NZ549963A - Substituted piperazines, (1,4) diazepines, and 2,5-diazabicyclo (2.2.1) heptanes as histamine H1 and/or H3 antagonists or histamine H3 reverse antagonists - Google Patents

Substituted piperazines, (1,4) diazepines, and 2,5-diazabicyclo (2.2.1) heptanes as histamine H1 and/or H3 antagonists or histamine H3 reverse antagonists

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Publication number
NZ549963A
NZ549963A NZ549963A NZ54996303A NZ549963A NZ 549963 A NZ549963 A NZ 549963A NZ 549963 A NZ549963 A NZ 549963A NZ 54996303 A NZ54996303 A NZ 54996303A NZ 549963 A NZ549963 A NZ 549963A
Authority
NZ
New Zealand
Prior art keywords
phenyl
oxy
piperidinyl
piperazine
propyl
Prior art date
Application number
NZ549963A
Other languages
English (en)
Inventor
Rachael Ancliff
Colin David Eldred
Yvonne C Fogden
Ashley Paul Hancock
Thomas Daniel Heightman
Heather Hobbs
Simon Teanby Hodgson
Matthew J Lindon
David Matthew Wilson
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of NZ549963A publication Critical patent/NZ549963A/en

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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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NZ549963A 2002-10-16 2003-10-14 Substituted piperazines, (1,4) diazepines, and 2,5-diazabicyclo (2.2.1) heptanes as histamine H1 and/or H3 antagonists or histamine H3 reverse antagonists NZ549963A (en)

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AU2003280380A1 (en) 2004-05-04
RU2005110061A (ru) 2006-01-20
MA27482A1 (fr) 2005-08-01
PL376477A1 (en) 2005-12-27
GB0224084D0 (en) 2002-11-27
US7615550B2 (en) 2009-11-10
RU2328494C2 (ru) 2008-07-10
ZA200502873B (en) 2006-07-26
US20060025404A1 (en) 2006-02-02
CN101070309A (zh) 2007-11-14
US20100075953A1 (en) 2010-03-25
MXPA05004078A (es) 2005-06-08
NO20051689D0 (no) 2005-04-05
KR20050049553A (ko) 2005-05-25
EP1567511A1 (en) 2005-08-31
CA2502249A1 (en) 2004-04-29
IS7782A (is) 2005-03-31
CN100400523C (zh) 2008-07-09
NZ539446A (en) 2006-11-30
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ZA200603604B (en) 2007-04-25
CN1726201A (zh) 2006-01-25

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