NO20051689L - Substituerte piperaziner, (1,4) diaszepiner og 2,5-diazabicyklo(2.2.1) heptaner som histamin H1 og/eller H3 antagonister eller histamin H3 revers antagonister - Google Patents
Substituerte piperaziner, (1,4) diaszepiner og 2,5-diazabicyklo(2.2.1) heptaner som histamin H1 og/eller H3 antagonister eller histamin H3 revers antagonisterInfo
- Publication number
- NO20051689L NO20051689L NO20051689A NO20051689A NO20051689L NO 20051689 L NO20051689 L NO 20051689L NO 20051689 A NO20051689 A NO 20051689A NO 20051689 A NO20051689 A NO 20051689A NO 20051689 L NO20051689 L NO 20051689L
- Authority
- NO
- Norway
- Prior art keywords
- histamine
- antagonists
- diaszepines
- heptanes
- diazabicyclo
- Prior art date
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- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
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- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
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Abstract
Foreliggende oppfinnelse vedrører nye piperazin- og azepinderivater med farmakologisk aktivitet, fremgangsmåter for fremstilling derav, sammensetninger som inneholder disse og anvendelse derav for behandling av nevrodegenerativeforstyrrelser inkludert Alzheimers sykdom.
Applications Claiming Priority (2)
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GBGB0224084.4A GB0224084D0 (en) | 2002-10-16 | 2002-10-16 | Novel compounds |
PCT/EP2003/011423 WO2004035556A1 (en) | 2002-10-16 | 2003-10-14 | Substituted piperazines, (1,4) diaszepines, and 2,5-diazabicyclo (2.2.1) heptanes as histamine h1 and/or h3 antagonists or histamine h3 reverse antagonists |
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NO20051689D0 NO20051689D0 (no) | 2005-04-05 |
NO20051689L true NO20051689L (no) | 2005-07-07 |
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US (2) | US7615550B2 (no) |
EP (1) | EP1567511A1 (no) |
JP (2) | JP2006508935A (no) |
KR (1) | KR20050049553A (no) |
CN (2) | CN100400523C (no) |
AU (1) | AU2003280380A1 (no) |
BR (1) | BR0315283A (no) |
CA (1) | CA2502249A1 (no) |
GB (1) | GB0224084D0 (no) |
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MA (1) | MA27482A1 (no) |
MX (1) | MXPA05004078A (no) |
NO (1) | NO20051689L (no) |
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RU (1) | RU2328494C2 (no) |
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ATE354568T1 (de) | 2000-08-08 | 2007-03-15 | Ortho Mcneil Pharm Inc | Nicht-imidazol aryloxypiperidine als h3 rezeptor liganden |
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GB0609897D0 (en) * | 2006-05-18 | 2006-06-28 | Glaxo Group Ltd | Compounds |
-
2002
- 2002-10-16 GB GBGB0224084.4A patent/GB0224084D0/en not_active Ceased
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2003
- 2003-10-14 NZ NZ549963A patent/NZ549963A/en unknown
- 2003-10-14 AU AU2003280380A patent/AU2003280380A1/en not_active Abandoned
- 2003-10-14 MX MXPA05004078A patent/MXPA05004078A/es unknown
- 2003-10-14 CN CNB2003801060141A patent/CN100400523C/zh not_active Expired - Fee Related
- 2003-10-14 CA CA002502249A patent/CA2502249A1/en not_active Abandoned
- 2003-10-14 NZ NZ539446A patent/NZ539446A/en unknown
- 2003-10-14 JP JP2004544241A patent/JP2006508935A/ja active Pending
- 2003-10-14 KR KR1020057006621A patent/KR20050049553A/ko not_active Application Discontinuation
- 2003-10-14 CN CNA2006101086109A patent/CN101070309A/zh active Pending
- 2003-10-14 EP EP03772221A patent/EP1567511A1/en not_active Withdrawn
- 2003-10-14 RU RU2005110061/04A patent/RU2328494C2/ru not_active IP Right Cessation
- 2003-10-14 US US10/531,758 patent/US7615550B2/en not_active Expired - Fee Related
- 2003-10-14 BR BR0315283-9A patent/BR0315283A/pt not_active IP Right Cessation
- 2003-10-14 WO PCT/EP2003/011423 patent/WO2004035556A1/en active Application Filing
- 2003-10-14 PL PL03376477A patent/PL376477A1/xx unknown
-
2005
- 2005-03-31 IS IS7782A patent/IS7782A/is unknown
- 2005-04-05 NO NO20051689A patent/NO20051689L/no not_active Application Discontinuation
- 2005-04-08 ZA ZA200502873A patent/ZA200502873B/en unknown
- 2005-04-29 MA MA28246A patent/MA27482A1/fr unknown
-
2006
- 2006-05-05 ZA ZA200603604A patent/ZA200603604B/en unknown
- 2006-08-28 JP JP2006231163A patent/JP2007016041A/ja active Pending
-
2009
- 2009-09-18 US US12/562,285 patent/US20100075953A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
JP2006508935A (ja) | 2006-03-16 |
IS7782A (is) | 2005-03-31 |
US7615550B2 (en) | 2009-11-10 |
EP1567511A1 (en) | 2005-08-31 |
RU2005110061A (ru) | 2006-01-20 |
US20060025404A1 (en) | 2006-02-02 |
MXPA05004078A (es) | 2005-06-08 |
CA2502249A1 (en) | 2004-04-29 |
PL376477A1 (en) | 2005-12-27 |
KR20050049553A (ko) | 2005-05-25 |
MA27482A1 (fr) | 2005-08-01 |
ZA200603604B (en) | 2007-04-25 |
NZ539446A (en) | 2006-11-30 |
ZA200502873B (en) | 2006-07-26 |
AU2003280380A1 (en) | 2004-05-04 |
US20100075953A1 (en) | 2010-03-25 |
NZ549963A (en) | 2008-03-28 |
WO2004035556A1 (en) | 2004-04-29 |
JP2007016041A (ja) | 2007-01-25 |
CN100400523C (zh) | 2008-07-09 |
RU2328494C2 (ru) | 2008-07-10 |
NO20051689D0 (no) | 2005-04-05 |
CN1726201A (zh) | 2006-01-25 |
GB0224084D0 (en) | 2002-11-27 |
CN101070309A (zh) | 2007-11-14 |
BR0315283A (pt) | 2005-08-30 |
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