NZ528370A - Beta-carboline derivatives and its pharmaceutical use against depression and anxiety - Google Patents
Beta-carboline derivatives and its pharmaceutical use against depression and anxietyInfo
- Publication number
- NZ528370A NZ528370A NZ528370A NZ52837002A NZ528370A NZ 528370 A NZ528370 A NZ 528370A NZ 528370 A NZ528370 A NZ 528370A NZ 52837002 A NZ52837002 A NZ 52837002A NZ 528370 A NZ528370 A NZ 528370A
- Authority
- NZ
- New Zealand
- Prior art keywords
- compound
- butyl
- phenyl
- acid addition
- free base
- Prior art date
Links
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0108337.7A GB0108337D0 (en) | 2001-04-03 | 2001-04-03 | Organic compounds |
| PCT/EP2002/003624 WO2002081471A1 (en) | 2001-04-03 | 2002-04-02 | Beta-carboline derivatives and its pharmaceutical use against depression and anxiety |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ528370A true NZ528370A (en) | 2005-10-28 |
Family
ID=9912165
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ528370A NZ528370A (en) | 2001-04-03 | 2002-04-02 | Beta-carboline derivatives and its pharmaceutical use against depression and anxiety |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US6861430B2 (enExample) |
| EP (1) | EP1377578B1 (enExample) |
| JP (1) | JP4405732B2 (enExample) |
| KR (1) | KR100564840B1 (enExample) |
| CN (1) | CN1309721C (enExample) |
| AR (1) | AR035451A1 (enExample) |
| AT (1) | ATE517104T1 (enExample) |
| AU (1) | AU2002316828B2 (enExample) |
| BR (1) | BR0208566B1 (enExample) |
| CA (1) | CA2440014C (enExample) |
| CZ (1) | CZ295992B6 (enExample) |
| EC (1) | ECSP034754A (enExample) |
| ES (1) | ES2368389T3 (enExample) |
| GB (1) | GB0108337D0 (enExample) |
| HU (1) | HUP0400317A3 (enExample) |
| IL (1) | IL157545A0 (enExample) |
| MX (1) | MXPA03009057A (enExample) |
| MY (1) | MY134026A (enExample) |
| NO (1) | NO20034413D0 (enExample) |
| NZ (1) | NZ528370A (enExample) |
| PE (1) | PE20021018A1 (enExample) |
| PL (1) | PL210861B1 (enExample) |
| PT (1) | PT1377578E (enExample) |
| RU (1) | RU2003130644A (enExample) |
| SK (1) | SK12222003A3 (enExample) |
| WO (1) | WO2002081471A1 (enExample) |
| ZA (1) | ZA200306108B (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10164139A1 (de) | 2001-12-27 | 2003-07-10 | Bayer Ag | 2-Heteroarylcarbonsäureamide |
| WO2004113300A1 (ja) * | 2003-06-23 | 2004-12-29 | Ono Pharmaceutical Co., Ltd. | 新規三環性複素環化合物 |
| AR051780A1 (es) * | 2004-11-29 | 2007-02-07 | Japan Tobacco Inc | Compuestos en anillo fusionados que contienen nitrogeno y utilizacion de los mismos |
| ES2459742T3 (es) | 2004-12-22 | 2014-05-12 | Ono Pharmaceutical Co., Ltd. | Compuesto tricíclico y uso del mismo |
| US20070149557A1 (en) * | 2005-11-21 | 2007-06-28 | Amgen Inc. | CXCR3 antagonists |
| US7879859B2 (en) * | 2005-11-21 | 2011-02-01 | Merck Sharp & Dohme Corp. | Diagnosis and treatment of type 2 diabetes and other disorders |
| JP2010533712A (ja) * | 2007-07-19 | 2010-10-28 | メルク・シャープ・エンド・ドーム・コーポレイション | 抗糖尿病化合物としてのベータカルボリン誘導体 |
| WO2009016329A1 (en) * | 2007-07-31 | 2009-02-05 | Cambridge Enterprise Limited | Use of gabaa receptor antagonists to treat cognitive impairment in patients with psychiatric conditions |
| US8338604B2 (en) | 2008-06-20 | 2012-12-25 | Bristol-Myers Squibb Company | Imidazopyridine and imidazopyrazine compounds useful as kinase inhibitors |
| CA2894860C (en) | 2008-11-19 | 2018-11-06 | Gerhard Koenig | Treatment of cognitive disorders with (r)-7-chloro-n-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide and pharmaceutically acceptable salts thereof |
