BR0208566B1 - Derivados de Beta-Carbolina, Seu Uso, e composição Farmacêutica - Google Patents

Derivados de Beta-Carbolina, Seu Uso, e composição Farmacêutica

Info

Publication number
BR0208566B1
BR0208566B1 BRPI0208566-6B1A BR0208566A BR0208566B1 BR 0208566 B1 BR0208566 B1 BR 0208566B1 BR 0208566 A BR0208566 A BR 0208566A BR 0208566 B1 BR0208566 B1 BR 0208566B1
Authority
BR
Brazil
Prior art keywords
beta
pharmaceutical composition
carboline derivatives
carboline
derivatives
Prior art date
Application number
BRPI0208566-6B1A
Other languages
English (en)
Portuguese (pt)
Other versions
BR0208566A (pt
Inventor
Thomas J Troxler
Konstanze Hurth
Daniel Hoyer
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of BR0208566A publication Critical patent/BR0208566A/pt
Publication of BR0208566B1 publication Critical patent/BR0208566B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BRPI0208566-6B1A 2001-04-03 2002-04-02 Derivados de Beta-Carbolina, Seu Uso, e composição Farmacêutica BR0208566B1 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0108337.7A GB0108337D0 (en) 2001-04-03 2001-04-03 Organic compounds
PCT/EP2002/003624 WO2002081471A1 (en) 2001-04-03 2002-04-02 Beta-carboline derivatives and its pharmaceutical use against depression and anxiety

Publications (2)

Publication Number Publication Date
BR0208566A BR0208566A (pt) 2004-03-30
BR0208566B1 true BR0208566B1 (pt) 2013-12-24

Family

ID=9912165

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0208566-6B1A BR0208566B1 (pt) 2001-04-03 2002-04-02 Derivados de Beta-Carbolina, Seu Uso, e composição Farmacêutica

Country Status (27)

Country Link
US (1) US6861430B2 (enExample)
EP (1) EP1377578B1 (enExample)
JP (1) JP4405732B2 (enExample)
KR (1) KR100564840B1 (enExample)
CN (1) CN1309721C (enExample)
AR (1) AR035451A1 (enExample)
AT (1) ATE517104T1 (enExample)
AU (1) AU2002316828B2 (enExample)
BR (1) BR0208566B1 (enExample)
CA (1) CA2440014C (enExample)
CZ (1) CZ295992B6 (enExample)
EC (1) ECSP034754A (enExample)
ES (1) ES2368389T3 (enExample)
GB (1) GB0108337D0 (enExample)
HU (1) HUP0400317A3 (enExample)
IL (1) IL157545A0 (enExample)
MX (1) MXPA03009057A (enExample)
MY (1) MY134026A (enExample)
NO (1) NO20034413D0 (enExample)
NZ (1) NZ528370A (enExample)
PE (1) PE20021018A1 (enExample)
PL (1) PL210861B1 (enExample)
PT (1) PT1377578E (enExample)
RU (1) RU2003130644A (enExample)
SK (1) SK12222003A3 (enExample)
WO (1) WO2002081471A1 (enExample)
ZA (1) ZA200306108B (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10164139A1 (de) 2001-12-27 2003-07-10 Bayer Ag 2-Heteroarylcarbonsäureamide
ES2427166T3 (es) * 2003-06-23 2013-10-29 Ono Pharmaceutical Co., Ltd. Compuesto heterocíclico tricíclico novedoso
AR051780A1 (es) * 2004-11-29 2007-02-07 Japan Tobacco Inc Compuestos en anillo fusionados que contienen nitrogeno y utilizacion de los mismos
PT1829874E (pt) 2004-12-22 2014-04-10 Ono Pharmaceutical Co Composto tricíclico e sua utilização
WO2007062175A2 (en) * 2005-11-21 2007-05-31 Amgen Inc. Spiro-substituted tricyclic heterocycles cxcr3 antagonists
US7879859B2 (en) 2005-11-21 2011-02-01 Merck Sharp & Dohme Corp. Diagnosis and treatment of type 2 diabetes and other disorders
CA2693214A1 (en) * 2007-07-19 2009-01-22 Merck Sharp & Dohme Corp. Beta carboline derivatives as antidiabetic compounds
WO2009016329A1 (en) * 2007-07-31 2009-02-05 Cambridge Enterprise Limited Use of gabaa receptor antagonists to treat cognitive impairment in patients with psychiatric conditions
CN102131805A (zh) 2008-06-20 2011-07-20 百时美施贵宝公司 用作激酶抑制剂的咪唑并吡啶和咪唑并吡嗪化合物
EP2355822B1 (en) 2008-11-19 2012-10-10 Envivo Pharmaceuticals, Inc. Treatment of cognitive disorders with (r)-7-chloro-n-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide and pharmaceutically acceptable salts thereof
TW201028414A (en) * 2009-01-16 2010-08-01 Merck Sharp & Dohme Oxadiazole beta carboline derivatives as antidiabetic compounds
WO2011088025A1 (en) 2010-01-15 2011-07-21 Merck Sharp & Dohme Corp. Oxadiazole beta carboline derivatives as antidiabetic compounds
RS54742B1 (sr) 2010-05-17 2016-10-31 Forum Pharmaceuticals Inc Kristalni oblik (r)-7-hlor-n-(hinuklidin-3-il)benzo[b]tiofen-2-karboksamid hidrohlorid monohidrata
US9585877B2 (en) 2012-05-08 2017-03-07 Forum Pharmaceuticals, Inc. Methods of maintaining, treating or improving cognitive function
CN111349096B (zh) * 2020-04-14 2021-03-09 石河子大学 一种吲哚类化合物及其制备方法、应用
KR102467844B1 (ko) 2021-04-21 2022-11-16 삼성전자주식회사 솔리드 스테이트 드라이브 장치 및 이를 포함하는 데이터 저장 장치

