AR077493A1 - Composicion farmaceutica extruida en caliente con liberacion controlada. procedimiento de preparacion - Google Patents

Composicion farmaceutica extruida en caliente con liberacion controlada. procedimiento de preparacion

Info

Publication number
AR077493A1
AR077493A1 ARP100102651A ARP100102651A AR077493A1 AR 077493 A1 AR077493 A1 AR 077493A1 AR P100102651 A ARP100102651 A AR P100102651A AR P100102651 A ARP100102651 A AR P100102651A AR 077493 A1 AR077493 A1 AR 077493A1
Authority
AR
Argentina
Prior art keywords
pharmaceutical tablet
preceding
active ingredient
extension
longitudinal direction
Prior art date
Application number
ARP100102651A
Other languages
English (en)
Inventor
Lutz Barnscheid
Eric Galia
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
Priority to EP09009499 priority Critical
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of AR077493A1 publication Critical patent/AR077493A1/es
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42332474&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR077493(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2031Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2095Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing

Abstract

Comprimido farmacéutico extruído en caliente con liberacion controlada de un ingrediente farmacologicamente activo (A) incluida en una matriz que comprende un polímero (C), presentando el comprimido una forma oblonga que comprende una direccion longitudinal de extension, una direccion transversal de extension ortogonal a la direccion longitudinal de extension, una cara frontal, una cara posterior opuesta y un borde circunferencial entre dichas cara frontal y posterior, en la que: - el nucleo del comprimido farmacéutico presenta una orientacion morfologica causada por la extrusion en caliente que es sustancialmente ortogonal respecto a la direccion longitudinal de extension de la forma de dosificacion, y/o la liberacion por unidad de área del ingrediente farmacologicamente activo (A) a través de la cara frontal y de la cara posterior opuesta es más rápida que la liberacion a partir del borde circunferencial. Reivindicacion 4: Un comprimido farmacéutico segun cualquiera de las reivindicaciones anteriores, en la que el ingrediente farmacologicamente activo (A) es un opioide. Reivindicacion 5: Un comprimido farmacéutico segun cualquiera de las reivindicaciones anteriores, en la que el polímero (C) es un oxido de polialquileno que presenta un peso molecular medio en peso de por lo menos 200.000 g/mol. Reivindicacion 8: Un comprimido farmacéutico segun cualquiera de las reivindicaciones anteriores que comprende un recubrimiento de una película.
ARP100102651A 2009-07-22 2010-07-21 Composicion farmaceutica extruida en caliente con liberacion controlada. procedimiento de preparacion AR077493A1 (es)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP09009499 2009-07-22

Publications (1)

Publication Number Publication Date
AR077493A1 true AR077493A1 (es) 2011-08-31

Family

ID=42332474

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP100102651A AR077493A1 (es) 2009-07-22 2010-07-21 Composicion farmaceutica extruida en caliente con liberacion controlada. procedimiento de preparacion

Country Status (21)

Country Link
US (1) US10080721B2 (es)
EP (1) EP2456427B1 (es)
JP (1) JP5667183B2 (es)
KR (1) KR101738369B1 (es)
CN (1) CN102573805A (es)
AR (1) AR077493A1 (es)
AU (1) AU2010275753B2 (es)
BR (1) BR112012001547A2 (es)
CA (1) CA2765971C (es)
CO (1) CO6470796A2 (es)
EC (1) ECSP12011597A (es)
ES (1) ES2534908T3 (es)
HK (1) HK1167811A1 (es)
IL (1) IL216526A (es)
MX (1) MX2012000317A (es)
NZ (1) NZ596667A (es)
PE (1) PE20121067A1 (es)
RU (1) RU2547555C2 (es)
TW (1) TW201105316A (es)
WO (1) WO2011009602A1 (es)
ZA (1) ZA201109445B (es)

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US20110038930A1 (en) 2011-02-17
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CA2765971A1 (en) 2011-01-27
EP2456427A1 (en) 2012-05-30
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AU2010275753B2 (en) 2014-08-21
BR112012001547A2 (pt) 2016-03-08
RU2547555C2 (ru) 2015-04-10
CN102573805A (zh) 2012-07-11
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WO2011009602A1 (en) 2011-01-27

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