NZ549570A - Tricyclic benzopyran compound as anti-arrhythmic agents - Google Patents

Tricyclic benzopyran compound as anti-arrhythmic agents

Info

Publication number
NZ549570A
NZ549570A NZ549570A NZ54957005A NZ549570A NZ 549570 A NZ549570 A NZ 549570A NZ 549570 A NZ549570 A NZ 549570A NZ 54957005 A NZ54957005 A NZ 54957005A NZ 549570 A NZ549570 A NZ 549570A
Authority
NZ
New Zealand
Prior art keywords
group
amino
npr
dihydro
halogen atom
Prior art date
Application number
NZ549570A
Other languages
English (en)
Inventor
Kazuhiko Ohrai
Osamu Uesugi
Takumi Okada
Yukihiro Shigeta
Tomoyuki Matsuda
Original Assignee
Nissan Chemical Ind Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nissan Chemical Ind Ltd filed Critical Nissan Chemical Ind Ltd
Priority to NZ585606A priority Critical patent/NZ585606A/en
Publication of NZ549570A publication Critical patent/NZ549570A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D515/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D515/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D515/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Dental Preparations (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NZ549570A 2004-03-23 2005-03-23 Tricyclic benzopyran compound as anti-arrhythmic agents NZ549570A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NZ585606A NZ585606A (en) 2004-03-23 2005-03-23 Tricyclic benzopyran compound as anti-arrhythmic agents

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2004084605 2004-03-23
PCT/JP2005/006004 WO2005090357A1 (en) 2004-03-23 2005-03-23 Tricyclic benzopyran compound as anti-arrhythmic agents

Publications (1)

Publication Number Publication Date
NZ549570A true NZ549570A (en) 2010-08-27

Family

ID=34962589

Family Applications (2)

Application Number Title Priority Date Filing Date
NZ549570A NZ549570A (en) 2004-03-23 2005-03-23 Tricyclic benzopyran compound as anti-arrhythmic agents
NZ585606A NZ585606A (en) 2004-03-23 2005-03-23 Tricyclic benzopyran compound as anti-arrhythmic agents

Family Applications After (1)

Application Number Title Priority Date Filing Date
NZ585606A NZ585606A (en) 2004-03-23 2005-03-23 Tricyclic benzopyran compound as anti-arrhythmic agents

Country Status (30)

