients |
| WO2023145869A1 (ja) * | 2022-01-31 | 2023-08-03 | 住友精化株式会社 | 製剤用組成物の製造方法及び製剤の製造方法 |
| WO2023145871A1 (ja) * | 2022-01-31 | 2023-08-03 | 住友精化株式会社 | 製剤用組成物の製造方法及び製剤の製造方法 |
| TW202412735A (zh) * | 2022-08-31 | 2024-04-01 | 義大利商沙克米機械合作伊莫拉公司 | 製造固體藥劑的方法及裝置 |
| WO2025072751A1 (en) | 2023-09-29 | 2025-04-03 | Battelle Memorial Institute | Polymer nanoparticle compositions for in vivo expression of polypeptides |
| WO2025122954A1 (en) | 2023-12-08 | 2025-06-12 | Battelle Memorial Institute | Use of dna origami nanostructures for molecular information based data storage systems |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2571046B1 (fr) * | 1984-10-03 | 1987-10-16 | Roquette Freres | Procede de preparation de mannitol granulaire directement compressible |
| US5965161A (en) * | 1994-11-04 | 1999-10-12 | Euro-Celtique, S.A. | Extruded multi-particulates |
| DE19504832A1 (de) * | 1995-02-14 | 1996-08-22 | Basf Ag | Feste Wirkstoff-Zubereitungen |
| DE19504831A1 (de) * | 1995-02-14 | 1996-09-05 | Basf Ag | Feste Wirkstoffzubereitungen enthaltend Hydroxypropylcellulose |
| DE19509806A1 (de) * | 1995-03-21 | 1996-09-26 | Basf Ag | Lagerstabile Arzneiformen |
| DE19721467A1 (de) * | 1997-05-22 | 1998-11-26 | Basf Ag | Verfahren zur Herstellung kleinteiliger Zubereitungen biologisch aktiver Stoffe |
| HN1998000115A (es) * | 1997-08-21 | 1999-06-02 | Warner Lambert Co | Formas de dosificación farmacéuticas sólidas |
| DE19934610A1 (de) * | 1999-07-23 | 2001-01-25 | Bayer Ag | Schnellfreisetzende Extrudate und Verfahren zu ihrer Herstellung sowie daraus erhältliche Zubereitungen |
| JP2004510716A (ja) * | 2000-10-02 | 2004-04-08 | ユーエスヴイ リミテッド | メトフォルミン含有持続性放出薬理組成物とその製造方法 |
| WO2003004009A1 (en) * | 2001-07-02 | 2003-01-16 | Geneva Pharmaceuticals, Inc. | Pharmaceutical composition |
| IN192180B (enExample) * | 2001-09-28 | 2004-03-06 | Ranbaxy Lab | |
| RU2004108219A (ru) * | 2001-09-28 | 2005-03-10 | Сан Фармасьютикл Индастриз Лимитид (In) | Лекарственная форма для лечения сахарного диабета |
| FR2858556B1 (fr) * | 2003-08-06 | 2006-03-10 | Galenix Innovations | Composition pharmaceutique solide dispersible et/ou orodispersible non pelliculee contenant au moins le principe actif metformine, et procede de preparation |
| DE102005005446A1 (de) * | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Bruchfeste Darreichungsformen mit retardierter Freisetzung |
| US20070098778A1 (en) * | 2004-03-02 | 2007-05-03 | Abeille Pharmaceuticals, Inc. | Co-formulations or kits of bioactive agents |
| JOP20180109A1 (ar) * | 2005-09-29 | 2019-01-30 | Novartis Ag | تركيبة جديدة |
| EP1968553A2 (en) * | 2005-11-09 | 2008-09-17 | Novartis AG | Process for making pharmaceutical compositions with a transient plasticizer |
-
2006
- 2006-05-08 WO PCT/US2006/017708 patent/WO2006122021A1/en not_active Ceased
- 2006-05-08 EP EP06759308A patent/EP1881819A1/en not_active Withdrawn
- 2006-05-08 KR KR1020077026095A patent/KR20080007357A/ko not_active Ceased
- 2006-05-08 US US11/909,509 patent/US20100152299A1/en not_active Abandoned
- 2006-05-08 MX MX2007014041A patent/MX2007014041A/es active IP Right Grant
- 2006-05-08 NZ NZ585116A patent/NZ585116A/en not_active IP Right Cessation
- 2006-05-08 AU AU2006244213A patent/AU2006244213B2/en not_active Ceased
- 2006-05-08 RU RU2007145522/15A patent/RU2405539C2/ru not_active IP Right Cessation
- 2006-05-08 KR KR1020137031633A patent/KR20130135403A/ko not_active Ceased
- 2006-05-08 CA CA002607624A patent/CA2607624A1/en not_active Abandoned
- 2006-05-08 NZ NZ562304A patent/NZ562304A/en not_active IP Right Cessation
- 2006-05-08 CN CN2011103445944A patent/CN102552162A/zh active Pending
- 2006-05-08 BR BRPI0608609-8A patent/BRPI0608609A2/pt not_active IP Right Cessation
- 2006-05-08 JP JP2008511233A patent/JP5400377B2/ja not_active Expired - Fee Related
-
2007
- 2007-10-07 IL IL186456A patent/IL186456A0/en unknown
- 2007-11-09 TN TNP2007000415A patent/TNSN07415A1/en unknown
- 2007-11-20 MA MA30393A patent/MA29465B1/fr unknown
- 2007-12-06 NO NO20076298A patent/NO20076298L/no not_active Application Discontinuation
-
2010
- 2010-08-12 AU AU2010212296A patent/AU2010212296B2/en not_active Ceased
-
2011
- 2011-11-30 US US13/307,864 patent/US20120077879A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CN102552162A (zh) | 2012-07-11 |
| AU2010212296A1 (en) | 2010-09-02 |
| EP1881819A1 (en) | 2008-01-30 |
| JP2008540540A (ja) | 2008-11-20 |
| RU2405539C2 (ru) | 2010-12-10 |
| MA29465B1 (fr) | 2008-05-02 |
| IL186456A0 (en) | 2008-01-20 |
| JP5400377B2 (ja) | 2014-01-29 |
| KR20130135403A (ko) | 2013-12-10 |
| US20100152299A1 (en) | 2010-06-17 |
| AU2006244213B2 (en) | 2010-05-13 |
| KR20080007357A (ko) | 2008-01-18 |
| US20120077879A1 (en) | 2012-03-29 |
| AU2006244213A1 (en) | 2006-11-16 |
| CA2607624A1 (en) | 2006-11-16 |
| AU2010212296B2 (en) | 2011-06-16 |
| TNSN07415A1 (en) | 2009-03-17 |
| WO2006122021A1 (en) | 2006-11-16 |
| BRPI0608609A2 (pt) | 2010-01-19 |
| MX2007014041A (es) | 2008-02-11 |
| NZ562304A (en) | 2010-06-25 |
| NO20076298L (no) | 2007-12-06 |
| RU2007145522A (ru) | 2009-06-20 |
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Legal Events
| Date | Code | Title | Description |
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| PSEA | Patent sealed | ||
| RENW | Renewal (renewal fees accepted) | ||
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 3 YEARS UNTIL 08 MAY 2016 BY CPA GLOBAL Effective date: 20130405 |
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| LAPS | Patent lapsed |