NZ334448A - olanzapine dihydrate which can be used in a process for preparing olanzapine - Google Patents

olanzapine dihydrate which can be used in a process for preparing olanzapine

Info

Publication number
NZ334448A
NZ334448A NZ334448A NZ33444897A NZ334448A NZ 334448 A NZ334448 A NZ 334448A NZ 334448 A NZ334448 A NZ 334448A NZ 33444897 A NZ33444897 A NZ 33444897A NZ 334448 A NZ334448 A NZ 334448A
Authority
NZ
New Zealand
Prior art keywords
dihydrate
olanzapine
compound
pct
mimosa
Prior art date
Application number
NZ334448A
Other languages
English (en)
Inventor
Charles A Bunnell
Samuel D Larsen
John R Nichols
Susan M Reutzel
Gregory A Stephenson
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21832120&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NZ334448(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of NZ334448A publication Critical patent/NZ334448A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NZ334448A 1996-09-23 1997-09-18 olanzapine dihydrate which can be used in a process for preparing olanzapine NZ334448A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2648796P 1996-09-23 1996-09-23
PCT/US1997/016499 WO1998012199A1 (en) 1996-09-23 1997-09-18 Intermediates and process for preparing olanzapine

Publications (1)

Publication Number Publication Date
NZ334448A true NZ334448A (en) 2000-08-25

Family

ID=21832120

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ334448A NZ334448A (en) 1996-09-23 1997-09-18 olanzapine dihydrate which can be used in a process for preparing olanzapine

Country Status (35)

Country Link
US (1) US6020487A (en:Method)
EP (1) EP0831098B1 (en:Method)
JP (2) JP2001500877A (en:Method)
KR (1) KR100560015B1 (en:Method)
CN (1) CN1122036C (en:Method)
AR (1) AR013838A1 (en:Method)
AT (1) ATE209208T1 (en:Method)
AU (1) AU719441B2 (en:Method)
BR (1) BR9712100A (en:Method)
CA (1) CA2265712C (en:Method)
CO (1) CO4910140A1 (en:Method)
CZ (1) CZ299248B6 (en:Method)
DE (1) DE69708428T2 (en:Method)
DK (1) DK0831098T3 (en:Method)
EA (1) EA001642B1 (en:Method)
EG (1) EG23861A (en:Method)
ES (1) ES2166051T3 (en:Method)
HU (1) HU226484B1 (en:Method)
ID (1) ID27275A (en:Method)
IL (1) IL128962A (en:Method)
IN (1) IN187156B (en:Method)
MY (1) MY125565A (en:Method)
NO (1) NO323980B1 (en:Method)
NZ (1) NZ334448A (en:Method)
PE (1) PE110398A1 (en:Method)
PL (3) PL196069B1 (en:Method)
PT (1) PT831098E (en:Method)
RS (1) RS49598B (en:Method)
SI (1) SI0831098T1 (en:Method)
SV (1) SV1997000081A (en:Method)
TR (1) TR199900640T2 (en:Method)
TW (1) TW470746B (en:Method)
UA (1) UA59371C2 (en:Method)
WO (1) WO1998012199A1 (en:Method)
ZA (1) ZA978515B (en:Method)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1313742A1 (en) * 2000-08-31 2003-05-28 Dr. Reddy's Laboratories Ltd. Process for preparation of hydrates of olanzapine and their conversion into crystalline forms of olanzapine
US6740753B2 (en) * 2001-01-04 2004-05-25 Geneva Pharmaceuticals, Inc. Olanzapine crystal modification
CA2464306A1 (en) * 2001-10-29 2003-05-08 Dr. Reddy's Laboratories Ltd. Olanzapine dihydrate-ii a process for its preparation and use thereof
JP4530664B2 (ja) 2001-12-24 2010-08-25 サン・ファーマシューティカル・インダストリーズ・リミテッド ２−メチル−４−（４−メチル−１−ピペラジニル）−１０Ｈ−チエノ［２，３−ｂ］［１，５］ベンゾジアゼピンの結晶形Ｉ、この結晶形Ｉの製造方法、及び医薬組成物
WO2003091260A1 (en) * 2002-04-23 2003-11-06 Dr. Reddy's Laboratories Limited Novel crystalline polymorph form-vi of olanzapine and a process for preparation thereof
SI1513846T1 (sl) * 2002-05-31 2011-11-30 Sandoz Ag Postopek za pripravo olanzapina form I
SI21270A (sl) 2002-07-15 2004-02-29 Krka, Tovarna Zdravil, D.D., Novo Mesto Kristalne oblike olanzapina in postopki za njihovo pripravo
US7323459B2 (en) 2002-12-24 2008-01-29 Teva Pharmaceutical Industries Ltd. Crystal forms, methods for their preparation and method for preparation of olanzapine
EP1684734A2 (en) * 2003-11-18 2006-08-02 3M Innovative Properties Company Olanzapine containing transdermal drug delivery compositions
CN1906201A (zh) * 2003-12-22 2007-01-31 特瓦制药工业有限公司 合成奥氮平的方法
ATE504588T1 (de) 2004-01-27 2011-04-15 Synthon Bv Stabile salze von olanzapin
WO2005080401A1 (en) * 2004-02-19 2005-09-01 Neuland Laboratories Limited Process for the preparation of olanzapine form 1 useful as antipsychotic drug
ES2289974T1 (es) * 2004-07-14 2008-02-16 Shasun Chemicals And Drugs Limited Metodo mejorado para producir la forma i de la olanzapina.
ES2253091B1 (es) 2004-07-27 2007-02-01 Inke, S.A. Solvato mixto de olanzapina, procedimiento para su obtencion y procedimiento de obtencion de la forma i de olanzapina a partir del mismo.
WO2006027800A1 (en) * 2004-09-06 2006-03-16 Shasun Chemicals And Drugs Limited A novel process for preparation of a pharmaceutically pure polymorphic form 1 of olanzapine
AU2005307797B2 (en) * 2004-11-16 2011-06-02 Alkermes Pharma Ireland Limited Injectable nanoparticulate olanzapine formulations
US7834176B2 (en) 2006-01-26 2010-11-16 Sandoz Ag Polymorph E of Olanzapine and preparation of anhydrous non-solvated crystalline polymorphic Form I of 2-methyl-4(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5] benzodiazepine (Olanzapine Form I) from the polymorphic Olanzapine Form E
CA2591644A1 (en) * 2007-06-14 2008-12-14 Apotex Pharmachem Inc. Novel processes to form-i of olanzapine
EP2486913A1 (en) 2011-02-14 2012-08-15 Labtec GmbH Rapidly disintegrating oral film formulation for Olanzapin
JP6008734B2 (ja) * 2012-12-20 2016-10-19 株式会社トクヤマ オランザピンｉｉ型結晶の製造方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5302716A (en) * 1986-01-16 1994-04-12 Schering Corporation Fused benzazepines
CA2002596A1 (en) * 1988-11-14 1990-05-14 Thomas M. Eckrich Hydrates of b-lactam antibiotic
GB9009229D0 (en) * 1990-04-25 1990-06-20 Lilly Industries Ltd Pharmaceutical compounds
US5229382A (en) * 1990-04-25 1993-07-20 Lilly Industries Limited 2-methyl-thieno-benzodiazepine
AU668159B2 (en) * 1992-05-29 1996-04-26 Lilly Industries Limited Pharmaceutical compounds
US5550231A (en) * 1993-06-15 1996-08-27 Eli Lilly And Company Loracarbef hydrochloride C1-C3 alcohol solvates and uses thereof
US5602124A (en) * 1994-12-12 1997-02-11 Allelix Biopharmaceuticals, Inc. 5-HT2 receptor ligands
EG24221A (en) * 1995-03-24 2008-11-10 Lilly Co Eli Process for preparing olanzapine
US5637584A (en) * 1995-03-24 1997-06-10 Eli Lilly And Company Solvate of olanzapine
US5631250A (en) * 1995-03-24 1997-05-20 Eli Lilly And Company Process and solvate of 2-methyl-thieno-benzodiazepine
EG23659A (en) * 1995-03-24 2007-03-26 Lilly Co Eli Process and crystal forms of methyl-thieno-benzodiazepine
TR199900639T2 (xx) * 1996-09-23 1999-06-21 Eli Lilly And Company Olanzapin dihidrat D.

