ATE504588T1 - Stabile salze von olanzapin - Google Patents

Stabile salze von olanzapin

Info

Publication number
ATE504588T1
ATE504588T1 AT05707055T AT05707055T ATE504588T1 AT E504588 T1 ATE504588 T1 AT E504588T1 AT 05707055 T AT05707055 T AT 05707055T AT 05707055 T AT05707055 T AT 05707055T AT E504588 T1 ATE504588 T1 AT E504588T1
Authority
AT
Austria
Prior art keywords
olanzapine
stable salts
salts
stable
Prior art date
Application number
AT05707055T
Other languages
English (en)
Inventor
Rolf Keltjens
Original Assignee
Synthon Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthon Bv filed Critical Synthon Bv
Application granted granted Critical
Publication of ATE504588T1 publication Critical patent/ATE504588T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
AT05707055T 2004-01-27 2005-01-26 Stabile salze von olanzapin ATE504588T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US53912004P 2004-01-27 2004-01-27
US56960704P 2004-05-11 2004-05-11
PCT/EP2005/000835 WO2005070938A1 (en) 2004-01-27 2005-01-26 Stable salts of olanzapine

Publications (1)

Publication Number Publication Date
ATE504588T1 true ATE504588T1 (de) 2011-04-15

Family

ID=34811365

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05707055T ATE504588T1 (de) 2004-01-27 2005-01-26 Stabile salze von olanzapin

Country Status (6)

Country Link
US (2) US7459449B2 (de)
EP (1) EP1709053B1 (de)
AR (1) AR047459A1 (de)
AT (1) ATE504588T1 (de)
DE (1) DE602005027308D1 (de)
WO (1) WO2005070938A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050025791A1 (en) 2002-06-21 2005-02-03 Julius Remenar Pharmaceutical compositions with improved dissolution
US7927613B2 (en) * 2002-02-15 2011-04-19 University Of South Florida Pharmaceutical co-crystal compositions
US7790905B2 (en) 2002-02-15 2010-09-07 Mcneil-Ppc, Inc. Pharmaceutical propylene glycol solvate compositions
AU2003213719A1 (en) 2002-03-01 2003-09-16 Regents Of The University Of Michigan Multiple-component solid phases containing at least one active pharmaceutical ingredient
EP1575962A1 (de) * 2002-12-24 2005-09-21 Teva Pharmaceutical Industries Limited Neue kristallformen von olanzapin, verfahren zu deren herstellung und verfahren zur herstellung bekannter kristallformen von olanzapin
US8183290B2 (en) 2002-12-30 2012-05-22 Mcneil-Ppc, Inc. Pharmaceutically acceptable propylene glycol solvate of naproxen
HU226410B1 (en) * 2003-04-22 2008-11-28 Egis Gyogyszergyar Nyilvanosan Novel polymorphous forms of olanzapine hydrochlorides, process for producing them, use thereof and pharmaceutical compositions containing them
AR047459A1 (es) * 2004-01-27 2006-01-18 Synthon Bv Sales estables de 2-metil-4-(4-metil-1-piperazinil)-10h-tieno[2,3-b][1,5]benzodiazepina (olanzapina)
US20050272720A1 (en) * 2004-01-27 2005-12-08 Rolf Keltjens Process for making olanzapine Form I
AR048272A1 (es) * 2004-03-18 2006-04-12 Lek Pharmaceuticals Sintesis de 2 metil - 4- (4- metil -1- piperazinil) - 10 h- tieno ( 2,3-b) (1,5) benzodiazepina y sus sales, metodos para su preparacion, composiciones farmaceuticas que la contienen y su uso en la fabricacion de medicamentos para el tratamiento de enfermedades mentales.
EP1919923A1 (de) * 2005-08-17 2008-05-14 Synthon B.V. Verfahren zur herstellung von olanzapin form i
PL377084A1 (pl) * 2005-09-15 2007-03-19 Koźluk Tomasz Nobilus Ent Nowe związki olanzapiny i sposób ich wytwarzania
ES2279715B1 (es) 2005-12-26 2008-06-01 Laboratorios Lesvi, S.L. Formulacion oral de olanzapina.
US20070293479A1 (en) * 2006-05-18 2007-12-20 Osinga Niels J Olanzapine pharmaceutical composition
AR063043A1 (es) * 2006-09-29 2008-12-23 Synthon Bv Composicion farmaceutica de olanzapina
ES2615884T3 (es) * 2009-01-20 2017-06-08 Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center Ácido sórbico y benzoico y sus derivados que aumentan la actividad de un neurofármaco
WO2010100658A2 (en) * 2009-03-05 2010-09-10 Genepharm India Private Limited Stable olanzapine tablets and the process for its preparation
AU2010324810B2 (en) 2009-11-27 2016-05-12 Genzyme Corporation An amorphous and a crystalline form of genz 112638 hemitartrate as inhibitor of glucosylceramide synthase
CN103211797B (zh) * 2012-01-18 2017-06-06 北京天衡医院管理有限公司 盐酸维拉帕米膜控缓释微丸胶囊
CA3027297A1 (en) 2016-06-13 2017-12-21 Syneurx International (Taiwan) Corp. Co-crystals of sodium benzoate and uses thereof
TWI736635B (zh) 2016-06-13 2021-08-21 心悅生醫股份有限公司 苯甲酸鋰之共晶及其用途
US11369579B2 (en) 2016-10-24 2022-06-28 Syneurx International (Taiwan) Corp. Polymorphic forms of sodium benzoate and uses thereof
US10336679B2 (en) 2016-10-24 2019-07-02 Syneurx International (Taiwan) Corp. Polymorphic forms of sodium benzoate and uses thereof
US10098861B1 (en) 2017-10-24 2018-10-16 Syneurx International (Taiwan) Corp. Pharmaceutical composition comprising sodium benzoate compound and clozapine, and uses thereof
TWI803867B (zh) * 2020-05-05 2023-06-01 心悅生醫股份有限公司 神經藥物的鹽類及其用途