| TW201028414A (en) * | 2009-01-16 | 2010-08-01 | Merck Sharp & Dohme | Oxadiazole beta carboline derivatives as antidiabetic compounds |
| JP2013517272A (ja) | 2010-01-15 | 2013-05-16 | メルク・シャープ・エンド・ドーム・コーポレイション | 抗糖尿病化合物としてのオキサジアゾール・ベータ・カルボリン誘導体 |
| MX357676B (es) | 2010-05-17 | 2018-07-18 | Forum Pharmaceuticals Inc | Una forma cristalina de clorhidrato de (r)-7-cloro-n-(quinuclidin- 3-il)benzo[b]tiofeno-2-carboxamida monohidratado. |
| EP3666272A1 (en) | 2012-05-08 | 2020-06-17 | Forum Pharmaceuticals Inc. | Use of encenicline in the treatment of cognitive impairment, alzheimer's disease, memory deficit |
| CN111349096B (zh) * | 2020-04-14 | 2021-03-09 | 石河子大学 | 一种吲哚类化合物及其制备方法、应用 |
| KR102467844B1 (ko) | 2021-04-21 | 2022-11-16 | 삼성전자주식회사 | 솔리드 스테이트 드라이브 장치 및 이를 포함하는 데이터 저장 장치 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4118741A1 (de) * | 1991-06-05 | 1992-12-10 | Schering Ag | Neue hetaryloxy-(beta)-carboline, deren herstellung und verwendung in arzneimitteln |
| US6057340A (en) * | 1998-02-03 | 2000-05-02 | American Home Products Corporation | Oxazole derivatives as serotonin-1A receptor agonists |
| ES2188184T3 (es) | 1998-06-12 | 2003-06-16 | Sod Conseils Rech Applic | Compuestos de beta-carbolinas. |
-
2001
- 2001-04-03 GB GBGB0108337.7A patent/GB0108337D0/en not_active Ceased
-
2002
- 2002-03-27 AR ARP020101141A patent/AR035451A1/es not_active Application Discontinuation
- 2002-04-02 CA CA2440014A patent/CA2440014C/en not_active Expired - Fee Related
- 2002-04-02 BR BRPI0208566-6B1A patent/BR0208566B1/pt not_active IP Right Cessation
- 2002-04-02 NZ NZ528370A patent/NZ528370A/en not_active IP Right Cessation
- 2002-04-02 PT PT02745204T patent/PT1377578E/pt unknown
- 2002-04-02 HU HU0400317A patent/HUP0400317A3/hu unknown
- 2002-04-02 US US10/472,630 patent/US6861430B2/en not_active Expired - Fee Related
- 2002-04-02 ES ES02745204T patent/ES2368389T3/es not_active Expired - Lifetime
- 2002-04-02 CZ CZ20032655A patent/CZ295992B6/cs not_active IP Right Cessation
- 2002-04-02 IL IL15754502A patent/IL157545A0/xx unknown
- 2002-04-02 JP JP2002579459A patent/JP4405732B2/ja not_active Expired - Fee Related
- 2002-04-02 EP EP02745204A patent/EP1377578B1/en not_active Expired - Lifetime
- 2002-04-02 RU RU2003130644/04A patent/RU2003130644A/ru not_active Application Discontinuation
- 2002-04-02 WO PCT/EP2002/003624 patent/WO2002081471A1/en not_active Ceased
- 2002-04-02 PL PL362571A patent/PL210861B1/pl not_active IP Right Cessation
- 2002-04-02 MY MYPI20021189A patent/MY134026A/en unknown
- 2002-04-02 AT AT02745204T patent/ATE517104T1/de active
- 2002-04-02 PE PE2002000264A patent/PE20021018A1/es not_active Application Discontinuation
- 2002-04-02 KR KR1020037012933A patent/KR100564840B1/ko not_active Expired - Fee Related
- 2002-04-02 MX MXPA03009057A patent/MXPA03009057A/es active IP Right Grant
- 2002-04-02 AU AU2002316828A patent/AU2002316828B2/en not_active Ceased
- 2002-04-02 SK SK1222-2003A patent/SK12222003A3/sk not_active Application Discontinuation
- 2002-04-02 CN CNB028077814A patent/CN1309721C/zh not_active Expired - Fee Related
-
2003
- 2003-08-07 ZA ZA200306108A patent/ZA200306108B/en unknown
- 2003-08-27 EC EC2003004754A patent/ECSP034754A/es unknown
- 2003-10-02 NO NO20034413A patent/NO20034413D0/no not_active Application Discontinuation
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| Date | Code | Title | Description |
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| PSEA | Patent sealed | ||
| RENW | Renewal (renewal fees accepted) | ||
| RENW | Renewal (renewal fees accepted) | ||
| RENW | Renewal (renewal fees accepted) | ||
| LAPS | Patent lapsed |