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4118741A1 (de) * 1991-06-05 1992-12-10 Schering Ag Neue hetaryloxy-(beta)-carboline, deren herstellung und verwendung in arzneimitteln
US6057340A (en) * 1998-02-03 2000-05-02 American Home Products Corporation Oxazole derivatives as serotonin-1A receptor agonists
ATE229954T1 (de) 1998-06-12 2003-01-15 Sod Conseils Rech Applic Betacarbolinverbindungen

Also Published As

Publication number Publication date
ZA200306108B (en) 2004-07-05
BR0208566A (pt) 2004-03-30
WO2002081471A1 (en) 2002-10-17
KR100564840B1 (ko) 2006-03-28
GB0108337D0 (en) 2001-05-23
NO20034413L (no) 2003-10-02
RU2003130644A (ru) 2005-04-10
MXPA03009057A (es) 2004-02-12
MY134026A (en) 2007-11-30
CN1500090A (zh) 2004-05-26
SK12222003A3 (sk) 2004-06-08
HUP0400317A3 (en) 2007-10-29
US20040132735A1 (en) 2004-07-08
CZ295992B6 (cs) 2005-12-14
PL362571A1 (en) 2004-11-02
ES2368389T3 (es) 2011-11-16
HUP0400317A2 (hu) 2004-09-28
AR035451A1 (es) 2004-05-26
ECSP034754A (es) 2003-10-28
CA2440014A1 (en) 2002-10-17
IL157545A0 (en) 2004-03-28
US6861430B2 (en) 2005-03-01
EP1377578B1 (en) 2011-07-20
ATE517104T1 (de) 2011-08-15
CA2440014C (en) 2010-11-23
PL210861B1 (pl) 2012-03-30
JP4405732B2 (ja) 2010-01-27
CZ20032655A3 (cs) 2003-12-17
AU2002316828B2 (en) 2006-05-11
PT1377578E (pt) 2011-09-23
EP1377578A1 (en) 2004-01-07
NO20034413D0 (no) 2003-10-02
KR20040008150A (ko) 2004-01-28
JP2004525178A (ja) 2004-08-19
PE20021018A1 (es) 2003-01-13
NZ528370A (en) 2005-10-28
CN1309721C (zh) 2007-04-11

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 24/12/2013, OBSERVADAS AS CONDICOES LEGAIS.

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 13A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2307 DE 24-03-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.