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4115568A (en) 1974-11-26 1978-09-19 Lilly Industries Limited Thieno[3,2-b]-[1,5]benzodiazepines
US5229382A (en) 1990-04-25 1993-07-20 Lilly Industries Limited 2-methyl-thieno-benzodiazepine
GB9009229D0 (en) 1990-04-25 1990-06-20 Lilly Industries Ltd Pharmaceutical compounds
US5605897A (en) 1991-04-23 1997-02-25 Eli Lilly And Company 2-methyl-thieno-benzodiazepine
US5457101A (en) * 1994-06-03 1995-10-10 Eli Lilly And Company Thieno[1,5]benzoidiazepine use
GB9423511D0 (en) 1994-11-22 1995-01-11 Glaxo Wellcome Inc Compositions
EG23659A (en) 1995-03-24 2007-03-26 Lilly Co Eli Process and crystal forms of methyl-thieno-benzodiazepine
ATE220550T1 (de) 1995-05-30 2002-08-15 Lilly Co Eli Verfahren zur behandlung von wahrnehmungsstörungen
ZA978515B (en) 1996-09-23 1999-03-23 Lilly Co Eli Intermediates and process for preparing olanzapine
KR100516088B1 (ko) 1996-09-23 2005-09-22 일라이 릴리 앤드 캄파니 올란자핀 이수화물 ｄ
IL135295A0 (en) 1997-09-30 2001-05-20 Lilly Co Eli 2-methyl-thieno-benzodiazepine formulation
AU9583498A (en) * 1997-09-30 1999-04-23 Eli Lilly And Company Method for treating sexual dysfunction
US6348458B1 (en) 1999-12-28 2002-02-19 U & I Pharmaceuticals Ltd. Polymorphic forms of olanzapine
CA2395774C (en) 1999-12-28 2009-09-15 Cipla Limited New polymorphic forms of olanzapine
CZ2003566A3 (cs) 2000-08-31 2004-01-14 Dr. Reddy's Laboratories Ltd. Způsob přípravy hydrátů olanzapinu a jejich konverze na krystalické formy olanzapinu
US6740753B2 (en) * 2001-01-04 2004-05-25 Geneva Pharmaceuticals, Inc. Olanzapine crystal modification
UA80095C2 (en) 2001-07-20 2007-08-27 Lilly Co Eli 2 methyl-thieno-benzodiazepine lyophilized formulation and method for the preparation thereof
WO2003091260A1 (en) 2002-04-23 2003-11-06 Dr. Reddy's Laboratories Limited Novel crystalline polymorph form-vi of olanzapine and a process for preparation thereof
PL196814B1 (pl) 2002-05-17 2008-02-29 Inst Farmaceutyczny Sposób wytwarzania odmiany polimorficznej I olanzapiny i jej solwaty
US7297789B2 (en) 2002-05-31 2007-11-20 Sandoz, Inc. Process of preparation of olanzapine form I
PL199016B1 (pl) 2002-06-20 2008-08-29 Adamed Sp Z Oo Sposób wytwarzania olanzapiny
SI21270A (sl) 2002-07-15 2004-02-29 Krka, Tovarna Zdravil, D.D., Novo Mesto Kristalne oblike olanzapina in postopki za njihovo pripravo
US20040265375A1 (en) 2003-04-16 2004-12-30 Platteeuw Johannes J. Orally disintegrating tablets
US20050272720A1 (en) * 2004-01-27 2005-12-08 Rolf Keltjens Process for making olanzapine Form I
AR047459A1 (es) 2004-01-27 2006-01-18 Synthon Bv Sales estables de 2-metil-4-(4-metil-1-piperazinil)-10h-tieno[2,3-b][1,5]benzodiazepina (olanzapina)

Also Published As

Publication number Publication date
US20050272721A1 (en) 2005-12-08
AR047459A1 (es) 2006-01-18
US7459449B2 (en) 2008-12-02
WO2005070938A1 (en) 2005-08-04
EP1709053A1 (de) 2006-10-11
US7329747B2 (en) 2008-02-12
EP1709053B1 (de) 2011-04-06
US20050267099A1 (en) 2005-12-01
DE602005027308D1 (de) 2011-05-19

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Legal Events

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