Country Link
US (2) US7652008B2 (https=)
EP (1) EP1732929B1 (https=)
JP (1) JP4840594B2 (https=)
KR (2) KR101085979B1 (https=)
CN (3) CN102190661B (https=)
AT (1) ATE485299T1 (https=)
AU (2) AU2005223612B2 (https=)
BR (1) BRPI0508768A (https=)
CA (1) CA2558139C (https=)
CY (1) CY1111250T1 (https=)
CZ (1) CZ2006598A3 (https=)
DE (1) DE602005024245D1 (https=)
DK (1) DK1732929T3 (https=)
EG (1) EG27163A (https=)
ES (1) ES2353021T3 (https=)
HR (1) HRP20110005T1 (https=)
IL (1) IL177950A (https=)
MX (1) MXPA06010880A (https=)
NO (1) NO339495B1 (https=)
NZ (2) NZ549570A (https=)
PL (1) PL1732929T3 (https=)
PT (1) PT1732929E (https=)
RS (1) RS51742B (https=)
RU (1) RU2380370C2 (https=)
SI (1) SI1732929T1 (https=)
SK (1) SK287994B6 (https=)
TW (1) TWI352704B (https=)
UA (1) UA91189C2 (https=)
WO (1) WO2005090357A1 (https=)
ZA (1) ZA200607388B (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2353021T3 (es) * 2004-03-23 2011-02-24 Nissan Chemical Industries, Ltd. Compuesto de benzopirano tricíclico como agentes anti-arrítmicos.
RU2448112C2 (ru) 2006-03-10 2012-04-20 Ниссан Кемикал Индастриз, Лтд. Способ получения оптически активного соединения оксида хромена
TW201022223A (en) * 2008-08-14 2010-06-16 Nissan Chemical Ind Ltd Di-substituted benzopyrane compound
KR101703202B1 (ko) * 2009-04-30 2017-02-06 닛산 가가쿠 고교 가부시키 가이샤 3환성 벤조피란 화합물의 신규한 결정형태 및 그 제조방법
US8431576B2 (en) 2009-06-25 2013-04-30 Alkermes Pharma Ireland Limited Heterocyclic compounds for the treatment of neurological and psychological disorders
JPWO2014051077A1 (ja) * 2012-09-27 2016-08-25 日産化学工業株式会社 高純度の含窒素複素環化合物の製造方法
JP6202280B2 (ja) * 2012-09-27 2017-09-27 日産化学工業株式会社 含窒素複素環n−オキシド化合物の製造方法
JPWO2015012271A1 (ja) * 2013-07-25 2017-03-02 日産化学工業株式会社 複素環化合物の製造方法
US11168094B2 (en) 2017-01-06 2021-11-09 Azcuris Co., Ltd. Quinolinone derivative and pharmaceutical composition for preventing or treating allergic diseases such as asthma or atopic dermatitis including the quinolinone derivative as active ingredient
EP3761983A1 (en) 2018-03-05 2021-01-13 Alkermes Pharma Ireland Limited Aripiprazole dosing strategy
CN108727261B (zh) * 2018-06-21 2021-09-24 济南大学 一种硝基取代喹那啶的制备方法
US20220071951A1 (en) * 2018-12-28 2022-03-10 Osaka University Therapeutic agent for inherited bradyarrhythmia
RU2754610C1 (ru) * 2020-04-14 2021-09-03 Георгий Викторович ТЕЦ Препарат для лечения заболеваний, вызванных бактериями
CN115916201B (zh) * 2020-06-26 2024-09-17 国立大学法人大阪大学 药剂诱发性心动过缓及心动过缓性心律失常治疗药

Family Cites Families (22)

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Publication number Priority date Publication date Assignee Title
ZM7682A1 (en) 1981-09-25 1983-05-23 Beecham Group Plc Active compounds
JPS5867683U (ja) 1981-10-28 1983-05-09 株式会社ナムコ 歩行ロボツト
JPH0699439B2 (ja) * 1988-02-03 1994-12-07 日産化学工業株式会社 ピラノベンゾオキサジアゾール誘導体
JP2658198B2 (ja) * 1988-06-23 1997-09-30 日産化学工業株式会社 ピラノベンゾトリアゾール誘導体
JP2876712B2 (ja) * 1989-07-17 1999-03-31 日産化学工業株式会社 光学活性ピラノベンゾオキサジアゾール誘導体
US5097037A (en) * 1989-07-17 1992-03-17 Nissan Chemical Industries, Ltd. Process for the optical resolution of pyranobenzoxadiazole compounds
US5164509A (en) * 1990-11-26 1992-11-17 E. R. Squibb & Sons, Inc. Benzodiazolo analogs
JPH07300414A (ja) * 1993-04-02 1995-11-14 Nissan Chem Ind Ltd 心不全治療薬
UA27973C2 (uk) * 1993-04-02 2000-10-16 Ніссан Кемікал Індастріз Лтд Лікарський засіб для лікування серцевої недостатності
JP2734457B2 (ja) 1994-02-23 1998-03-30 日産化学工業株式会社 不斉エポキシ化反応
WO1995034547A1 (en) * 1994-06-10 1995-12-21 Smithkline Beecham Plc C-4 amide substituted compounds and their use as therapeutic agents
HRP970255B1 (en) * 1996-05-15 2003-10-31 Hoechst Ag Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents as well as medicaments containing them
US6486178B1 (en) 1998-06-03 2002-11-26 Nissan Chemical Industries, Ltd. Indane derivatives
AU5444499A (en) 1998-09-01 2000-03-21 Nissan Chemical Industries Ltd. Benzoxazine derivatives
AU2830800A (en) 1999-03-25 2000-10-16 Nissan Chemical Industries Ltd. Chroman derivatives
CA2383583C (en) * 1999-09-17 2009-04-07 Nissan Chemical Industries, Ltd. Benzopyran derivative
EP1214307B1 (en) 1999-09-24 2004-04-07 Nissan Chemical Industries, Ltd. 4-oxybenzopyran derivative
US6677371B1 (en) 1999-10-05 2004-01-13 Nissan Chemical Industries, Ltd. 4-oxybenzopyran derivative
TW589305B (en) 2001-02-14 2004-06-01 Nissan Chemical Ind Ltd 4-aminobenzopyran derivatives
EP1401823B1 (en) 2001-06-25 2005-10-05 Nissan Chemical Industries, Ltd. Substituted benzopyran derivatives against arrhythmia
WO2003014113A1 (en) 2001-08-06 2003-02-20 Glenmark Pharmaceuticals Limited Novel benzopyran compounds and process for their preparation and use
ES2353021T3 (es) * 2004-03-23 2011-02-24 Nissan Chemical Industries, Ltd. Compuesto de benzopirano tricíclico como agentes anti-arrítmicos.