Also Published As

Publication number Publication date
EG23861A (en) 2007-11-18
EP0831098A3 (en) 1998-04-29
ZA978515B (en) 1999-03-23
YU15599A (sh) 2001-12-26
IL128962A0 (en) 2000-02-17
RS49598B (sr) 2007-06-04
MY125565A (en) 2006-08-30
SI0831098T1 (en) 2002-04-30
HK1009807A1 (en) 1999-06-11
NO323980B1 (no) 2007-07-30
DE69708428T2 (de) 2002-07-04
CO4910140A1 (es) 2000-04-24
ATE209208T1 (de) 2001-12-15
DE69708428D1 (de) 2002-01-03
DK0831098T3 (da) 2002-05-21
PL332482A1 (en) 1999-09-13
HU226484B1 (en) 2009-03-02
IL128962A (en) 2003-01-12
EP0831098B1 (en) 2001-11-21
CA2265712A1 (en) 1998-03-26
CZ99099A3 (cs) 1999-11-17
ES2166051T3 (es) 2002-04-01
CN1122036C (zh) 2003-09-24
AR013838A1 (es) 2001-01-31
PL196069B1 (pl) 2007-12-31
TW470746B (en) 2002-01-01
PL196068B1 (pl) 2007-12-31
NO991382D0 (no) 1999-03-22
HUP0000066A2 (hu) 2000-06-28
NO991382L (no) 1999-03-22
KR100560015B1 (ko) 2006-03-15
EA199900326A1 (ru) 1999-08-26
JP2001500877A (ja) 2001-01-23
CZ299248B6 (cs) 2008-05-28
CN1234802A (zh) 1999-11-10
HUP0000066A3 (en) 2000-11-28
JP2009242407A (ja) 2009-10-22
BR9712100A (pt) 1999-08-31
PT831098E (pt) 2002-04-29
PL194565B1 (pl) 2007-06-29
EP0831098A2 (en) 1998-03-25
SV1997000081A (es) 1999-01-14
IN187156B (en:Method) 2002-02-16
UA59371C2 (uk) 2003-09-15
CA2265712C (en) 2006-10-31
PE110398A1 (es) 1999-01-14
TR199900640T2 (xx) 1999-06-21
WO1998012199A1 (en) 1998-03-26
AU4484197A (en) 1998-04-14
US6020487A (en) 2000-02-01
ID27275A (id) 2001-03-22
KR20000048520A (ko) 2000-07-25
EA001642B1 (ru) 2001-06-25
AU719441B2 (en) 2000-05-11

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Legal Events

Date Code Title Description
RENW Renewal (renewal fees accepted)
RENW Renewal (renewal fees accepted)
LCEA Licensees added

Name of requester: ELI LILLY AND COMPANY (NZ) LIMITED

RENW Renewal (renewal fees accepted)
RENW Renewal (renewal fees accepted)
EXPY Patent expired