Also Published As

Publication number Publication date
TW200600509A (en) 2006-01-01
RU2380370C2 (ru) 2010-01-27
IL177950A (en) 2013-04-30
ES2353021T3 (es) 2011-02-24
EP1732929A1 (en) 2006-12-20
AU2005223612A1 (en) 2005-09-29
CA2558139A1 (en) 2005-09-29
ZA200607388B (en) 2008-07-30
AU2010202900A1 (en) 2010-07-29
AU2010202900B2 (en) 2011-10-27
RU2006137284A (ru) 2008-04-27
JP2007530436A (ja) 2007-11-01
NO339495B1 (no) 2016-12-19
KR101085979B1 (ko) 2011-11-22
RS51742B (sr) 2011-10-31
PL1732929T3 (pl) 2011-04-29
US20100069374A1 (en) 2010-03-18
MXPA06010880A (es) 2006-12-15
CN1934116A (zh) 2007-03-21
CY1111250T1 (el) 2015-06-11
JP4840594B2 (ja) 2011-12-21
WO2005090357A1 (en) 2005-09-29
CN101429200B (zh) 2012-05-30
AU2005223612B2 (en) 2010-06-24
HK1099299A1 (en) 2007-08-10
PT1732929E (pt) 2010-12-21
CA2558139C (en) 2012-01-17
KR101019402B1 (ko) 2011-03-07
KR20100130249A (ko) 2010-12-10
SK50792006A3 (sk) 2007-09-06
US20080004262A1 (en) 2008-01-03
IL177950A0 (en) 2006-12-31
SK287994B6 (sk) 2012-09-03
US7652008B2 (en) 2010-01-26
UA91189C2 (en) 2010-07-12
DE602005024245D1 (de) 2010-12-02
ATE485299T1 (de) 2010-11-15
KR20070009638A (ko) 2007-01-18
NO20064819L (no) 2006-10-23
CN101429200A (zh) 2009-05-13
HRP20110005T1 (hr) 2011-02-28
DK1732929T3 (da) 2010-12-20
TWI352704B (en) 2011-11-21
SI1732929T1 (sl) 2010-12-31
US7964623B2 (en) 2011-06-21
NZ585606A (en) 2011-11-25
EG27163A (en) 2015-08-24
EP1732929B1 (en) 2010-10-20
CN102190661A (zh) 2011-09-21
CN1934116B (zh) 2012-10-10
BRPI0508768A (pt) 2007-02-27
CN102190661B (zh) 2013-07-31
CZ2006598A3 (cs) 2006-11-15

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Legal Events

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PSEA Patent sealed
RENW Renewal (renewal fees accepted)
RENW Renewal (renewal fees accepted)
RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 3 YEARS UNTIL 23 MAR 2018 BY CPA GLOBAL

Effective date: 20140903

Free format text: PATENT RENEWED FOR 7 YEARS UNTIL 23 MAR 2025 BY CPA GLOBAL

Effective date: 20140906

EXPY Patent expired